Details for gene set HALLMARK_INTERFERON_GAMMA_RESPONSE[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	HALLMARK_INTERFERON_GAMMA_RESPONSE
Enrichment Score (ES)	0.3091342
Normalized Enrichment Score (NES)	1.4937812
Nominal p-value	0.0028490028
FDR q-value	0.045410134
FWER p-Value	0.316

Fig 1: Enrichment plot: HALLMARK_INTERFERON_GAMMA_RESPONSE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RNF31	ENSG00000092098.17			528	1.004	0.0019	Yes
2	SECTM1	ENSG00000141574.8			720	0.934	0.0110	Yes
3	IRF7	ENSG00000185507.21			812	0.910	0.0222	Yes
4	PTGS2	ENSG00000073756.12			1105	0.837	0.0274	Yes
5	IFI44L	ENSG00000137959.16			1186	0.820	0.0375	Yes
6	IRF4	ENSG00000137265.15			1229	0.811	0.0485	Yes
7	C1S	ENSG00000182326.15			1233	0.811	0.0604	Yes
8	IDO1	ENSG00000131203.13			1274	0.806	0.0713	Yes
9	FCGR1A	ENSG00000150337.13			1585	0.761	0.0749	Yes
10	XAF1	ENSG00000132530.17			1598	0.759	0.0858	Yes
11	IRF5	ENSG00000128604.20			1851	0.724	0.0903	Yes
12	CCL7	ENSG00000108688.11			1881	0.720	0.1002	Yes
13	OASL	ENSG00000135114.12			1975	0.708	0.1084	Yes
14	CFH	ENSG00000000971.15			2168	0.686	0.1138	Yes
15	IL2RB	ENSG00000100385.14			2208	0.683	0.1229	Yes
16	BANK1	ENSG00000153064.12			2390	0.663	0.1283	Yes
17	RAPGEF6	ENSG00000158987.21			2692	0.634	0.1303	Yes
18	MX1	ENSG00000157601.14			2878	0.616	0.1349	Yes
19	TNFAIP2	ENSG00000185215.9			2924	0.612	0.1428	Yes
20	C1R	ENSG00000159403.18			2987	0.607	0.1502	Yes
21	RTP4	ENSG00000136514.3			3190	0.592	0.1540	Yes
22	STAT3	ENSG00000168610.14			3305	0.583	0.1598	Yes
23	IL18BP	ENSG00000137496.18			3360	0.579	0.1670	Yes
24	OAS3	ENSG00000111331.13			3389	0.577	0.1749	Yes
25	METTL7B	ENSG00000170439.7			3426	0.573	0.1824	Yes
26	RSAD2	ENSG00000134321.12			3652	0.561	0.1852	Yes
27	USP18	ENSG00000184979.10			3745	0.554	0.1911	Yes
28	MT2A	ENSG00000125148.7			3939	0.543	0.1944	Yes
29	IFIH1	ENSG00000115267.8			3962	0.542	0.2019	Yes
30	HELZ2	ENSG00000130589.16			4036	0.539	0.2080	Yes
31	PDE4B	ENSG00000184588.18			4101	0.537	0.2144	Yes
32	LCP2	ENSG00000043462.12			4413	0.519	0.2144	Yes
33	PLA2G4A	ENSG00000116711.10			4587	0.514	0.2178	Yes
34	CD38	ENSG00000004468.13			4696	0.511	0.2227	Yes
35	CFB	ENSG00000243649.8			4800	0.504	0.2276	Yes
36	CIITA	ENSG00000179583.19			5000	0.491	0.2300	Yes
37	IRF9	ENSG00000213928.9			5089	0.484	0.2350	Yes
38	NOD1	ENSG00000106100.11			5252	0.474	0.2380	Yes
39	NAMPT	ENSG00000105835.12			5278	0.473	0.2444	Yes
40	PELI1	ENSG00000197329.12			5372	0.467	0.2490	Yes
41	CMPK2	ENSG00000134326.11			5565	0.456	0.2510	Yes
42	GPR18	ENSG00000125245.12			5937	0.437	0.2484	Yes
43	OAS2	ENSG00000111335.12			5951	0.436	0.2545	Yes
44	NLRC5	ENSG00000140853.15			5975	0.434	0.2604	Yes
45	EPSTI1	ENSG00000133106.14			6091	0.429	0.2639	Yes
46	DDX60	ENSG00000137628.17			6234	0.421	0.2666	Yes
47	GCH1	ENSG00000131979.19			6236	0.421	0.2728	Yes
48	TNFSF10	ENSG00000121858.11			6380	0.413	0.2754	Yes
49	UPP1	ENSG00000183696.14			6504	0.408	0.2784	Yes
50	HERC6	ENSG00000138642.14			6720	0.400	0.2791	Yes
51	HLA-B	ENSG00000234745.11			6725	0.399	0.2848	Yes
52	ISG20	ENSG00000172183.15			6772	0.397	0.2896	Yes
53	DHX58	ENSG00000108771.13			7021	0.388	0.2892	Yes
54	CMKLR1	ENSG00000174600.14			7266	0.377	0.2888	Yes
55	BTG1	ENSG00000133639.5			7649	0.365	0.2849	Yes
56	HLA-A	ENSG00000206503.13			8022	0.360	0.2811	Yes
57	HLA-G	ENSG00000204632.11			8061	0.359	0.2855	Yes
58	ISOC1	ENSG00000066583.12			8741	0.346	0.2740	Yes
59	MARCH1	ENSG00000145416.13			8766	0.345	0.2785	Yes
60	IL4R	ENSG00000077238.14			8901	0.339	0.2802	Yes
61	IFI27	ENSG00000165949.12			8989	0.336	0.2831	Yes
62	AC124319.1	ENSG00000262979.1			9005	0.335	0.2876	Yes
63	ISG15	ENSG00000187608.10			9081	0.332	0.2907	Yes
64	MX2	ENSG00000183486.13			9117	0.330	0.2947	Yes
65	XCL1	ENSG00000143184.5			9258	0.325	0.2961	Yes
66	TAP1	ENSG00000168394.11			9314	0.323	0.2995	Yes
67	IRF1	ENSG00000125347.14			9828	0.318	0.2917	Yes
68	CCL5	ENSG00000271503.6			9843	0.317	0.2960	Yes
69	ICAM1	ENSG00000090339.9			9924	0.314	0.2987	Yes
70	VCAM1	ENSG00000162692.12			9928	0.314	0.3032	Yes
71	CD74	ENSG00000019582.15			9998	0.311	0.3061	Yes
72	PARP14	ENSG00000173193.15			10063	0.309	0.3091	Yes
73	ZBP1	ENSG00000124256.15			10602	0.305	0.3005	No
74	MYD88	ENSG00000172936.14			10743	0.301	0.3015	No
75	UBE2L6	ENSG00000156587.16			11121	0.287	0.2965	No
76	ARID5B	ENSG00000150347.16			11745	0.281	0.2855	No
77	IFI35	ENSG00000068079.7			11935	0.274	0.2849	No
78	PLSCR1	ENSG00000188313.13			12014	0.270	0.2870	No
79	ST3GAL5	ENSG00000115525.18			12059	0.269	0.2899	No
80	PARP12	ENSG00000059378.12			12149	0.266	0.2916	No
81	SOCS3	ENSG00000184557.4			12172	0.265	0.2950	No
82	CSF2RB	ENSG00000100368.14			12216	0.264	0.2978	No
83	LY6E	ENSG00000160932.11			12542	0.253	0.2936	No
84	BATF2	ENSG00000168062.10			12564	0.253	0.2968	No
85	IFI44	ENSG00000137965.11			12802	0.244	0.2946	No
86	IL15RA	ENSG00000134470.21			12907	0.241	0.2956	No
87	STAT2	ENSG00000170581.14			13299	0.229	0.2895	No
88	SAMHD1	ENSG00000101347.9			13779	0.214	0.2809	No
89	CD40	ENSG00000101017.14			13803	0.213	0.2835	No
90	CASP4	ENSG00000196954.14			13818	0.213	0.2863	No
91	PSMB8	ENSG00000204264.11			14058	0.204	0.2835	No
92	TNFAIP6	ENSG00000123610.5			14070	0.204	0.2862	No
93	TRIM21	ENSG00000132109.10			14145	0.201	0.2874	No
94	CCL2	ENSG00000108691.9			14738	0.183	0.2756	No
95	OGFR	ENSG00000060491.16			15086	0.171	0.2696	No
96	GBP6	ENSG00000183347.14			15114	0.170	0.2715	No
97	ITGB7	ENSG00000139626.16			15259	0.166	0.2704	No
98	CASP1	ENSG00000137752.24			15477	0.160	0.2675	No
99	APOL6	ENSG00000221963.6			15593	0.157	0.2670	No
100	PTPN2	ENSG00000175354.20			15648	0.155	0.2679	No
101	IFIT3	ENSG00000119917.14			16281	0.138	0.2545	No
102	CXCL9	ENSG00000138755.6			16417	0.133	0.2532	No
103	IL7	ENSG00000104432.14			16729	0.124	0.2475	No
104	DDX58	ENSG00000107201.10			16873	0.121	0.2457	No
105	ADAR	ENSG00000160710.17			16918	0.119	0.2464	No
106	IFIT1	ENSG00000185745.10			17150	0.113	0.2425	No
107	IFITM3	ENSG00000142089.16			17463	0.105	0.2364	No
108	SERPING1	ENSG00000149131.15			17821	0.096	0.2291	No
109	PIM1	ENSG00000137193.14			18349	0.082	0.2174	No
110	IFIT2	ENSG00000119922.10			18440	0.081	0.2164	No
111	AUTS2	ENSG00000158321.18			18675	0.074	0.2118	No
112	NFKB1	ENSG00000109320.13			19218	0.059	0.1994	No
113	JAK2	ENSG00000096968.13			19235	0.058	0.1999	No
114	PSME2	ENSG00000100911.16			19274	0.057	0.1998	No
115	ST8SIA4	ENSG00000113532.13			19279	0.057	0.2006	No
116	PSMA3	ENSG00000100567.13			19401	0.054	0.1984	No
117	PSMA2	ENSG00000106588.11			19562	0.050	0.1952	No
118	SP110	ENSG00000135899.17			19587	0.049	0.1954	No
119	SLC25A28	ENSG00000155287.11			19742	0.045	0.1923	No
120	PSMB10	ENSG00000205220.12			19937	0.040	0.1881	No
121	CMTR1	ENSG00000137200.13			20027	0.039	0.1865	No
122	RBCK1	ENSG00000125826.20			20153	0.035	0.1840	No
123	IRF2	ENSG00000168310.11			20158	0.035	0.1844	No
124	CXCL11	ENSG00000169248.13			20828	0.017	0.1683	No
125	PTPN6	ENSG00000111679.17			20832	0.017	0.1685	No
126	IFNAR2	ENSG00000159110.19			20879	0.015	0.1676	No
127	RIPK2	ENSG00000104312.8			21192	0.007	0.1601	No
128	CDKN1A	ENSG00000124762.13			21297	0.004	0.1576	No
129	SOD2	ENSG00000112096.18			21731	-0.007	0.1472	No
130	P2RY14	ENSG00000174944.9			22378	-0.023	0.1317	No
131	EIF2AK2	ENSG00000055332.18			22459	-0.025	0.1301	No
132	TRIM25	ENSG00000121060.18			22590	-0.028	0.1274	No
133	NFKBIA	ENSG00000100906.10			22848	-0.035	0.1216	No
134	B2M	ENSG00000166710.20			22947	-0.038	0.1198	No
135	PSME1	ENSG00000092010.15			23061	-0.041	0.1176	No
136	PSMB9	ENSG00000240065.8			23347	-0.048	0.1114	No
137	EIF4E3	ENSG00000163412.13			24006	-0.065	0.0963	No
138	PML	ENSG00000140464.20			24111	-0.067	0.0947	No
139	SRI	ENSG00000075142.13			24123	-0.067	0.0954	No
140	RIPK1	ENSG00000137275.14			24330	-0.074	0.0915	No
141	CASP7	ENSG00000165806.20			24757	-0.084	0.0824	No
142	PNPT1	ENSG00000138035.15			25366	-0.101	0.0690	No
143	PTPN1	ENSG00000196396.10			25434	-0.103	0.0689	No
144	MTHFD2	ENSG00000065911.12			25466	-0.104	0.0697	No
145	IFITM2	ENSG00000185201.16			25478	-0.105	0.0709	No
146	CD274	ENSG00000120217.14			25534	-0.106	0.0712	No
147	BST2	ENSG00000130303.13			26105	-0.124	0.0591	No
148	SAMD9L	ENSG00000177409.12			26142	-0.124	0.0600	No
149	KLRK1	ENSG00000213809.9			26215	-0.126	0.0601	No
150	PSMB2	ENSG00000126067.12			26219	-0.126	0.0619	No
151	SLAMF7	ENSG00000026751.17			26224	-0.126	0.0637	No
152	TRIM14	ENSG00000106785.15			26324	-0.129	0.0632	No
153	TAPBP	ENSG00000231925.11			26413	-0.133	0.0630	No
154	SOCS1	ENSG00000185338.5			26705	-0.141	0.0580	No
155	TNFAIP3	ENSG00000118503.15			27043	-0.151	0.0520	No
156	NMI	ENSG00000123609.11			27198	-0.155	0.0505	No
157	TRIM26	ENSG00000234127.9			27466	-0.163	0.0464	No
158	MVP	ENSG00000013364.19			28173	-0.185	0.0319	No
159	TRAFD1	ENSG00000135148.12			28382	-0.192	0.0296	No
160	WARS	ENSG00000140105.18			28765	-0.204	0.0233	No
161	HLA-DRB1	ENSG00000196126.11			28911	-0.209	0.0228	No
162	BPGM	ENSG00000172331.12			29104	-0.215	0.0213	No
163	HIF1A	ENSG00000100644.17			29230	-0.218	0.0215	No
164	IL6	ENSG00000136244.12			29624	-0.231	0.0153	No
165	CASP8	ENSG00000064012.21			30481	-0.259	-0.0018	No
166	STAT1	ENSG00000115415.18			30631	-0.263	-0.0015	No
167	LAP3	ENSG00000002549.12			30778	-0.269	-0.0011	No
168	NUP93	ENSG00000102900.13			32074	-0.299	-0.0283	No
169	FGL2	ENSG00000127951.7			32655	-0.323	-0.0377	No
170	CXCL10	ENSG00000169245.6			32700	-0.324	-0.0340	No
171	TOR1B	ENSG00000136816.16			33530	-0.337	-0.0493	No
172	FAS	ENSG00000026103.22			34075	-0.344	-0.0575	No
173	LGALS3BP	ENSG00000108679.13			34698	-0.356	-0.0675	No
174	STAT4	ENSG00000138378.19			34796	-0.361	-0.0645	No
175	CASP3	ENSG00000164305.19			35329	-0.380	-0.0719	No
176	PFKP	ENSG00000067057.17			35494	-0.388	-0.0702	No
177	CD86	ENSG00000114013.16			35887	-0.402	-0.0738	No
178	PNP	ENSG00000198805.11			36135	-0.411	-0.0738	No
179	FPR1	ENSG00000171051.8			36312	-0.416	-0.0719	No
180	ZNFX1	ENSG00000124201.15			36725	-0.437	-0.0756	No
181	SPPL2A	ENSG00000138600.10			36760	-0.438	-0.0699	No
182	VAMP8	ENSG00000118640.11			36910	-0.447	-0.0670	No
183	GBP4	ENSG00000162654.9			37113	-0.458	-0.0652	No
184	HLA-DMA	ENSG00000204257.15			37225	-0.465	-0.0610	No
185	SSPN	ENSG00000123096.11			37348	-0.474	-0.0570	No
186	TDRD7	ENSG00000196116.8			38973	-0.598	-0.0878	No
187	SELP	ENSG00000174175.17			39143	-0.614	-0.0829	No
188	IFI30	ENSG00000216490.4			39276	-0.621	-0.0770	No
189	TXNIP	ENSG00000265972.6			39777	-0.670	-0.0793	No
190	ARL4A	ENSG00000122644.13			40051	-0.722	-0.0753	No
191	VAMP5	ENSG00000168899.5			40113	-0.734	-0.0660	No
192	LYSMD2	ENSG00000140280.14			40171	-0.746	-0.0564	No
193	LATS2	ENSG00000150457.9			40697	-0.923	-0.0556	No
194	IL10RA	ENSG00000110324.10			40784	-0.953	-0.0437	No
195	IL15	ENSG00000164136.17			41012	-1.156	-0.0322	No
196	CD69	ENSG00000110848.8			41040	-1.206	-0.0151	No
197	NCOA3	ENSG00000124151.19			41048	-1.221	0.0028	No

Fig 2: HALLMARK_INTERFERON_GAMMA_RESPONSE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_INTERFERON_GAMMA_RESPONSE: Random ES distribution   
Gene set null distribution of ES for HALLMARK_INTERFERON_GAMMA_RESPONSE