Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | HALLMARK_MYC_TARGETS_V1 |
| Enrichment Score (ES) | -0.5283177 |
| Normalized Enrichment Score (NES) | -2.8118408 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PRPS2 | ENSG00000101911.12 | 7190 | 0.381 | -0.1679 | No | ||
| 2 | U2AF1 | ENSG00000160201.11 | 9311 | 0.323 | -0.2132 | No | ||
| 3 | NHP2 | ENSG00000145912.8 | 11929 | 0.274 | -0.2716 | No | ||
| 4 | IFRD1 | ENSG00000006652.14 | 13167 | 0.233 | -0.2972 | No | ||
| 5 | PRPF31 | ENSG00000105618.14 | 13506 | 0.221 | -0.3010 | No | ||
| 6 | RNPS1 | ENSG00000205937.12 | 15515 | 0.159 | -0.3469 | No | ||
| 7 | SNRPA1 | ENSG00000131876.17 | 15707 | 0.153 | -0.3485 | No | ||
| 8 | CNBP | ENSG00000169714.16 | 16602 | 0.128 | -0.3677 | No | ||
| 9 | PHB2 | ENSG00000215021.9 | 16837 | 0.122 | -0.3710 | No | ||
| 10 | FBL | ENSG00000105202.9 | 17026 | 0.117 | -0.3733 | No | ||
| 11 | RPL18 | ENSG00000063177.13 | 17257 | 0.110 | -0.3767 | No | ||
| 12 | MCM7 | ENSG00000166508.17 | 17495 | 0.104 | -0.3804 | No | ||
| 13 | EIF4A1 | ENSG00000161960.15 | 17708 | 0.099 | -0.3836 | No | ||
| 14 | RPS10 | ENSG00000124614.16 | 18756 | 0.072 | -0.4077 | No | ||
| 15 | TRIM28 | ENSG00000130726.12 | 19136 | 0.061 | -0.4157 | No | ||
| 16 | PSMA2 | ENSG00000106588.11 | 19562 | 0.050 | -0.4251 | No | ||
| 17 | ORC2 | ENSG00000115942.9 | 19607 | 0.048 | -0.4252 | No | ||
| 18 | RPS5 | ENSG00000083845.9 | 19611 | 0.048 | -0.4243 | No | ||
| 19 | LSM7 | ENSG00000130332.15 | 19871 | 0.041 | -0.4298 | No | ||
| 20 | RPS3 | ENSG00000149273.15 | 20169 | 0.035 | -0.4364 | No | ||
| 21 | NPM1 | ENSG00000181163.13 | 20296 | 0.031 | -0.4388 | No | ||
| 22 | APEX1 | ENSG00000100823.12 | 20345 | 0.030 | -0.4394 | No | ||
| 23 | NOLC1 | ENSG00000166197.16 | 20493 | 0.025 | -0.4425 | No | ||
| 24 | MRPL9 | ENSG00000143436.11 | 20794 | 0.018 | -0.4495 | No | ||
| 25 | PSMC4 | ENSG00000013275.8 | 20810 | 0.018 | -0.4495 | No | ||
| 26 | PSMA6 | ENSG00000100902.11 | 20976 | 0.013 | -0.4533 | No | ||
| 27 | RRP9 | ENSG00000114767.7 | 21079 | 0.009 | -0.4556 | No | ||
| 28 | SF3A1 | ENSG00000099995.19 | 21396 | 0.001 | -0.4633 | No | ||
| 29 | STARD7 | ENSG00000084090.13 | 21499 | -0.001 | -0.4657 | No | ||
| 30 | ILF2 | ENSG00000143621.17 | 21631 | -0.005 | -0.4688 | No | ||
| 31 | MRPL23 | ENSG00000214026.11 | 21654 | -0.005 | -0.4693 | No | ||
| 32 | NAP1L1 | ENSG00000187109.14 | 22158 | -0.017 | -0.4812 | No | ||
| 33 | CAD | ENSG00000084774.14 | 22254 | -0.020 | -0.4831 | No | ||
| 34 | HNRNPD | ENSG00000138668.19 | 22348 | -0.022 | -0.4850 | No | ||
| 35 | RACK1 | ENSG00000204628.12 | 22465 | -0.026 | -0.4873 | No | ||
| 36 | TRA2B | ENSG00000136527.18 | 22499 | -0.027 | -0.4876 | No | ||
| 37 | CBX3 | ENSG00000122565.19 | 22650 | -0.030 | -0.4906 | No | ||
| 38 | RPS6 | ENSG00000137154.13 | 22762 | -0.032 | -0.4927 | No | ||
| 39 | PSMD3 | ENSG00000108344.15 | 23004 | -0.040 | -0.4978 | No | ||
| 40 | SNRPA | ENSG00000077312.9 | 23189 | -0.045 | -0.5014 | No | ||
| 41 | PSMA1 | ENSG00000129084.17 | 23337 | -0.048 | -0.5040 | No | ||
| 42 | SF3B3 | ENSG00000189091.13 | 23382 | -0.049 | -0.5041 | No | ||
| 43 | POLE3 | ENSG00000148229.13 | 23456 | -0.051 | -0.5049 | No | ||
| 44 | TARDBP | ENSG00000120948.17 | 23539 | -0.054 | -0.5058 | No | ||
| 45 | COPS5 | ENSG00000121022.14 | 23597 | -0.055 | -0.5061 | No | ||
| 46 | EIF4H | ENSG00000106682.14 | 23982 | -0.064 | -0.5142 | No | ||
| 47 | RPS2 | ENSG00000140988.16 | 23996 | -0.064 | -0.5132 | No | ||
| 48 | IMPDH2 | ENSG00000178035.12 | 24066 | -0.066 | -0.5136 | No | ||
| 49 | SNRPD2 | ENSG00000125743.10 | 24100 | -0.067 | -0.5131 | No | ||
| 50 | EEF1B2 | ENSG00000114942.14 | 24117 | -0.067 | -0.5121 | No | ||
| 51 | RPL34 | ENSG00000109475.16 | 24170 | -0.069 | -0.5120 | No | ||
| 52 | SMARCC1 | ENSG00000173473.11 | 24189 | -0.069 | -0.5111 | No | ||
| 53 | LSM2 | ENSG00000204392.11 | 24207 | -0.070 | -0.5101 | No | ||
| 54 | RPLP0 | ENSG00000089157.16 | 24300 | -0.073 | -0.5109 | No | ||
| 55 | ACP1 | ENSG00000143727.16 | 24324 | -0.074 | -0.5099 | No | ||
| 56 | CANX | ENSG00000127022.15 | 24334 | -0.074 | -0.5087 | No | ||
| 57 | GOT2 | ENSG00000125166.13 | 24356 | -0.075 | -0.5077 | No | ||
| 58 | CYC1 | ENSG00000179091.5 | 24456 | -0.076 | -0.5086 | No | ||
| 59 | GNL3 | ENSG00000163938.17 | 24468 | -0.076 | -0.5073 | No | ||
| 60 | CUL1 | ENSG00000055130.17 | 24550 | -0.079 | -0.5078 | No | ||
| 61 | HNRNPA3 | ENSG00000170144.20 | 24564 | -0.079 | -0.5065 | No | ||
| 62 | RPL14 | ENSG00000188846.14 | 24854 | -0.087 | -0.5118 | No | ||
| 63 | MRPS18B | ENSG00000204568.12 | 24957 | -0.090 | -0.5125 | No | ||
| 64 | PABPC4 | ENSG00000090621.14 | 25191 | -0.096 | -0.5163 | No | ||
| 65 | RPL22 | ENSG00000116251.11 | 25247 | -0.097 | -0.5157 | No | ||
| 66 | SRM | ENSG00000116649.10 | 25409 | -0.102 | -0.5175 | No | ||
| 67 | KARS | ENSG00000065427.14 | 25576 | -0.107 | -0.5195 | No | ||
| 68 | TUFM | ENSG00000178952.11 | 25612 | -0.109 | -0.5181 | No | ||
| 69 | PSMD8 | ENSG00000099341.11 | 25815 | -0.114 | -0.5208 | No | ||
| 70 | SLC25A3 | ENSG00000075415.12 | 25831 | -0.115 | -0.5189 | No | ||
| 71 | PSMB2 | ENSG00000126067.12 | 26219 | -0.126 | -0.5258 | Yes | ||
| 72 | CDK4 | ENSG00000135446.17 | 26296 | -0.129 | -0.5251 | Yes | ||
| 73 | PCBP1 | ENSG00000169564.7 | 26427 | -0.133 | -0.5256 | Yes | ||
| 74 | PSMA7 | ENSG00000101182.15 | 26454 | -0.134 | -0.5236 | Yes | ||
| 75 | XRCC6 | ENSG00000196419.12 | 26529 | -0.136 | -0.5226 | Yes | ||
| 76 | HNRNPA2B1 | ENSG00000122566.21 | 26574 | -0.137 | -0.5210 | Yes | ||
| 77 | SNRPG | ENSG00000143977.14 | 26784 | -0.143 | -0.5232 | Yes | ||
| 78 | HNRNPA1 | ENSG00000135486.17 | 26807 | -0.144 | -0.5209 | Yes | ||
| 79 | PABPC1 | ENSG00000070756.16 | 26850 | -0.145 | -0.5190 | Yes | ||
| 80 | ERH | ENSG00000100632.11 | 27029 | -0.150 | -0.5204 | Yes | ||
| 81 | USP1 | ENSG00000162607.13 | 27180 | -0.154 | -0.5209 | Yes | ||
| 82 | EIF3D | ENSG00000100353.18 | 27222 | -0.156 | -0.5188 | Yes | ||
| 83 | DUT | ENSG00000128951.14 | 27355 | -0.160 | -0.5189 | Yes | ||
| 84 | SRSF7 | ENSG00000115875.19 | 27401 | -0.161 | -0.5168 | Yes | ||
| 85 | CLNS1A | ENSG00000074201.9 | 27442 | -0.162 | -0.5145 | Yes | ||
| 86 | DHX15 | ENSG00000109606.13 | 27469 | -0.163 | -0.5119 | Yes | ||
| 87 | NOP56 | ENSG00000101361.17 | 27506 | -0.165 | -0.5095 | Yes | ||
| 88 | TOMM70 | ENSG00000154174.8 | 27507 | -0.165 | -0.5062 | Yes | ||
| 89 | EIF3B | ENSG00000106263.18 | 27538 | -0.166 | -0.5036 | Yes | ||
| 90 | HNRNPU | ENSG00000153187.20 | 27597 | -0.167 | -0.5017 | Yes | ||
| 91 | HDGF | ENSG00000143321.19 | 27609 | -0.168 | -0.4986 | Yes | ||
| 92 | HNRNPC | ENSG00000092199.17 | 27651 | -0.169 | -0.4962 | Yes | ||
| 93 | SNRPB2 | ENSG00000125870.11 | 27668 | -0.170 | -0.4932 | Yes | ||
| 94 | DDX18 | ENSG00000088205.13 | 27696 | -0.170 | -0.4905 | Yes | ||
| 95 | NCBP2 | ENSG00000114503.11 | 27882 | -0.176 | -0.4915 | Yes | ||
| 96 | SET | ENSG00000119335.16 | 27902 | -0.177 | -0.4884 | Yes | ||
| 97 | PSMB3 | ENSG00000277791.5 | 27956 | -0.179 | -0.4861 | Yes | ||
| 98 | HDDC2 | ENSG00000111906.18 | 28202 | -0.186 | -0.4884 | Yes | ||
| 99 | RSL1D1 | ENSG00000171490.13 | 28400 | -0.193 | -0.4893 | Yes | ||
| 100 | HNRNPR | ENSG00000125944.20 | 28434 | -0.194 | -0.4863 | Yes | ||
| 101 | PSMC6 | ENSG00000100519.12 | 28449 | -0.195 | -0.4827 | Yes | ||
| 102 | CCT7 | ENSG00000135624.16 | 28576 | -0.199 | -0.4818 | Yes | ||
| 103 | SNRPD3 | ENSG00000100028.12 | 28579 | -0.199 | -0.4779 | Yes | ||
| 104 | RUVBL2 | ENSG00000183207.14 | 28623 | -0.200 | -0.4750 | Yes | ||
| 105 | PPM1G | ENSG00000115241.11 | 28760 | -0.204 | -0.4742 | Yes | ||
| 106 | HSP90AB1 | ENSG00000096384.20 | 28800 | -0.205 | -0.4711 | Yes | ||
| 107 | UBA2 | ENSG00000126261.13 | 28812 | -0.206 | -0.4672 | Yes | ||
| 108 | CCT4 | ENSG00000115484.15 | 28919 | -0.209 | -0.4656 | Yes | ||
| 109 | HDAC2 | ENSG00000196591.12 | 29075 | -0.214 | -0.4651 | Yes | ||
| 110 | SRSF2 | ENSG00000161547.16 | 29115 | -0.215 | -0.4618 | Yes | ||
| 111 | G3BP1 | ENSG00000145907.15 | 29198 | -0.217 | -0.4595 | Yes | ||
| 112 | IARS | ENSG00000196305.17 | 29268 | -0.220 | -0.4567 | Yes | ||
| 113 | ETF1 | ENSG00000120705.13 | 29337 | -0.222 | -0.4540 | Yes | ||
| 114 | NOP16 | ENSG00000048162.20 | 29405 | -0.225 | -0.4511 | Yes | ||
| 115 | CSTF2 | ENSG00000101811.13 | 29735 | -0.236 | -0.4544 | Yes | ||
| 116 | POLD2 | ENSG00000106628.10 | 29968 | -0.243 | -0.4552 | Yes | ||
| 117 | PSMD7 | ENSG00000103035.11 | 30001 | -0.244 | -0.4512 | Yes | ||
| 118 | SERBP1 | ENSG00000142864.14 | 30049 | -0.246 | -0.4474 | Yes | ||
| 119 | PSMA4 | ENSG00000041357.16 | 30107 | -0.247 | -0.4438 | Yes | ||
| 120 | PTGES3 | ENSG00000110958.16 | 30197 | -0.250 | -0.4410 | Yes | ||
| 121 | EIF3J | ENSG00000104131.13 | 30550 | -0.261 | -0.4444 | Yes | ||
| 122 | RFC4 | ENSG00000163918.10 | 30672 | -0.265 | -0.4421 | Yes | ||
| 123 | RANBP1 | ENSG00000099901.17 | 30689 | -0.265 | -0.4372 | Yes | ||
| 124 | YWHAQ | ENSG00000134308.14 | 30852 | -0.271 | -0.4357 | Yes | ||
| 125 | EIF4G2 | ENSG00000110321.17 | 30886 | -0.273 | -0.4310 | Yes | ||
| 126 | XPOT | ENSG00000184575.12 | 30889 | -0.273 | -0.4256 | Yes | ||
| 127 | NDUFAB1 | ENSG00000004779.10 | 31179 | -0.284 | -0.4270 | Yes | ||
| 128 | FAM120A | ENSG00000048828.17 | 31716 | -0.286 | -0.4344 | Yes | ||
| 129 | SRSF3 | ENSG00000112081.17 | 31790 | -0.289 | -0.4304 | Yes | ||
| 130 | TXNL4A | ENSG00000141759.15 | 31802 | -0.290 | -0.4249 | Yes | ||
| 131 | PA2G4 | ENSG00000170515.14 | 31890 | -0.293 | -0.4211 | Yes | ||
| 132 | SYNCRIP | ENSG00000135316.18 | 31926 | -0.294 | -0.4161 | Yes | ||
| 133 | KPNB1 | ENSG00000108424.10 | 31990 | -0.296 | -0.4118 | Yes | ||
| 134 | BUB3 | ENSG00000154473.18 | 32087 | -0.300 | -0.4081 | Yes | ||
| 135 | NCBP1 | ENSG00000136937.13 | 32105 | -0.301 | -0.4025 | Yes | ||
| 136 | CDK2 | ENSG00000123374.11 | 32246 | -0.307 | -0.3998 | Yes | ||
| 137 | MCM2 | ENSG00000073111.14 | 32546 | -0.318 | -0.4008 | Yes | ||
| 138 | SSBP1 | ENSG00000106028.11 | 32684 | -0.323 | -0.3976 | Yes | ||
| 139 | PWP1 | ENSG00000136045.12 | 32864 | -0.330 | -0.3954 | Yes | ||
| 140 | ODC1 | ENSG00000115758.13 | 32958 | -0.334 | -0.3910 | Yes | ||
| 141 | EIF2S2 | ENSG00000125977.7 | 32987 | -0.335 | -0.3850 | Yes | ||
| 142 | VDAC3 | ENSG00000078668.14 | 32993 | -0.336 | -0.3784 | Yes | ||
| 143 | SSB | ENSG00000138385.16 | 34149 | -0.347 | -0.3997 | Yes | ||
| 144 | CDC20 | ENSG00000117399.14 | 34187 | -0.349 | -0.3936 | Yes | ||
| 145 | HSPD1 | ENSG00000144381.17 | 34204 | -0.350 | -0.3870 | Yes | ||
| 146 | SRSF1 | ENSG00000136450.13 | 34211 | -0.350 | -0.3802 | Yes | ||
| 147 | CCT2 | ENSG00000166226.13 | 34576 | -0.350 | -0.3820 | Yes | ||
| 148 | C1QBP | ENSG00000108561.8 | 34663 | -0.355 | -0.3771 | Yes | ||
| 149 | MCM6 | ENSG00000076003.5 | 34728 | -0.357 | -0.3715 | Yes | ||
| 150 | SNRPD1 | ENSG00000167088.11 | 34734 | -0.358 | -0.3645 | Yes | ||
| 151 | GLO1 | ENSG00000124767.7 | 34770 | -0.359 | -0.3581 | Yes | ||
| 152 | H2AFZ | ENSG00000164032.12 | 35129 | -0.370 | -0.3595 | Yes | ||
| 153 | RRM1 | ENSG00000167325.15 | 35147 | -0.371 | -0.3525 | Yes | ||
| 154 | COX5A | ENSG00000178741.12 | 35154 | -0.371 | -0.3452 | Yes | ||
| 155 | UBE2L3 | ENSG00000185651.14 | 35300 | -0.378 | -0.3412 | Yes | ||
| 156 | TFDP1 | ENSG00000198176.13 | 35512 | -0.389 | -0.3386 | Yes | ||
| 157 | CCT5 | ENSG00000150753.12 | 35533 | -0.390 | -0.3313 | Yes | ||
| 158 | PHB | ENSG00000167085.11 | 35649 | -0.396 | -0.3262 | Yes | ||
| 159 | TCP1 | ENSG00000120438.12 | 35702 | -0.397 | -0.3195 | Yes | ||
| 160 | MCM5 | ENSG00000100297.16 | 35805 | -0.402 | -0.3139 | Yes | ||
| 161 | HSPE1 | ENSG00000115541.11 | 35951 | -0.403 | -0.3094 | Yes | ||
| 162 | EPRS | ENSG00000136628.18 | 36119 | -0.410 | -0.3053 | Yes | ||
| 163 | SRPK1 | ENSG00000096063.16 | 36129 | -0.411 | -0.2973 | Yes | ||
| 164 | CTPS1 | ENSG00000171793.16 | 36239 | -0.413 | -0.2917 | Yes | ||
| 165 | AP3S1 | ENSG00000177879.16 | 36282 | -0.415 | -0.2845 | Yes | ||
| 166 | PSMD14 | ENSG00000115233.12 | 36419 | -0.422 | -0.2794 | Yes | ||
| 167 | YWHAE | ENSG00000108953.17 | 36492 | -0.426 | -0.2726 | Yes | ||
| 168 | RAN | ENSG00000132341.12 | 36507 | -0.427 | -0.2644 | Yes | ||
| 169 | ABCE1 | ENSG00000164163.11 | 36773 | -0.438 | -0.2621 | Yes | ||
| 170 | HPRT1 | ENSG00000165704.15 | 36862 | -0.444 | -0.2554 | Yes | ||
| 171 | EXOSC7 | ENSG00000075914.13 | 37003 | -0.452 | -0.2498 | Yes | ||
| 172 | CCT3 | ENSG00000163468.15 | 37023 | -0.454 | -0.2412 | Yes | ||
| 173 | PPIA | ENSG00000196262.14 | 37055 | -0.456 | -0.2329 | Yes | ||
| 174 | VDAC1 | ENSG00000213585.11 | 37080 | -0.457 | -0.2243 | Yes | ||
| 175 | PCNA | ENSG00000132646.11 | 37166 | -0.461 | -0.2172 | Yes | ||
| 176 | XPO1 | ENSG00000082898.17 | 37227 | -0.465 | -0.2094 | Yes | ||
| 177 | UBE2E1 | ENSG00000170142.12 | 37384 | -0.477 | -0.2036 | Yes | ||
| 178 | PRDX4 | ENSG00000123131.13 | 37599 | -0.493 | -0.1990 | Yes | ||
| 179 | VBP1 | ENSG00000155959.12 | 37620 | -0.495 | -0.1896 | Yes | ||
| 180 | PSMD1 | ENSG00000173692.13 | 37725 | -0.504 | -0.1821 | Yes | ||
| 181 | PGK1 | ENSG00000102144.15 | 37804 | -0.512 | -0.1737 | Yes | ||
| 182 | MAD2L1 | ENSG00000164109.14 | 37893 | -0.520 | -0.1655 | Yes | ||
| 183 | DEK | ENSG00000124795.17 | 37896 | -0.520 | -0.1552 | Yes | ||
| 184 | NME1 | ENSG00000239672.7 | 38038 | -0.530 | -0.1480 | Yes | ||
| 185 | EIF4E | ENSG00000151247.12 | 38303 | -0.552 | -0.1434 | Yes | ||
| 186 | EIF2S1 | ENSG00000134001.13 | 38693 | -0.570 | -0.1415 | Yes | ||
| 187 | AIMP2 | ENSG00000106305.10 | 38805 | -0.581 | -0.1326 | Yes | ||
| 188 | CDC45 | ENSG00000093009.10 | 38822 | -0.583 | -0.1214 | Yes | ||
| 189 | MYC | ENSG00000136997.19 | 39003 | -0.602 | -0.1138 | Yes | ||
| 190 | DDX21 | ENSG00000165732.13 | 39636 | -0.651 | -0.1162 | Yes | ||
| 191 | GSPT1 | ENSG00000103342.13 | 39655 | -0.655 | -0.1035 | Yes | ||
| 192 | PRDX3 | ENSG00000165672.7 | 40078 | -0.727 | -0.0993 | Yes | ||
| 193 | EIF1AX | ENSG00000173674.11 | 40168 | -0.746 | -0.0866 | Yes | ||
| 194 | MCM4 | ENSG00000104738.18 | 40591 | -0.872 | -0.0795 | Yes | ||
| 195 | CCNA2 | ENSG00000145386.10 | 40598 | -0.874 | -0.0622 | Yes | ||
| 196 | TYMS | ENSG00000176890.16 | 40602 | -0.877 | -0.0447 | Yes | ||
| 197 | KPNA2 | ENSG00000182481.9 | 40625 | -0.887 | -0.0275 | Yes | ||
| 198 | LDHA | ENSG00000134333.14 | 40682 | -0.914 | -0.0107 | Yes | ||
| 199 | RAD23B | ENSG00000119318.13 | 40986 | -1.117 | 0.0043 | Yes |
