Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.40761572 |
| Normalized Enrichment Score (NES) | -2.1639023 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ATP6V0C | ENSG00000185883.12 | 1864 | 0.723 | -0.0299 | No | ||
| 2 | BCKDHA | ENSG00000248098.12 | 2582 | 0.645 | -0.0335 | No | ||
| 3 | TCIRG1 | ENSG00000110719.10 | 3281 | 0.585 | -0.0379 | No | ||
| 4 | NDUFA7 | ENSG00000267855.6 | 3809 | 0.549 | -0.0390 | No | ||
| 5 | BDH2 | ENSG00000164039.15 | 5094 | 0.484 | -0.0599 | No | ||
| 6 | POR | ENSG00000127948.16 | 6799 | 0.396 | -0.0929 | No | ||
| 7 | NDUFS7 | ENSG00000115286.20 | 7135 | 0.383 | -0.0929 | No | ||
| 8 | NDUFV1 | ENSG00000167792.13 | 9086 | 0.332 | -0.1333 | No | ||
| 9 | RHOT2 | ENSG00000140983.14 | 9334 | 0.322 | -0.1324 | No | ||
| 10 | ATP6V0B | ENSG00000117410.14 | 10913 | 0.294 | -0.1646 | No | ||
| 11 | MTRF1 | ENSG00000120662.16 | 11953 | 0.273 | -0.1841 | No | ||
| 12 | PDK4 | ENSG00000004799.8 | 12277 | 0.262 | -0.1863 | No | ||
| 13 | ACADVL | ENSG00000072778.20 | 14036 | 0.205 | -0.2248 | No | ||
| 14 | TIMM10 | ENSG00000134809.9 | 14734 | 0.183 | -0.2379 | No | ||
| 15 | IDH3B | ENSG00000101365.21 | 15051 | 0.172 | -0.2419 | No | ||
| 16 | ISCA1 | ENSG00000135070.15 | 15172 | 0.169 | -0.2412 | No | ||
| 17 | GPX4 | ENSG00000167468.17 | 15215 | 0.168 | -0.2386 | No | ||
| 18 | COX11 | ENSG00000166260.11 | 15554 | 0.158 | -0.2434 | No | ||
| 19 | ABCB7 | ENSG00000131269.19 | 16228 | 0.139 | -0.2569 | No | ||
| 20 | SDHA | ENSG00000073578.17 | 16659 | 0.127 | -0.2646 | No | ||
| 21 | PHB2 | ENSG00000215021.9 | 16837 | 0.122 | -0.2663 | No | ||
| 22 | COX4I1 | ENSG00000131143.9 | 16849 | 0.121 | -0.2640 | No | ||
| 23 | MRPS30 | ENSG00000112996.11 | 16953 | 0.118 | -0.2640 | No | ||
| 24 | NDUFA3 | ENSG00000170906.16 | 17714 | 0.099 | -0.2804 | No | ||
| 25 | ATP5F1D | ENSG00000099624.8 | 17733 | 0.098 | -0.2787 | No | ||
| 26 | MRPS12 | ENSG00000128626.11 | 17737 | 0.098 | -0.2767 | No | ||
| 27 | ACADM | ENSG00000117054.13 | 17744 | 0.098 | -0.2747 | No | ||
| 28 | TIMM13 | ENSG00000099800.8 | 17899 | 0.093 | -0.2764 | No | ||
| 29 | POLR2F | ENSG00000100142.15 | 18001 | 0.091 | -0.2770 | No | ||
| 30 | PMPCA | ENSG00000165688.12 | 18125 | 0.087 | -0.2781 | No | ||
| 31 | NDUFS3 | ENSG00000213619.10 | 18514 | 0.078 | -0.2859 | No | ||
| 32 | IDH3G | ENSG00000067829.19 | 18543 | 0.078 | -0.2849 | No | ||
| 33 | ISCU | ENSG00000136003.15 | 18869 | 0.069 | -0.2913 | No | ||
| 34 | ECI1 | ENSG00000167969.13 | 18931 | 0.067 | -0.2914 | No | ||
| 35 | NDUFB5 | ENSG00000136521.13 | 19104 | 0.062 | -0.2942 | No | ||
| 36 | OXA1L | ENSG00000155463.14 | 19265 | 0.058 | -0.2969 | No | ||
| 37 | ECH1 | ENSG00000104823.9 | 19400 | 0.054 | -0.2990 | No | ||
| 38 | DECR1 | ENSG00000104325.7 | 19432 | 0.053 | -0.2986 | No | ||
| 39 | PDHX | ENSG00000110435.12 | 19637 | 0.048 | -0.3026 | No | ||
| 40 | NDUFB4 | ENSG00000065518.8 | 19809 | 0.043 | -0.3058 | No | ||
| 41 | MRPL11 | ENSG00000174547.13 | 20071 | 0.038 | -0.3114 | No | ||
| 42 | SURF1 | ENSG00000148290.10 | 20388 | 0.028 | -0.3185 | No | ||
| 43 | COX5B | ENSG00000135940.7 | 20725 | 0.019 | -0.3263 | No | ||
| 44 | MAOB | ENSG00000069535.14 | 21045 | 0.010 | -0.3338 | No | ||
| 45 | NDUFC2 | ENSG00000151366.13 | 21512 | -0.001 | -0.3452 | No | ||
| 46 | ACO2 | ENSG00000100412.16 | 21529 | -0.002 | -0.3455 | No | ||
| 47 | MRPS15 | ENSG00000116898.12 | 21640 | -0.005 | -0.3481 | No | ||
| 48 | NDUFV2 | ENSG00000178127.13 | 21692 | -0.006 | -0.3492 | No | ||
| 49 | MRPL34 | ENSG00000130312.6 | 21791 | -0.009 | -0.3514 | No | ||
| 50 | COX7C | ENSG00000127184.13 | 22188 | -0.018 | -0.3607 | No | ||
| 51 | ATP5MC2 | ENSG00000135390.20 | 22194 | -0.018 | -0.3604 | No | ||
| 52 | MRPS11 | ENSG00000181991.16 | 22309 | -0.021 | -0.3628 | No | ||
| 53 | NDUFS8 | ENSG00000110717.13 | 22354 | -0.022 | -0.3634 | No | ||
| 54 | ATP6V1F | ENSG00000128524.5 | 22492 | -0.026 | -0.3661 | No | ||
| 55 | ACAA1 | ENSG00000060971.18 | 22593 | -0.028 | -0.3680 | No | ||
| 56 | NDUFB7 | ENSG00000099795.7 | 22725 | -0.031 | -0.3705 | No | ||
| 57 | NDUFA9 | ENSG00000139180.11 | 22799 | -0.033 | -0.3716 | No | ||
| 58 | IDH1 | ENSG00000138413.13 | 22996 | -0.039 | -0.3755 | No | ||
| 59 | ALAS1 | ENSG00000023330.15 | 23130 | -0.043 | -0.3778 | No | ||
| 60 | TIMM50 | ENSG00000105197.11 | 23134 | -0.043 | -0.3770 | No | ||
| 61 | GPI | ENSG00000105220.17 | 23611 | -0.056 | -0.3874 | No | ||
| 62 | SLC25A11 | ENSG00000108528.14 | 23697 | -0.058 | -0.3882 | No | ||
| 63 | NDUFA6 | ENSG00000184983.11 | 23744 | -0.059 | -0.3881 | No | ||
| 64 | MRPS22 | ENSG00000175110.11 | 24058 | -0.066 | -0.3943 | No | ||
| 65 | NDUFS2 | ENSG00000158864.12 | 24199 | -0.070 | -0.3962 | No | ||
| 66 | LRPPRC | ENSG00000138095.19 | 24323 | -0.074 | -0.3976 | No | ||
| 67 | GOT2 | ENSG00000125166.13 | 24356 | -0.075 | -0.3968 | No | ||
| 68 | CYC1 | ENSG00000179091.5 | 24456 | -0.076 | -0.3976 | No | ||
| 69 | ATP6V1G1 | ENSG00000136888.7 | 24614 | -0.080 | -0.3997 | No | ||
| 70 | NDUFS6 | ENSG00000145494.11 | 24650 | -0.081 | -0.3988 | No | ||
| 71 | NDUFB6 | ENSG00000165264.11 | 24651 | -0.081 | -0.3970 | No | ||
| 72 | FH | ENSG00000091483.6 | 24742 | -0.084 | -0.3974 | No | ||
| 73 | CASP7 | ENSG00000165806.20 | 24757 | -0.084 | -0.3959 | No | ||
| 74 | NDUFA2 | ENSG00000131495.8 | 24820 | -0.086 | -0.3956 | No | ||
| 75 | NDUFC1 | ENSG00000109390.12 | 25125 | -0.094 | -0.4010 | No | ||
| 76 | UQCRB | ENSG00000156467.9 | 25298 | -0.099 | -0.4030 | No | ||
| 77 | MFN2 | ENSG00000116688.16 | 25413 | -0.103 | -0.4036 | No | ||
| 78 | NDUFA1 | ENSG00000125356.7 | 25494 | -0.105 | -0.4033 | No | ||
| 79 | CYB5A | ENSG00000166347.19 | 25515 | -0.106 | -0.4015 | No | ||
| 80 | RETSAT | ENSG00000042445.14 | 25766 | -0.113 | -0.4052 | Yes | ||
| 81 | PDHA1 | ENSG00000131828.14 | 25806 | -0.114 | -0.4037 | Yes | ||
| 82 | COX6A1 | ENSG00000111775.3 | 25808 | -0.114 | -0.4013 | Yes | ||
| 83 | SLC25A3 | ENSG00000075415.12 | 25831 | -0.115 | -0.3993 | Yes | ||
| 84 | MPC1 | ENSG00000060762.19 | 25930 | -0.118 | -0.3992 | Yes | ||
| 85 | UQCRC1 | ENSG00000010256.11 | 26010 | -0.121 | -0.3985 | Yes | ||
| 86 | DLST | ENSG00000119689.15 | 26173 | -0.125 | -0.3998 | Yes | ||
| 87 | UQCRFS1 | ENSG00000169021.6 | 26350 | -0.131 | -0.4012 | Yes | ||
| 88 | AIFM1 | ENSG00000156709.14 | 26439 | -0.133 | -0.4005 | Yes | ||
| 89 | ALDH6A1 | ENSG00000119711.13 | 26620 | -0.138 | -0.4019 | Yes | ||
| 90 | ACAA2 | ENSG00000167315.18 | 26626 | -0.139 | -0.3991 | Yes | ||
| 91 | NDUFB8 | ENSG00000166136.16 | 26636 | -0.139 | -0.3963 | Yes | ||
| 92 | HSD17B10 | ENSG00000072506.12 | 26721 | -0.141 | -0.3953 | Yes | ||
| 93 | LDHB | ENSG00000111716.13 | 26739 | -0.142 | -0.3926 | Yes | ||
| 94 | ATP5PF | ENSG00000154723.12 | 26834 | -0.144 | -0.3918 | Yes | ||
| 95 | UQCR11 | ENSG00000127540.12 | 26991 | -0.149 | -0.3924 | Yes | ||
| 96 | UQCRH | ENSG00000173660.12 | 27160 | -0.154 | -0.3932 | Yes | ||
| 97 | ATP6AP1 | ENSG00000071553.17 | 27324 | -0.159 | -0.3938 | Yes | ||
| 98 | NDUFB2 | ENSG00000090266.13 | 27438 | -0.162 | -0.3930 | Yes | ||
| 99 | COX7B | ENSG00000131174.7 | 27456 | -0.163 | -0.3899 | Yes | ||
| 100 | TOMM70 | ENSG00000154174.8 | 27507 | -0.165 | -0.3876 | Yes | ||
| 101 | SDHB | ENSG00000117118.9 | 27519 | -0.165 | -0.3843 | Yes | ||
| 102 | NQO2 | ENSG00000124588.20 | 27556 | -0.166 | -0.3816 | Yes | ||
| 103 | ECHS1 | ENSG00000127884.5 | 27650 | -0.169 | -0.3802 | Yes | ||
| 104 | COX8A | ENSG00000176340.4 | 27783 | -0.173 | -0.3797 | Yes | ||
| 105 | ACADSB | ENSG00000196177.12 | 27795 | -0.174 | -0.3762 | Yes | ||
| 106 | SDHD | ENSG00000204370.12 | 27840 | -0.175 | -0.3735 | Yes | ||
| 107 | PHYH | ENSG00000107537.14 | 27848 | -0.175 | -0.3699 | Yes | ||
| 108 | COX6B1 | ENSG00000126267.11 | 27937 | -0.178 | -0.3683 | Yes | ||
| 109 | TOMM22 | ENSG00000100216.6 | 27993 | -0.180 | -0.3657 | Yes | ||
| 110 | ATP5PO | ENSG00000241837.7 | 28230 | -0.187 | -0.3674 | Yes | ||
| 111 | HTRA2 | ENSG00000115317.11 | 28297 | -0.189 | -0.3650 | Yes | ||
| 112 | ATP6V1C1 | ENSG00000155097.12 | 28302 | -0.190 | -0.3610 | Yes | ||
| 113 | NDUFB1 | ENSG00000183648.10 | 28308 | -0.190 | -0.3570 | Yes | ||
| 114 | ETFB | ENSG00000105379.9 | 28464 | -0.195 | -0.3566 | Yes | ||
| 115 | SUCLG1 | ENSG00000163541.12 | 28603 | -0.199 | -0.3557 | Yes | ||
| 116 | TIMM9 | ENSG00000100575.14 | 28631 | -0.200 | -0.3520 | Yes | ||
| 117 | BAX | ENSG00000087088.20 | 28685 | -0.202 | -0.3489 | Yes | ||
| 118 | MDH2 | ENSG00000146701.12 | 28720 | -0.203 | -0.3454 | Yes | ||
| 119 | NDUFS1 | ENSG00000023228.14 | 28739 | -0.203 | -0.3415 | Yes | ||
| 120 | COX15 | ENSG00000014919.12 | 28798 | -0.205 | -0.3385 | Yes | ||
| 121 | ATP5MC3 | ENSG00000154518.9 | 28805 | -0.205 | -0.3342 | Yes | ||
| 122 | ATP5MG | ENSG00000167283.8 | 28977 | -0.211 | -0.3338 | Yes | ||
| 123 | FDX1 | ENSG00000137714.3 | 29012 | -0.212 | -0.3300 | Yes | ||
| 124 | UQCR10 | ENSG00000184076.13 | 29240 | -0.219 | -0.3309 | Yes | ||
| 125 | NDUFB3 | ENSG00000119013.9 | 29266 | -0.220 | -0.3267 | Yes | ||
| 126 | COX7A2 | ENSG00000112695.11 | 29269 | -0.220 | -0.3220 | Yes | ||
| 127 | UQCRQ | ENSG00000164405.11 | 29432 | -0.226 | -0.3211 | Yes | ||
| 128 | UQCRC2 | ENSG00000140740.11 | 29691 | -0.234 | -0.3224 | Yes | ||
| 129 | TIMM8B | ENSG00000150779.12 | 29908 | -0.241 | -0.3225 | Yes | ||
| 130 | PDP1 | ENSG00000164951.16 | 30013 | -0.244 | -0.3197 | Yes | ||
| 131 | IDH3A | ENSG00000166411.14 | 30386 | -0.256 | -0.3233 | Yes | ||
| 132 | NDUFA8 | ENSG00000119421.7 | 30403 | -0.257 | -0.3181 | Yes | ||
| 133 | MRPL35 | ENSG00000132313.15 | 30453 | -0.258 | -0.3138 | Yes | ||
| 134 | COX10 | ENSG00000006695.12 | 30599 | -0.263 | -0.3116 | Yes | ||
| 135 | ATP5F1B | ENSG00000110955.9 | 30702 | -0.266 | -0.3084 | Yes | ||
| 136 | PDHB | ENSG00000168291.13 | 30731 | -0.267 | -0.3033 | Yes | ||
| 137 | ETFDH | ENSG00000171503.12 | 30873 | -0.272 | -0.3009 | Yes | ||
| 138 | VDAC2 | ENSG00000165637.13 | 31005 | -0.277 | -0.2981 | Yes | ||
| 139 | MTRR | ENSG00000124275.15 | 31028 | -0.278 | -0.2927 | Yes | ||
| 140 | NDUFAB1 | ENSG00000004779.10 | 31179 | -0.284 | -0.2902 | Yes | ||
| 141 | GLUD1 | ENSG00000148672.9 | 31751 | -0.287 | -0.2980 | Yes | ||
| 142 | COX7A2L | ENSG00000115944.15 | 31768 | -0.288 | -0.2921 | Yes | ||
| 143 | ATP5F1A | ENSG00000152234.16 | 31775 | -0.288 | -0.2861 | Yes | ||
| 144 | SLC25A5 | ENSG00000005022.6 | 31924 | -0.294 | -0.2833 | Yes | ||
| 145 | SUCLA2 | ENSG00000136143.16 | 32023 | -0.297 | -0.2793 | Yes | ||
| 146 | ATP5ME | ENSG00000169020.10 | 32116 | -0.301 | -0.2751 | Yes | ||
| 147 | NDUFA5 | ENSG00000128609.15 | 32180 | -0.303 | -0.2701 | Yes | ||
| 148 | HADHB | ENSG00000138029.14 | 32206 | -0.305 | -0.2641 | Yes | ||
| 149 | ATP5PB | ENSG00000116459.11 | 32284 | -0.308 | -0.2593 | Yes | ||
| 150 | SLC25A4 | ENSG00000151729.11 | 32397 | -0.314 | -0.2553 | Yes | ||
| 151 | NNT | ENSG00000112992.18 | 32480 | -0.316 | -0.2505 | Yes | ||
| 152 | SLC25A12 | ENSG00000115840.14 | 32611 | -0.321 | -0.2468 | Yes | ||
| 153 | ATP6V0E1 | ENSG00000113732.9 | 32622 | -0.321 | -0.2401 | Yes | ||
| 154 | COX6C | ENSG00000164919.11 | 32702 | -0.324 | -0.2350 | Yes | ||
| 155 | SDHC | ENSG00000143252.14 | 32711 | -0.324 | -0.2282 | Yes | ||
| 156 | GRPEL1 | ENSG00000109519.13 | 32886 | -0.331 | -0.2253 | Yes | ||
| 157 | CS | ENSG00000062485.19 | 32933 | -0.333 | -0.2193 | Yes | ||
| 158 | VDAC3 | ENSG00000078668.14 | 32993 | -0.336 | -0.2135 | Yes | ||
| 159 | AFG3L2 | ENSG00000141385.9 | 32997 | -0.336 | -0.2063 | Yes | ||
| 160 | SUPV3L1 | ENSG00000156502.14 | 33532 | -0.337 | -0.2121 | Yes | ||
| 161 | ATP5PD | ENSG00000167863.12 | 33549 | -0.338 | -0.2052 | Yes | ||
| 162 | IMMT | ENSG00000132305.20 | 33557 | -0.338 | -0.1981 | Yes | ||
| 163 | MRPL15 | ENSG00000137547.9 | 34174 | -0.348 | -0.2056 | Yes | ||
| 164 | HCCS | ENSG00000004961.15 | 34647 | -0.354 | -0.2095 | Yes | ||
| 165 | HSPA9 | ENSG00000113013.15 | 34748 | -0.358 | -0.2042 | Yes | ||
| 166 | ATP6V1E1 | ENSG00000131100.13 | 34970 | -0.364 | -0.2018 | Yes | ||
| 167 | CPT1A | ENSG00000110090.13 | 35082 | -0.368 | -0.1965 | Yes | ||
| 168 | COX17 | ENSG00000138495.6 | 35127 | -0.370 | -0.1896 | Yes | ||
| 169 | COX5A | ENSG00000178741.12 | 35154 | -0.371 | -0.1823 | Yes | ||
| 170 | CYCS | ENSG00000172115.8 | 35191 | -0.373 | -0.1751 | Yes | ||
| 171 | HADHA | ENSG00000084754.12 | 35261 | -0.376 | -0.1687 | Yes | ||
| 172 | OPA1 | ENSG00000198836.10 | 35274 | -0.377 | -0.1608 | Yes | ||
| 173 | ATP6V1H | ENSG00000047249.18 | 35368 | -0.382 | -0.1549 | Yes | ||
| 174 | ATP5MC1 | ENSG00000159199.14 | 35409 | -0.384 | -0.1476 | Yes | ||
| 175 | ATP6V1D | ENSG00000100554.12 | 35460 | -0.386 | -0.1405 | Yes | ||
| 176 | RHOT1 | ENSG00000126858.18 | 35588 | -0.393 | -0.1351 | Yes | ||
| 177 | ATP5MF | ENSG00000241468.7 | 35793 | -0.402 | -0.1314 | Yes | ||
| 178 | ETFA | ENSG00000140374.16 | 36284 | -0.415 | -0.1344 | Yes | ||
| 179 | CYB5R3 | ENSG00000100243.21 | 36413 | -0.421 | -0.1284 | Yes | ||
| 180 | NDUFA4 | ENSG00000189043.10 | 36425 | -0.422 | -0.1196 | Yes | ||
| 181 | NDUFS4 | ENSG00000164258.12 | 36704 | -0.436 | -0.1170 | Yes | ||
| 182 | MDH1 | ENSG00000014641.19 | 36811 | -0.441 | -0.1101 | Yes | ||
| 183 | OAT | ENSG00000065154.11 | 36957 | -0.449 | -0.1039 | Yes | ||
| 184 | VDAC1 | ENSG00000213585.11 | 37080 | -0.457 | -0.0971 | Yes | ||
| 185 | DLAT | ENSG00000150768.15 | 37266 | -0.468 | -0.0915 | Yes | ||
| 186 | FXN | ENSG00000165060.14 | 37346 | -0.474 | -0.0832 | Yes | ||
| 187 | ATP5F1C | ENSG00000165629.20 | 37540 | -0.488 | -0.0774 | Yes | ||
| 188 | ATP5F1E | ENSG00000124172.10 | 37604 | -0.494 | -0.0683 | Yes | ||
| 189 | DLD | ENSG00000091140.14 | 37792 | -0.512 | -0.0618 | Yes | ||
| 190 | SLC25A20 | ENSG00000178537.10 | 37913 | -0.521 | -0.0535 | Yes | ||
| 191 | MTX2 | ENSG00000128654.14 | 38114 | -0.536 | -0.0468 | Yes | ||
| 192 | MGST3 | ENSG00000143198.13 | 38656 | -0.567 | -0.0478 | Yes | ||
| 193 | IDH2 | ENSG00000182054.9 | 38704 | -0.571 | -0.0367 | Yes | ||
| 194 | TIMM17A | ENSG00000134375.11 | 38838 | -0.584 | -0.0273 | Yes | ||
| 195 | OGDH | ENSG00000105953.15 | 39008 | -0.602 | -0.0185 | Yes | ||
| 196 | PRDX3 | ENSG00000165672.7 | 40078 | -0.727 | -0.0289 | Yes | ||
| 197 | ACAT1 | ENSG00000075239.14 | 40127 | -0.737 | -0.0142 | Yes | ||
| 198 | ATP1B1 | ENSG00000143153.13 | 40677 | -0.912 | -0.0079 | Yes | ||
| 199 | LDHA | ENSG00000134333.14 | 40682 | -0.914 | 0.0117 | Yes |
