Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | -0.24862324 |
| Normalized Enrichment Score (NES) | -1.0503522 |
| Nominal p-value | 0.36153847 |
| FDR q-value | 0.40021053 |
| FWER p-Value | 0.998 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LSP1 | ENSG00000130592.15 | 2548 | 0.649 | -0.0240 | No | ||
| 2 | EGLN2 | ENSG00000269858.6 | 2577 | 0.646 | 0.0131 | No | ||
| 3 | PRDX2 | ENSG00000167815.12 | 2763 | 0.627 | 0.0453 | No | ||
| 4 | FES | ENSG00000182511.12 | 5088 | 0.484 | 0.0172 | No | ||
| 5 | ABCC1 | ENSG00000103222.19 | 5110 | 0.483 | 0.0449 | No | ||
| 6 | NQO1 | ENSG00000181019.13 | 6107 | 0.428 | 0.0458 | No | ||
| 7 | G6PD | ENSG00000160211.19 | 6110 | 0.428 | 0.0708 | No | ||
| 8 | SBNO2 | ENSG00000064932.16 | 6373 | 0.414 | 0.0886 | No | ||
| 9 | HHEX | ENSG00000152804.11 | 6564 | 0.405 | 0.1077 | No | ||
| 10 | MSRA | ENSG00000175806.15 | 7544 | 0.369 | 0.1055 | No | ||
| 11 | GCLC | ENSG00000001084.13 | 7671 | 0.364 | 0.1238 | No | ||
| 12 | TXNRD1 | ENSG00000198431.16 | 7984 | 0.362 | 0.1374 | No | ||
| 13 | JUNB | ENSG00000171223.6 | 8148 | 0.355 | 0.1542 | No | ||
| 14 | CAT | ENSG00000121691.7 | 8736 | 0.346 | 0.1602 | No | ||
| 15 | FTL | ENSG00000087086.15 | 9008 | 0.335 | 0.1732 | No | ||
| 16 | MGST1 | ENSG00000008394.13 | 12207 | 0.264 | 0.1109 | No | ||
| 17 | GPX4 | ENSG00000167468.17 | 15215 | 0.168 | 0.0476 | No | ||
| 18 | GPX3 | ENSG00000211445.12 | 18462 | 0.080 | -0.0267 | No | ||
| 19 | NDUFB4 | ENSG00000065518.8 | 19809 | 0.043 | -0.0569 | No | ||
| 20 | SOD2 | ENSG00000112096.18 | 21731 | -0.007 | -0.1032 | No | ||
| 21 | GLRX | ENSG00000173221.14 | 23563 | -0.054 | -0.1446 | No | ||
| 22 | NDUFA6 | ENSG00000184983.11 | 23744 | -0.059 | -0.1455 | No | ||
| 23 | SRXN1 | ENSG00000271303.1 | 23769 | -0.059 | -0.1426 | No | ||
| 24 | NDUFS2 | ENSG00000158864.12 | 24199 | -0.070 | -0.1490 | No | ||
| 25 | PTPA | ENSG00000119383.19 | 25019 | -0.092 | -0.1635 | No | ||
| 26 | SCAF4 | ENSG00000156304.15 | 25257 | -0.098 | -0.1636 | No | ||
| 27 | IPCEF1 | ENSG00000074706.13 | 25881 | -0.116 | -0.1719 | No | ||
| 28 | SELENOS | ENSG00000131871.15 | 28063 | -0.183 | -0.2142 | No | ||
| 29 | GSR | ENSG00000104687.14 | 28212 | -0.187 | -0.2069 | No | ||
| 30 | PRNP | ENSG00000171867.17 | 28702 | -0.202 | -0.2070 | No | ||
| 31 | GLRX2 | ENSG00000023572.9 | 28880 | -0.208 | -0.1991 | No | ||
| 32 | STK25 | ENSG00000115694.15 | 28992 | -0.212 | -0.1894 | No | ||
| 33 | TXN | ENSG00000136810.13 | 29623 | -0.231 | -0.1912 | No | ||
| 34 | GCLM | ENSG00000023909.10 | 29935 | -0.242 | -0.1846 | No | ||
| 35 | HMOX2 | ENSG00000103415.12 | 31936 | -0.294 | -0.2160 | No | ||
| 36 | SOD1 | ENSG00000142168.14 | 32307 | -0.310 | -0.2069 | No | ||
| 37 | LAMTOR5 | ENSG00000134248.13 | 32894 | -0.332 | -0.2017 | No | ||
| 38 | TXNRD2 | ENSG00000184470.21 | 34824 | -0.362 | -0.2274 | Yes | ||
| 39 | PFKP | ENSG00000067057.17 | 35494 | -0.388 | -0.2210 | Yes | ||
| 40 | PRDX1 | ENSG00000117450.14 | 36141 | -0.411 | -0.2126 | Yes | ||
| 41 | PRDX4 | ENSG00000123131.13 | 37599 | -0.493 | -0.2192 | Yes | ||
| 42 | OXSR1 | ENSG00000172939.9 | 38012 | -0.528 | -0.1983 | Yes | ||
| 43 | ATOX1 | ENSG00000177556.12 | 38206 | -0.543 | -0.1712 | Yes | ||
| 44 | PRDX6 | ENSG00000117592.9 | 38289 | -0.550 | -0.1409 | Yes | ||
| 45 | PDLIM1 | ENSG00000107438.9 | 38736 | -0.574 | -0.1182 | Yes | ||
| 46 | MPO | ENSG00000005381.8 | 39785 | -0.671 | -0.1044 | Yes | ||
| 47 | CDKN2D | ENSG00000129355.7 | 40158 | -0.743 | -0.0699 | Yes | ||
| 48 | ERCC2 | ENSG00000104884.15 | 40308 | -0.779 | -0.0279 | Yes | ||
| 49 | MBP | ENSG00000197971.15 | 40474 | -0.830 | 0.0167 | Yes |
