Details for gene set HALLMARK_SPERMATOGENESIS[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	ARH
GeneSet	HALLMARK_SPERMATOGENESIS
Enrichment Score (ES)	-0.25144485
Normalized Enrichment Score (NES)	-1.2339151
Nominal p-value	0.07861635
FDR q-value	0.14174718
FWER p-Value	0.773

Fig 1: Enrichment plot: HALLMARK_SPERMATOGENESIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ALOX15	ENSG00000161905.12			287	1.141	0.0223	No
2	CHRM4	ENSG00000180720.7			496	1.017	0.0434	No
3	YBX2	ENSG00000006047.13			836	0.902	0.0583	No
4	ADCYAP1	ENSG00000141433.13			1245	0.810	0.0692	No
5	ART3	ENSG00000156219.16			1870	0.721	0.0725	No
6	MEP1B	ENSG00000141434.12			3162	0.594	0.0563	No
7	SPATA6	ENSG00000132122.12			3326	0.582	0.0673	No
8	DCC	ENSG00000187323.12			3653	0.561	0.0738	No
9	PCSK4	ENSG00000115257.15			4245	0.528	0.0729	No
10	HTR5A	ENSG00000157219.5			4461	0.518	0.0810	No
11	CLGN	ENSG00000153132.13			4537	0.516	0.0925	No
12	IL12RB2	ENSG00000081985.11			4762	0.507	0.1000	No
13	PCSK1N	ENSG00000102109.9			5202	0.477	0.1016	No
14	POMC	ENSG00000115138.11			5463	0.461	0.1071	No
15	DDX4	ENSG00000152670.19			6193	0.423	0.1002	No
16	LDHC	ENSG00000166796.12			8497	0.351	0.0531	No
17	PGS1	ENSG00000087157.19			8520	0.350	0.0616	No
18	AKAP4	ENSG00000147081.15			9429	0.319	0.0477	No
19	SYCP1	ENSG00000198765.12			9452	0.319	0.0554	No
20	LPIN1	ENSG00000134324.11			10847	0.297	0.0290	No
21	DDX25	ENSG00000109832.14			10932	0.293	0.0345	No
22	HOXB1	ENSG00000120094.9			11100	0.287	0.0378	No
23	GAPDHS	ENSG00000105679.9			11950	0.273	0.0241	No
24	MAST2	ENSG00000086015.21			11962	0.272	0.0309	No
25	ZC2HC1C	ENSG00000119703.14			12497	0.255	0.0244	No
26	TEKT2	ENSG00000092850.12			12955	0.239	0.0194	No
27	CHFR	ENSG00000072609.17			14676	0.185	-0.0177	No
28	ACTL7B	ENSG00000148156.8			15954	0.146	-0.0451	No
29	ELOVL3	ENSG00000119915.5			16089	0.143	-0.0447	No
30	NPHP1	ENSG00000144061.12			16101	0.142	-0.0413	No
31	GAD1	ENSG00000128683.14			16125	0.142	-0.0382	No
32	GRM8	ENSG00000179603.17			16235	0.139	-0.0373	No
33	ACE	ENSG00000159640.16			16370	0.135	-0.0371	No
34	TULP2	ENSG00000104804.8			16450	0.132	-0.0356	No
35	IP6K1	ENSG00000176095.12			16499	0.131	-0.0335	No
36	HSPA2	ENSG00000126803.9			16949	0.118	-0.0414	No
37	PACRG	ENSG00000112530.11			17068	0.116	-0.0413	No
38	PGK2	ENSG00000170950.6			17549	0.102	-0.0503	No
39	ADAD1	ENSG00000164113.11			17699	0.099	-0.0514	No
40	CCNA1	ENSG00000133101.10			17734	0.098	-0.0497	No
41	TALDO1	ENSG00000177156.11			18425	0.081	-0.0644	No
42	CLPB	ENSG00000162129.14			18742	0.072	-0.0703	No
43	CLVS1	ENSG00000177182.11			18836	0.070	-0.0708	No
44	PHKG2	ENSG00000156873.16			18966	0.066	-0.0722	No
45	PAPOLB	ENSG00000218823.2			19127	0.062	-0.0745	No
46	CSNK2A2	ENSG00000070770.9			19164	0.061	-0.0738	No
47	DPEP3	ENSG00000141096.6			19167	0.061	-0.0723	No
48	PARP2	ENSG00000129484.13			19624	0.048	-0.0822	No
49	PDHA2	ENSG00000163114.6			21711	-0.006	-0.1329	No
50	SIRT1	ENSG00000096717.12			21793	-0.009	-0.1346	No
51	TNP2	ENSG00000178279.4			21864	-0.011	-0.1361	No
52	ACRBP	ENSG00000111644.8			22439	-0.025	-0.1494	No
53	AGFG1	ENSG00000173744.17			22700	-0.031	-0.1550	No
54	TOPBP1	ENSG00000163781.14			22850	-0.035	-0.1577	No
55	HSPA4L	ENSG00000164070.12			23282	-0.046	-0.1670	No
56	PHF7	ENSG00000010318.21			23590	-0.055	-0.1731	No
57	MTOR	ENSG00000198793.13			23734	-0.059	-0.1751	No
58	ZC3H14	ENSG00000100722.20			24498	-0.077	-0.1917	No
59	HBZ	ENSG00000130656.6			24610	-0.080	-0.1923	No
60	COIL	ENSG00000121058.5			24633	-0.081	-0.1908	No
61	GSTM3	ENSG00000134202.11			24806	-0.086	-0.1928	No
62	ODF1	ENSG00000155087.4			24987	-0.091	-0.1948	No
63	SCG3	ENSG00000104112.9			25353	-0.101	-0.2011	No
64	MAP7	ENSG00000135525.18			25553	-0.107	-0.2032	No
65	DBF4	ENSG00000006634.8			25980	-0.120	-0.2105	No
66	JAM3	ENSG00000166086.13			26245	-0.127	-0.2137	No
67	TLE4	ENSG00000106829.19			26262	-0.128	-0.2108	No
68	BRAF	ENSG00000157764.13			26610	-0.138	-0.2157	No
69	NOS1	ENSG00000089250.19			27089	-0.152	-0.2235	No
70	CFTR	ENSG00000001626.15			27772	-0.173	-0.2356	No
71	TUBA3C	ENSG00000198033.12			27829	-0.175	-0.2325	No
72	MLLT10	ENSG00000078403.17			27899	-0.176	-0.2297	No
73	HSPA1L	ENSG00000204390.10			27981	-0.180	-0.2270	No
74	PSMG1	ENSG00000183527.12			28095	-0.184	-0.2250	No
75	CAMK4	ENSG00000152495.11			28125	-0.184	-0.2210	No
76	SLC2A5	ENSG00000142583.18			29013	-0.212	-0.2372	No
77	HIST1H1T	ENSG00000187475.5			29600	-0.230	-0.2455	Yes
78	EZH2	ENSG00000106462.10			29613	-0.231	-0.2399	Yes
79	SNAP91	ENSG00000065609.14			29977	-0.243	-0.2425	Yes
80	PEBP1	ENSG00000089220.5			30027	-0.245	-0.2374	Yes
81	CDKN3	ENSG00000100526.20			30484	-0.259	-0.2418	Yes
82	IFT88	ENSG00000032742.17			30640	-0.264	-0.2388	Yes
83	RFC4	ENSG00000163918.10			30672	-0.265	-0.2328	Yes
84	GPR182	ENSG00000166856.3			30724	-0.267	-0.2272	Yes
85	TSN	ENSG00000211460.12			31004	-0.277	-0.2268	Yes
86	IL13RA2	ENSG00000123496.8			31074	-0.280	-0.2213	Yes
87	GSG1	ENSG00000111305.19			31123	-0.282	-0.2153	Yes
88	ACRV1	ENSG00000134940.14			31144	-0.283	-0.2085	Yes
89	NAA11	ENSG00000156269.5			31145	-0.283	-0.2012	Yes
90	GMCL1	ENSG00000087338.5			31165	-0.283	-0.1944	Yes
91	PIAS2	ENSG00000078043.16			32124	-0.301	-0.2100	Yes
92	THEG	ENSG00000105549.11			32498	-0.317	-0.2110	Yes
93	SHE	ENSG00000169291.10			32504	-0.317	-0.2029	Yes
94	RAD17	ENSG00000152942.19			32645	-0.322	-0.1981	Yes
95	VDAC3	ENSG00000078668.14			32993	-0.336	-0.1979	Yes
96	RPL39L	ENSG00000163923.10			34191	-0.349	-0.2181	Yes
97	TCP11	ENSG00000124678.18			34710	-0.356	-0.2216	Yes
98	STAM2	ENSG00000115145.10			34753	-0.359	-0.2134	Yes
99	SCG5	ENSG00000166922.8			35094	-0.368	-0.2122	Yes
100	STRBP	ENSG00000165209.19			35121	-0.370	-0.2033	Yes
101	NEFH	ENSG00000100285.10			35194	-0.374	-0.1955	Yes
102	PRKAR2A	ENSG00000114302.16			35272	-0.377	-0.1877	Yes
103	TKTL1	ENSG00000007350.17			36144	-0.411	-0.1983	Yes
104	CCNB2	ENSG00000157456.8			36613	-0.432	-0.1986	Yes
105	KIF2C	ENSG00000142945.13			36852	-0.443	-0.1931	Yes
106	CNIH2	ENSG00000174871.11			37049	-0.455	-0.1861	Yes
107	MTNR1A	ENSG00000168412.6			37417	-0.479	-0.1828	Yes
108	DMC1	ENSG00000100206.10			37480	-0.483	-0.1719	Yes
109	CCT6B	ENSG00000132141.14			37660	-0.499	-0.1634	Yes
110	BUB1	ENSG00000169679.15			37763	-0.508	-0.1528	Yes
111	SLC12A2	ENSG00000064651.14			37771	-0.510	-0.1399	Yes
112	NEK2	ENSG00000117650.13			37958	-0.525	-0.1310	Yes
113	NF2	ENSG00000186575.18			37996	-0.527	-0.1183	Yes
114	TTK	ENSG00000112742.10			38213	-0.544	-0.1096	Yes
115	DNAJB8	ENSG00000179407.3			38332	-0.555	-0.0982	Yes
116	AURKA	ENSG00000087586.17			38638	-0.565	-0.0911	Yes
117	NCAPH	ENSG00000121152.10			38902	-0.590	-0.0824	Yes
118	OAZ3	ENSG00000143450.16			39039	-0.605	-0.0701	Yes
119	CDK1	ENSG00000170312.16			39453	-0.632	-0.0640	Yes
120	IDE	ENSG00000119912.17			39758	-0.668	-0.0542	Yes
121	ARL4A	ENSG00000122644.13			40051	-0.722	-0.0428	Yes
122	GFI1	ENSG00000162676.12			40452	-0.825	-0.0313	Yes
123	MLF1	ENSG00000178053.19			40547	-0.856	-0.0116	Yes
124	TNNI3	ENSG00000129991.13			40911	-1.033	0.0061	Yes

Fig 2: HALLMARK_SPERMATOGENESIS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_SPERMATOGENESIS: Random ES distribution   
Gene set null distribution of ES for HALLMARK_SPERMATOGENESIS