Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | HALLMARK_UNFOLDED_PROTEIN_RESPONSE |
| Enrichment Score (ES) | -0.28006923 |
| Normalized Enrichment Score (NES) | -1.3839352 |
| Nominal p-value | 0.029940119 |
| FDR q-value | 0.05722558 |
| FWER p-Value | 0.382 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TSPYL2 | ENSG00000184205.14 | 988 | 0.860 | 0.0128 | No | ||
| 2 | DDIT4 | ENSG00000168209.5 | 4218 | 0.529 | -0.0432 | No | ||
| 3 | EIF2AK3 | ENSG00000172071.14 | 5777 | 0.444 | -0.0621 | No | ||
| 4 | ASNS | ENSG00000070669.17 | 7241 | 0.378 | -0.0816 | No | ||
| 5 | ARFGAP1 | ENSG00000101199.13 | 7678 | 0.364 | -0.0766 | No | ||
| 6 | CEBPB | ENSG00000172216.6 | 8012 | 0.361 | -0.0693 | No | ||
| 7 | CXXC1 | ENSG00000154832.14 | 10845 | 0.297 | -0.1256 | No | ||
| 8 | FUS | ENSG00000089280.18 | 11843 | 0.277 | -0.1380 | No | ||
| 9 | NHP2 | ENSG00000145912.8 | 11929 | 0.274 | -0.1283 | No | ||
| 10 | ERN1 | ENSG00000178607.16 | 12166 | 0.265 | -0.1227 | No | ||
| 11 | SRPRB | ENSG00000144867.12 | 13817 | 0.213 | -0.1538 | No | ||
| 12 | WFS1 | ENSG00000109501.13 | 14511 | 0.190 | -0.1626 | No | ||
| 13 | NFYA | ENSG00000001167.14 | 14558 | 0.188 | -0.1556 | No | ||
| 14 | CCL2 | ENSG00000108691.9 | 14738 | 0.183 | -0.1522 | No | ||
| 15 | EXOSC5 | ENSG00000077348.9 | 14756 | 0.182 | -0.1448 | No | ||
| 16 | VEGFA | ENSG00000112715.22 | 15227 | 0.167 | -0.1491 | No | ||
| 17 | AC092881.1 | ENSG00000279530.2 | 15670 | 0.154 | -0.1532 | No | ||
| 18 | CHAC1 | ENSG00000128965.13 | 15855 | 0.149 | -0.1513 | No | ||
| 19 | DNAJB9 | ENSG00000128590.5 | 15986 | 0.146 | -0.1483 | No | ||
| 20 | GEMIN4 | ENSG00000179409.11 | 16483 | 0.131 | -0.1547 | No | ||
| 21 | ZBTB17 | ENSG00000116809.11 | 16702 | 0.125 | -0.1547 | No | ||
| 22 | EDC4 | ENSG00000038358.15 | 16708 | 0.125 | -0.1494 | No | ||
| 23 | IFIT1 | ENSG00000185745.10 | 17150 | 0.113 | -0.1553 | No | ||
| 24 | DNAJA4 | ENSG00000140403.12 | 17651 | 0.100 | -0.1632 | No | ||
| 25 | EIF4A1 | ENSG00000161960.15 | 17708 | 0.099 | -0.1604 | No | ||
| 26 | WIPI1 | ENSG00000070540.13 | 17719 | 0.099 | -0.1564 | No | ||
| 27 | DCP2 | ENSG00000172795.16 | 18047 | 0.089 | -0.1605 | No | ||
| 28 | PDIA6 | ENSG00000143870.12 | 18375 | 0.082 | -0.1650 | No | ||
| 29 | SHC1 | ENSG00000160691.18 | 18728 | 0.073 | -0.1705 | No | ||
| 30 | EXOC2 | ENSG00000112685.14 | 19227 | 0.059 | -0.1801 | No | ||
| 31 | SRPRA | ENSG00000182934.12 | 19417 | 0.053 | -0.1824 | No | ||
| 32 | EEF2 | ENSG00000167658.16 | 19540 | 0.050 | -0.1832 | No | ||
| 33 | STC2 | ENSG00000113739.10 | 19602 | 0.048 | -0.1826 | No | ||
| 34 | EXOSC2 | ENSG00000130713.16 | 19694 | 0.046 | -0.1829 | No | ||
| 35 | HERPUD1 | ENSG00000051108.15 | 20085 | 0.037 | -0.1908 | No | ||
| 36 | PARN | ENSG00000140694.17 | 20157 | 0.035 | -0.1910 | No | ||
| 37 | EIF4A2 | ENSG00000156976.17 | 20197 | 0.034 | -0.1905 | No | ||
| 38 | SSR1 | ENSG00000124783.14 | 20209 | 0.034 | -0.1893 | No | ||
| 39 | NPM1 | ENSG00000181163.13 | 20296 | 0.031 | -0.1901 | No | ||
| 40 | NOLC1 | ENSG00000166197.16 | 20493 | 0.025 | -0.1938 | No | ||
| 41 | HYOU1 | ENSG00000149428.19 | 20784 | 0.018 | -0.2001 | No | ||
| 42 | RRP9 | ENSG00000114767.7 | 21079 | 0.009 | -0.2068 | No | ||
| 43 | NFYB | ENSG00000120837.8 | 21305 | 0.004 | -0.2121 | No | ||
| 44 | CEBPG | ENSG00000153879.9 | 21361 | 0.002 | -0.2134 | No | ||
| 45 | SLC30A5 | ENSG00000145740.19 | 21659 | -0.005 | -0.2204 | No | ||
| 46 | DCP1A | ENSG00000272886.6 | 22387 | -0.023 | -0.2371 | No | ||
| 47 | CNOT4 | ENSG00000080802.18 | 22420 | -0.024 | -0.2369 | No | ||
| 48 | EXOSC4 | ENSG00000178896.9 | 22461 | -0.026 | -0.2367 | No | ||
| 49 | KDELR3 | ENSG00000100196.11 | 22740 | -0.032 | -0.2422 | No | ||
| 50 | NABP1 | ENSG00000173559.13 | 22786 | -0.033 | -0.2418 | No | ||
| 51 | EXOSC10 | ENSG00000171824.14 | 22846 | -0.034 | -0.2418 | No | ||
| 52 | BANF1 | ENSG00000175334.8 | 22894 | -0.036 | -0.2414 | No | ||
| 53 | XBP1 | ENSG00000100219.16 | 22900 | -0.036 | -0.2400 | No | ||
| 54 | KHSRP | ENSG00000088247.17 | 23065 | -0.041 | -0.2422 | No | ||
| 55 | CNOT6 | ENSG00000113300.13 | 23657 | -0.057 | -0.2542 | No | ||
| 56 | SEC11A | ENSG00000140612.14 | 23787 | -0.060 | -0.2547 | No | ||
| 57 | YIF1A | ENSG00000174851.16 | 24447 | -0.076 | -0.2676 | No | ||
| 58 | PREB | ENSG00000138073.14 | 24574 | -0.079 | -0.2672 | No | ||
| 59 | EIF4EBP1 | ENSG00000187840.5 | 24936 | -0.090 | -0.2722 | No | ||
| 60 | PSAT1 | ENSG00000135069.14 | 25261 | -0.098 | -0.2759 | Yes | ||
| 61 | ATF4 | ENSG00000128272.14 | 25324 | -0.100 | -0.2731 | Yes | ||
| 62 | MTHFD2 | ENSG00000065911.12 | 25466 | -0.104 | -0.2721 | Yes | ||
| 63 | HSP90B1 | ENSG00000166598.15 | 25632 | -0.109 | -0.2714 | Yes | ||
| 64 | SLC7A5 | ENSG00000103257.9 | 25788 | -0.113 | -0.2704 | Yes | ||
| 65 | SPCS1 | ENSG00000114902.14 | 26059 | -0.123 | -0.2717 | Yes | ||
| 66 | POP4 | ENSG00000105171.10 | 26244 | -0.127 | -0.2707 | Yes | ||
| 67 | LSM4 | ENSG00000130520.10 | 26495 | -0.135 | -0.2710 | Yes | ||
| 68 | H2AFX | ENSG00000188486.3 | 26590 | -0.138 | -0.2674 | Yes | ||
| 69 | SLC1A4 | ENSG00000115902.11 | 26994 | -0.149 | -0.2709 | Yes | ||
| 70 | ATF3 | ENSG00000162772.17 | 27076 | -0.151 | -0.2663 | Yes | ||
| 71 | PAIP1 | ENSG00000172239.14 | 27448 | -0.162 | -0.2684 | Yes | ||
| 72 | NOP56 | ENSG00000101361.17 | 27506 | -0.165 | -0.2628 | Yes | ||
| 73 | EXOSC1 | ENSG00000171311.13 | 27570 | -0.167 | -0.2571 | Yes | ||
| 74 | GOSR2 | ENSG00000108433.16 | 27707 | -0.171 | -0.2531 | Yes | ||
| 75 | RPS14 | ENSG00000164587.13 | 27808 | -0.174 | -0.2481 | Yes | ||
| 76 | FKBP14 | ENSG00000106080.10 | 27884 | -0.176 | -0.2424 | Yes | ||
| 77 | NOP14 | ENSG00000087269.16 | 28181 | -0.186 | -0.2417 | Yes | ||
| 78 | IMP3 | ENSG00000177971.8 | 28333 | -0.190 | -0.2372 | Yes | ||
| 79 | ALDH18A1 | ENSG00000059573.9 | 28433 | -0.194 | -0.2313 | Yes | ||
| 80 | IGFBP1 | ENSG00000146678.10 | 28557 | -0.198 | -0.2258 | Yes | ||
| 81 | MTREX | ENSG00000039123.16 | 28594 | -0.199 | -0.2182 | Yes | ||
| 82 | TATDN2 | ENSG00000157014.11 | 28712 | -0.202 | -0.2123 | Yes | ||
| 83 | TARS | ENSG00000113407.13 | 28859 | -0.207 | -0.2070 | Yes | ||
| 84 | CALR | ENSG00000179218.13 | 28898 | -0.208 | -0.1990 | Yes | ||
| 85 | DNAJC3 | ENSG00000102580.15 | 29103 | -0.215 | -0.1948 | Yes | ||
| 86 | LSM1 | ENSG00000175324.10 | 29217 | -0.218 | -0.1882 | Yes | ||
| 87 | IARS | ENSG00000196305.17 | 29268 | -0.220 | -0.1800 | Yes | ||
| 88 | EDEM1 | ENSG00000134109.11 | 29697 | -0.234 | -0.1804 | Yes | ||
| 89 | CKS1B | ENSG00000173207.13 | 30473 | -0.259 | -0.1882 | Yes | ||
| 90 | ATP6V0D1 | ENSG00000159720.12 | 30474 | -0.259 | -0.1771 | Yes | ||
| 91 | BAG3 | ENSG00000151929.9 | 30706 | -0.266 | -0.1713 | Yes | ||
| 92 | XPOT | ENSG00000184575.12 | 30889 | -0.273 | -0.1640 | Yes | ||
| 93 | SEC31A | ENSG00000138674.17 | 31154 | -0.283 | -0.1583 | Yes | ||
| 94 | EIF4G1 | ENSG00000114867.20 | 31786 | -0.289 | -0.1613 | Yes | ||
| 95 | ERO1A | ENSG00000197930.13 | 31946 | -0.294 | -0.1526 | Yes | ||
| 96 | HSPA5 | ENSG00000044574.8 | 32282 | -0.308 | -0.1475 | Yes | ||
| 97 | SERP1 | ENSG00000120742.11 | 32659 | -0.323 | -0.1429 | Yes | ||
| 98 | EXOSC9 | ENSG00000123737.12 | 32717 | -0.325 | -0.1304 | Yes | ||
| 99 | ATF6 | ENSG00000118217.6 | 32787 | -0.327 | -0.1180 | Yes | ||
| 100 | DKC1 | ENSG00000130826.18 | 32829 | -0.329 | -0.1049 | Yes | ||
| 101 | HSPA9 | ENSG00000113013.15 | 34748 | -0.358 | -0.1363 | Yes | ||
| 102 | SDAD1 | ENSG00000198301.12 | 35222 | -0.375 | -0.1318 | Yes | ||
| 103 | YWHAZ | ENSG00000164924.18 | 35696 | -0.397 | -0.1263 | Yes | ||
| 104 | DCTN1 | ENSG00000204843.12 | 35697 | -0.397 | -0.1093 | Yes | ||
| 105 | TTC37 | ENSG00000198677.11 | 36765 | -0.438 | -0.1165 | Yes | ||
| 106 | EIF4A3 | ENSG00000141543.12 | 37474 | -0.483 | -0.1131 | Yes | ||
| 107 | EIF4E | ENSG00000151247.12 | 38303 | -0.552 | -0.1096 | Yes | ||
| 108 | DDX10 | ENSG00000178105.11 | 38527 | -0.559 | -0.0911 | Yes | ||
| 109 | EIF2S1 | ENSG00000134001.13 | 38693 | -0.570 | -0.0707 | Yes | ||
| 110 | PDIA5 | ENSG00000065485.20 | 39643 | -0.653 | -0.0658 | Yes | ||
| 111 | SPCS3 | ENSG00000129128.13 | 39807 | -0.676 | -0.0408 | Yes | ||
| 112 | TUBB2A | ENSG00000137267.6 | 40266 | -0.768 | -0.0191 | Yes | ||
| 113 | KIF5B | ENSG00000170759.11 | 40785 | -0.954 | 0.0092 | Yes |
