Details for gene set HALLMARK_UV_RESPONSE_DN[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	ARH
GeneSet	HALLMARK_UV_RESPONSE_DN
Enrichment Score (ES)	-0.47000104
Normalized Enrichment Score (NES)	-2.407154
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: HALLMARK_UV_RESPONSE_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	EFEMP1	ENSG00000115380.20			575	0.988	0.0060	No
2	KALRN	ENSG00000160145.15			1565	0.764	-0.0027	No
3	LPAR1	ENSG00000198121.13			1657	0.752	0.0104	No
4	LTBP1	ENSG00000049323.16			2175	0.686	0.0116	No
5	NFIB	ENSG00000147862.17			2853	0.618	0.0076	No
6	ICA1	ENSG00000003147.19			3140	0.596	0.0127	No
7	SYNJ2	ENSG00000078269.15			3893	0.545	0.0054	No
8	SLC22A18	ENSG00000110628.15			4190	0.531	0.0090	No
9	CDKN1B	ENSG00000111276.11			4380	0.521	0.0149	No
10	ABCC1	ENSG00000103222.19			5110	0.483	0.0069	No
11	PDGFRB	ENSG00000113721.14			6580	0.405	-0.0207	No
12	LDLR	ENSG00000130164.13			6959	0.391	-0.0220	No
13	PIK3R3	ENSG00000117461.15			7066	0.387	-0.0168	No
14	DBP	ENSG00000105516.11			7657	0.364	-0.0238	No
15	INSIG1	ENSG00000186480.13			8475	0.352	-0.0366	No
16	ID1	ENSG00000125968.9			8857	0.341	-0.0390	No
17	CELF2	ENSG00000048740.18			9223	0.326	-0.0413	No
18	IGF1R	ENSG00000140443.15			9322	0.322	-0.0371	No
19	BDNF	ENSG00000176697.19			11933	0.274	-0.0952	No
20	PRKAR2B	ENSG00000005249.13			12170	0.265	-0.0956	No
21	MTA1	ENSG00000182979.18			13050	0.236	-0.1122	No
22	RND3	ENSG00000115963.13			13657	0.217	-0.1226	No
23	RBPMS	ENSG00000157110.16			14352	0.196	-0.1356	No
24	PRKCE	ENSG00000171132.14			16141	0.141	-0.1763	No
25	IRS1	ENSG00000169047.5			16185	0.140	-0.1745	No
26	TENT4A	ENSG00000112941.14			16700	0.125	-0.1845	No
27	PTPRM	ENSG00000173482.16			16775	0.123	-0.1838	No
28	AL162171.1	ENSG00000258789.1			17248	0.111	-0.1931	No
29	ZMIZ1	ENSG00000108175.17			17570	0.102	-0.1989	No
30	ATP2B1	ENSG00000070961.15			17717	0.099	-0.2004	No
31	PTGFR	ENSG00000122420.10			18031	0.090	-0.2062	No
32	RUNX1	ENSG00000159216.18			18123	0.087	-0.2067	No
33	ADGRL2	ENSG00000117114.19			18723	0.073	-0.2198	No
34	NFKB1	ENSG00000109320.13			19218	0.059	-0.2307	No
35	DYRK1A	ENSG00000157540.21			19241	0.058	-0.2300	No
36	ITGB3	ENSG00000259207.7			19335	0.055	-0.2312	No
37	MAGI2	ENSG00000187391.21			19355	0.055	-0.2305	No
38	SYNE1	ENSG00000131018.24			19377	0.054	-0.2299	No
39	RGS4	ENSG00000117152.13			19418	0.053	-0.2298	No
40	PTEN	ENSG00000171862.11			19922	0.040	-0.2413	No
41	RXRA	ENSG00000186350.12			20264	0.032	-0.2489	No
42	YTHDC1	ENSG00000083896.12			20287	0.032	-0.2488	No
43	TFPI	ENSG00000003436.16			20290	0.032	-0.2483	No
44	CDON	ENSG00000064309.14			20593	0.023	-0.2552	No
45	WDR37	ENSG00000047056.16			20874	0.016	-0.2617	No
46	ATRN	ENSG00000088812.18			21050	0.010	-0.2657	No
47	PHF3	ENSG00000118482.11			21189	0.007	-0.2689	No
48	SFMBT1	ENSG00000163935.14			21261	0.005	-0.2706	No
49	CACNA1A	ENSG00000141837.20			22062	-0.016	-0.2898	No
50	PRKCA	ENSG00000154229.12			22219	-0.019	-0.2932	No
51	MRPS31	ENSG00000102738.8			22274	-0.020	-0.2941	No
52	SMAD7	ENSG00000101665.9			22592	-0.028	-0.3013	No
53	MMP16	ENSG00000156103.16			22632	-0.029	-0.3016	No
54	MT1E	ENSG00000169715.15			22802	-0.033	-0.3051	No
55	TJP1	ENSG00000104067.16			23008	-0.040	-0.3093	No
56	AGGF1	ENSG00000164252.13			23018	-0.040	-0.3087	No
57	PRDM2	ENSG00000116731.22			23037	-0.040	-0.3083	No
58	COL1A2	ENSG00000164692.17			23053	-0.041	-0.3078	No
59	VLDLR	ENSG00000147852.16			23181	-0.045	-0.3100	No
60	COL1A1	ENSG00000108821.13			23206	-0.045	-0.3097	No
61	SPOP	ENSG00000121067.19			24083	-0.066	-0.3297	No
62	SRI	ENSG00000075142.13			24123	-0.067	-0.3293	No
63	FZD2	ENSG00000180340.7			24126	-0.067	-0.3280	No
64	ADD3	ENSG00000148700.15			24136	-0.068	-0.3268	No
65	SMAD3	ENSG00000166949.16			24321	-0.074	-0.3298	No
66	PEX14	ENSG00000142655.13			24680	-0.082	-0.3369	No
67	COL3A1	ENSG00000168542.14			24737	-0.084	-0.3365	No
68	CDK13	ENSG00000065883.16			25171	-0.095	-0.3452	No
69	ACVR2A	ENSG00000121989.15			25237	-0.097	-0.3448	No
70	BHLHE40	ENSG00000134107.5			25483	-0.105	-0.3487	No
71	PMP22	ENSG00000109099.15			25773	-0.113	-0.3534	No
72	BMPR1A	ENSG00000107779.13			25782	-0.113	-0.3513	No
73	PPARG	ENSG00000132170.21			26008	-0.121	-0.3544	No
74	MAP2K5	ENSG00000137764.20			26238	-0.127	-0.3574	No
75	NIPBL	ENSG00000164190.19			26266	-0.128	-0.3554	No
76	MAPK14	ENSG00000112062.10			26416	-0.133	-0.3564	No
77	VAV2	ENSG00000160293.17			26522	-0.136	-0.3562	No
78	SCAF8	ENSG00000213079.9			26968	-0.148	-0.3640	No
79	TGFBR2	ENSG00000163513.18			26973	-0.148	-0.3611	No
80	IGFBP5	ENSG00000115461.5			27066	-0.151	-0.3603	No
81	MGMT	ENSG00000170430.10			27385	-0.160	-0.3648	No
82	ATRX	ENSG00000085224.22			27481	-0.164	-0.3638	No
83	SCHIP1	ENSG00000151967.18			27775	-0.173	-0.3675	No
84	NOTCH2	ENSG00000134250.20			28133	-0.185	-0.3724	No
85	COL11A1	ENSG00000060718.22			28377	-0.192	-0.3745	No
86	LAMC1	ENSG00000135862.6			28753	-0.203	-0.3795	No
87	ATXN1	ENSG00000124788.18			29169	-0.217	-0.3852	No
88	ARHGEF9	ENSG00000131089.16			29371	-0.224	-0.3856	No
89	PIAS3	ENSG00000131788.16			29423	-0.225	-0.3823	No
90	GRK5	ENSG00000198873.12			30006	-0.244	-0.3916	No
91	ERBB2	ENSG00000141736.13			30053	-0.246	-0.3877	No
92	CCN1	ENSG00000142871.17			30290	-0.253	-0.3883	No
93	TOGARAM1	ENSG00000198718.13			30375	-0.256	-0.3852	No
94	INPP4B	ENSG00000109452.12			30469	-0.259	-0.3822	No
95	SNAI2	ENSG00000019549.13			31053	-0.279	-0.3908	No
96	FBLN5	ENSG00000140092.14			31116	-0.281	-0.3866	No
97	SIPA1L1	ENSG00000197555.9			31158	-0.283	-0.3819	No
98	COL5A2	ENSG00000204262.14			32186	-0.304	-0.4007	No
99	AKT3	ENSG00000117020.18			35028	-0.366	-0.4626	Yes
100	MIOS	ENSG00000164654.16			35177	-0.373	-0.4587	Yes
101	DLG1	ENSG00000075711.21			35280	-0.377	-0.4535	Yes
102	PLPP3	ENSG00000162407.9			35490	-0.388	-0.4507	Yes
103	ATP2C1	ENSG00000017260.19			35680	-0.397	-0.4473	Yes
104	DLC1	ENSG00000164741.15			35687	-0.397	-0.4394	Yes
105	RASA2	ENSG00000155903.12			36064	-0.407	-0.4404	Yes
106	ANXA2	ENSG00000182718.16			36074	-0.407	-0.4323	Yes
107	FHL2	ENSG00000115641.19			36508	-0.427	-0.4342	Yes
108	DMAC2L	ENSG00000125375.15			37153	-0.461	-0.4406	Yes
109	CITED2	ENSG00000164442.10			37189	-0.463	-0.4321	Yes
110	SCN8A	ENSG00000196876.17			37337	-0.474	-0.4261	Yes
111	TGFBR3	ENSG00000069702.11			37426	-0.479	-0.4185	Yes
112	SERPINE1	ENSG00000106366.8			37533	-0.487	-0.4113	Yes
113	KIT	ENSG00000157404.15			37779	-0.511	-0.4069	Yes
114	GJA1	ENSG00000152661.9			37853	-0.517	-0.3982	Yes
115	FYN	ENSG00000010810.17			37878	-0.518	-0.3883	Yes
116	PIK3CD	ENSG00000171608.16			37991	-0.527	-0.3804	Yes
117	DAB2	ENSG00000153071.15			38148	-0.538	-0.3733	Yes
118	SDC2	ENSG00000169439.12			38187	-0.541	-0.3632	Yes
119	MGLL	ENSG00000074416.14			38196	-0.542	-0.3525	Yes
120	GCNT1	ENSG00000187210.14			38293	-0.551	-0.3437	Yes
121	ANXA4	ENSG00000196975.16			38680	-0.569	-0.3416	Yes
122	ATP2B4	ENSG00000058668.14			38776	-0.578	-0.3322	Yes
123	CDC42BPA	ENSG00000143776.18			38777	-0.578	-0.3205	Yes
124	MYC	ENSG00000136997.19			39003	-0.602	-0.3138	Yes
125	MET	ENSG00000105976.15			39317	-0.624	-0.3088	Yes
126	SLC7A1	ENSG00000139514.13			39608	-0.647	-0.3027	Yes
127	DUSP1	ENSG00000120129.6			39618	-0.648	-0.2898	Yes
128	MAP1B	ENSG00000131711.15			39648	-0.653	-0.2773	Yes
129	ADORA2B	ENSG00000170425.3			39882	-0.692	-0.2690	Yes
130	F3	ENSG00000117525.14			40005	-0.714	-0.2575	Yes
131	PDLIM5	ENSG00000163110.15			40169	-0.746	-0.2464	Yes
132	NR1D2	ENSG00000174738.13			40302	-0.778	-0.2339	Yes
133	BCKDHB	ENSG00000083123.15			40514	-0.843	-0.2219	Yes
134	NRP1	ENSG00000099250.18			40541	-0.854	-0.2053	Yes
135	NR3C1	ENSG00000113580.15			40550	-0.857	-0.1881	Yes
136	KCNMA1	ENSG00000156113.23			40594	-0.873	-0.1715	Yes
137	CAP2	ENSG00000112186.12			40604	-0.877	-0.1540	Yes
138	PLCB4	ENSG00000101333.16			40607	-0.879	-0.1362	Yes
139	APBB2	ENSG00000163697.17			40996	-1.135	-0.1227	Yes
140	CAV1	ENSG00000105974.12			41003	-1.149	-0.0996	Yes
141	DDAH1	ENSG00000153904.20			41014	-1.158	-0.0764	Yes
142	AMPH	ENSG00000078053.17			41023	-1.183	-0.0526	Yes
143	HAS2	ENSG00000170961.7			41046	-1.217	-0.0285	Yes
144	NEK7	ENSG00000151414.15			41118	-1.546	0.0010	Yes

Fig 2: HALLMARK_UV_RESPONSE_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_UV_RESPONSE_DN: Random ES distribution   
Gene set null distribution of ES for HALLMARK_UV_RESPONSE_DN