Details for gene set HALLMARK_UV_RESPONSE_UP[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	HALLMARK_UV_RESPONSE_UP
Enrichment Score (ES)	0.24348357
Normalized Enrichment Score (NES)	1.141802
Nominal p-value	0.1991404
FDR q-value	0.26719517
FWER p-Value	0.999

Fig 1: Enrichment plot: HALLMARK_UV_RESPONSE_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NR4A1	ENSG00000123358.20			437	1.041	0.0131	Yes
2	EPHX1	ENSG00000143819.12			570	0.990	0.0324	Yes
3	BMP2	ENSG00000125845.7			710	0.936	0.0503	Yes
4	OLFM1	ENSG00000130558.19			1121	0.833	0.0593	Yes
5	GAL	ENSG00000069482.7			1157	0.825	0.0772	Yes
6	CYP1A1	ENSG00000140465.14			1309	0.801	0.0918	Yes
7	CDKN1C	ENSG00000129757.13			1596	0.759	0.1021	Yes
8	E2F5	ENSG00000133740.11			2048	0.699	0.1070	Yes
9	AQP3	ENSG00000165272.16			2318	0.670	0.1157	Yes
10	CLCN2	ENSG00000114859.16			2351	0.667	0.1301	Yes
11	TCHH	ENSG00000159450.12			2593	0.644	0.1389	Yes
12	CDKN2B	ENSG00000147883.12			2601	0.644	0.1534	Yes
13	BCL2L11	ENSG00000153094.23			2637	0.640	0.1671	Yes
14	PLCL1	ENSG00000115896.16			2691	0.634	0.1803	Yes
15	CREG1	ENSG00000143162.9			2871	0.616	0.1899	Yes
16	BTG2	ENSG00000159388.6			2993	0.606	0.2008	Yes
17	DLG4	ENSG00000132535.19			3287	0.584	0.2069	Yes
18	NXF1	ENSG00000162231.14			3355	0.580	0.2185	Yes
19	SLC6A12	ENSG00000111181.12			4987	0.492	0.1899	Yes
20	DGAT1	ENSG00000185000.12			5599	0.453	0.1853	Yes
21	GCH1	ENSG00000131979.19			6236	0.421	0.1794	Yes
22	COL2A1	ENSG00000139219.19			6306	0.417	0.1872	Yes
23	RASGRP1	ENSG00000172575.12			7013	0.389	0.1789	Yes
24	FMO1	ENSG00000010932.17			7182	0.381	0.1835	Yes
25	ASNS	ENSG00000070669.17			7241	0.378	0.1907	Yes
26	BTG1	ENSG00000133639.5			7649	0.365	0.1890	Yes
27	IL6ST	ENSG00000134352.20			8019	0.360	0.1882	Yes
28	JUNB	ENSG00000171223.6			8148	0.355	0.1932	Yes
29	CDO1	ENSG00000129596.5			8894	0.340	0.1828	Yes
30	FGF18	ENSG00000156427.8			8917	0.339	0.1899	Yes
31	POLG2	ENSG00000256525.8			9023	0.334	0.1950	Yes
32	RXRB	ENSG00000204231.10			9074	0.332	0.2013	Yes
33	HMOX1	ENSG00000100292.17			9075	0.332	0.2089	Yes
34	STARD3	ENSG00000131748.16			9106	0.331	0.2157	Yes
35	TAP1	ENSG00000168394.11			9314	0.323	0.2180	Yes
36	IRF1	ENSG00000125347.14			9828	0.318	0.2127	Yes
37	RET	ENSG00000165731.20			9916	0.315	0.2178	Yes
38	TACR3	ENSG00000169836.5			9919	0.315	0.2249	Yes
39	ICAM1	ENSG00000090339.9			9924	0.314	0.2320	Yes
40	SLC6A8	ENSG00000130821.16			9951	0.313	0.2385	Yes
41	C4BPB	ENSG00000123843.13			10036	0.310	0.2435	Yes
42	MAPK8IP2	ENSG00000008735.14			10746	0.301	0.2330	No
43	LHX2	ENSG00000106689.11			11073	0.288	0.2317	No
44	CA2	ENSG00000104267.10			12533	0.253	0.2018	No
45	MMP14	ENSG00000157227.13			12590	0.252	0.2062	No
46	APOM	ENSG00000204444.11			13018	0.237	0.2012	No
47	IGFBP2	ENSG00000115457.10			13426	0.224	0.1964	No
48	POLR2H	ENSG00000163882.9			13722	0.215	0.1941	No
49	KCNH2	ENSG00000055118.15			13802	0.213	0.1970	No
50	ABCB1	ENSG00000085563.14			14109	0.202	0.1941	No
51	MGAT1	ENSG00000131446.16			14591	0.187	0.1867	No
52	MSX1	ENSG00000163132.8			14975	0.174	0.1813	No
53	HYAL2	ENSG00000068001.14			15095	0.171	0.1823	No
54	ONECUT1	ENSG00000169856.9			15209	0.168	0.1834	No
55	SQSTM1	ENSG00000161011.20			15233	0.167	0.1866	No
56	PTPRD	ENSG00000153707.17			15413	0.161	0.1859	No
57	NTRK3	ENSG00000140538.16			15638	0.155	0.1840	No
58	GRINA	ENSG00000178719.17			15785	0.151	0.1838	No
59	CDC34	ENSG00000099804.9			16311	0.137	0.1742	No
60	CHKA	ENSG00000110721.12			16361	0.135	0.1760	No
61	BSG	ENSG00000172270.19			16494	0.131	0.1758	No
62	RHOB	ENSG00000143878.10			16535	0.130	0.1778	No
63	HSPA2	ENSG00000126803.9			16949	0.118	0.1704	No
64	MAOA	ENSG00000189221.9			17441	0.106	0.1608	No
65	FOS	ENSG00000170345.10			17933	0.092	0.1510	No
66	LYN	ENSG00000254087.8			18130	0.087	0.1482	No
67	NPTXR	ENSG00000221890.4			18353	0.082	0.1446	No
68	GPX3	ENSG00000211445.12			18462	0.080	0.1438	No
69	RAB27A	ENSG00000069974.16			18661	0.075	0.1407	No
70	NKX2-5	ENSG00000183072.10			18847	0.069	0.1378	No
71	EPCAM	ENSG00000119888.10			18870	0.069	0.1388	No
72	WIZ	ENSG00000011451.19			19118	0.062	0.1342	No
73	TST	ENSG00000128311.14			19138	0.061	0.1351	No
74	AGO2	ENSG00000123908.12			19222	0.059	0.1344	No
75	SIGMAR1	ENSG00000147955.17			19374	0.054	0.1320	No
76	PARP2	ENSG00000129484.13			19624	0.048	0.1270	No
77	HTR7	ENSG00000148680.16			20138	0.036	0.1153	No
78	HLA-F	ENSG00000204642.14			20184	0.034	0.1150	No
79	CHRNA5	ENSG00000169684.13			20402	0.028	0.1103	No
80	SULT1A1	ENSG00000196502.11			20558	0.023	0.1071	No
81	UROD	ENSG00000126088.14			20903	0.015	0.0990	No
82	TUBA4A	ENSG00000127824.14			21284	0.004	0.0899	No
83	CEBPG	ENSG00000153879.9			21361	0.002	0.0881	No
84	PRPF3	ENSG00000117360.13			21532	-0.002	0.0840	No
85	MRPL23	ENSG00000214026.11			21654	-0.005	0.0811	No
86	SOD2	ENSG00000112096.18			21731	-0.007	0.0794	No
87	CNP	ENSG00000173786.17			22180	-0.018	0.0689	No
88	ATP6V1F	ENSG00000128524.5			22492	-0.026	0.0619	No
89	ACAA1	ENSG00000060971.18			22593	-0.028	0.0601	No
90	MARK2	ENSG00000072518.20			22797	-0.033	0.0559	No
91	CCK	ENSG00000187094.12			22824	-0.034	0.0561	No
92	NFKBIA	ENSG00000100906.10			22848	-0.035	0.0563	No
93	CTSV	ENSG00000136943.11			22972	-0.039	0.0542	No
94	AP2S1	ENSG00000042753.11			23077	-0.042	0.0526	No
95	ALAS1	ENSG00000023330.15			23130	-0.043	0.0523	No
96	RPN1	ENSG00000163902.12			23194	-0.045	0.0518	No
97	NPTX2	ENSG00000106236.4			23349	-0.048	0.0491	No
98	POLE3	ENSG00000148229.13			23456	-0.051	0.0477	No
99	YKT6	ENSG00000106636.8			24433	-0.075	0.0256	No
100	PRKACA	ENSG00000072062.14			24521	-0.077	0.0253	No
101	ALDOA	ENSG00000149925.20			24530	-0.078	0.0268	No
102	SPR	ENSG00000116096.6			24852	-0.087	0.0210	No
103	FOSB	ENSG00000125740.14			24969	-0.091	0.0202	No
104	TYRO3	ENSG00000092445.12			25213	-0.096	0.0165	No
105	CXCL2	ENSG00000081041.9			25575	-0.107	0.0101	No
106	KLHDC3	ENSG00000124702.18			25664	-0.110	0.0105	No
107	ARRB2	ENSG00000141480.18			25996	-0.120	0.0052	No
108	TGFBRAP1	ENSG00000135966.13			26344	-0.131	-0.0003	No
109	FURIN	ENSG00000140564.12			26542	-0.136	-0.0020	No
110	H2AFX	ENSG00000188486.3			26590	-0.138	-0.0000	No
111	NUP58	ENSG00000139496.16			26686	-0.140	0.0008	No
112	PDAP1	ENSG00000106244.13			26869	-0.145	-0.0003	No
113	ATF3	ENSG00000162772.17			27076	-0.151	-0.0019	No
114	TMBIM6	ENSG00000139644.13			27100	-0.152	0.0010	No
115	TFRC	ENSG00000072274.13			27176	-0.154	0.0027	No
116	BAK1	ENSG00000030110.13			27307	-0.158	0.0031	No
117	EIF5	ENSG00000100664.11			27344	-0.159	0.0059	No
118	HNRNPU	ENSG00000153187.20			27597	-0.167	0.0036	No
119	CYB5B	ENSG00000103018.16			27762	-0.172	0.0035	No
120	SELENOW	ENSG00000178980.15			28142	-0.185	-0.0015	No
121	PPP1R2	ENSG00000184203.8			28214	-0.187	0.0010	No
122	ATP6V1C1	ENSG00000155097.12			28302	-0.190	0.0032	No
123	PPT1	ENSG00000131238.17			28310	-0.190	0.0073	No
124	PSMC3	ENSG00000165916.8			28625	-0.200	0.0042	No
125	CYB5R1	ENSG00000159348.13			28731	-0.203	0.0063	No
126	TARS	ENSG00000113407.13			28859	-0.207	0.0079	No
127	STK25	ENSG00000115694.15			28992	-0.212	0.0095	No
128	PPIF	ENSG00000108179.14			29206	-0.218	0.0093	No
129	BID	ENSG00000015475.18			29396	-0.225	0.0098	No
130	IL6	ENSG00000136244.12			29624	-0.231	0.0095	No
131	CDC5L	ENSG00000096401.8			29701	-0.235	0.0130	No
132	RFC4	ENSG00000163918.10			30672	-0.265	-0.0046	No
133	FKBP4	ENSG00000004478.8			30809	-0.270	-0.0018	No
134	EIF2S3	ENSG00000130741.11			31765	-0.288	-0.0185	No
135	DNAJA1	ENSG00000086061.16			32115	-0.301	-0.0202	No
136	CCNE1	ENSG00000105173.14			32197	-0.305	-0.0152	No
137	CDK2	ENSG00000123374.11			32246	-0.307	-0.0094	No
138	GGH	ENSG00000137563.12			32348	-0.311	-0.0048	No
139	SLC25A4	ENSG00000151729.11			32397	-0.314	0.0012	No
140	CCND3	ENSG00000112576.12			32532	-0.317	0.0051	No
141	GRPEL1	ENSG00000109519.13			32886	-0.331	0.0041	No
142	PRKCD	ENSG00000163932.15			34711	-0.356	-0.0323	No
143	CASP3	ENSG00000164305.19			35329	-0.380	-0.0387	No
144	STIP1	ENSG00000168439.16			35973	-0.404	-0.0452	No
145	PPAT	ENSG00000128059.8			36104	-0.409	-0.0390	No
146	BTG3	ENSG00000154640.14			36289	-0.416	-0.0340	No
147	SHOX2	ENSG00000168779.19			36566	-0.430	-0.0310	No
148	ENO2	ENSG00000111674.9			36606	-0.431	-0.0221	No
149	RRAD	ENSG00000166592.12			37027	-0.454	-0.0220	No
150	PDLIM3	ENSG00000154553.15			37084	-0.457	-0.0130	No
151	HSPA13	ENSG00000155304.6			37137	-0.459	-0.0038	No
152	DNAJB1	ENSG00000132002.8			37147	-0.460	0.0065	No
153	NAT1	ENSG00000171428.14			37443	-0.481	0.0102	No
154	FEN1	ENSG00000168496.4			38636	-0.565	-0.0060	No
155	DDX21	ENSG00000165732.13			39636	-0.651	-0.0155	No
156	GLS	ENSG00000115419.12			40112	-0.734	-0.0104	No
157	AMD1	ENSG00000123505.17			40193	-0.751	0.0048	No
158	CLTB	ENSG00000175416.13			40460	-0.827	0.0171	No

Fig 2: HALLMARK_UV_RESPONSE_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_UV_RESPONSE_UP: Random ES distribution   
Gene set null distribution of ES for HALLMARK_UV_RESPONSE_UP