| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | HALLMARK_ADIPOGENESIS |
| Enrichment Score (ES) | -0.32014984 |
| Normalized Enrichment Score (NES) | -1.2853688 |
| Nominal p-value | 0.050397877 |
| FDR q-value | 0.104556605 |
| FWER p-Value | 0.911 |

| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SQOR | ENSG00000137767.14 | 64 | 3.988 | 0.0170 | No | ||
| 2 | LAMA4 | ENSG00000112769.20 | 127 | 3.582 | 0.0322 | No | ||
| 3 | CMBL | ENSG00000164237.9 | 203 | 3.287 | 0.0457 | No | ||
| 4 | STOM | ENSG00000148175.13 | 238 | 3.179 | 0.0596 | No | ||
| 5 | SLC25A1 | ENSG00000100075.10 | 364 | 2.822 | 0.0698 | No | ||
| 6 | TKT | ENSG00000163931.16 | 369 | 2.816 | 0.0827 | No | ||
| 7 | STAT5A | ENSG00000126561.16 | 383 | 2.783 | 0.0953 | No | ||
| 8 | PLIN2 | ENSG00000147872.10 | 455 | 2.674 | 0.1061 | No | ||
| 9 | GPX4 | ENSG00000167468.17 | 652 | 2.411 | 0.1127 | No | ||
| 10 | IDH1 | ENSG00000138413.13 | 771 | 2.290 | 0.1206 | No | ||
| 11 | CD302 | ENSG00000241399.7 | 1009 | 2.102 | 0.1248 | No | ||
| 12 | SOWAHC | ENSG00000198142.5 | 1034 | 2.089 | 0.1339 | No | ||
| 13 | ENPP2 | ENSG00000136960.12 | 1215 | 1.983 | 0.1389 | No | ||
| 14 | OMD | ENSG00000127083.7 | 1239 | 1.972 | 0.1475 | No | ||
| 15 | PDCD4 | ENSG00000150593.18 | 1417 | 1.879 | 0.1521 | No | ||
| 16 | RAB34 | ENSG00000109113.20 | 1570 | 1.814 | 0.1570 | No | ||
| 17 | CRAT | ENSG00000095321.17 | 1730 | 1.743 | 0.1613 | No | ||
| 18 | FAH | ENSG00000103876.12 | 1782 | 1.725 | 0.1682 | No | ||
| 19 | NABP1 | ENSG00000173559.13 | 1896 | 1.670 | 0.1733 | No | ||
| 20 | MGST3 | ENSG00000143198.13 | 1903 | 1.667 | 0.1808 | No | ||
| 21 | SLC27A1 | ENSG00000130304.17 | 2065 | 1.607 | 0.1845 | No | ||
| 22 | CD36 | ENSG00000135218.19 | 2200 | 1.566 | 0.1887 | No | ||
| 23 | NKIRAS1 | ENSG00000197885.10 | 2216 | 1.559 | 0.1956 | No | ||
| 24 | VEGFB | ENSG00000173511.9 | 2527 | 1.464 | 0.1951 | No | ||
| 25 | APLP2 | ENSG00000084234.17 | 2530 | 1.464 | 0.2019 | No | ||
| 26 | SNCG | ENSG00000173267.14 | 2602 | 1.442 | 0.2069 | No | ||
| 27 | PPARG | ENSG00000132170.21 | 2883 | 1.360 | 0.2067 | No | ||
| 28 | PTGER3 | ENSG00000050628.20 | 3014 | 1.330 | 0.2098 | No | ||
| 29 | LPL | ENSG00000175445.17 | 3048 | 1.322 | 0.2152 | No | ||
| 30 | ABCA1 | ENSG00000165029.16 | 3576 | 1.212 | 0.2085 | No | ||
| 31 | SCARB1 | ENSG00000073060.16 | 3609 | 1.204 | 0.2134 | No | ||
| 32 | DHCR7 | ENSG00000172893.15 | 3663 | 1.193 | 0.2177 | No | ||
| 33 | GPD2 | ENSG00000115159.16 | 3791 | 1.167 | 0.2201 | No | ||
| 34 | C3 | ENSG00000125730.17 | 4292 | 1.078 | 0.2135 | No | ||
| 35 | IFNGR1 | ENSG00000027697.14 | 4559 | 1.035 | 0.2121 | No | ||
| 36 | SCP2 | ENSG00000116171.18 | 4794 | 0.999 | 0.2112 | No | ||
| 37 | GBE1 | ENSG00000114480.13 | 4933 | 0.978 | 0.2126 | No | ||
| 38 | PIM3 | ENSG00000198355.5 | 5037 | 0.963 | 0.2146 | No | ||
| 39 | BAZ2A | ENSG00000076108.11 | 5431 | 0.910 | 0.2097 | No | ||
| 40 | ELMOD3 | ENSG00000115459.18 | 5474 | 0.903 | 0.2129 | No | ||
| 41 | LEP | ENSG00000174697.5 | 5681 | 0.879 | 0.2122 | No | ||
| 42 | LIFR | ENSG00000113594.10 | 5907 | 0.852 | 0.2109 | No | ||
| 43 | FABP4 | ENSG00000170323.9 | 5965 | 0.844 | 0.2135 | No | ||
| 44 | ALDH2 | ENSG00000111275.13 | 6098 | 0.829 | 0.2142 | No | ||
| 45 | EPHX2 | ENSG00000120915.14 | 6261 | 0.810 | 0.2142 | No | ||
| 46 | CAT | ENSG00000121691.7 | 6441 | 0.793 | 0.2137 | No | ||
| 47 | AGPAT3 | ENSG00000160216.19 | 6520 | 0.786 | 0.2155 | No | ||
| 48 | ANGPTL4 | ENSG00000167772.12 | 7297 | 0.710 | 0.2008 | No | ||
| 49 | FZD4 | ENSG00000174804.4 | 7368 | 0.704 | 0.2024 | No | ||
| 50 | PHYH | ENSG00000107537.14 | 7726 | 0.670 | 0.1972 | No | ||
| 51 | ITIH5 | ENSG00000123243.15 | 7798 | 0.664 | 0.1986 | No | ||
| 52 | UCK1 | ENSG00000130717.13 | 7844 | 0.660 | 0.2006 | No | ||
| 53 | GPX3 | ENSG00000211445.12 | 7962 | 0.650 | 0.2009 | No | ||
| 54 | CMPK1 | ENSG00000162368.13 | 7991 | 0.648 | 0.2033 | No | ||
| 55 | ACADS | ENSG00000122971.9 | 7993 | 0.648 | 0.2062 | No | ||
| 56 | LTC4S | ENSG00000213316.10 | 8139 | 0.635 | 0.2058 | No | ||
| 57 | GPAT4 | ENSG00000158669.11 | 8394 | 0.613 | 0.2027 | No | ||
| 58 | REEP6 | ENSG00000115255.11 | 8727 | 0.589 | 0.1977 | No | ||
| 59 | DRAM2 | ENSG00000156171.14 | 9328 | 0.548 | 0.1863 | No | ||
| 60 | TST | ENSG00000128311.14 | 9625 | 0.528 | 0.1818 | No | ||
| 61 | ANGPT1 | ENSG00000154188.10 | 9780 | 0.522 | 0.1807 | No | ||
| 62 | MGLL | ENSG00000074416.14 | 10076 | 0.505 | 0.1761 | No | ||
| 63 | CDKN2C | ENSG00000123080.12 | 10414 | 0.484 | 0.1705 | No | ||
| 64 | PFKFB3 | ENSG00000170525.21 | 10834 | 0.456 | 0.1629 | No | ||
| 65 | RETSAT | ENSG00000042445.14 | 11072 | 0.439 | 0.1594 | No | ||
| 66 | ADIPOR2 | ENSG00000006831.10 | 11292 | 0.427 | 0.1563 | No | ||
| 67 | TANK | ENSG00000136560.14 | 11874 | 0.395 | 0.1446 | No | ||
| 68 | ADIG | ENSG00000182035.12 | 12490 | 0.365 | 0.1319 | No | ||
| 69 | ADIPOQ | ENSG00000181092.10 | 12514 | 0.365 | 0.1331 | No | ||
| 70 | SPARCL1 | ENSG00000152583.12 | 15335 | 0.283 | 0.0687 | No | ||
| 71 | PEMT | ENSG00000133027.18 | 15342 | 0.283 | 0.0699 | No | ||
| 72 | NMT1 | ENSG00000136448.12 | 16003 | 0.249 | 0.0556 | No | ||
| 73 | CCNG2 | ENSG00000138764.15 | 16472 | 0.221 | 0.0458 | No | ||
| 74 | IDH3G | ENSG00000067829.19 | 17636 | 0.167 | 0.0194 | No | ||
| 75 | CAVIN1 | ENSG00000177469.13 | 17895 | 0.152 | 0.0141 | No | ||
| 76 | COL15A1 | ENSG00000204291.11 | 18002 | 0.146 | 0.0123 | No | ||
| 77 | QDPR | ENSG00000151552.12 | 18140 | 0.139 | 0.0098 | No | ||
| 78 | UBQLN1 | ENSG00000135018.14 | 18240 | 0.134 | 0.0081 | No | ||
| 79 | CIDEA | ENSG00000176194.18 | 18690 | 0.113 | -0.0018 | No | ||
| 80 | ACOX1 | ENSG00000161533.12 | 18902 | 0.103 | -0.0063 | No | ||
| 81 | MIGA2 | ENSG00000148343.18 | 18951 | 0.101 | -0.0069 | No | ||
| 82 | MYLK | ENSG00000065534.18 | 19434 | 0.074 | -0.0178 | No | ||
| 83 | MRAP | ENSG00000170262.12 | 19833 | 0.054 | -0.0268 | No | ||
| 84 | ARAF | ENSG00000078061.13 | 20011 | 0.048 | -0.0307 | No | ||
| 85 | SOD1 | ENSG00000142168.14 | 20939 | -0.001 | -0.0523 | No | ||
| 86 | JAGN1 | ENSG00000171135.15 | 21072 | -0.008 | -0.0553 | No | ||
| 87 | UQCR11 | ENSG00000127540.12 | 21789 | -0.046 | -0.0718 | No | ||
| 88 | PEX14 | ENSG00000142655.13 | 21793 | -0.047 | -0.0717 | No | ||
| 89 | UBC | ENSG00000150991.15 | 21944 | -0.054 | -0.0749 | No | ||
| 90 | RMDN3 | ENSG00000137824.16 | 22849 | -0.105 | -0.0955 | No | ||
| 91 | SLC1A5 | ENSG00000105281.12 | 23007 | -0.112 | -0.0986 | No | ||
| 92 | GPHN | ENSG00000171723.15 | 23382 | -0.134 | -0.1067 | No | ||
| 93 | MAP4K3 | ENSG00000011566.15 | 23401 | -0.135 | -0.1065 | No | ||
| 94 | CHUK | ENSG00000213341.11 | 24032 | -0.173 | -0.1204 | No | ||
| 95 | ETFB | ENSG00000105379.9 | 24745 | -0.215 | -0.1360 | No | ||
| 96 | DHRS7 | ENSG00000100612.14 | 25569 | -0.232 | -0.1541 | No | ||
| 97 | SAMM50 | ENSG00000100347.15 | 25977 | -0.259 | -0.1624 | No | ||
| 98 | CHCHD10 | ENSG00000250479.8 | 27023 | -0.275 | -0.1854 | No | ||
| 99 | NDUFA5 | ENSG00000128609.15 | 27038 | -0.276 | -0.1845 | No | ||
| 100 | ORM1 | ENSG00000229314.5 | 27613 | -0.302 | -0.1964 | No | ||
| 101 | LIPE | ENSG00000079435.10 | 28239 | -0.325 | -0.2095 | No | ||
| 102 | PRDX3 | ENSG00000165672.7 | 28518 | -0.337 | -0.2144 | No | ||
| 103 | SUCLG1 | ENSG00000163541.12 | 28761 | -0.349 | -0.2184 | No | ||
| 104 | TALDO1 | ENSG00000177156.11 | 29360 | -0.367 | -0.2307 | No | ||
| 105 | DHRS7B | ENSG00000109016.17 | 29632 | -0.383 | -0.2352 | No | ||
| 106 | COX6A1 | ENSG00000111775.3 | 29637 | -0.384 | -0.2335 | No | ||
| 107 | ACLY | ENSG00000131473.17 | 30065 | -0.411 | -0.2416 | No | ||
| 108 | NDUFS3 | ENSG00000213619.10 | 30108 | -0.414 | -0.2406 | No | ||
| 109 | SDHC | ENSG00000143252.14 | 30372 | -0.429 | -0.2447 | No | ||
| 110 | BCL2L13 | ENSG00000099968.18 | 30555 | -0.438 | -0.2470 | No | ||
| 111 | NDUFB7 | ENSG00000099795.7 | 30995 | -0.459 | -0.2551 | No | ||
| 112 | ATP5PO | ENSG00000241837.7 | 31091 | -0.467 | -0.2551 | No | ||
| 113 | REEP5 | ENSG00000129625.13 | 31342 | -0.482 | -0.2587 | No | ||
| 114 | PGM1 | ENSG00000079739.17 | 31611 | -0.495 | -0.2626 | No | ||
| 115 | MARC2 | ENSG00000117791.16 | 31737 | -0.499 | -0.2632 | No | ||
| 116 | PPP1R15B | ENSG00000158615.9 | 32049 | -0.517 | -0.2681 | No | ||
| 117 | DNAJC15 | ENSG00000120675.6 | 32082 | -0.520 | -0.2664 | No | ||
| 118 | ESRRA | ENSG00000173153.14 | 32291 | -0.533 | -0.2688 | No | ||
| 119 | MTCH2 | ENSG00000109919.10 | 32681 | -0.558 | -0.2753 | No | ||
| 120 | MCCC1 | ENSG00000078070.13 | 32803 | -0.569 | -0.2755 | No | ||
| 121 | POR | ENSG00000127948.16 | 32862 | -0.573 | -0.2742 | No | ||
| 122 | SDHB | ENSG00000117118.9 | 33081 | -0.589 | -0.2765 | No | ||
| 123 | ECH1 | ENSG00000104823.9 | 33133 | -0.593 | -0.2749 | No | ||
| 124 | RTN3 | ENSG00000133318.14 | 33399 | -0.613 | -0.2783 | No | ||
| 125 | ITSN1 | ENSG00000205726.15 | 33605 | -0.630 | -0.2801 | No | ||
| 126 | DNAJB9 | ENSG00000128590.5 | 33867 | -0.651 | -0.2832 | No | ||
| 127 | ADCY6 | ENSG00000174233.11 | 34252 | -0.679 | -0.2890 | No | ||
| 128 | COX8A | ENSG00000176340.4 | 34436 | -0.697 | -0.2900 | No | ||
| 129 | COQ5 | ENSG00000110871.15 | 34592 | -0.709 | -0.2903 | No | ||
| 130 | G3BP2 | ENSG00000138757.14 | 35427 | -0.780 | -0.3062 | No | ||
| 131 | PREB | ENSG00000138073.14 | 35458 | -0.783 | -0.3032 | No | ||
| 132 | HIBCH | ENSG00000198130.16 | 35612 | -0.799 | -0.3031 | No | ||
| 133 | DGAT1 | ENSG00000185000.12 | 35854 | -0.825 | -0.3049 | No | ||
| 134 | GHITM | ENSG00000165678.21 | 36073 | -0.852 | -0.3060 | No | ||
| 135 | SLC5A6 | ENSG00000138074.15 | 36328 | -0.881 | -0.3078 | No | ||
| 136 | PFKL | ENSG00000141959.17 | 36723 | -0.933 | -0.3127 | No | ||
| 137 | ATP1B3 | ENSG00000069849.11 | 37044 | -0.973 | -0.3156 | Yes | ||
| 138 | APOE | ENSG00000130203.10 | 37045 | -0.973 | -0.3111 | Yes | ||
| 139 | TOB1 | ENSG00000141232.5 | 37303 | -1.007 | -0.3124 | Yes | ||
| 140 | DLAT | ENSG00000150768.15 | 37363 | -1.015 | -0.3091 | Yes | ||
| 141 | CPT2 | ENSG00000157184.7 | 37417 | -1.022 | -0.3056 | Yes | ||
| 142 | COQ9 | ENSG00000088682.14 | 37436 | -1.024 | -0.3013 | Yes | ||
| 143 | RREB1 | ENSG00000124782.20 | 37653 | -1.060 | -0.3014 | Yes | ||
| 144 | RNF11 | ENSG00000123091.5 | 37745 | -1.076 | -0.2985 | Yes | ||
| 145 | MRPL15 | ENSG00000137547.9 | 37824 | -1.087 | -0.2953 | Yes | ||
| 146 | UQCR10 | ENSG00000184076.13 | 37826 | -1.087 | -0.2903 | Yes | ||
| 147 | COX7B | ENSG00000131174.7 | 37903 | -1.101 | -0.2870 | Yes | ||
| 148 | BCL6 | ENSG00000113916.18 | 38004 | -1.118 | -0.2841 | Yes | ||
| 149 | CD151 | ENSG00000177697.19 | 38093 | -1.134 | -0.2809 | Yes | ||
| 150 | UQCRQ | ENSG00000164405.11 | 38111 | -1.136 | -0.2760 | Yes | ||
| 151 | PTCD3 | ENSG00000132300.19 | 38208 | -1.154 | -0.2729 | Yes | ||
| 152 | AIFM1 | ENSG00000156709.14 | 38213 | -1.156 | -0.2676 | Yes | ||
| 153 | ELOVL6 | ENSG00000170522.9 | 38394 | -1.186 | -0.2663 | Yes | ||
| 154 | LPCAT3 | ENSG00000111684.11 | 38555 | -1.216 | -0.2644 | Yes | ||
| 155 | SLC25A10 | ENSG00000183048.12 | 38567 | -1.217 | -0.2590 | Yes | ||
| 156 | ATL2 | ENSG00000119787.14 | 38596 | -1.222 | -0.2540 | Yes | ||
| 157 | ALDOA | ENSG00000149925.20 | 38602 | -1.223 | -0.2485 | Yes | ||
| 158 | CYC1 | ENSG00000179091.5 | 38710 | -1.245 | -0.2452 | Yes | ||
| 159 | BCKDHA | ENSG00000248098.12 | 38800 | -1.267 | -0.2414 | Yes | ||
| 160 | UQCRC1 | ENSG00000010256.11 | 38824 | -1.273 | -0.2360 | Yes | ||
| 161 | ACO2 | ENSG00000100412.16 | 38900 | -1.290 | -0.2318 | Yes | ||
| 162 | DBT | ENSG00000137992.14 | 38918 | -1.293 | -0.2262 | Yes | ||
| 163 | PHLDB1 | ENSG00000019144.19 | 38946 | -1.297 | -0.2208 | Yes | ||
| 164 | CS | ENSG00000062485.19 | 39089 | -1.328 | -0.2180 | Yes | ||
| 165 | MDH2 | ENSG00000146701.12 | 39149 | -1.341 | -0.2131 | Yes | ||
| 166 | ACADM | ENSG00000117054.13 | 39201 | -1.353 | -0.2080 | Yes | ||
| 167 | DECR1 | ENSG00000104325.7 | 39242 | -1.363 | -0.2026 | Yes | ||
| 168 | COL4A1 | ENSG00000187498.16 | 39310 | -1.380 | -0.1978 | Yes | ||
| 169 | COQ3 | ENSG00000132423.12 | 39314 | -1.381 | -0.1915 | Yes | ||
| 170 | ME1 | ENSG00000065833.9 | 39319 | -1.382 | -0.1852 | Yes | ||
| 171 | ECHS1 | ENSG00000127884.5 | 39473 | -1.417 | -0.1822 | Yes | ||
| 172 | DLD | ENSG00000091140.14 | 39495 | -1.421 | -0.1761 | Yes | ||
| 173 | ABCB8 | ENSG00000197150.12 | 39677 | -1.460 | -0.1735 | Yes | ||
| 174 | ACADL | ENSG00000115361.8 | 39688 | -1.463 | -0.1670 | Yes | ||
| 175 | CAVIN2 | ENSG00000168497.5 | 39781 | -1.487 | -0.1622 | Yes | ||
| 176 | SLC19A1 | ENSG00000173638.19 | 39857 | -1.508 | -0.1570 | Yes | ||
| 177 | IMMT | ENSG00000132305.20 | 39920 | -1.527 | -0.1513 | Yes | ||
| 178 | AK2 | ENSG00000004455.17 | 39939 | -1.532 | -0.1446 | Yes | ||
| 179 | IDH3A | ENSG00000166411.14 | 39940 | -1.532 | -0.1375 | Yes | ||
| 180 | HADH | ENSG00000138796.16 | 40435 | -1.667 | -0.1413 | Yes | ||
| 181 | GRPEL1 | ENSG00000109519.13 | 40485 | -1.684 | -0.1347 | Yes | ||
| 182 | GPAM | ENSG00000119927.14 | 40785 | -1.781 | -0.1334 | Yes | ||
| 183 | SULT1A1 | ENSG00000196502.11 | 40850 | -1.802 | -0.1265 | Yes | ||
| 184 | ACAA2 | ENSG00000167315.18 | 41011 | -1.873 | -0.1215 | Yes | ||
| 185 | GADD45A | ENSG00000116717.13 | 41218 | -1.966 | -0.1172 | Yes | ||
| 186 | PPM1B | ENSG00000138032.21 | 41267 | -1.984 | -0.1091 | Yes | ||
| 187 | ESYT1 | ENSG00000139641.12 | 41393 | -2.061 | -0.1025 | Yes | ||
| 188 | NDUFAB1 | ENSG00000004779.10 | 41690 | -2.242 | -0.0990 | Yes | ||
| 189 | ARL4A | ENSG00000122644.13 | 41707 | -2.259 | -0.0889 | Yes | ||
| 190 | YWHAG | ENSG00000170027.7 | 42117 | -2.593 | -0.0864 | Yes | ||
| 191 | RIOK3 | ENSG00000101782.15 | 42254 | -2.773 | -0.0767 | Yes | ||
| 192 | SSPN | ENSG00000123096.11 | 42412 | -2.994 | -0.0665 | Yes | ||
| 193 | HSPB8 | ENSG00000152137.6 | 42810 | -3.949 | -0.0574 | Yes | ||
| 194 | ITGA7 | ENSG00000135424.16 | 42920 | -4.354 | -0.0398 | Yes | ||
| 195 | UCP2 | ENSG00000175567.10 | 42987 | -4.667 | -0.0197 | Yes | ||
| 196 | SORBS1 | ENSG00000095637.22 | 43061 | -4.908 | 0.0014 | Yes |

