Details for gene set HALLMARK_ALLOGRAFT_REJECTION[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2M
GeneSet	HALLMARK_ALLOGRAFT_REJECTION
Enrichment Score (ES)	-0.280949
Normalized Enrichment Score (NES)	-1.1315613
Nominal p-value	0.20905459
FDR q-value	0.25065535
FWER p-Value	1.0

Fig 1: Enrichment plot: HALLMARK_ALLOGRAFT_REJECTION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IL7	ENSG00000104432.14			187	3.332	0.0123	No
2	IL16	ENSG00000172349.17			194	3.310	0.0287	No
3	SOCS5	ENSG00000171150.9			277	3.052	0.0421	No
4	HLA-E	ENSG00000204592.9			401	2.753	0.0530	No
5	CTSS	ENSG00000163131.11			442	2.687	0.0655	No
6	EGFR	ENSG00000146648.18			529	2.570	0.0764	No
7	TIMP1	ENSG00000102265.12			582	2.491	0.0876	No
8	ELANE	ENSG00000197561.7			623	2.444	0.0989	No
9	FYB1	ENSG00000082074.18			857	2.213	0.1046	No
10	IFNGR2	ENSG00000159128.14			882	2.184	0.1149	No
11	HLA-DMA	ENSG00000204257.15			906	2.165	0.1252	No
12	FAS	ENSG00000026103.22			911	2.164	0.1360	No
13	B2M	ENSG00000166710.20			923	2.152	0.1465	No
14	IGSF6	ENSG00000140749.9			961	2.126	0.1563	No
15	CAPG	ENSG00000042493.16			994	2.108	0.1661	No
16	SPI1	ENSG00000066336.11			1079	2.062	0.1744	No
17	STAT1	ENSG00000115415.18			1379	1.893	0.1769	No
18	CD47	ENSG00000196776.16			1555	1.816	0.1819	No
19	ELF4	ENSG00000102034.16			1720	1.748	0.1869	No
20	APBB1	ENSG00000166313.19			1899	1.669	0.1911	No
21	BCL10	ENSG00000142867.14			1956	1.649	0.1980	No
22	TLR3	ENSG00000164342.12			2177	1.573	0.2008	No
23	CSF1	ENSG00000184371.14			2219	1.559	0.2076	No
24	THY1	ENSG00000154096.13			2244	1.552	0.2148	No
25	NCK1	ENSG00000158092.7			2423	1.498	0.2182	No
26	IL13	ENSG00000169194.9			2466	1.483	0.2246	No
27	DEGS1	ENSG00000143753.13			3004	1.332	0.2188	No
28	PSMB10	ENSG00000205220.12			3086	1.313	0.2234	No
29	CCL7	ENSG00000108688.11			3096	1.310	0.2298	No
30	HLA-G	ENSG00000204632.11			3266	1.274	0.2322	No
31	DYRK3	ENSG00000143479.17			3399	1.246	0.2354	No
32	INHBB	ENSG00000163083.6			3525	1.221	0.2386	No
33	FGR	ENSG00000000938.13			3622	1.201	0.2424	No
34	ICAM1	ENSG00000090339.9			4204	1.093	0.2343	No
35	RPS19	ENSG00000105372.8			4406	1.060	0.2349	No
36	IFNGR1	ENSG00000027697.14			4559	1.035	0.2366	No
37	RPS9	ENSG00000170889.14			4738	1.009	0.2375	No
38	CD74	ENSG00000019582.15			4804	0.997	0.2409	No
39	EREG	ENSG00000124882.4			4928	0.979	0.2430	No
40	CD79A	ENSG00000105369.9			5776	0.867	0.2276	No
41	SOCS1	ENSG00000185338.5			5891	0.854	0.2292	No
42	STAT4	ENSG00000138378.19			5947	0.847	0.2321	No
43	IL15	ENSG00000164136.17			6136	0.824	0.2319	No
44	TAPBP	ENSG00000231925.11			6179	0.819	0.2350	No
45	NLRP3	ENSG00000162711.17			6212	0.815	0.2383	No
46	LY75	ENSG00000054219.11			6402	0.797	0.2379	No
47	IL2RB	ENSG00000100385.14			6472	0.790	0.2403	No
48	CCR1	ENSG00000163823.4			6476	0.790	0.2442	No
49	IL27RA	ENSG00000104998.4			6763	0.761	0.2413	No
50	IL18	ENSG00000150782.12			6797	0.757	0.2443	No
51	IL18RAP	ENSG00000115607.9			7077	0.730	0.2415	No
52	CCL2	ENSG00000108691.9			7391	0.701	0.2377	No
53	F2R	ENSG00000181104.7			7392	0.701	0.2412	No
54	IL4	ENSG00000113520.11			7818	0.662	0.2346	No
55	CD3G	ENSG00000160654.10			7987	0.648	0.2340	No
56	CD40	ENSG00000101017.14			8044	0.644	0.2359	No
57	CCL13	ENSG00000181374.8			8740	0.588	0.2226	No
58	CCL19	ENSG00000172724.12			8785	0.584	0.2245	No
59	CCL5	ENSG00000271503.6			8798	0.583	0.2272	No
60	CCL11	ENSG00000172156.4			8815	0.582	0.2297	No
61	CCL4	ENSG00000275302.2			9015	0.568	0.2279	No
62	IRF4	ENSG00000137265.15			9062	0.567	0.2297	No
63	TLR2	ENSG00000137462.8			9313	0.549	0.2266	No
64	CXCL9	ENSG00000138755.6			9551	0.534	0.2237	No
65	IL2RA	ENSG00000134460.17			9914	0.516	0.2179	No
66	GCNT1	ENSG00000187210.14			10361	0.487	0.2099	No
67	HLA-A	ENSG00000206503.13			10612	0.470	0.2065	No
68	C2	ENSG00000166278.15			10689	0.466	0.2070	No
69	LYN	ENSG00000254087.8			10784	0.460	0.2071	No
70	LCP2	ENSG00000043462.12			11106	0.438	0.2019	No
71	GPR65	ENSG00000140030.6			11401	0.420	0.1971	No
72	CRTAM	ENSG00000109943.9			11781	0.398	0.1903	No
73	KLRD1	ENSG00000134539.17			12536	0.363	0.1745	No
74	HCLS1	ENSG00000180353.11			13234	0.344	0.1600	No
75	MBL2	ENSG00000165471.6			13582	0.322	0.1535	No
76	TAP1	ENSG00000168394.11			14010	0.316	0.1452	No
77	HLA-DRA	ENSG00000204287.14			14089	0.312	0.1449	No
78	IRF7	ENSG00000185507.21			14110	0.311	0.1460	No
79	LCK	ENSG00000182866.17			15496	0.275	0.1151	No
80	TAP2	ENSG00000204267.15			16226	0.235	0.0993	No
81	WAS	ENSG00000015285.10			16612	0.214	0.0914	No
82	IL12RB1	ENSG00000096996.16			16657	0.212	0.0915	No
83	CD8B	ENSG00000172116.23			16808	0.206	0.0890	No
84	HLA-DMB	ENSG00000242574.9			17415	0.177	0.0758	No
85	IL1B	ENSG00000125538.12			17487	0.172	0.0750	No
86	NOS2	ENSG00000007171.18			17510	0.171	0.0753	No
87	CD40LG	ENSG00000102245.7			17639	0.167	0.0732	No
88	IL12A	ENSG00000168811.7			17967	0.148	0.0663	No
89	HDAC9	ENSG00000048052.21			18434	0.129	0.0561	No
90	RPL9	ENSG00000163682.16			18659	0.115	0.0514	No
91	CSK	ENSG00000103653.16			19360	0.080	0.0355	No
92	CD7	ENSG00000173762.8			20028	0.047	0.0202	No
93	CDKN2A	ENSG00000147889.17			20700	0.012	0.0046	No
94	IFNAR2	ENSG00000159110.19			20837	0.005	0.0015	No
95	CFP	ENSG00000126759.13			21023	-0.005	-0.0028	No
96	TRAF2	ENSG00000127191.18			21170	-0.015	-0.0061	No
97	SIT1	ENSG00000137078.9			21183	-0.015	-0.0063	No
98	CD8A	ENSG00000153563.15			21477	-0.031	-0.0130	No
99	CD4	ENSG00000010610.10			22265	-0.072	-0.0310	No
100	IL12B	ENSG00000113302.4			22283	-0.073	-0.0310	No
101	AARS	ENSG00000090861.15			22345	-0.077	-0.0320	No
102	UBE2D1	ENSG00000072401.15			22471	-0.083	-0.0345	No
103	ACVR2A	ENSG00000121989.15			22689	-0.096	-0.0391	No
104	PRKCG	ENSG00000126583.11			22711	-0.097	-0.0391	No
105	RPL39	ENSG00000198918.8			22868	-0.106	-0.0422	No
106	NPM1	ENSG00000181163.13			22984	-0.111	-0.0443	No
107	CD96	ENSG00000153283.13			23084	-0.118	-0.0460	No
108	TLR6	ENSG00000174130.12			23104	-0.119	-0.0459	No
109	FCGR2B	ENSG00000072694.20			23742	-0.153	-0.0600	No
110	RIPK2	ENSG00000104312.8			24469	-0.197	-0.0759	No
111	GZMA	ENSG00000145649.8			25202	-0.223	-0.0918	No
112	TRAT1	ENSG00000163519.14			25439	-0.223	-0.0962	No
113	CD2	ENSG00000116824.5			25496	-0.227	-0.0964	No
114	PRKCB	ENSG00000166501.14			25604	-0.234	-0.0977	No
115	HLA-DOB	ENSG00000241106.8			25886	-0.253	-0.1030	No
116	RPS3A	ENSG00000145425.10			26036	-0.262	-0.1051	No
117	CCND3	ENSG00000112576.12			26472	-0.264	-0.1140	No
118	CD247	ENSG00000198821.10			28109	-0.318	-0.1505	No
119	FASLG	ENSG00000117560.8			28350	-0.331	-0.1544	No
120	IRF8	ENSG00000140968.11			28903	-0.351	-0.1655	No
121	ITGAL	ENSG00000005844.18			29099	-0.354	-0.1683	No
122	CD3E	ENSG00000198851.9			29128	-0.355	-0.1672	No
123	CD86	ENSG00000114013.16			29238	-0.360	-0.1679	No
124	STAB1	ENSG00000010327.10			29747	-0.390	-0.1778	No
125	HLA-DQA1	ENSG00000196735.12			29924	-0.400	-0.1799	No
126	LTB	ENSG00000227507.2			30077	-0.411	-0.1814	No
127	CCL22	ENSG00000102962.5			30346	-0.429	-0.1855	No
128	HLA-DOA	ENSG00000204252.14			31036	-0.462	-0.1992	No
129	MMP9	ENSG00000100985.7			31139	-0.471	-0.1992	No
130	EIF3D	ENSG00000100353.18			31314	-0.479	-0.2009	No
131	PRF1	ENSG00000180644.8			31454	-0.487	-0.2017	No
132	JAK2	ENSG00000096968.13			31758	-0.501	-0.2062	No
133	CD3D	ENSG00000167286.9			32821	-0.570	-0.2281	No
134	ETS1	ENSG00000134954.14			33090	-0.589	-0.2314	No
135	BCL3	ENSG00000069399.15			33424	-0.615	-0.2361	No
136	IKBKB	ENSG00000104365.15			33503	-0.622	-0.2348	No
137	AKT1	ENSG00000142208.16			33520	-0.623	-0.2320	No
138	MRPL3	ENSG00000114686.9			33685	-0.637	-0.2327	No
139	CXCL13	ENSG00000156234.7			34771	-0.721	-0.2543	No
140	PF4	ENSG00000163737.4			34978	-0.739	-0.2554	No
141	GZMB	ENSG00000100453.13			35349	-0.772	-0.2602	No
142	IL4R	ENSG00000077238.14			35619	-0.801	-0.2624	No
143	RARS	ENSG00000113643.9			35724	-0.811	-0.2608	No
144	EIF4G3	ENSG00000075151.20			35747	-0.813	-0.2573	No
145	MTIF2	ENSG00000085760.15			35779	-0.816	-0.2539	No
146	FLNA	ENSG00000196924.17			36458	-0.895	-0.2652	No
147	GLMN	ENSG00000174842.17			36722	-0.932	-0.2667	No
148	WARS	ENSG00000140105.18			37336	-1.011	-0.2759	Yes
149	IL6	ENSG00000136244.12			37366	-1.015	-0.2715	Yes
150	TNF	ENSG00000232810.4			37586	-1.048	-0.2713	Yes
151	TLR1	ENSG00000174125.8			37664	-1.061	-0.2678	Yes
152	ABI1	ENSG00000136754.17			37724	-1.071	-0.2638	Yes
153	CCR2	ENSG00000121807.5			37775	-1.080	-0.2596	Yes
154	HIF1A	ENSG00000100644.17			37783	-1.081	-0.2544	Yes
155	ICOSLG	ENSG00000160223.17			38080	-1.131	-0.2556	Yes
156	PTPN6	ENSG00000111679.17			38407	-1.189	-0.2572	Yes
157	TGFB1	ENSG00000105329.10			38478	-1.201	-0.2529	Yes
158	BRCA1	ENSG00000012048.22			38494	-1.205	-0.2472	Yes
159	UBE2N	ENSG00000177889.10			38590	-1.222	-0.2433	Yes
160	DARS	ENSG00000115866.11			38890	-1.287	-0.2438	Yes
161	GBP2	ENSG00000162645.13			39071	-1.325	-0.2414	Yes
162	EIF3A	ENSG00000107581.13			39106	-1.332	-0.2355	Yes
163	MAP4K1	ENSG00000104814.13			39205	-1.355	-0.2310	Yes
164	CD80	ENSG00000121594.12			39254	-1.364	-0.2253	Yes
165	ITK	ENSG00000113263.12			39299	-1.376	-0.2194	Yes
166	ZAP70	ENSG00000115085.13			39536	-1.429	-0.2178	Yes
167	EIF5A	ENSG00000132507.18			39745	-1.477	-0.2152	Yes
168	ACHE	ENSG00000087085.15			39892	-1.520	-0.2110	Yes
169	ABCE1	ENSG00000164163.11			40196	-1.598	-0.2101	Yes
170	TPD52	ENSG00000076554.15			40238	-1.609	-0.2030	Yes
171	GALNT1	ENSG00000141429.13			40285	-1.621	-0.1959	Yes
172	MAP3K7	ENSG00000135341.18			40323	-1.633	-0.1886	Yes
173	CD1D	ENSG00000158473.6			40635	-1.730	-0.1872	Yes
174	CXCR3	ENSG00000186810.8			40916	-1.830	-0.1846	Yes
175	NME1	ENSG00000239672.7			41010	-1.873	-0.1774	Yes
176	CCR5	ENSG00000160791.13			41133	-1.925	-0.1706	Yes
177	ITGB2	ENSG00000160255.18			41252	-1.979	-0.1634	Yes
178	INHBA	ENSG00000122641.11			41421	-2.082	-0.1569	Yes
179	IL11	ENSG00000095752.7			41469	-2.115	-0.1475	Yes
180	ST8SIA4	ENSG00000113532.13			41479	-2.122	-0.1370	Yes
181	TGFB2	ENSG00000092969.12			41517	-2.139	-0.1272	Yes
182	EIF3J	ENSG00000104131.13			41556	-2.168	-0.1172	Yes
183	SRGN	ENSG00000122862.5			41600	-2.195	-0.1073	Yes
184	F2	ENSG00000180210.14			41777	-2.308	-0.0998	Yes
185	IL2RG	ENSG00000147168.12			41862	-2.374	-0.0899	Yes
186	CCND2	ENSG00000118971.8			41960	-2.462	-0.0798	Yes
187	PTPRC	ENSG00000081237.20			42203	-2.706	-0.0719	Yes
188	BCAT1	ENSG00000060982.15			42267	-2.792	-0.0594	Yes
189	RPL3L	ENSG00000140986.8			42565	-3.235	-0.0502	Yes
190	IL10	ENSG00000136634.7			42757	-3.743	-0.0359	Yes
191	LIF	ENSG00000128342.5			42847	-4.098	-0.0174	Yes
192	CD28	ENSG00000178562.18			43006	-4.748	0.0026	Yes

Fig 2: HALLMARK_ALLOGRAFT_REJECTION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_ALLOGRAFT_REJECTION: Random ES distribution   
Gene set null distribution of ES for HALLMARK_ALLOGRAFT_REJECTION