Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | HALLMARK_CHOLESTEROL_HOMEOSTASIS |
| Enrichment Score (ES) | 0.61756176 |
| Normalized Enrichment Score (NES) | 2.368343 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GSTM2 | ENSG00000213366.13 | 105 | 3.658 | 0.0351 | Yes | ||
| 2 | LGALS3 | ENSG00000131981.16 | 150 | 3.486 | 0.0699 | Yes | ||
| 3 | FADS2 | ENSG00000134824.14 | 326 | 2.899 | 0.0956 | Yes | ||
| 4 | LSS | ENSG00000160285.15 | 553 | 2.538 | 0.1164 | Yes | ||
| 5 | SQLE | ENSG00000104549.12 | 823 | 2.241 | 0.1331 | Yes | ||
| 6 | CYP51A1 | ENSG00000001630.17 | 829 | 2.232 | 0.1559 | Yes | ||
| 7 | ACAT2 | ENSG00000120437.9 | 847 | 2.219 | 0.1783 | Yes | ||
| 8 | LDLR | ENSG00000130164.13 | 900 | 2.174 | 0.1994 | Yes | ||
| 9 | PLSCR1 | ENSG00000188313.13 | 1031 | 2.090 | 0.2178 | Yes | ||
| 10 | SCD | ENSG00000099194.6 | 1288 | 1.946 | 0.2319 | Yes | ||
| 11 | ADH4 | ENSG00000198099.8 | 1310 | 1.932 | 0.2512 | Yes | ||
| 12 | HMGCR | ENSG00000113161.16 | 1456 | 1.862 | 0.2670 | Yes | ||
| 13 | ACSS2 | ENSG00000131069.20 | 1499 | 1.845 | 0.2849 | Yes | ||
| 14 | CD9 | ENSG00000010278.14 | 1562 | 1.814 | 0.3021 | Yes | ||
| 15 | ETHE1 | ENSG00000105755.8 | 1563 | 1.814 | 0.3207 | Yes | ||
| 16 | CXCL16 | ENSG00000161921.15 | 1571 | 1.814 | 0.3392 | Yes | ||
| 17 | PNRC1 | ENSG00000146278.11 | 1595 | 1.801 | 0.3572 | Yes | ||
| 18 | MVK | ENSG00000110921.14 | 1775 | 1.727 | 0.3707 | Yes | ||
| 19 | HSD17B7 | ENSG00000132196.14 | 1994 | 1.633 | 0.3824 | Yes | ||
| 20 | ALDOC | ENSG00000109107.14 | 2040 | 1.615 | 0.3980 | Yes | ||
| 21 | ABCA2 | ENSG00000107331.17 | 2112 | 1.595 | 0.4127 | Yes | ||
| 22 | PCYT2 | ENSG00000185813.10 | 2169 | 1.576 | 0.4276 | Yes | ||
| 23 | TP53INP1 | ENSG00000164938.14 | 2194 | 1.568 | 0.4431 | Yes | ||
| 24 | CLU | ENSG00000120885.22 | 2415 | 1.500 | 0.4534 | Yes | ||
| 25 | FBXO6 | ENSG00000116663.11 | 2588 | 1.445 | 0.4642 | Yes | ||
| 26 | HMGCS1 | ENSG00000112972.15 | 2715 | 1.404 | 0.4757 | Yes | ||
| 27 | PPARG | ENSG00000132170.21 | 2883 | 1.360 | 0.4858 | Yes | ||
| 28 | NFIL3 | ENSG00000165030.4 | 2885 | 1.360 | 0.4997 | Yes | ||
| 29 | GPX8 | ENSG00000164294.14 | 3019 | 1.329 | 0.5103 | Yes | ||
| 30 | SREBF2 | ENSG00000198911.12 | 3043 | 1.323 | 0.5233 | Yes | ||
| 31 | LPL | ENSG00000175445.17 | 3048 | 1.322 | 0.5368 | Yes | ||
| 32 | FASN | ENSG00000169710.9 | 3072 | 1.316 | 0.5498 | Yes | ||
| 33 | MVD | ENSG00000167508.12 | 3276 | 1.273 | 0.5581 | Yes | ||
| 34 | FDPS | ENSG00000160752.14 | 3502 | 1.225 | 0.5655 | Yes | ||
| 35 | GUSB | ENSG00000169919.17 | 3543 | 1.217 | 0.5771 | Yes | ||
| 36 | STARD4 | ENSG00000164211.13 | 3550 | 1.216 | 0.5894 | Yes | ||
| 37 | DHCR7 | ENSG00000172893.15 | 3663 | 1.193 | 0.5990 | Yes | ||
| 38 | FDFT1 | ENSG00000079459.13 | 3715 | 1.180 | 0.6100 | Yes | ||
| 39 | TMEM97 | ENSG00000109084.14 | 3999 | 1.128 | 0.6150 | Yes | ||
| 40 | SEMA3B | ENSG00000012171.20 | 4765 | 1.004 | 0.6075 | Yes | ||
| 41 | ANXA5 | ENSG00000164111.15 | 5451 | 0.906 | 0.6009 | Yes | ||
| 42 | GNAI1 | ENSG00000127955.17 | 5889 | 0.854 | 0.5995 | Yes | ||
| 43 | STX5 | ENSG00000162236.12 | 5994 | 0.842 | 0.6058 | Yes | ||
| 44 | TM7SF2 | ENSG00000149809.15 | 6196 | 0.817 | 0.6095 | Yes | ||
| 45 | CHKA | ENSG00000110721.12 | 6358 | 0.801 | 0.6140 | Yes | ||
| 46 | MAL2 | ENSG00000147676.14 | 6795 | 0.758 | 0.6116 | Yes | ||
| 47 | FABP5 | ENSG00000164687.11 | 6871 | 0.750 | 0.6176 | Yes | ||
| 48 | NSDHL | ENSG00000147383.11 | 7604 | 0.679 | 0.6075 | No | ||
| 49 | AVPR1A | ENSG00000166148.3 | 8467 | 0.608 | 0.5938 | No | ||
| 50 | S100A11 | ENSG00000163191.6 | 8633 | 0.596 | 0.5960 | No | ||
| 51 | EBP | ENSG00000147155.11 | 9521 | 0.536 | 0.5809 | No | ||
| 52 | PDK3 | ENSG00000067992.15 | 16173 | 0.238 | 0.4289 | No | ||
| 53 | LGMN | ENSG00000100600.15 | 17960 | 0.148 | 0.3889 | No | ||
| 54 | IDI1 | ENSG00000067064.11 | 20014 | 0.048 | 0.3417 | No | ||
| 55 | ALCAM | ENSG00000170017.12 | 21952 | -0.054 | 0.2973 | No | ||
| 56 | CBS | ENSG00000160200.17 | 22418 | -0.080 | 0.2873 | No | ||
| 57 | TRIB3 | ENSG00000101255.11 | 23059 | -0.115 | 0.2736 | No | ||
| 58 | ATF3 | ENSG00000162772.17 | 25795 | -0.246 | 0.2126 | No | ||
| 59 | CPEB2 | ENSG00000137449.16 | 29525 | -0.376 | 0.1298 | No | ||
| 60 | ACTG1 | ENSG00000184009.12 | 30626 | -0.445 | 0.1088 | No | ||
| 61 | ECH1 | ENSG00000104823.9 | 33133 | -0.593 | 0.0567 | No | ||
| 62 | ATXN2 | ENSG00000204842.17 | 34246 | -0.678 | 0.0378 | No | ||
| 63 | SC5D | ENSG00000109929.10 | 34365 | -0.689 | 0.0422 | No | ||
| 64 | ANXA13 | ENSG00000104537.17 | 34543 | -0.706 | 0.0453 | No | ||
| 65 | JAG1 | ENSG00000101384.12 | 35655 | -0.804 | 0.0277 | No | ||
| 66 | PMVK | ENSG00000163344.6 | 36154 | -0.862 | 0.0250 | No | ||
| 67 | GLDC | ENSG00000178445.9 | 37681 | -1.063 | 0.0005 | No | ||
| 68 | ANTXR2 | ENSG00000163297.17 | 38577 | -1.219 | -0.0078 | No | ||
| 69 | ATF5 | ENSG00000169136.11 | 41134 | -1.925 | -0.0474 | No | ||
| 70 | PLAUR | ENSG00000011422.12 | 41170 | -1.945 | -0.0282 | No | ||
| 71 | TNFRSF12A | ENSG00000006327.13 | 41188 | -1.954 | -0.0086 | No | ||
| 72 | CTNNB1 | ENSG00000168036.18 | 41475 | -2.117 | 0.0065 | No | ||
| 73 | ERRFI1 | ENSG00000116285.13 | 42466 | -3.084 | 0.0152 | No |
