Details for gene set HALLMARK_COAGULATION[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2
GeneSet	HALLMARK_COAGULATION
Enrichment Score (ES)	0.4239292
Normalized Enrichment Score (NES)	1.804934
Nominal p-value	0.0
FDR q-value	8.7152555E-4
FWER p-Value	0.004

Fig 1: Enrichment plot: HALLMARK_COAGULATION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DPP4	ENSG00000197635.10			30	4.288	0.0259	Yes
2	C1S	ENSG00000182326.15			34	4.267	0.0523	Yes
3	CTSB	ENSG00000164733.21			145	3.504	0.0715	Yes
4	ANG	ENSG00000214274.9			174	3.361	0.0917	Yes
5	CFB	ENSG00000243649.8			196	3.306	0.1118	Yes
6	RGN	ENSG00000130988.13			200	3.302	0.1322	Yes
7	CTSK	ENSG00000143387.13			210	3.273	0.1523	Yes
8	C1R	ENSG00000159403.18			251	3.121	0.1708	Yes
9	ITGA2	ENSG00000164171.11			327	2.899	0.1870	Yes
10	ACOX2	ENSG00000168306.13			370	2.812	0.2035	Yes
11	RAPGEF3	ENSG00000079337.16			372	2.805	0.2209	Yes
12	TMPRSS6	ENSG00000187045.18			499	2.600	0.2341	Yes
13	TIMP1	ENSG00000102265.12			582	2.491	0.2476	Yes
14	CPQ	ENSG00000104324.16			721	2.349	0.2590	Yes
15	TIMP3	ENSG00000100234.11			892	2.178	0.2686	Yes
16	CTSO	ENSG00000256043.3			953	2.131	0.2804	Yes
17	PROS1	ENSG00000184500.15			997	2.107	0.2925	Yes
18	MAFF	ENSG00000185022.12			1086	2.057	0.3032	Yes
19	CAPN5	ENSG00000149260.18			1156	2.013	0.3141	Yes
20	P2RY1	ENSG00000169860.7			1233	1.973	0.3246	Yes
21	ISCU	ENSG00000136003.15			1254	1.961	0.3363	Yes
22	CD9	ENSG00000010278.14			1562	1.814	0.3404	Yes
23	DUSP6	ENSG00000139318.8			1611	1.795	0.3504	Yes
24	GNG12	ENSG00000172380.6			1804	1.714	0.3566	Yes
25	CFD	ENSG00000197766.8			1895	1.671	0.3649	Yes
26	TF	ENSG00000091513.16			1973	1.641	0.3733	Yes
27	CLU	ENSG00000120885.22			2415	1.500	0.3724	Yes
28	MMP1	ENSG00000196611.5			2473	1.481	0.3802	Yes
29	MMP3	ENSG00000149968.12			2562	1.453	0.3872	Yes
30	MMP2	ENSG00000087245.13			2616	1.437	0.3949	Yes
31	MST1	ENSG00000173531.15			2650	1.426	0.4030	Yes
32	C8G	ENSG00000176919.13			2959	1.343	0.4041	Yes
33	LRP1	ENSG00000123384.14			3000	1.333	0.4115	Yes
34	SERPING1	ENSG00000149131.15			3087	1.313	0.4176	Yes
35	MASP2	ENSG00000009724.17			3469	1.231	0.4164	Yes
36	VWF	ENSG00000110799.13			3693	1.186	0.4186	Yes
37	THBS1	ENSG00000137801.11			4127	1.107	0.4154	Yes
38	C3	ENSG00000125730.17			4292	1.078	0.4183	Yes
39	MMP10	ENSG00000166670.10			4529	1.040	0.4192	Yes
40	F10	ENSG00000126218.12			4837	0.991	0.4182	Yes
41	SERPINB2	ENSG00000197632.9			4983	0.970	0.4209	Yes
42	GP1BA	ENSG00000185245.8			5108	0.953	0.4239	Yes
43	FBN1	ENSG00000166147.13			5850	0.858	0.4120	No
44	COMP	ENSG00000105664.11			6225	0.814	0.4084	No
45	MMP8	ENSG00000118113.12			6665	0.771	0.4029	No
46	OLR1	ENSG00000173391.9			7038	0.734	0.3988	No
47	TFPI2	ENSG00000105825.14			7157	0.723	0.4006	No
48	F8	ENSG00000185010.15			7356	0.705	0.4004	No
49	S100A13	ENSG00000189171.14			7420	0.698	0.4032	No
50	F2RL2	ENSG00000164220.7			7910	0.654	0.3959	No
51	PEF1	ENSG00000162517.13			8174	0.631	0.3937	No
52	CFH	ENSG00000000971.15			8408	0.612	0.3921	No
53	MMP7	ENSG00000137673.9			8697	0.591	0.3891	No
54	PRSS23	ENSG00000150687.12			8732	0.588	0.3919	No
55	S100A1	ENSG00000160678.11			9481	0.539	0.3779	No
56	MMP14	ENSG00000157227.13			9489	0.539	0.3811	No
57	KLKB1	ENSG00000164344.16			9496	0.538	0.3843	No
58	FGA	ENSG00000171560.16			9683	0.524	0.3832	No
59	FN1	ENSG00000115414.19			9913	0.516	0.3811	No
60	ITIH1	ENSG00000055957.11			10626	0.470	0.3674	No
61	C2	ENSG00000166278.15			10689	0.466	0.3689	No
62	ARF4	ENSG00000168374.11			11127	0.437	0.3614	No
63	F3	ENSG00000117525.14			11227	0.431	0.3618	No
64	PLG	ENSG00000122194.18			11880	0.394	0.3491	No
65	CAPN2	ENSG00000162909.18			12007	0.388	0.3485	No
66	ANXA1	ENSG00000135046.14			12384	0.370	0.3421	No
67	MBL2	ENSG00000165471.6			13582	0.322	0.3162	No
68	GDA	ENSG00000119125.16			14105	0.311	0.3060	No
69	C8A	ENSG00000157131.10			14876	0.287	0.2899	No
70	ADAM9	ENSG00000168615.12			15364	0.282	0.2803	No
71	HPN	ENSG00000105707.14			15619	0.269	0.2761	No
72	LAMP2	ENSG00000005893.15			16244	0.233	0.2630	No
73	RABIF	ENSG00000183155.5			16494	0.220	0.2586	No
74	RAC1	ENSG00000136238.18			16886	0.203	0.2507	No
75	PLEK	ENSG00000115956.10			17299	0.183	0.2423	No
76	LTA4H	ENSG00000111144.10			17667	0.165	0.2348	No
77	LGMN	ENSG00000100600.15			17960	0.148	0.2289	No
78	C8B	ENSG00000021852.13			18843	0.105	0.2090	No
79	PROC	ENSG00000115718.17			18885	0.104	0.2087	No
80	GNB2	ENSG00000172354.10			19396	0.077	0.1973	No
81	HRG	ENSG00000113905.4			20309	0.031	0.1763	No
82	MMP11	ENSG00000099953.10			20933	-0.001	0.1618	No
83	APOC2	ENSG00000234906.10			21160	-0.014	0.1567	No
84	SERPINC1	ENSG00000117601.13			21552	-0.034	0.1478	No
85	A2M	ENSG00000175899.14			21664	-0.040	0.1454	No
86	FGG	ENSG00000171557.17			22680	-0.095	0.1224	No
87	FYN	ENSG00000010810.17			22887	-0.107	0.1183	No
88	PECAM1	ENSG00000261371.6			23502	-0.141	0.1049	No
89	HTRA1	ENSG00000166033.13			24116	-0.177	0.0917	No
90	DCT	ENSG00000080166.16			24780	-0.217	0.0777	No
91	HMGCS2	ENSG00000134240.11			24990	-0.223	0.0742	No
92	MSRB2	ENSG00000148450.13			25953	-0.258	0.0534	No
93	F13B	ENSG00000143278.4			26031	-0.262	0.0532	No
94	MEP1A	ENSG00000112818.10			26323	-0.263	0.0481	No
95	PROZ	ENSG00000126231.14			27498	-0.297	0.0226	No
96	F11	ENSG00000088926.13			28806	-0.351	-0.0056	No
97	C1QA	ENSG00000173372.17			28844	-0.351	-0.0043	No
98	APOC3	ENSG00000110245.12			29586	-0.380	-0.0192	No
99	F12	ENSG00000131187.9			29857	-0.394	-0.0230	No
100	HNF4A	ENSG00000101076.16			30407	-0.432	-0.0331	No
101	MMP9	ENSG00000100985.7			31139	-0.471	-0.0472	No
102	ITGB3	ENSG00000259207.7			31330	-0.481	-0.0486	No
103	CPB2	ENSG00000080618.16			32522	-0.544	-0.0729	No
104	GSN	ENSG00000148180.19			32592	-0.551	-0.0711	No
105	DUSP14	ENSG00000276023.5			32940	-0.578	-0.0756	No
106	APOC1	ENSG00000130208.9			33251	-0.601	-0.0791	No
107	LEFTY2	ENSG00000143768.13			34745	-0.720	-0.1093	No
108	PF4	ENSG00000163737.4			34978	-0.739	-0.1101	No
109	C9	ENSG00000113600.11			35681	-0.807	-0.1215	No
110	GP9	ENSG00000169704.4			36202	-0.868	-0.1282	No
111	SPARC	ENSG00000113140.11			37052	-0.974	-0.1419	No
112	PREP	ENSG00000085377.14			37237	-0.997	-0.1400	No
113	FURIN	ENSG00000140564.12			37563	-1.044	-0.1410	No
114	SERPINE1	ENSG00000106366.8			38403	-1.189	-0.1532	No
115	BMP1	ENSG00000168487.19			39505	-1.423	-0.1700	No
116	KLF7	ENSG00000118263.15			39515	-1.424	-0.1613	No
117	CASP9	ENSG00000132906.18			39565	-1.434	-0.1536	No
118	WDR1	ENSG00000071127.17			39815	-1.497	-0.1501	No
119	THBD	ENSG00000178726.6			39927	-1.529	-0.1431	No
120	CFI	ENSG00000205403.13			40164	-1.591	-0.1388	No
121	CTSH	ENSG00000103811.16			40296	-1.626	-0.1317	No
122	CSRP1	ENSG00000159176.14			40304	-1.628	-0.1218	No
123	USP11	ENSG00000102226.9			40376	-1.650	-0.1132	No
124	SERPINA1	ENSG00000197249.13			40558	-1.704	-0.1068	No
125	CTSV	ENSG00000136943.11			41043	-1.887	-0.1064	No
126	APOA1	ENSG00000118137.9			41195	-1.956	-0.0977	No
127	MMP15	ENSG00000102996.5			41275	-1.992	-0.0872	No
128	PLAT	ENSG00000104368.18			41640	-2.216	-0.0819	No
129	F2	ENSG00000180210.14			41777	-2.308	-0.0707	No
130	PDGFB	ENSG00000100311.17			41932	-2.434	-0.0592	No
131	SIRT2	ENSG00000068903.20			42338	-2.901	-0.0506	No
132	PLAU	ENSG00000122861.16			42698	-3.591	-0.0367	No
133	SH2B2	ENSG00000160999.10			42724	-3.659	-0.0146	No
134	CRIP2	ENSG00000182809.10			42778	-3.821	0.0079	No

Fig 2: HALLMARK_COAGULATION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_COAGULATION: Random ES distribution   
Gene set null distribution of ES for HALLMARK_COAGULATION