Details for gene set HALLMARK

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2
GeneSet	HALLMARK_COMPLEMENT
Enrichment Score (ES)	0.3629188
Normalized Enrichment Score (NES)	1.6337557
Nominal p-value	0.0
FDR q-value	0.006208492
FWER p-Value	0.033

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CASP10	ENSG00000003400.14	10	4.582	0.0184	Yes
2	DPP4	ENSG00000197635.10	30	4.288	0.0355	Yes
3	C1S	ENSG00000182326.15	34	4.267	0.0528	Yes
4	KCNIP3	ENSG00000115041.13	68	3.944	0.0681	Yes
5	CTSB	ENSG00000164733.21	145	3.504	0.0806	Yes
6	LGALS3	ENSG00000131981.16	150	3.486	0.0948	Yes
7	ANG	ENSG00000214274.9	174	3.361	0.1079	Yes
8	CFB	ENSG00000243649.8	196	3.306	0.1209	Yes
9	C1R	ENSG00000159403.18	251	3.121	0.1324	Yes
10	PRCP	ENSG00000137509.11	377	2.794	0.1409	Yes
11	TIMP2	ENSG00000035862.12	402	2.753	0.1515	Yes
12	APOBEC3F	ENSG00000128394.17	410	2.739	0.1625	Yes
13	CTSS	ENSG00000163131.11	442	2.687	0.1728	Yes
14	CTSL	ENSG00000135047.15	458	2.665	0.1833	Yes
15	TMPRSS6	ENSG00000187045.18	499	2.600	0.1929	Yes
16	LIPA	ENSG00000107798.18	528	2.571	0.2028	Yes
17	TIMP1	ENSG00000102265.12	582	2.491	0.2117	Yes
18	PSMB9	ENSG00000240065.8	653	2.409	0.2199	Yes
19	CPQ	ENSG00000104324.16	721	2.349	0.2279	Yes
20	PRSS36	ENSG00000178226.11	819	2.244	0.2348	Yes
21	APOBEC3G	ENSG00000239713.9	876	2.186	0.2424	Yes
22	CTSO	ENSG00000256043.3	953	2.131	0.2493	Yes
23	CALM3	ENSG00000160014.17	958	2.130	0.2579	Yes
24	PLSCR1	ENSG00000188313.13	1031	2.090	0.2647	Yes
25	MAFF	ENSG00000185022.12	1086	2.057	0.2719	Yes
26	SRC	ENSG00000197122.11	1168	2.008	0.2782	Yes
27	CEBPB	ENSG00000172216.6	1238	1.972	0.2846	Yes
28	CD46	ENSG00000117335.19	1590	1.805	0.2838	Yes
29	CP	ENSG00000047457.14	1593	1.802	0.2911	Yes
30	DUSP6	ENSG00000139318.8	1611	1.795	0.2980	Yes
31	CD59	ENSG00000085063.16	1662	1.770	0.3041	Yes
32	DUSP5	ENSG00000138166.6	1674	1.764	0.3110	Yes
33	IRF2	ENSG00000168310.11	1700	1.754	0.3176	Yes
34	CASP5	ENSG00000137757.11	2183	1.572	0.3127	Yes
35	CD36	ENSG00000135218.19	2200	1.566	0.3188	Yes
36	CASP4	ENSG00000196954.14	2254	1.548	0.3238	Yes
37	CLU	ENSG00000120885.22	2415	1.500	0.3262	Yes
38	RHOG	ENSG00000177105.10	2462	1.485	0.3312	Yes
39	CPM	ENSG00000135678.12	2638	1.429	0.3330	Yes
40	CASP1	ENSG00000137752.24	2840	1.369	0.3339	Yes
41	LRP1	ENSG00000123384.14	3000	1.333	0.3356	Yes
42	SERPING1	ENSG00000149131.15	3087	1.313	0.3389	Yes
43	RASGRP1	ENSG00000172575.12	3180	1.292	0.3421	Yes
44	DOCK4	ENSG00000128512.22	3363	1.252	0.3429	Yes
45	PRSS3	ENSG00000010438.16	3403	1.245	0.3471	Yes
46	IRF1	ENSG00000125347.14	3458	1.235	0.3509	Yes
47	PHEX	ENSG00000102174.9	3561	1.215	0.3534	Yes
48	PCSK9	ENSG00000169174.10	3586	1.208	0.3578	Yes
49	GPD2	ENSG00000115159.16	3791	1.167	0.3578	Yes
50	PDP1	ENSG00000164951.16	3884	1.148	0.3604	Yes
51	C3	ENSG00000125730.17	4292	1.078	0.3553	Yes
52	F10	ENSG00000126218.12	4837	0.991	0.3466	Yes
53	SERPINB2	ENSG00000197632.9	4983	0.970	0.3472	Yes
54	CR1	ENSG00000203710.11	5061	0.959	0.3493	Yes
55	GNAI2	ENSG00000114353.17	5091	0.956	0.3526	Yes
56	GP1BA	ENSG00000185245.8	5108	0.953	0.3561	Yes
57	CD55	ENSG00000196352.15	5115	0.952	0.3598	Yes
58	DOCK10	ENSG00000135905.19	5321	0.924	0.3588	Yes
59	ANXA5	ENSG00000164111.15	5451	0.906	0.3595	Yes
60	AC016586.1	ENSG00000268670.1	5463	0.904	0.3629	Yes
61	PRKCD	ENSG00000163932.15	5863	0.856	0.3571	No
62	FDX1	ENSG00000137714.3	5937	0.849	0.3589	No
63	PLA2G4A	ENSG00000116711.10	6498	0.788	0.3490	No
64	NOTCH4	ENSG00000204301.6	6513	0.787	0.3519	No
65	MMP8	ENSG00000118113.12	6665	0.771	0.3515	No
66	CDA	ENSG00000158825.6	6850	0.752	0.3503	No
67	OLR1	ENSG00000173391.9	7038	0.734	0.3490	No
68	TFPI2	ENSG00000105825.14	7157	0.723	0.3492	No
69	KYNU	ENSG00000115919.15	7285	0.711	0.3491	No
70	F8	ENSG00000185010.15	7356	0.705	0.3503	No
71	S100A13	ENSG00000189171.14	7420	0.698	0.3517	No
72	GNAI3	ENSG00000065135.11	7451	0.695	0.3539	No
73	CTSC	ENSG00000109861.16	7476	0.693	0.3561	No
74	C4BPB	ENSG00000123843.13	7483	0.692	0.3588	No
75	ATOX1	ENSG00000177556.12	7840	0.661	0.3532	No
76	DGKH	ENSG00000102780.16	7915	0.654	0.3541	No
77	CFH	ENSG00000000971.15	8408	0.612	0.3452	No
78	FCN1	ENSG00000085265.11	8484	0.608	0.3459	No
79	CCL5	ENSG00000271503.6	8798	0.583	0.3410	No
80	HSPA1A	ENSG00000204389.10	8966	0.570	0.3394	No
81	SH2B3	ENSG00000111252.10	9235	0.553	0.3354	No
82	MMP14	ENSG00000157227.13	9489	0.539	0.3317	No
83	KLKB1	ENSG00000164344.16	9496	0.538	0.3338	No
84	FN1	ENSG00000115414.19	9913	0.516	0.3262	No
85	F7	ENSG00000057593.13	10063	0.507	0.3248	No
86	ITIH1	ENSG00000055957.11	10626	0.470	0.3136	No
87	C2	ENSG00000166278.15	10689	0.466	0.3141	No
88	LYN	ENSG00000254087.8	10784	0.460	0.3138	No
89	LCP2	ENSG00000043462.12	11106	0.438	0.3081	No
90	VCPIP1	ENSG00000175073.8	11186	0.433	0.3080	No
91	F3	ENSG00000117525.14	11227	0.431	0.3088	No
92	GCA	ENSG00000115271.11	11596	0.408	0.3019	No
93	USP8	ENSG00000138592.14	11662	0.404	0.3020	No
94	PLG	ENSG00000122194.18	11880	0.394	0.2986	No
95	AKAP10	ENSG00000108599.15	12100	0.382	0.2950	No
96	ERAP2	ENSG00000164308.16	12335	0.373	0.2911	No
97	IRF7	ENSG00000185507.21	14110	0.311	0.2511	No
98	RNF4	ENSG00000063978.16	14118	0.310	0.2522	No
99	ADAM9	ENSG00000168615.12	15364	0.282	0.2243	No
100	LCK	ENSG00000182866.17	15496	0.275	0.2224	No
101	LAMP2	ENSG00000005893.15	16244	0.233	0.2059	No
102	KLK1	ENSG00000167748.11	16260	0.232	0.2065	No
103	GNB4	ENSG00000114450.10	16478	0.221	0.2024	No
104	RABIF	ENSG00000183155.5	16494	0.220	0.2029	No
105	WAS	ENSG00000015285.10	16612	0.214	0.2010	No
106	PIM1	ENSG00000137193.14	16645	0.213	0.2012	No
107	CXCL1	ENSG00000163739.5	17045	0.196	0.1927	No
108	PLEK	ENSG00000115956.10	17299	0.183	0.1875	No
109	CD40LG	ENSG00000102245.7	17639	0.167	0.1803	No
110	LTA4H	ENSG00000111144.10	17667	0.165	0.1804	No
111	PLA2G7	ENSG00000146070.17	17722	0.162	0.1798	No
112	LGMN	ENSG00000100600.15	17960	0.148	0.1748	No
113	RBSN	ENSG00000131381.12	18086	0.142	0.1725	No
114	CTSD	ENSG00000117984.14	18089	0.141	0.1730	No
115	MMP12	ENSG00000262406.3	18315	0.129	0.1683	No
116	PRDM4	ENSG00000110851.12	19123	0.093	0.1499	No
117	GNB2	ENSG00000172354.10	19396	0.077	0.1439	No
118	RCE1	ENSG00000173653.8	19938	0.051	0.1315	No
119	PIK3CA	ENSG00000121879.5	19940	0.051	0.1317	No
120	PSEN1	ENSG00000080815.19	20272	0.034	0.1241	No
121	GZMK	ENSG00000113088.6	20474	0.024	0.1195	No
122	SERPINC1	ENSG00000117601.13	21552	-0.034	0.0945	No
123	FYN	ENSG00000010810.17	22887	-0.107	0.0639	No
124	CASP7	ENSG00000165806.20	23029	-0.113	0.0611	No
125	STX4	ENSG00000103496.15	23081	-0.117	0.0604	No
126	GNG2	ENSG00000186469.8	23173	-0.123	0.0588	No
127	PIK3R5	ENSG00000141506.13	23567	-0.145	0.0502	No
128	PPP4C	ENSG00000149923.14	23997	-0.171	0.0409	No
129	F5	ENSG00000198734.11	24021	-0.173	0.0411	No
130	SCG3	ENSG00000104112.9	24442	-0.195	0.0321	No
131	GZMA	ENSG00000145649.8	25202	-0.223	0.0153	No
132	BRPF3	ENSG00000096070.19	27141	-0.283	-0.0287	No
133	APOA4	ENSG00000110244.7	27731	-0.302	-0.0412	No
134	GMFB	ENSG00000197045.13	28527	-0.338	-0.0583	No
135	C1QA	ENSG00000173372.17	28844	-0.351	-0.0643	No
136	L3MBTL4	ENSG00000154655.15	29264	-0.360	-0.0726	No
137	LAP3	ENSG00000002549.12	29880	-0.396	-0.0853	No
138	HNF4A	ENSG00000101076.16	30407	-0.432	-0.0958	No
139	CR2	ENSG00000117322.17	31514	-0.489	-0.1195	No
140	GATA3	ENSG00000107485.18	31550	-0.493	-0.1183	No
141	JAK2	ENSG00000096968.13	31758	-0.501	-0.1211	No
142	RAF1	ENSG00000132155.11	32694	-0.559	-0.1406	No
143	SPOCK2	ENSG00000107742.13	32816	-0.570	-0.1411	No
144	APOC1	ENSG00000130208.9	33251	-0.601	-0.1488	No
145	USP16	ENSG00000156256.15	33872	-0.651	-0.1606	No
146	PPP2CB	ENSG00000104695.13	34925	-0.735	-0.1821	No
147	GZMB	ENSG00000100453.13	35349	-0.772	-0.1888	No
148	CBLB	ENSG00000114423.22	35351	-0.773	-0.1857	No
149	USP15	ENSG00000135655.16	35611	-0.799	-0.1884	No
150	C9	ENSG00000113600.11	35681	-0.807	-0.1868	No
151	KCNIP2	ENSG00000120049.19	36062	-0.851	-0.1921	No
152	GP9	ENSG00000169704.4	36202	-0.868	-0.1918	No
153	CA2	ENSG00000104267.10	36626	-0.919	-0.1979	No
154	MT3	ENSG00000087250.8	36936	-0.957	-0.2012	No
155	PREP	ENSG00000085377.14	37237	-0.997	-0.2042	No
156	IL6	ENSG00000136244.12	37366	-1.015	-0.2030	No
157	PIK3CG	ENSG00000105851.11	37680	-1.063	-0.2060	No
158	EHD1	ENSG00000110047.18	37992	-1.116	-0.2087	No
159	ZEB1	ENSG00000148516.21	38269	-1.166	-0.2103	No
160	SERPINE1	ENSG00000106366.8	38403	-1.189	-0.2086	No
161	MSRB1	ENSG00000198736.11	38437	-1.196	-0.2045	No
162	HPCAL4	ENSG00000116983.13	38464	-1.199	-0.2002	No
163	PCLO	ENSG00000186472.20	38753	-1.255	-0.2018	No
164	GRB2	ENSG00000177885.15	39308	-1.380	-0.2091	No
165	ME1	ENSG00000065833.9	39319	-1.382	-0.2037	No
166	XPNPEP1	ENSG00000108039.18	39332	-1.384	-0.1983	No
167	TNFAIP3	ENSG00000118503.15	39359	-1.390	-0.1933	No
168	COL4A2	ENSG00000134871.19	39460	-1.413	-0.1898	No
169	CASP9	ENSG00000132906.18	39565	-1.434	-0.1864	No
170	USP14	ENSG00000101557.15	39871	-1.514	-0.1873	No
171	PFN1	ENSG00000108518.7	40055	-1.560	-0.1852	No
172	CTSH	ENSG00000103811.16	40296	-1.626	-0.1842	No
173	CSRP1	ENSG00000159176.14	40304	-1.628	-0.1777	No
174	LTF	ENSG00000012223.13	40415	-1.661	-0.1735	No
175	KIF2A	ENSG00000068796.16	40453	-1.672	-0.1676	No
176	ADRA2B	ENSG00000274286.2	40474	-1.681	-0.1612	No
177	SERPINA1	ENSG00000197249.13	40558	-1.704	-0.1562	No
178	ITGAM	ENSG00000169896.18	40880	-1.815	-0.1562	No
179	CTSV	ENSG00000136943.11	41043	-1.887	-0.1523	No
180	ZFPM2	ENSG00000169946.14	41138	-1.926	-0.1467	No
181	CDH13	ENSG00000140945.17	41157	-1.936	-0.1392	No
182	PLAUR	ENSG00000011422.12	41170	-1.945	-0.1315	No
183	MMP15	ENSG00000102996.5	41275	-1.992	-0.1258	No
184	MMP13	ENSG00000137745.12	41348	-2.033	-0.1192	No
185	DYRK2	ENSG00000127334.10	41627	-2.208	-0.1167	No
186	PLAT	ENSG00000104368.18	41640	-2.216	-0.1079	No
187	HSPA5	ENSG00000044574.8	41668	-2.232	-0.0995	No
188	F2	ENSG00000180210.14	41777	-2.308	-0.0926	No
189	PDGFB	ENSG00000100311.17	41932	-2.434	-0.0862	No
190	GNGT2	ENSG00000167083.7	42221	-2.737	-0.0818	No
191	FCER1G	ENSG00000158869.11	42299	-2.847	-0.0720	No
192	CASP3	ENSG00000164305.19	42313	-2.869	-0.0606	No
193	CALM1	ENSG00000198668.12	42323	-2.877	-0.0491	No
194	DOCK9	ENSG00000088387.19	42425	-3.027	-0.0391	No
195	CDK5R1	ENSG00000176749.9	42942	-4.486	-0.0328	No
196	DGKG	ENSG00000058866.15	42945	-4.495	-0.0145	No
197	ACTN2	ENSG00000077522.13	42966	-4.553	0.0036	No