Details for gene set HALLMARK_ESTROGEN_RESPONSE_LATE[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2
GeneSet	HALLMARK_ESTROGEN_RESPONSE_LATE
Enrichment Score (ES)	0.3217897
Normalized Enrichment Score (NES)	1.4546726
Nominal p-value	0.0037453184
FDR q-value	0.025801698
FWER p-Value	0.163

Fig 1: Enrichment plot: HALLMARK_ESTROGEN_RESPONSE_LATE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NBL1	ENSG00000158747.14			142	3.516	0.0111	Yes
2	IGFBP4	ENSG00000141753.7			151	3.478	0.0252	Yes
3	CD44	ENSG00000026508.18			157	3.446	0.0392	Yes
4	SCNN1A	ENSG00000111319.13			172	3.375	0.0526	Yes
5	FAM102A	ENSG00000167106.12			222	3.245	0.0648	Yes
6	PGR	ENSG00000082175.15			256	3.111	0.0768	Yes
7	IL6ST	ENSG00000134352.20			282	3.044	0.0887	Yes
8	TPBG	ENSG00000146242.8			331	2.893	0.0994	Yes
9	ZFP36	ENSG00000128016.7			348	2.862	0.1107	Yes
10	BCL2	ENSG00000171791.13			349	2.862	0.1225	Yes
11	PERP	ENSG00000112378.12			350	2.857	0.1342	Yes
12	ACOX2	ENSG00000168306.13			370	2.812	0.1452	Yes
13	KLF4	ENSG00000136826.15			421	2.729	0.1552	Yes
14	ADD3	ENSG00000148700.15			598	2.472	0.1613	Yes
15	ATP2B4	ENSG00000058668.14			627	2.432	0.1706	Yes
16	CYP26B1	ENSG00000003137.8			683	2.377	0.1790	Yes
17	MICB	ENSG00000204516.10			794	2.266	0.1857	Yes
18	OLFM1	ENSG00000130558.19			825	2.239	0.1942	Yes
19	ALDH3A2	ENSG00000072210.19			840	2.223	0.2030	Yes
20	CISH	ENSG00000114737.15			1052	2.083	0.2066	Yes
21	RPS6KA2	ENSG00000071242.12			1099	2.049	0.2139	Yes
22	MAPK13	ENSG00000156711.17			1253	1.961	0.2184	Yes
23	PDCD4	ENSG00000150593.18			1417	1.879	0.2223	Yes
24	EGR3	ENSG00000179388.9			1551	1.818	0.2266	Yes
25	CD9	ENSG00000010278.14			1562	1.814	0.2338	Yes
26	BLVRB	ENSG00000090013.11			1648	1.782	0.2392	Yes
27	PAPSS2	ENSG00000198682.13			1705	1.753	0.2450	Yes
28	CXCL12	ENSG00000107562.16			1796	1.720	0.2500	Yes
29	KRT19	ENSG00000171345.13			1802	1.716	0.2569	Yes
30	TJP3	ENSG00000105289.15			1957	1.648	0.2601	Yes
31	MAPT	ENSG00000186868.15			2157	1.580	0.2619	Yes
32	CCN5	ENSG00000064205.10			2260	1.545	0.2659	Yes
33	PRKAR2B	ENSG00000005249.13			2294	1.537	0.2714	Yes
34	NAB2	ENSG00000166886.13			2304	1.534	0.2774	Yes
35	PPIF	ENSG00000108179.14			2376	1.511	0.2820	Yes
36	IL17RB	ENSG00000056736.10			2614	1.438	0.2824	Yes
37	CAV1	ENSG00000105974.12			2696	1.410	0.2862	Yes
38	AFF1	ENSG00000172493.20			2700	1.409	0.2919	Yes
39	CPE	ENSG00000109472.14			2910	1.353	0.2926	Yes
40	PTGER3	ENSG00000050628.20			3014	1.330	0.2957	Yes
41	CA12	ENSG00000074410.14			3104	1.310	0.2990	Yes
42	ISG20	ENSG00000172183.15			3169	1.296	0.3028	Yes
43	SCARB1	ENSG00000073060.16			3609	1.204	0.2975	Yes
44	DHCR7	ENSG00000172893.15			3663	1.193	0.3011	Yes
45	FDFT1	ENSG00000079459.13			3715	1.180	0.3048	Yes
46	CACNA2D2	ENSG00000007402.11			3855	1.154	0.3063	Yes
47	ELOVL5	ENSG00000012660.14			3930	1.140	0.3092	Yes
48	UGDH	ENSG00000109814.12			3997	1.129	0.3123	Yes
49	DNAJC1	ENSG00000136770.11			4342	1.070	0.3087	Yes
50	PTGES	ENSG00000148344.11			4412	1.060	0.3114	Yes
51	SGK1	ENSG00000118515.11			4450	1.052	0.3148	Yes
52	CCND1	ENSG00000110092.3			4717	1.011	0.3128	Yes
53	SEMA3B	ENSG00000012171.20			4765	1.004	0.3158	Yes
54	MDK	ENSG00000110492.15			5041	0.962	0.3133	Yes
55	FOXC1	ENSG00000054598.9			5058	0.960	0.3169	Yes
56	CXCL14	ENSG00000145824.12			5106	0.953	0.3197	Yes
57	PRLR	ENSG00000113494.17			5183	0.942	0.3218	Yes
58	GLA	ENSG00000102393.10			5414	0.912	0.3202	No
59	GAL	ENSG00000069482.7			5666	0.880	0.3179	No
60	GPER1	ENSG00000164850.15			6050	0.836	0.3124	No
61	RAB31	ENSG00000168461.13			6077	0.831	0.3152	No
62	TFAP2C	ENSG00000087510.7			6149	0.822	0.3169	No
63	ITPK1	ENSG00000100605.17			6290	0.807	0.3170	No
64	ST14	ENSG00000149418.11			6638	0.774	0.3121	No
65	FABP5	ENSG00000164687.11			6871	0.750	0.3097	No
66	ASS1	ENSG00000130707.18			7046	0.733	0.3087	No
67	TFPI2	ENSG00000105825.14			7157	0.723	0.3091	No
68	FARP1	ENSG00000152767.17			7828	0.661	0.2962	No
69	SCUBE2	ENSG00000175356.13			7929	0.652	0.2965	No
70	ST6GALNAC2	ENSG00000070731.11			7997	0.647	0.2976	No
71	TRIM29	ENSG00000137699.17			8376	0.614	0.2913	No
72	PRSS23	ENSG00000150687.12			8732	0.588	0.2855	No
73	SULT2B1	ENSG00000088002.11			8911	0.575	0.2837	No
74	SNX10	ENSG00000086300.15			9608	0.529	0.2696	No
75	TST	ENSG00000128311.14			9625	0.528	0.2714	No
76	HSPA4L	ENSG00000164070.12			9659	0.525	0.2728	No
77	FOS	ENSG00000170345.10			9664	0.525	0.2749	No
78	DLG5	ENSG00000151208.17			10138	0.501	0.2659	No
79	PCP4	ENSG00000183036.11			11202	0.433	0.2429	No
80	ASCL1	ENSG00000139352.4			11422	0.419	0.2395	No
81	RET	ENSG00000165731.20			12408	0.369	0.2181	No
82	CALCR	ENSG00000004948.15			13124	0.350	0.2028	No
83	NMU	ENSG00000109255.11			13431	0.331	0.1971	No
84	IMPA2	ENSG00000141401.12			13538	0.324	0.1959	No
85	ALDH3B1	ENSG00000006534.16			14064	0.314	0.1850	No
86	BATF	ENSG00000156127.7			14541	0.308	0.1752	No
87	GJB3	ENSG00000188910.8			16113	0.242	0.1395	No
88	SLC2A8	ENSG00000136856.18			16130	0.241	0.1402	No
89	SERPINA3	ENSG00000196136.17			16370	0.226	0.1355	No
90	NPY1R	ENSG00000164128.7			16610	0.214	0.1308	No
91	LSR	ENSG00000105699.16			17054	0.196	0.1213	No
92	HR	ENSG00000168453.15			17070	0.194	0.1218	No
93	KLK10	ENSG00000129451.12			17579	0.170	0.1106	No
94	CHPT1	ENSG00000111666.11			17710	0.162	0.1083	No
95	TSTA3	ENSG00000104522.16			18779	0.108	0.0838	No
96	DCXR	ENSG00000169738.8			19340	0.081	0.0711	No
97	ID2	ENSG00000115738.10			19442	0.074	0.0690	No
98	JAK1	ENSG00000162434.13			19624	0.065	0.0651	No
99	ANXA9	ENSG00000143412.10			19674	0.062	0.0642	No
100	XRCC3	ENSG00000126215.14			19768	0.058	0.0623	No
101	TSPAN13	ENSG00000106537.8			20061	0.045	0.0557	No
102	KLK11	ENSG00000167757.14			20427	0.026	0.0473	No
103	MYOF	ENSG00000138119.17			20576	0.018	0.0439	No
104	BAG1	ENSG00000107262.23			21672	-0.041	0.0185	No
105	NXT1	ENSG00000132661.4			22966	-0.111	-0.0111	No
106	SIAH2	ENSG00000181788.4			23013	-0.113	-0.0117	No
107	CHST8	ENSG00000124302.13			23588	-0.146	-0.0245	No
108	WFS1	ENSG00000109501.13			23770	-0.155	-0.0281	No
109	SFN	ENSG00000175793.12			23845	-0.161	-0.0292	No
110	SOX3	ENSG00000134595.8			24382	-0.192	-0.0409	No
111	AMFR	ENSG00000159461.15			24485	-0.198	-0.0424	No
112	ETFB	ENSG00000105379.9			24745	-0.215	-0.0476	No
113	HMGCS2	ENSG00000134240.11			24990	-0.223	-0.0524	No
114	ARL3	ENSG00000138175.9			25638	-0.236	-0.0665	No
115	RBBP8	ENSG00000101773.19			26021	-0.261	-0.0743	No
116	OVOL2	ENSG00000125850.11			26280	-0.263	-0.0792	No
117	PLXNB1	ENSG00000164050.13			27135	-0.283	-0.0980	No
118	TPSAB1	ENSG00000172236.17			28979	-0.351	-0.1395	No
119	AREG	ENSG00000109321.11			29159	-0.357	-0.1422	No
120	SLC26A2	ENSG00000155850.7			29548	-0.377	-0.1497	No
121	KIF20A	ENSG00000112984.12			29750	-0.391	-0.1527	No
122	HPRT1	ENSG00000165704.15			29958	-0.404	-0.1559	No
123	RABEP1	ENSG00000029725.17			30408	-0.432	-0.1646	No
124	SLC27A2	ENSG00000140284.11			30591	-0.441	-0.1670	No
125	JAK2	ENSG00000096968.13			31758	-0.501	-0.1922	No
126	GINS2	ENSG00000131153.9			32126	-0.521	-0.1986	No
127	XBP1	ENSG00000100219.16			32221	-0.529	-0.1986	No
128	STIL	ENSG00000123473.15			32707	-0.560	-0.2076	No
129	FLNB	ENSG00000136068.14			32870	-0.574	-0.2090	No
130	MEST	ENSG00000106484.16			32879	-0.574	-0.2069	No
131	TH	ENSG00000180176.14			33344	-0.609	-0.2152	No
132	PLK4	ENSG00000142731.11			33445	-0.616	-0.2150	No
133	TOP2A	ENSG00000131747.15			33556	-0.624	-0.2150	No
134	SERPINA5	ENSG00000188488.14			33654	-0.635	-0.2146	No
135	KRT13	ENSG00000171401.15			34387	-0.691	-0.2289	No
136	KCNK5	ENSG00000164626.9			34538	-0.705	-0.2295	No
137	UNC13B	ENSG00000198722.14			34650	-0.714	-0.2291	No
138	CCNA1	ENSG00000133101.10			34815	-0.726	-0.2300	No
139	CYP4F11	ENSG00000171903.16			35089	-0.750	-0.2333	No
140	CLIC3	ENSG00000169583.13			35360	-0.774	-0.2364	No
141	DUSP2	ENSG00000158050.5			35482	-0.785	-0.2360	No
142	PKP3	ENSG00000184363.10			35564	-0.794	-0.2346	No
143	CDC20	ENSG00000117399.14			35877	-0.828	-0.2385	No
144	BTG3	ENSG00000154640.14			36393	-0.887	-0.2469	No
145	RAPGEFL1	ENSG00000108352.12			36612	-0.917	-0.2482	No
146	CA2	ENSG00000104267.10			36626	-0.919	-0.2447	No
147	AGR2	ENSG00000106541.12			36923	-0.956	-0.2477	No
148	DHRS2	ENSG00000100867.14			37225	-0.995	-0.2506	No
149	CDH1	ENSG00000039068.19			37235	-0.997	-0.2468	No
150	TOB1	ENSG00000141232.5			37303	-1.007	-0.2442	No
151	LAMC2	ENSG00000058085.15			37414	-1.022	-0.2426	No
152	LLGL2	ENSG00000073350.13			37508	-1.035	-0.2405	No
153	DYNLT3	ENSG00000165169.11			38084	-1.132	-0.2493	No
154	MOCS2	ENSG00000164172.19			38242	-1.161	-0.2482	No
155	IGSF1	ENSG00000147255.19			38251	-1.163	-0.2436	No
156	METTL3	ENSG00000165819.12			38364	-1.181	-0.2414	No
157	PTPN6	ENSG00000111679.17			38407	-1.189	-0.2375	No
158	PDZK1	ENSG00000174827.13			38667	-1.237	-0.2384	No
159	SORD	ENSG00000140263.14			38729	-1.249	-0.2347	No
160	TFF3	ENSG00000160180.15			39084	-1.327	-0.2376	No
161	PLAC1	ENSG00000170965.10			39219	-1.357	-0.2351	No
162	FGFR3	ENSG00000068078.18			39445	-1.408	-0.2346	No
163	SLC9A3R1	ENSG00000109062.12			39524	-1.426	-0.2306	No
164	COX6C	ENSG00000164919.11			39588	-1.439	-0.2261	No
165	OPN3	ENSG00000054277.14			39590	-1.440	-0.2203	No
166	MYB	ENSG00000118513.19			39639	-1.451	-0.2155	No
167	EMP2	ENSG00000213853.10			39656	-1.455	-0.2099	No
168	NRIP1	ENSG00000180530.11			39986	-1.544	-0.2112	No
169	FKBP5	ENSG00000096060.14			40021	-1.553	-0.2056	No
170	RNASEH2A	ENSG00000104889.6			40034	-1.556	-0.1995	No
171	SLC1A4	ENSG00000115902.11			40339	-1.639	-0.1999	No
172	LTF	ENSG00000012223.13			40415	-1.661	-0.1949	No
173	SERPINA1	ENSG00000197249.13			40558	-1.704	-0.1912	No
174	ABHD2	ENSG00000140526.18			40689	-1.746	-0.1871	No
175	FRK	ENSG00000111816.8			40827	-1.793	-0.1829	No
176	SLC22A5	ENSG00000197375.12			40836	-1.797	-0.1757	No
177	NCOR2	ENSG00000196498.13			40948	-1.842	-0.1708	No
178	LARGE1	ENSG00000133424.20			40958	-1.846	-0.1634	No
179	CELSR2	ENSG00000143126.8			41001	-1.869	-0.1567	No
180	TPD52L1	ENSG00000111907.21			41057	-1.891	-0.1503	No
181	CKB	ENSG00000166165.13			41077	-1.898	-0.1430	No
182	FKBP4	ENSG00000004478.8			41079	-1.899	-0.1352	No
183	SLC24A3	ENSG00000185052.12			41129	-1.924	-0.1285	No
184	GALE	ENSG00000117308.15			41501	-2.130	-0.1284	No
185	HOMER2	ENSG00000103942.13			41576	-2.179	-0.1212	No
186	CDC6	ENSG00000094804.12			41614	-2.200	-0.1130	No
187	DNAJC12	ENSG00000108176.15			41665	-2.231	-0.1051	No
188	SLC16A1	ENSG00000155380.11			41724	-2.273	-0.0971	No
189	ABCA3	ENSG00000167972.14			42113	-2.590	-0.0955	No
190	TIAM1	ENSG00000156299.13			42155	-2.641	-0.0857	No
191	PLAAT3	ENSG00000176485.11			42174	-2.666	-0.0752	No
192	SLC29A1	ENSG00000112759.18			42451	-3.060	-0.0691	No
193	IDH2	ENSG00000182054.9			42583	-3.291	-0.0586	No
194	SLC7A5	ENSG00000103257.9			42645	-3.449	-0.0459	No
195	HSPB8	ENSG00000152137.6			42810	-3.949	-0.0336	No
196	TNNC1	ENSG00000114854.8			43100	-4.968	-0.0200	No
197	PDLIM3	ENSG00000154553.15			43113	-4.975	0.0001	No

Fig 2: HALLMARK_ESTROGEN_RESPONSE_LATE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_ESTROGEN_RESPONSE_LATE: Random ES distribution   
Gene set null distribution of ES for HALLMARK_ESTROGEN_RESPONSE_LATE