Details for gene set HALLMARK_FATTY_ACID_METABOLISM[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2
GeneSet	HALLMARK_FATTY_ACID_METABOLISM
Enrichment Score (ES)	0.29541174
Normalized Enrichment Score (NES)	1.2947463
Nominal p-value	0.01992032
FDR q-value	0.0646152
FWER p-Value	0.52

Fig 1: Enrichment plot: HALLMARK_FATTY_ACID_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DHCR24	ENSG00000116133.13			91	3.768	0.0185	Yes
2	EPHX1	ENSG00000143819.12			223	3.237	0.0332	Yes
3	ACSS1	ENSG00000154930.15			241	3.164	0.0501	Yes
4	GLUL	ENSG00000135821.18			300	2.991	0.0651	Yes
5	UBE2L6	ENSG00000156587.16			391	2.767	0.0781	Yes
6	ADH1C	ENSG00000248144.6			760	2.300	0.0821	Yes
7	IDH1	ENSG00000138413.13			771	2.290	0.0944	Yes
8	CPT1A	ENSG00000110090.13			776	2.287	0.1069	Yes
9	ALDH3A2	ENSG00000072210.19			840	2.223	0.1175	Yes
10	ACAT2	ENSG00000120437.9			847	2.219	0.1295	Yes
11	CBR1	ENSG00000159228.13			964	2.124	0.1385	Yes
12	HAO2	ENSG00000116882.14			1276	1.954	0.1419	Yes
13	INMT	ENSG00000241644.2			1385	1.889	0.1497	Yes
14	CRAT	ENSG00000095321.17			1730	1.743	0.1513	Yes
15	AUH	ENSG00000148090.11			1776	1.726	0.1597	Yes
16	TDO2	ENSG00000151790.9			1817	1.707	0.1681	Yes
17	HSD17B7	ENSG00000132196.14			1994	1.633	0.1729	Yes
18	S100A10	ENSG00000197747.9			2097	1.600	0.1793	Yes
19	CBR3	ENSG00000159231.6			2198	1.567	0.1855	Yes
20	CD36	ENSG00000135218.19			2200	1.566	0.1941	Yes
21	ERP29	ENSG00000089248.7			2215	1.559	0.2023	Yes
22	IL4I1	ENSG00000104951.16			2235	1.554	0.2103	Yes
23	GABARAPL1	ENSG00000139112.11			2353	1.520	0.2159	Yes
24	HSD17B11	ENSG00000198189.11			2389	1.508	0.2234	Yes
25	PTPRG	ENSG00000144724.20			2683	1.414	0.2243	Yes
26	HMGCS1	ENSG00000112972.15			2715	1.404	0.2312	Yes
27	ACSL5	ENSG00000197142.10			2795	1.380	0.2370	Yes
28	MCEE	ENSG00000124370.11			2803	1.377	0.2443	Yes
29	AQP7	ENSG00000165269.13			3039	1.324	0.2461	Yes
30	FASN	ENSG00000169710.9			3072	1.316	0.2526	Yes
31	HPGD	ENSG00000164120.14			3099	1.310	0.2591	Yes
32	ACSM3	ENSG00000005187.12			3499	1.225	0.2565	Yes
33	SDHD	ENSG00000204370.12			3584	1.209	0.2612	Yes
34	AADAT	ENSG00000109576.14			3613	1.204	0.2671	Yes
35	GPD2	ENSG00000115159.16			3791	1.167	0.2694	Yes
36	ELOVL5	ENSG00000012660.14			3930	1.140	0.2724	Yes
37	UGDH	ENSG00000109814.12			3997	1.129	0.2771	Yes
38	PPARA	ENSG00000186951.16			4083	1.114	0.2812	Yes
39	GAPDHS	ENSG00000105679.9			4145	1.104	0.2858	Yes
40	LGALS1	ENSG00000100097.12			4241	1.085	0.2895	Yes
41	CPOX	ENSG00000080819.9			4313	1.075	0.2937	Yes
42	ALDH3A1	ENSG00000108602.18			4556	1.035	0.2938	Yes
43	CEL	ENSG00000170835.14			4724	1.010	0.2954	Yes
44	PCBD1	ENSG00000166228.9			4968	0.973	0.2951	No
45	HMGCL	ENSG00000117305.15			5503	0.900	0.2876	No
46	ALAD	ENSG00000148218.16			5811	0.863	0.2852	No
47	D2HGDH	ENSG00000180902.18			5888	0.854	0.2881	No
48	FMO1	ENSG00000010932.17			6346	0.803	0.2818	No
49	DLST	ENSG00000119689.15			6991	0.739	0.2709	No
50	NSDHL	ENSG00000147383.11			7604	0.679	0.2603	No
51	ACADS	ENSG00000122971.9			7993	0.648	0.2548	No
52	LTC4S	ENSG00000213316.10			8139	0.635	0.2549	No
53	ECI2	ENSG00000198721.12			8547	0.602	0.2488	No
54	REEP6	ENSG00000115255.11			8727	0.589	0.2478	No
55	CA6	ENSG00000131686.15			9732	0.522	0.2273	No
56	GAD2	ENSG00000136750.13			9849	0.520	0.2275	No
57	MGLL	ENSG00000074416.14			10076	0.505	0.2250	No
58	UROD	ENSG00000126088.14			10165	0.499	0.2256	No
59	SUCLG2	ENSG00000172340.14			10720	0.464	0.2153	No
60	ACAA1	ENSG00000060971.18			10861	0.454	0.2145	No
61	ALDH9A1	ENSG00000143149.12			11047	0.441	0.2126	No
62	RETSAT	ENSG00000042445.14			11072	0.439	0.2145	No
63	ADIPOR2	ENSG00000006831.10			11292	0.427	0.2117	No
64	ACOT8	ENSG00000101473.17			11383	0.422	0.2119	No
65	CRYZ	ENSG00000116791.14			11483	0.415	0.2119	No
66	NTHL1	ENSG00000065057.9			12537	0.363	0.1894	No
67	CYP4A22	ENSG00000162365.12			13803	0.322	0.1617	No
68	MLYCD	ENSG00000103150.7			15567	0.271	0.1221	No
69	BCKDHB	ENSG00000083123.15			16615	0.213	0.0989	No
70	VNN1	ENSG00000112299.8			16738	0.208	0.0972	No
71	ECI1	ENSG00000167969.13			17162	0.189	0.0884	No
72	IDH3G	ENSG00000067829.19			17636	0.167	0.0783	No
73	PSME1	ENSG00000092010.15			17744	0.161	0.0767	No
74	CIDEA	ENSG00000176194.18			18690	0.113	0.0553	No
75	ACOX1	ENSG00000161533.12			18902	0.103	0.0510	No
76	RDH16	ENSG00000139547.7			19139	0.093	0.0460	No
77	ACADVL	ENSG00000072778.20			19159	0.091	0.0460	No
78	IDI1	ENSG00000067064.11			20014	0.048	0.0264	No
79	OSTC	ENSG00000198856.13			20284	0.033	0.0203	No
80	BMPR1B	ENSG00000138696.11			22508	-0.085	-0.0309	No
81	PTS	ENSG00000150787.8			22993	-0.112	-0.0416	No
82	BLVRA	ENSG00000106605.11			23148	-0.121	-0.0445	No
83	LDHA	ENSG00000134333.14			23158	-0.122	-0.0441	No
84	NCAPH2	ENSG00000025770.19			23906	-0.165	-0.0605	No
85	RDH11	ENSG00000072042.13			23910	-0.166	-0.0597	No
86	HSD17B4	ENSG00000133835.16			24029	-0.173	-0.0615	No
87	SDHA	ENSG00000073578.17			24192	-0.182	-0.0643	No
88	HMGCS2	ENSG00000134240.11			24990	-0.223	-0.0816	No
89	ADH7	ENSG00000196344.11			25515	-0.228	-0.0926	No
90	YWHAH	ENSG00000128245.15			25599	-0.233	-0.0932	No
91	KMT5A	ENSG00000183955.13			26588	-0.273	-0.1147	No
92	SUCLG1	ENSG00000163541.12			28761	-0.349	-0.1634	No
93	MAOA	ENSG00000189221.9			29884	-0.397	-0.1873	No
94	HSDL2	ENSG00000119471.15			29975	-0.405	-0.1872	No
95	MIF	ENSG00000240972.2			30243	-0.424	-0.1911	No
96	H2AFZ	ENSG00000164032.12			30267	-0.427	-0.1893	No
97	SDHC	ENSG00000143252.14			30372	-0.429	-0.1894	No
98	XIST	ENSG00000229807.12			30632	-0.445	-0.1929	No
99	HADHB	ENSG00000138029.14			30755	-0.451	-0.1933	No
100	CYP1A1	ENSG00000140465.14			31019	-0.461	-0.1969	No
101	FABP2	ENSG00000145384.4			31826	-0.503	-0.2129	No
102	ETFDH	ENSG00000171503.12			32005	-0.514	-0.2143	No
103	IDH3B	ENSG00000101365.21			32024	-0.515	-0.2119	No
104	BPHL	ENSG00000137274.13			32864	-0.573	-0.2283	No
105	ECH1	ENSG00000104823.9			33133	-0.593	-0.2312	No
106	MDH1	ENSG00000014641.19			34029	-0.662	-0.2485	No
107	FH	ENSG00000091483.6			34076	-0.665	-0.2459	No
108	CCDC58	ENSG00000160124.9			34379	-0.691	-0.2491	No
109	SERINC1	ENSG00000111897.7			34417	-0.694	-0.2462	No
110	UROS	ENSG00000188690.15			35105	-0.751	-0.2581	No
111	APEX1	ENSG00000100823.12			35512	-0.788	-0.2632	No
112	HIBCH	ENSG00000198130.16			35612	-0.799	-0.2612	No
113	EHHADH	ENSG00000113790.11			36083	-0.853	-0.2674	No
114	NBN	ENSG00000104320.13			36600	-0.915	-0.2744	No
115	CA2	ENSG00000104267.10			36626	-0.919	-0.2700	No
116	METAP1	ENSG00000164024.12			36921	-0.956	-0.2716	No
117	GCDH	ENSG00000105607.13			37278	-1.003	-0.2744	No
118	CA4	ENSG00000167434.10			37287	-1.005	-0.2691	No
119	CPT2	ENSG00000157184.7			37417	-1.022	-0.2665	No
120	GSTZ1	ENSG00000100577.19			37706	-1.068	-0.2674	No
121	GRHPR	ENSG00000137106.18			37896	-1.100	-0.2657	No
122	ACOT2	ENSG00000119673.14			38194	-1.152	-0.2663	No
123	ALDOA	ENSG00000149925.20			38602	-1.223	-0.2691	No
124	HSP90AA1	ENSG00000080824.18			38879	-1.285	-0.2685	No
125	ACO2	ENSG00000100412.16			38900	-1.290	-0.2619	No
126	SMS	ENSG00000102172.16			38982	-1.305	-0.2567	No
127	MDH2	ENSG00000146701.12			39149	-1.341	-0.2532	No
128	ACADM	ENSG00000117054.13			39201	-1.353	-0.2470	No
129	DECR1	ENSG00000104325.7			39242	-1.363	-0.2405	No
130	ME1	ENSG00000065833.9			39319	-1.382	-0.2347	No
131	HCCS	ENSG00000004961.15			39422	-1.404	-0.2294	No
132	SUCLA2	ENSG00000136143.16			39428	-1.405	-0.2218	No
133	ECHS1	ENSG00000127884.5			39473	-1.417	-0.2151	No
134	DLD	ENSG00000091140.14			39495	-1.421	-0.2078	No
135	HSPH1	ENSG00000120694.20			39642	-1.452	-0.2032	No
136	ACADL	ENSG00000115361.8			39688	-1.463	-0.1963	No
137	ENO2	ENSG00000111674.9			39689	-1.464	-0.1883	No
138	ACSL1	ENSG00000151726.14			40389	-1.654	-0.1955	No
139	HADH	ENSG00000138796.16			40435	-1.667	-0.1874	No
140	PDHB	ENSG00000168291.13			40487	-1.684	-0.1794	No
141	RAP1GDS1	ENSG00000138698.14			40532	-1.697	-0.1711	No
142	CD1D	ENSG00000158473.6			40635	-1.730	-0.1640	No
143	SLC22A5	ENSG00000197375.12			40836	-1.797	-0.1589	No
144	ACAA2	ENSG00000167315.18			41011	-1.873	-0.1527	No
145	PDHA1	ENSG00000131828.14			41112	-1.913	-0.1445	No
146	PRDX6	ENSG00000117592.9			41173	-1.946	-0.1353	No
147	AOC3	ENSG00000131471.7			41327	-2.021	-0.1278	No
148	HSD17B10	ENSG00000072506.12			41554	-2.165	-0.1212	No
149	GPD1	ENSG00000167588.13			41796	-2.325	-0.1141	No
150	FABP1	ENSG00000163586.10			41951	-2.456	-0.1042	No
151	G0S2	ENSG00000123689.6			41996	-2.485	-0.0917	No
152	ACSL4	ENSG00000068366.20			42004	-2.493	-0.0782	No
153	ADSL	ENSG00000239900.12			42041	-2.520	-0.0652	No
154	ODC1	ENSG00000115758.13			42710	-3.622	-0.0610	No
155	TP53INP2	ENSG00000078804.13			42758	-3.743	-0.0416	No
156	ENO3	ENSG00000108515.17			42958	-4.537	-0.0214	No
157	ALDH1A1	ENSG00000165092.13			42972	-4.592	0.0034	No

Fig 2: HALLMARK_FATTY_ACID_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_FATTY_ACID_METABOLISM: Random ES distribution   
Gene set null distribution of ES for HALLMARK_FATTY_ACID_METABOLISM