Details for gene set HALLMARK_GLYCOLYSIS[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2M
GeneSet	HALLMARK_GLYCOLYSIS
Enrichment Score (ES)	-0.3482364
Normalized Enrichment Score (NES)	-1.3862257
Nominal p-value	0.012211669
FDR q-value	0.045923103
FWER p-Value	0.6

Fig 1: Enrichment plot: HALLMARK_GLYCOLYSIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DCN	ENSG00000011465.17			6	4.734	0.0207	No
2	STC1	ENSG00000159167.12			146	3.499	0.0329	No
3	CD44	ENSG00000026508.18			157	3.446	0.0478	No
4	ANG	ENSG00000214274.9			174	3.361	0.0622	No
5	PAM	ENSG00000145730.20			235	3.193	0.0749	No
6	TPBG	ENSG00000146242.8			331	2.893	0.0854	No
7	GNPDA1	ENSG00000113552.16			482	2.630	0.0935	No
8	EGFR	ENSG00000146648.18			529	2.570	0.1038	No
9	KDELR3	ENSG00000100196.11			547	2.546	0.1146	No
10	IDH1	ENSG00000138413.13			771	2.290	0.1195	No
11	FUT8	ENSG00000033170.16			944	2.136	0.1249	No
12	CAPN5	ENSG00000149260.18			1156	2.013	0.1288	No
13	SDC3	ENSG00000162512.16			1208	1.985	0.1363	No
14	IDUA	ENSG00000127415.13			1270	1.956	0.1435	No
15	GCLC	ENSG00000001084.13			1297	1.942	0.1515	No
16	GALK1	ENSG00000108479.12			1302	1.936	0.1599	No
17	CHST2	ENSG00000175040.6			1311	1.932	0.1682	No
18	EXT1	ENSG00000182197.11			1424	1.876	0.1739	No
19	LHX9	ENSG00000143355.16			1636	1.787	0.1768	No
20	G6PD	ENSG00000160211.19			1825	1.702	0.1800	No
21	IGFBP3	ENSG00000146674.15			1828	1.702	0.1874	No
22	NT5E	ENSG00000135318.12			2035	1.617	0.1897	No
23	CYB5A	ENSG00000166347.19			2498	1.475	0.1855	No
24	CHST12	ENSG00000136213.10			2676	1.416	0.1876	No
25	ERO1A	ENSG00000197930.13			2702	1.409	0.1932	No
26	TPST1	ENSG00000169902.15			2718	1.403	0.1990	No
27	MXI1	ENSG00000119950.21			2783	1.382	0.2036	No
28	EFNA3	ENSG00000143590.14			2946	1.345	0.2057	No
29	ISG20	ENSG00000172183.15			3169	1.296	0.2063	No
30	TXN	ENSG00000136810.13			3238	1.278	0.2103	No
31	IL13RA1	ENSG00000131724.11			3381	1.248	0.2125	No
32	GUSB	ENSG00000169919.17			3543	1.217	0.2141	No
33	EXT2	ENSG00000151348.14			4096	1.112	0.2062	No
34	GAPDHS	ENSG00000105679.9			4145	1.104	0.2099	No
35	GNE	ENSG00000159921.16			4446	1.053	0.2076	No
36	IRS2	ENSG00000185950.9			5127	0.950	0.1959	No
37	RPE	ENSG00000197713.15			5582	0.890	0.1892	No
38	B4GALT2	ENSG00000117411.16			5636	0.883	0.1919	No
39	GLCE	ENSG00000138604.10			5870	0.856	0.1902	No
40	SRD5A3	ENSG00000128039.11			6114	0.828	0.1882	No
41	RBCK1	ENSG00000125826.20			6153	0.822	0.1909	No
42	GPC3	ENSG00000147257.14			6374	0.800	0.1893	No
43	CITED2	ENSG00000164442.10			6826	0.755	0.1822	No
44	NANP	ENSG00000170191.5			6887	0.749	0.1841	No
45	GALK2	ENSG00000156958.15			6911	0.745	0.1868	No
46	ARTN	ENSG00000117407.17			7254	0.713	0.1820	No
47	ANGPTL4	ENSG00000167772.12			7297	0.710	0.1841	No
48	NDST3	ENSG00000164100.9			7545	0.686	0.1814	No
49	NSDHL	ENSG00000147383.11			7604	0.679	0.1830	No
50	XYLT2	ENSG00000015532.10			8143	0.634	0.1733	No
51	QSOX1	ENSG00000116260.17			8176	0.631	0.1753	No
52	AKR1A1	ENSG00000117448.13			8923	0.574	0.1605	No
53	AK3	ENSG00000147853.17			9505	0.537	0.1493	No
54	HS2ST1	ENSG00000153936.17			9818	0.521	0.1443	No
55	B4GALT4	ENSG00000121578.13			10003	0.511	0.1423	No
56	CHST1	ENSG00000175264.8			10240	0.494	0.1390	No
57	ALG1	ENSG00000033011.12			10420	0.483	0.1369	No
58	MERTK	ENSG00000153208.17			11025	0.443	0.1248	No
59	ALDH9A1	ENSG00000143149.12			11047	0.441	0.1263	No
60	PMM2	ENSG00000140650.12			11739	0.401	0.1119	No
61	ZNF292	ENSG00000188994.13			11965	0.389	0.1084	No
62	HDLBP	ENSG00000115677.17			12315	0.374	0.1019	No
63	GMPPA	ENSG00000144591.18			12412	0.368	0.1013	No
64	SDC1	ENSG00000115884.11			13286	0.340	0.0824	No
65	PPIA	ENSG00000196262.14			13437	0.331	0.0804	No
66	B3GAT1	ENSG00000109956.13			13926	0.321	0.0705	No
67	PYGB	ENSG00000100994.12			14574	0.306	0.0567	No
68	CHPF2	ENSG00000033100.16			14681	0.298	0.0556	No
69	GPR87	ENSG00000138271.6			14912	0.287	0.0515	No
70	B3GNT3	ENSG00000179913.11			15102	0.287	0.0483	No
71	PLOD1	ENSG00000083444.17			15475	0.276	0.0409	No
72	B4GALT7	ENSG00000027847.14			15732	0.264	0.0361	No
73	PDK3	ENSG00000067992.15			16173	0.238	0.0269	No
74	AC010618.1	ENSG00000243771.1			16257	0.232	0.0260	No
75	SPAG4	ENSG00000061656.10			16720	0.209	0.0161	No
76	SLC35A3	ENSG00000117620.15			16763	0.207	0.0161	No
77	ADORA2B	ENSG00000170425.3			17637	0.167	-0.0035	No
78	PHKA2	ENSG00000044446.12			17734	0.161	-0.0051	No
79	ALDOB	ENSG00000136872.20			18294	0.131	-0.0175	No
80	ALDH7A1	ENSG00000164904.18			18498	0.125	-0.0217	No
81	PAXIP1	ENSG00000157212.19			18715	0.112	-0.0262	No
82	TSTA3	ENSG00000104522.16			18779	0.108	-0.0272	No
83	GYS2	ENSG00000111713.3			19284	0.084	-0.0386	No
84	COPB2	ENSG00000184432.10			19469	0.072	-0.0426	No
85	LHPP	ENSG00000107902.14			19528	0.070	-0.0436	No
86	SLC37A4	ENSG00000137700.18			20042	0.046	-0.0554	No
87	SOD1	ENSG00000142168.14			20939	-0.001	-0.0762	No
88	HK2	ENSG00000159399.9			21120	-0.012	-0.0804	No
89	LDHC	ENSG00000166796.12			21646	-0.039	-0.0924	No
90	ANKZF1	ENSG00000163516.14			21692	-0.042	-0.0933	No
91	LDHA	ENSG00000134333.14			23158	-0.122	-0.1269	No
92	MIOX	ENSG00000100253.13			23442	-0.138	-0.1329	No
93	FAM162A	ENSG00000114023.15			23550	-0.144	-0.1347	No
94	BIK	ENSG00000100290.3			24053	-0.174	-0.1457	No
95	STC2	ENSG00000113739.10			24147	-0.179	-0.1470	No
96	PFKP	ENSG00000067057.17			25775	-0.245	-0.1839	No
97	SOX9	ENSG00000125398.8			25922	-0.255	-0.1862	No
98	AGRN	ENSG00000188157.15			25926	-0.255	-0.1851	No
99	AC074143.1	ENSG00000265690.7			26002	-0.260	-0.1857	No
100	HAX1	ENSG00000143575.14			26609	-0.274	-0.1986	No
101	B3GALT6	ENSG00000176022.7			27204	-0.288	-0.2112	No
102	GFPT1	ENSG00000198380.12			27981	-0.307	-0.2279	No
103	PYGL	ENSG00000100504.17			28280	-0.328	-0.2334	No
104	DPYSL4	ENSG00000151640.13			28281	-0.328	-0.2320	No
105	GMPPB	ENSG00000173540.12			28708	-0.345	-0.2404	No
106	SAP30	ENSG00000164105.4			28782	-0.351	-0.2405	No
107	TALDO1	ENSG00000177156.11			29360	-0.367	-0.2523	No
108	AURKA	ENSG00000087586.17			29575	-0.379	-0.2557	No
109	CLDN3	ENSG00000165215.6			29677	-0.385	-0.2563	No
110	KIF20A	ENSG00000112984.12			29750	-0.391	-0.2563	No
111	CENPA	ENSG00000115163.15			30030	-0.409	-0.2610	No
112	MIF	ENSG00000240972.2			30243	-0.424	-0.2640	No
113	SDHC	ENSG00000143252.14			30372	-0.429	-0.2651	No
114	GPC4	ENSG00000076716.9			30378	-0.430	-0.2634	No
115	CASP6	ENSG00000138794.10			30445	-0.435	-0.2630	No
116	P4HA1	ENSG00000122884.12			30621	-0.444	-0.2651	No
117	TGFA	ENSG00000163235.16			31003	-0.459	-0.2720	No
118	CTH	ENSG00000116761.12			31007	-0.460	-0.2700	No
119	CDK1	ENSG00000170312.16			31062	-0.464	-0.2692	No
120	TKTL1	ENSG00000007350.17			31396	-0.485	-0.2748	No
121	LCT	ENSG00000115850.10			31588	-0.495	-0.2771	No
122	CLN6	ENSG00000128973.13			31748	-0.500	-0.2786	No
123	UGP2	ENSG00000169764.15			32243	-0.531	-0.2878	No
124	SDC2	ENSG00000169439.12			32389	-0.538	-0.2888	No
125	DSC2	ENSG00000134755.17			32605	-0.552	-0.2914	No
126	POLR3K	ENSG00000161980.6			32861	-0.573	-0.2948	No
127	HMMR	ENSG00000072571.20			33009	-0.584	-0.2957	No
128	PGAM1	ENSG00000171314.9			33088	-0.589	-0.2949	No
129	IER3	ENSG00000137331.12			33260	-0.602	-0.2962	No
130	PGM2	ENSG00000169299.14			33294	-0.604	-0.2943	No
131	MDH1	ENSG00000014641.19			34029	-0.662	-0.3085	No
132	CXCR4	ENSG00000121966.6			34272	-0.681	-0.3111	No
133	ARPP19	ENSG00000128989.10			34335	-0.686	-0.3096	No
134	PPP2CB	ENSG00000104695.13			34925	-0.735	-0.3201	No
135	CHST6	ENSG00000183196.10			34994	-0.741	-0.3184	No
136	AK4	ENSG00000162433.15			35031	-0.743	-0.3159	No
137	DEPDC1	ENSG00000024526.17			35083	-0.749	-0.3138	No
138	ABCB6	ENSG00000115657.14			35179	-0.758	-0.3127	No
139	ENO1	ENSG00000074800.16			35286	-0.766	-0.3118	No
140	ELF3	ENSG00000163435.16			35419	-0.779	-0.3114	No
141	CHPF	ENSG00000123989.14			35695	-0.808	-0.3143	No
142	RARS	ENSG00000113643.9			35724	-0.811	-0.3114	No
143	VCAN	ENSG00000038427.16			36187	-0.866	-0.3183	No
144	ME2	ENSG00000082212.13			36575	-0.910	-0.3233	No
145	COL5A1	ENSG00000130635.15			37069	-0.977	-0.3305	No
146	NDUFV3	ENSG00000160194.18			37212	-0.994	-0.3295	No
147	CLDN9	ENSG00000213937.4			37970	-1.113	-0.3422	No
148	CHST4	ENSG00000140835.9			38216	-1.156	-0.3428	No
149	GOT2	ENSG00000125166.13			38450	-1.197	-0.3430	Yes
150	SLC25A10	ENSG00000183048.12			38567	-1.217	-0.3403	Yes
151	ALDOA	ENSG00000149925.20			38602	-1.223	-0.3357	Yes
152	DDIT4	ENSG00000168209.5			38633	-1.230	-0.3310	Yes
153	HS6ST2	ENSG00000171004.18			38651	-1.234	-0.3260	Yes
154	ECD	ENSG00000122882.11			38836	-1.275	-0.3246	Yes
155	MET	ENSG00000105976.15			39028	-1.316	-0.3233	Yes
156	TFF3	ENSG00000160180.15			39084	-1.327	-0.3187	Yes
157	MDH2	ENSG00000146701.12			39149	-1.341	-0.3143	Yes
158	PFKFB1	ENSG00000158571.11			39237	-1.362	-0.3103	Yes
159	ME1	ENSG00000065833.9			39319	-1.382	-0.3061	Yes
160	B3GAT3	ENSG00000149541.10			39360	-1.390	-0.3010	Yes
161	DLD	ENSG00000091140.14			39495	-1.421	-0.2978	Yes
162	GOT1	ENSG00000120053.12			39598	-1.441	-0.2939	Yes
163	TPI1	ENSG00000111669.15			39620	-1.447	-0.2880	Yes
164	ENO2	ENSG00000111674.9			39689	-1.464	-0.2831	Yes
165	GAL3ST1	ENSG00000128242.13			39722	-1.472	-0.2774	Yes
166	B4GALT1	ENSG00000086062.12			39786	-1.489	-0.2723	Yes
167	NASP	ENSG00000132780.17			39879	-1.517	-0.2678	Yes
168	BPNT1	ENSG00000162813.18			40325	-1.634	-0.2709	Yes
169	SLC16A3	ENSG00000141526.16			40378	-1.650	-0.2649	Yes
170	PSMC4	ENSG00000013275.8			40405	-1.659	-0.2582	Yes
171	CACNA1H	ENSG00000196557.13			40414	-1.660	-0.2511	Yes
172	KIF2A	ENSG00000068796.16			40453	-1.672	-0.2446	Yes
173	MED24	ENSG00000008838.20			40471	-1.679	-0.2376	Yes
174	TGFBI	ENSG00000120708.17			40715	-1.752	-0.2355	Yes
175	VEGFA	ENSG00000112715.22			40824	-1.792	-0.2302	Yes
176	FKBP4	ENSG00000004478.8			41079	-1.899	-0.2277	Yes
177	GLRX	ENSG00000173221.14			41105	-1.909	-0.2199	Yes
178	PGK1	ENSG00000102144.15			41108	-1.912	-0.2115	Yes
179	VLDLR	ENSG00000147852.16			41219	-1.967	-0.2054	Yes
180	AGL	ENSG00000162688.17			41336	-2.026	-0.1992	Yes
181	PKP2	ENSG00000057294.14			41353	-2.035	-0.1906	Yes
182	SLC25A13	ENSG00000004864.13			41429	-2.086	-0.1832	Yes
183	P4HA2	ENSG00000072682.18			41436	-2.093	-0.1741	Yes
184	PC	ENSG00000173599.15			41477	-2.119	-0.1657	Yes
185	RRAGD	ENSG00000025039.15			41478	-2.121	-0.1564	Yes
186	GALE	ENSG00000117308.15			41501	-2.130	-0.1475	Yes
187	COG2	ENSG00000135775.14			41596	-2.191	-0.1400	Yes
188	HSPA5	ENSG00000044574.8			41668	-2.232	-0.1319	Yes
189	STMN1	ENSG00000117632.23			41736	-2.282	-0.1234	Yes
190	PKM	ENSG00000067225.18			41955	-2.458	-0.1176	Yes
191	PRPS1	ENSG00000147224.11			42335	-2.892	-0.1137	Yes
192	MPI	ENSG00000178802.18			42513	-3.147	-0.1040	Yes
193	PLOD2	ENSG00000152952.12			42521	-3.156	-0.0903	Yes
194	GPC1	ENSG00000063660.9			42528	-3.165	-0.0765	Yes
195	HOMER1	ENSG00000152413.15			42639	-3.438	-0.0639	Yes
196	FBP2	ENSG00000130957.5			42669	-3.502	-0.0492	Yes
197	GYS1	ENSG00000104812.15			42908	-4.311	-0.0357	Yes
198	PPFIA4	ENSG00000143847.15			42964	-4.552	-0.0170	Yes
199	EGLN3	ENSG00000129521.14			42986	-4.666	0.0031	Yes

Fig 2: HALLMARK_GLYCOLYSIS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_GLYCOLYSIS: Random ES distribution   
Gene set null distribution of ES for HALLMARK_GLYCOLYSIS