Details for gene set HALLMARK

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2M
GeneSet	HALLMARK_HYPOXIA
Enrichment Score (ES)	-0.33201227
Normalized Enrichment Score (NES)	-1.3433425
Nominal p-value	0.022941971
FDR q-value	0.0659011
FWER p-Value	0.745

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DCN	ENSG00000011465.17	6	4.734	0.0185	No
2	ADM	ENSG00000148926.10	19	4.384	0.0354	No
3	STC1	ENSG00000159167.12	146	3.499	0.0462	No
4	PAM	ENSG00000145730.20	235	3.193	0.0567	No
5	TPBG	ENSG00000146242.8	331	2.893	0.0659	No
6	ZFP36	ENSG00000128016.7	348	2.862	0.0768	No
7	BCL2	ENSG00000171791.13	349	2.862	0.0880	No
8	SLC25A1	ENSG00000100075.10	364	2.822	0.0988	No
9	PLIN2	ENSG00000147872.10	455	2.674	0.1072	No
10	EGFR	ENSG00000146648.18	529	2.570	0.1156	No
11	KDELR3	ENSG00000100196.11	547	2.546	0.1252	No
12	AKAP12	ENSG00000131016.17	561	2.526	0.1348	No
13	GCK	ENSG00000106633.17	573	2.506	0.1444	No
14	SRPX	ENSG00000101955.15	660	2.402	0.1519	No
15	RORA	ENSG00000069667.16	686	2.376	0.1606	No
16	NR3C1	ENSG00000113580.15	693	2.369	0.1698	No
17	SDC4	ENSG00000124145.6	886	2.182	0.1739	No
18	MAFF	ENSG00000185022.12	1086	2.057	0.1773	No
19	SDC3	ENSG00000162512.16	1208	1.985	0.1823	No
20	GALK1	ENSG00000108479.12	1302	1.936	0.1878	No
21	CHST2	ENSG00000175040.6	1311	1.932	0.1952	No
22	EXT1	ENSG00000182197.11	1424	1.876	0.1999	No
23	LOX	ENSG00000113083.14	1511	1.838	0.2051	No
24	S100A4	ENSG00000196154.12	1525	1.834	0.2121	No
25	SELENBP1	ENSG00000143416.21	1592	1.804	0.2176	No
26	CP	ENSG00000047457.14	1593	1.802	0.2247	No
27	PNRC1	ENSG00000146278.11	1595	1.801	0.2317	No
28	GAA	ENSG00000171298.13	1658	1.772	0.2373	No
29	IGFBP3	ENSG00000146674.15	1828	1.702	0.2400	No
30	ALDOC	ENSG00000109107.14	2040	1.615	0.2414	No
31	NDRG1	ENSG00000104419.14	2162	1.579	0.2448	No
32	CCN5	ENSG00000064205.10	2260	1.545	0.2486	No
33	HEXA	ENSG00000213614.9	2587	1.446	0.2467	No
34	KIF5A	ENSG00000155980.12	2645	1.427	0.2510	No
35	CAV1	ENSG00000105974.12	2696	1.410	0.2554	No
36	ERO1A	ENSG00000197930.13	2702	1.409	0.2608	No
37	MXI1	ENSG00000119950.21	2783	1.382	0.2644	No
38	NFIL3	ENSG00000165030.4	2885	1.360	0.2674	No
39	EFNA3	ENSG00000143590.14	2946	1.345	0.2713	No
40	CA12	ENSG00000074410.14	3104	1.310	0.2727	No
41	ISG20	ENSG00000172183.15	3169	1.296	0.2763	No
42	KLF6	ENSG00000067082.15	3324	1.262	0.2777	No
43	BNIP3L	ENSG00000104765.16	3379	1.249	0.2814	No
44	SCARB1	ENSG00000073060.16	3609	1.204	0.2808	No
45	PPARGC1A	ENSG00000109819.9	3945	1.138	0.2774	No
46	GAPDHS	ENSG00000105679.9	4145	1.104	0.2771	No
47	DDIT3	ENSG00000175197.12	4354	1.068	0.2765	No
48	NDST2	ENSG00000166507.18	4652	1.022	0.2736	No
49	GBE1	ENSG00000114480.13	4933	0.978	0.2709	No
50	IRS2	ENSG00000185950.9	5127	0.950	0.2701	No
51	CAVIN3	ENSG00000170955.10	5455	0.905	0.2661	No
52	CDKN1B	ENSG00000111276.11	6128	0.825	0.2537	No
53	GPC3	ENSG00000147257.14	6374	0.800	0.2511	No
54	CITED2	ENSG00000164442.10	6826	0.755	0.2436	No
55	ACKR3	ENSG00000144476.6	6973	0.741	0.2431	No
56	PRDX5	ENSG00000126432.14	7130	0.725	0.2423	No
57	BGN	ENSG00000182492.16	7136	0.724	0.2450	No
58	ANGPTL4	ENSG00000167772.12	7297	0.710	0.2441	No
59	MAP3K1	ENSG00000095015.6	7811	0.662	0.2347	No
60	TMEM45A	ENSG00000181458.10	8152	0.633	0.2293	No
61	PRKCA	ENSG00000154229.12	8575	0.601	0.2218	No
62	SLC6A6	ENSG00000131389.17	8830	0.581	0.2182	No
63	SULT2B1	ENSG00000088002.11	8911	0.575	0.2186	No
64	PLAC8	ENSG00000145287.10	8949	0.571	0.2200	No
65	HMOX1	ENSG00000100292.17	9579	0.532	0.2074	No
66	IDS	ENSG00000010404.18	9593	0.530	0.2092	No
67	FOS	ENSG00000170345.10	9664	0.525	0.2096	No
68	ANXA2	ENSG00000182718.16	9909	0.516	0.2060	No
69	RBPJ	ENSG00000168214.20	10236	0.495	0.2003	No
70	PFKFB3	ENSG00000170525.21	10834	0.456	0.1882	No
71	F3	ENSG00000117525.14	11227	0.431	0.1808	No
72	PHKG1	ENSG00000164776.9	11605	0.408	0.1736	No
73	KLHL24	ENSG00000114796.16	11659	0.404	0.1739	No
74	ZNF292	ENSG00000188994.13	11965	0.389	0.1684	No
75	HDLBP	ENSG00000115677.17	12315	0.374	0.1617	No
76	BTG1	ENSG00000133639.5	14119	0.310	0.1209	No
77	TGM2	ENSG00000198959.12	14132	0.309	0.1218	No
78	LALBA	ENSG00000167531.6	14403	0.308	0.1168	No
79	PPP1R15A	ENSG00000087074.8	14858	0.289	0.1073	No
80	EDN2	ENSG00000127129.10	15879	0.255	0.0846	No
81	PDK3	ENSG00000067992.15	16173	0.238	0.0787	No
82	CCNG2	ENSG00000138764.15	16472	0.221	0.0726	No
83	PIM1	ENSG00000137193.14	16645	0.213	0.0694	No
84	PKLR	ENSG00000143627.19	16884	0.203	0.0647	No
85	ADORA2B	ENSG00000170425.3	17637	0.167	0.0478	No
86	SLC2A3	ENSG00000059804.16	17679	0.164	0.0475	No
87	CAVIN1	ENSG00000177469.13	17895	0.152	0.0431	No
88	ALDOB	ENSG00000136872.20	18294	0.131	0.0343	No
89	PPP1R3C	ENSG00000119938.9	18717	0.111	0.0249	No
90	FOXO3	ENSG00000118689.15	18792	0.107	0.0236	No
91	SLC37A4	ENSG00000137700.18	20042	0.046	-0.0053	No
92	HS3ST1	ENSG00000002587.10	20959	-0.002	-0.0266	No
93	HK2	ENSG00000159399.9	21120	-0.012	-0.0303	No
94	MT1E	ENSG00000169715.15	21218	-0.017	-0.0325	No
95	LDHC	ENSG00000166796.12	21646	-0.039	-0.0423	No
96	ANKZF1	ENSG00000163516.14	21692	-0.042	-0.0432	No
97	BRS3	ENSG00000102239.5	21956	-0.054	-0.0491	No
98	LXN	ENSG00000079257.8	22002	-0.057	-0.0499	No
99	CCN1	ENSG00000142871.17	22390	-0.079	-0.0586	No
100	NDST1	ENSG00000070614.15	22746	-0.098	-0.0665	No
101	SIAH2	ENSG00000181788.4	23013	-0.113	-0.0723	No
102	LDHA	ENSG00000134333.14	23158	-0.122	-0.0751	No
103	ILVBL	ENSG00000105135.16	23187	-0.123	-0.0753	No
104	VHL	ENSG00000134086.7	23321	-0.131	-0.0779	No
105	FAM162A	ENSG00000114023.15	23550	-0.144	-0.0826	No
106	NAGK	ENSG00000124357.13	23956	-0.169	-0.0914	No
107	STC2	ENSG00000113739.10	24147	-0.179	-0.0951	No
108	TIPARP	ENSG00000163659.13	24403	-0.193	-0.1003	No
109	STBD1	ENSG00000118804.8	25451	-0.223	-0.1238	No
110	PFKP	ENSG00000067057.17	25775	-0.245	-0.1304	No
111	ATF3	ENSG00000162772.17	25795	-0.246	-0.1299	No
112	B3GALT6	ENSG00000176022.7	27204	-0.288	-0.1615	No
113	TPST2	ENSG00000128294.16	28000	-0.309	-0.1788	No
114	DPYSL4	ENSG00000151640.13	28281	-0.328	-0.1841	No
115	SAP30	ENSG00000164105.4	28782	-0.351	-0.1944	No
116	PCK1	ENSG00000124253.11	28897	-0.351	-0.1956	No
117	MT2A	ENSG00000125148.7	29124	-0.355	-0.1995	No
118	B4GALNT2	ENSG00000167080.8	30188	-0.420	-0.2226	No
119	MIF	ENSG00000240972.2	30243	-0.424	-0.2222	No
120	GPC4	ENSG00000076716.9	30378	-0.430	-0.2236	No
121	CASP6	ENSG00000138794.10	30445	-0.435	-0.2235	No
122	INHA	ENSG00000123999.5	30454	-0.436	-0.2219	No
123	P4HA1	ENSG00000122884.12	30621	-0.444	-0.2241	No
124	NCAN	ENSG00000130287.14	31294	-0.478	-0.2378	No
125	TKTL1	ENSG00000007350.17	31396	-0.485	-0.2383	No
126	PGM1	ENSG00000079739.17	31611	-0.495	-0.2413	No
127	UGP2	ENSG00000169764.15	32243	-0.531	-0.2539	No
128	SDC2	ENSG00000169439.12	32389	-0.538	-0.2552	No
129	PDK1	ENSG00000152256.13	32654	-0.556	-0.2592	No
130	CCN2	ENSG00000118523.6	32823	-0.570	-0.2608	No
131	CSRP2	ENSG00000175183.10	33085	-0.589	-0.2646	No
132	ETS1	ENSG00000134954.14	33090	-0.589	-0.2624	No
133	IER3	ENSG00000137331.12	33260	-0.602	-0.2640	No
134	PGM2	ENSG00000169299.14	33294	-0.604	-0.2624	No
135	HK1	ENSG00000156515.23	34153	-0.673	-0.2797	No
136	CXCR4	ENSG00000121966.6	34272	-0.681	-0.2798	No
137	GPI	ENSG00000105220.17	34273	-0.681	-0.2771	No
138	AK4	ENSG00000162433.15	35031	-0.743	-0.2918	No
139	ENO1	ENSG00000074800.16	35286	-0.766	-0.2947	No
140	TGFB3	ENSG00000119699.7	35467	-0.784	-0.2958	No
141	PFKL	ENSG00000141959.17	36723	-0.933	-0.3214	No
142	COL5A1	ENSG00000130635.15	37069	-0.977	-0.3256	No
143	JUN	ENSG00000177606.7	37141	-0.985	-0.3234	No
144	WSB1	ENSG00000109046.15	37224	-0.995	-0.3214	No
145	IL6	ENSG00000136244.12	37366	-1.015	-0.3207	No
146	CDKN1A	ENSG00000124762.13	37465	-1.029	-0.3189	No
147	GRHPR	ENSG00000137106.18	37896	-1.100	-0.3246	No
148	AMPD3	ENSG00000133805.15	37969	-1.113	-0.3219	No
149	SERPINE1	ENSG00000106366.8	38403	-1.189	-0.3273	Yes
150	ALDOA	ENSG00000149925.20	38602	-1.223	-0.3271	Yes
151	DDIT4	ENSG00000168209.5	38633	-1.230	-0.3230	Yes
152	ATP7A	ENSG00000165240.20	38659	-1.235	-0.3187	Yes
153	KDM3A	ENSG00000115548.17	38941	-1.297	-0.3202	Yes
154	FBP1	ENSG00000165140.10	39215	-1.356	-0.3212	Yes
155	XPNPEP1	ENSG00000108039.18	39332	-1.384	-0.3185	Yes
156	GAPDH	ENSG00000111640.15	39341	-1.385	-0.3132	Yes
157	TNFAIP3	ENSG00000118503.15	39359	-1.390	-0.3082	Yes
158	KLF7	ENSG00000118263.15	39515	-1.424	-0.3062	Yes
159	TPI1	ENSG00000111669.15	39620	-1.447	-0.3029	Yes
160	ENO2	ENSG00000111674.9	39689	-1.464	-0.2987	Yes
161	JMJD6	ENSG00000070495.14	40038	-1.558	-0.3007	Yes
162	DUSP1	ENSG00000120129.6	40039	-1.558	-0.2946	Yes
163	FOSL2	ENSG00000075426.12	40066	-1.563	-0.2891	Yes
164	NOCT	ENSG00000151014.6	40107	-1.575	-0.2838	Yes
165	BHLHE40	ENSG00000134107.5	40173	-1.593	-0.2791	Yes
166	IGFBP1	ENSG00000146678.10	40197	-1.599	-0.2733	Yes
167	TPD52	ENSG00000076554.15	40238	-1.609	-0.2679	Yes
168	SLC2A5	ENSG00000142583.18	40648	-1.734	-0.2706	Yes
169	TGFBI	ENSG00000120708.17	40715	-1.752	-0.2653	Yes
170	VEGFA	ENSG00000112715.22	40824	-1.792	-0.2608	Yes
171	TES	ENSG00000135269.18	40832	-1.795	-0.2539	Yes
172	DTNA	ENSG00000134769.21	40940	-1.838	-0.2492	Yes
173	LARGE1	ENSG00000133424.20	40958	-1.846	-0.2423	Yes
174	GLRX	ENSG00000173221.14	41105	-1.909	-0.2382	Yes
175	PGK1	ENSG00000102144.15	41108	-1.912	-0.2307	Yes
176	CDKN1C	ENSG00000129757.13	41169	-1.945	-0.2245	Yes
177	PLAUR	ENSG00000011422.12	41170	-1.945	-0.2168	Yes
178	VLDLR	ENSG00000147852.16	41219	-1.967	-0.2102	Yes
179	GCNT2	ENSG00000111846.17	41340	-2.028	-0.2051	Yes
180	HOXB9	ENSG00000170689.10	41370	-2.045	-0.1977	Yes
181	P4HA2	ENSG00000072682.18	41436	-2.093	-0.1910	Yes
182	RRAGD	ENSG00000025039.15	41478	-2.121	-0.1836	Yes
183	MYH9	ENSG00000100345.21	41599	-2.193	-0.1778	Yes
184	HSPA5	ENSG00000044574.8	41668	-2.232	-0.1706	Yes
185	SLC2A1	ENSG00000117394.23	41840	-2.358	-0.1653	Yes
186	PDGFB	ENSG00000100311.17	41932	-2.434	-0.1579	Yes
187	PKP1	ENSG00000081277.12	42078	-2.554	-0.1512	Yes
188	HAS1	ENSG00000105509.10	42114	-2.593	-0.1418	Yes
189	PGF	ENSG00000119630.14	42142	-2.627	-0.1321	Yes
190	ERRFI1	ENSG00000116285.13	42466	-3.084	-0.1275	Yes
191	NEDD4L	ENSG00000049759.18	42475	-3.096	-0.1156	Yes
192	GPC1	ENSG00000063660.9	42528	-3.165	-0.1043	Yes
193	CHST3	ENSG00000122863.6	42705	-3.609	-0.0942	Yes
194	EFNA1	ENSG00000169242.12	42868	-4.183	-0.0816	Yes
195	PYGM	ENSG00000068976.14	42896	-4.270	-0.0654	Yes
196	GYS1	ENSG00000104812.15	42908	-4.311	-0.0487	Yes
197	ENO3	ENSG00000108515.17	42958	-4.537	-0.0320	Yes
198	BCAN	ENSG00000132692.19	42962	-4.544	-0.0143	Yes
199	PPFIA4	ENSG00000143847.15	42964	-4.552	0.0036	Yes