Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | 0.5029382 |
| Normalized Enrichment Score (NES) | 2.0007427 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ACVRL1 | ENSG00000139567.12 | 133 | 3.547 | 0.0371 | Yes | ||
| 2 | CD44 | ENSG00000026508.18 | 157 | 3.446 | 0.0756 | Yes | ||
| 3 | IL7 | ENSG00000104432.14 | 187 | 3.332 | 0.1127 | Yes | ||
| 4 | IL6ST | ENSG00000134352.20 | 282 | 3.044 | 0.1450 | Yes | ||
| 5 | IL1R1 | ENSG00000115594.12 | 542 | 2.559 | 0.1679 | Yes | ||
| 6 | IFNGR2 | ENSG00000159128.14 | 882 | 2.184 | 0.1848 | Yes | ||
| 7 | FAS | ENSG00000026103.22 | 911 | 2.164 | 0.2087 | Yes | ||
| 8 | STAT2 | ENSG00000170581.14 | 1323 | 1.925 | 0.2209 | Yes | ||
| 9 | IL17RA | ENSG00000177663.13 | 1338 | 1.916 | 0.2423 | Yes | ||
| 10 | STAT1 | ENSG00000115415.18 | 1379 | 1.893 | 0.2628 | Yes | ||
| 11 | IFNAR1 | ENSG00000142166.13 | 1384 | 1.890 | 0.2841 | Yes | ||
| 12 | IL15RA | ENSG00000134470.21 | 1434 | 1.873 | 0.3042 | Yes | ||
| 13 | CD9 | ENSG00000010278.14 | 1562 | 1.814 | 0.3218 | Yes | ||
| 14 | CD14 | ENSG00000170458.14 | 1584 | 1.809 | 0.3418 | Yes | ||
| 15 | TNFRSF1B | ENSG00000028137.19 | 1790 | 1.722 | 0.3566 | Yes | ||
| 16 | IL10RB | ENSG00000243646.10 | 2126 | 1.591 | 0.3668 | Yes | ||
| 17 | CD36 | ENSG00000135218.19 | 2200 | 1.566 | 0.3828 | Yes | ||
| 18 | CSF1 | ENSG00000184371.14 | 2219 | 1.559 | 0.4001 | Yes | ||
| 19 | MYD88 | ENSG00000172936.14 | 2301 | 1.535 | 0.4156 | Yes | ||
| 20 | IL17RB | ENSG00000056736.10 | 2614 | 1.438 | 0.4246 | Yes | ||
| 21 | IL1R2 | ENSG00000115590.14 | 2747 | 1.394 | 0.4374 | Yes | ||
| 22 | CCL7 | ENSG00000108688.11 | 3096 | 1.310 | 0.4441 | Yes | ||
| 23 | IRF9 | ENSG00000213928.9 | 3253 | 1.277 | 0.4549 | Yes | ||
| 24 | IL13RA1 | ENSG00000131724.11 | 3381 | 1.248 | 0.4661 | Yes | ||
| 25 | TNFRSF1A | ENSG00000067182.7 | 3407 | 1.243 | 0.4796 | Yes | ||
| 26 | IRF1 | ENSG00000125347.14 | 3458 | 1.235 | 0.4925 | Yes | ||
| 27 | CNTFR | ENSG00000122756.15 | 4172 | 1.100 | 0.4884 | Yes | ||
| 28 | OSMR | ENSG00000145623.13 | 4521 | 1.041 | 0.4921 | Yes | ||
| 29 | IFNGR1 | ENSG00000027697.14 | 4559 | 1.035 | 0.5029 | Yes | ||
| 30 | ITGA4 | ENSG00000115232.14 | 5278 | 0.930 | 0.4968 | No | ||
| 31 | SOCS1 | ENSG00000185338.5 | 5891 | 0.854 | 0.4922 | No | ||
| 32 | STAT3 | ENSG00000168610.14 | 6173 | 0.820 | 0.4950 | No | ||
| 33 | CCR1 | ENSG00000163823.4 | 6476 | 0.790 | 0.4969 | No | ||
| 34 | PLA2G2A | ENSG00000188257.11 | 6932 | 0.744 | 0.4948 | No | ||
| 35 | CD38 | ENSG00000004468.13 | 8415 | 0.611 | 0.4673 | No | ||
| 36 | TLR2 | ENSG00000137462.8 | 9313 | 0.549 | 0.4527 | No | ||
| 37 | CSF3R | ENSG00000119535.17 | 9393 | 0.544 | 0.4570 | No | ||
| 38 | CXCL9 | ENSG00000138755.6 | 9551 | 0.534 | 0.4594 | No | ||
| 39 | HMOX1 | ENSG00000100292.17 | 9579 | 0.532 | 0.4648 | No | ||
| 40 | IL2RA | ENSG00000134460.17 | 9914 | 0.516 | 0.4629 | No | ||
| 41 | ACVR1B | ENSG00000135503.13 | 10636 | 0.469 | 0.4514 | No | ||
| 42 | IL18R1 | ENSG00000115604.10 | 11692 | 0.402 | 0.4315 | No | ||
| 43 | CSF2RB | ENSG00000100368.14 | 14043 | 0.314 | 0.3804 | No | ||
| 44 | PIM1 | ENSG00000137193.14 | 16645 | 0.213 | 0.3224 | No | ||
| 45 | IL12RB1 | ENSG00000096996.16 | 16657 | 0.212 | 0.3246 | No | ||
| 46 | CXCL1 | ENSG00000163739.5 | 17045 | 0.196 | 0.3178 | No | ||
| 47 | IL1B | ENSG00000125538.12 | 17487 | 0.172 | 0.3095 | No | ||
| 48 | CXCL11 | ENSG00000169248.13 | 18808 | 0.107 | 0.2800 | No | ||
| 49 | PDGFC | ENSG00000145431.11 | 20731 | 0.011 | 0.2355 | No | ||
| 50 | PTPN2 | ENSG00000175354.20 | 21440 | -0.029 | 0.2194 | No | ||
| 51 | A2M | ENSG00000175899.14 | 21664 | -0.040 | 0.2146 | No | ||
| 52 | AC005840.1 | ENSG00000213942.3 | 22238 | -0.071 | 0.2021 | No | ||
| 53 | EBI3 | ENSG00000105246.6 | 23348 | -0.132 | 0.1779 | No | ||
| 54 | PIK3R5 | ENSG00000141506.13 | 23567 | -0.145 | 0.1744 | No | ||
| 55 | DNTT | ENSG00000107447.8 | 23612 | -0.147 | 0.1751 | No | ||
| 56 | MAP3K8 | ENSG00000107968.10 | 23988 | -0.170 | 0.1683 | No | ||
| 57 | LEPR | ENSG00000116678.19 | 24076 | -0.175 | 0.1683 | No | ||
| 58 | STAM2 | ENSG00000115145.10 | 26463 | -0.263 | 0.1158 | No | ||
| 59 | HAX1 | ENSG00000143575.14 | 26609 | -0.274 | 0.1155 | No | ||
| 60 | CBL | ENSG00000110395.6 | 28190 | -0.323 | 0.0825 | No | ||
| 61 | CXCL10 | ENSG00000169245.6 | 29765 | -0.392 | 0.0504 | No | ||
| 62 | LTB | ENSG00000227507.2 | 30077 | -0.411 | 0.0478 | No | ||
| 63 | ITGB3 | ENSG00000259207.7 | 31330 | -0.481 | 0.0241 | No | ||
| 64 | TNFRSF21 | ENSG00000146072.6 | 31612 | -0.495 | 0.0232 | No | ||
| 65 | TYK2 | ENSG00000105397.14 | 32192 | -0.526 | 0.0157 | No | ||
| 66 | CXCL3 | ENSG00000163734.4 | 32436 | -0.541 | 0.0162 | No | ||
| 67 | SOCS3 | ENSG00000184557.4 | 34239 | -0.677 | -0.0180 | No | ||
| 68 | CXCL13 | ENSG00000156234.7 | 34771 | -0.721 | -0.0221 | No | ||
| 69 | PF4 | ENSG00000163737.4 | 34978 | -0.739 | -0.0186 | No | ||
| 70 | IL4R | ENSG00000077238.14 | 35619 | -0.801 | -0.0244 | No | ||
| 71 | BAK1 | ENSG00000030110.13 | 35677 | -0.806 | -0.0165 | No | ||
| 72 | JUN | ENSG00000177606.7 | 37141 | -0.985 | -0.0394 | No | ||
| 73 | IL6 | ENSG00000136244.12 | 37366 | -1.015 | -0.0331 | No | ||
| 74 | TNF | ENSG00000232810.4 | 37586 | -1.048 | -0.0263 | No | ||
| 75 | PTPN11 | ENSG00000179295.17 | 37966 | -1.112 | -0.0225 | No | ||
| 76 | TGFB1 | ENSG00000105329.10 | 38478 | -1.201 | -0.0208 | No | ||
| 77 | GRB2 | ENSG00000177885.15 | 39308 | -1.380 | -0.0244 | No | ||
| 78 | PTPN1 | ENSG00000196396.10 | 40036 | -1.557 | -0.0237 | No | ||
| 79 | CSF2 | ENSG00000164400.6 | 40320 | -1.633 | -0.0118 | No | ||
| 80 | TNFRSF12A | ENSG00000006327.13 | 41188 | -1.954 | -0.0098 | No | ||
| 81 | IL2RG | ENSG00000147168.12 | 41862 | -2.374 | 0.0015 | No | ||
| 82 | INHBE | ENSG00000139269.3 | 41941 | -2.445 | 0.0274 | No |
