Details for gene set HALLMARK_INFLAMMATORY_RESPONSE[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2M
GeneSet	HALLMARK_INFLAMMATORY_RESPONSE
Enrichment Score (ES)	-0.29006374
Normalized Enrichment Score (NES)	-1.1721628
Nominal p-value	0.15086782
FDR q-value	0.22473446
FWER p-Value	0.997

Fig 1: Enrichment plot: HALLMARK_INFLAMMATORY_RESPONSE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ADM	ENSG00000148926.10			19	4.384	0.0178	No
2	P2RX7	ENSG00000089041.17			22	4.375	0.0359	No
3	LPAR1	ENSG00000198121.13			173	3.367	0.0464	No
4	SLC1A2	ENSG00000110436.13			232	3.201	0.0584	No
5	TPBG	ENSG00000146242.8			331	2.893	0.0681	No
6	PTGIR	ENSG00000160013.9			333	2.886	0.0801	No
7	SCARF1	ENSG00000074660.16			360	2.840	0.0913	No
8	P2RX4	ENSG00000135124.14			481	2.631	0.0995	No
9	AHR	ENSG00000106546.14			498	2.602	0.1099	No
10	IL1R1	ENSG00000115594.12			542	2.559	0.1195	No
11	TIMP1	ENSG00000102265.12			582	2.491	0.1290	No
12	IFNGR2	ENSG00000159128.14			882	2.184	0.1311	No
13	IFITM1	ENSG00000185885.16			887	2.182	0.1401	No
14	RTP4	ENSG00000136514.3			888	2.182	0.1491	No
15	LDLR	ENSG00000130164.13			900	2.174	0.1579	No
16	LY6E	ENSG00000160932.11			924	2.150	0.1663	No
17	CHST2	ENSG00000175040.6			1311	1.932	0.1654	No
18	GPR132	ENSG00000183484.12			1315	1.930	0.1733	No
19	IFNAR1	ENSG00000142166.13			1384	1.890	0.1796	No
20	IL15RA	ENSG00000134470.21			1434	1.873	0.1862	No
21	TACR1	ENSG00000115353.11			1567	1.814	0.1907	No
22	CD14	ENSG00000170458.14			1584	1.809	0.1979	No
23	TNFRSF1B	ENSG00000028137.19			1790	1.722	0.2002	No
24	TLR3	ENSG00000164342.12			2177	1.573	0.1978	No
25	CSF1	ENSG00000184371.14			2219	1.559	0.2033	No
26	RHOG	ENSG00000177105.10			2462	1.485	0.2039	No
27	MXD1	ENSG00000059728.11			2648	1.427	0.2055	No
28	IRAK2	ENSG00000134070.5			2876	1.361	0.2058	No
29	EMP3	ENSG00000142227.11			2904	1.355	0.2109	No
30	HRH1	ENSG00000196639.6			3030	1.327	0.2135	No
31	CCL7	ENSG00000108688.11			3096	1.310	0.2174	No
32	RASGRP1	ENSG00000172575.12			3180	1.292	0.2208	No
33	KLF6	ENSG00000067082.15			3324	1.262	0.2227	No
34	IRF1	ENSG00000125347.14			3458	1.235	0.2248	No
35	ABCA1	ENSG00000165029.16			3576	1.212	0.2271	No
36	ITGB8	ENSG00000105855.10			3741	1.176	0.2282	No
37	TNFSF10	ENSG00000121858.11			3755	1.173	0.2327	No
38	EIF2AK2	ENSG00000055332.18			4061	1.118	0.2303	No
39	NAMPT	ENSG00000105835.12			4118	1.109	0.2336	No
40	KCNA3	ENSG00000177272.9			4151	1.103	0.2374	No
41	ICAM1	ENSG00000090339.9			4204	1.093	0.2408	No
42	OSMR	ENSG00000145623.13			4521	1.041	0.2377	No
43	TNFSF9	ENSG00000125657.5			4548	1.036	0.2414	No
44	BEST1	ENSG00000167995.16			4619	1.026	0.2441	No
45	CX3CL1	ENSG00000006210.7			4796	0.999	0.2441	No
46	SELL	ENSG00000188404.10			4919	0.981	0.2453	No
47	EREG	ENSG00000124882.4			4928	0.979	0.2492	No
48	GP1BA	ENSG00000185245.8			5108	0.953	0.2490	No
49	CD55	ENSG00000196352.15			5115	0.952	0.2528	No
50	PDE4B	ENSG00000184588.18			5193	0.941	0.2550	No
51	SLC11A2	ENSG00000110911.16			5394	0.914	0.2541	No
52	CXCL6	ENSG00000124875.10			5459	0.905	0.2564	No
53	AQP9	ENSG00000103569.10			5524	0.897	0.2586	No
54	GNA15	ENSG00000060558.4			5581	0.890	0.2610	No
55	CCR7	ENSG00000126353.3			6031	0.837	0.2540	No
56	GABBR1	ENSG00000204681.11			6088	0.830	0.2562	No
57	NFKB1	ENSG00000109320.13			6111	0.828	0.2591	No
58	IL15	ENSG00000164136.17			6136	0.824	0.2620	No
59	TAPBP	ENSG00000231925.11			6179	0.819	0.2644	No
60	NLRP3	ENSG00000162711.17			6212	0.815	0.2670	No
61	GPC3	ENSG00000147257.14			6374	0.800	0.2666	No
62	IL2RB	ENSG00000100385.14			6472	0.790	0.2676	No
63	SRI	ENSG00000075142.13			6706	0.767	0.2654	No
64	IL18	ENSG00000150782.12			6797	0.757	0.2665	No
65	OLR1	ENSG00000173391.9			7038	0.734	0.2639	No
66	IL18RAP	ENSG00000115607.9			7077	0.730	0.2661	No
67	GCH1	ENSG00000131979.19			7161	0.723	0.2671	No
68	NMI	ENSG00000123609.11			7263	0.713	0.2677	No
69	CCL2	ENSG00000108691.9			7391	0.701	0.2677	No
70	GNAI3	ENSG00000065135.11			7451	0.695	0.2692	No
71	PTGER4	ENSG00000171522.6			7713	0.671	0.2659	No
72	CD40	ENSG00000101017.14			8044	0.644	0.2609	No
73	SPHK1	ENSG00000176170.13			8512	0.605	0.2526	No
74	MSR1	ENSG00000038945.15			8615	0.598	0.2527	No
75	CCL5	ENSG00000271503.6			8798	0.583	0.2508	No
76	TLR2	ENSG00000137462.8			9313	0.549	0.2412	No
77	ATP2C1	ENSG00000017260.19			9381	0.545	0.2419	No
78	CSF3R	ENSG00000119535.17			9393	0.544	0.2439	No
79	MMP14	ENSG00000157227.13			9489	0.539	0.2439	No
80	CXCL9	ENSG00000138755.6			9551	0.534	0.2447	No
81	ADGRE1	ENSG00000174837.15			9975	0.514	0.2370	No
82	IL1A	ENSG00000115008.5			10008	0.511	0.2384	No
83	NFKBIA	ENSG00000100906.10			10473	0.480	0.2295	No
84	ACVR1B	ENSG00000135503.13			10636	0.469	0.2277	No
85	LYN	ENSG00000254087.8			10784	0.460	0.2262	No
86	LCP2	ENSG00000043462.12			11106	0.438	0.2205	No
87	F3	ENSG00000117525.14			11227	0.431	0.2195	No
88	IL18R1	ENSG00000115604.10			11692	0.402	0.2104	No
89	SELENOS	ENSG00000131871.15			11752	0.400	0.2107	No
90	SCN1B	ENSG00000105711.12			12081	0.383	0.2046	No
91	OPRK1	ENSG00000082556.12			13126	0.350	0.1818	No
92	PROK2	ENSG00000163421.9			13853	0.322	0.1662	No
93	PDPN	ENSG00000162493.16			14099	0.311	0.1618	No
94	IRF7	ENSG00000185507.21			14110	0.311	0.1628	No
95	PTGER2	ENSG00000125384.7			14137	0.308	0.1635	No
96	C5AR1	ENSG00000197405.8			14141	0.308	0.1647	No
97	LCK	ENSG00000182866.17			15496	0.275	0.1343	No
98	KCNMB2	ENSG00000197584.12			15516	0.274	0.1350	No
99	HPN	ENSG00000105707.14			15619	0.269	0.1338	No
100	BST2	ENSG00000130303.13			15884	0.255	0.1287	No
101	AXL	ENSG00000167601.12			16332	0.229	0.1192	No
102	IL1B	ENSG00000125538.12			17487	0.172	0.0930	No
103	ADORA2B	ENSG00000170425.3			17637	0.167	0.0903	No
104	CCL24	ENSG00000106178.6			17988	0.147	0.0827	No
105	PTAFR	ENSG00000169403.12			18599	0.119	0.0690	No
106	CXCL11	ENSG00000169248.13			18808	0.107	0.0646	No
107	RELA	ENSG00000173039.19			18880	0.104	0.0634	No
108	NPFFR2	ENSG00000056291.17			19493	0.072	0.0494	No
109	PSEN1	ENSG00000080815.19			20272	0.034	0.0314	No
110	SLC31A1	ENSG00000136868.11			20696	0.013	0.0216	No
111	APLNR	ENSG00000134817.10			21199	-0.016	0.0100	No
112	DCBLD2	ENSG00000057019.16			21563	-0.035	0.0017	No
113	CD70	ENSG00000125726.11			22197	-0.068	-0.0128	No
114	IL12B	ENSG00000113302.4			22283	-0.073	-0.0144	No
115	ACVR2A	ENSG00000121989.15			22689	-0.096	-0.0235	No
116	IL7R	ENSG00000168685.15			23218	-0.125	-0.0353	No
117	EBI3	ENSG00000105246.6			23348	-0.132	-0.0377	No
118	PIK3R5	ENSG00000141506.13			23567	-0.145	-0.0422	No
119	MARCO	ENSG00000019169.10			23874	-0.163	-0.0487	No
120	RIPK2	ENSG00000104312.8			24469	-0.197	-0.0617	No
121	CXCR6	ENSG00000172215.6			24683	-0.210	-0.0658	No
122	FFAR2	ENSG00000126262.4			25009	-0.223	-0.0724	No
123	SEMA4D	ENSG00000187764.11			25560	-0.231	-0.0843	No
124	NMUR1	ENSG00000171596.7			25637	-0.236	-0.0850	No
125	CD69	ENSG00000110848.8			26251	-0.263	-0.0982	No
126	MEP1A	ENSG00000112818.10			26323	-0.263	-0.0988	No
127	SLC28A2	ENSG00000137860.12			28192	-0.323	-0.1410	No
128	CLEC5A	ENSG00000258227.7			29424	-0.370	-0.1681	No
129	STAB1	ENSG00000010327.10			29747	-0.390	-0.1740	No
130	CXCL10	ENSG00000169245.6			29765	-0.392	-0.1728	No
131	SGMS2	ENSG00000164023.14			29947	-0.403	-0.1753	No
132	CCL22	ENSG00000102962.5			30346	-0.429	-0.1828	No
133	CMKLR1	ENSG00000174600.14			30724	-0.448	-0.1897	No
134	ITGB3	ENSG00000259207.7			31330	-0.481	-0.2018	No
135	BDKRB1	ENSG00000100739.11			31357	-0.483	-0.2004	No
136	CCL17	ENSG00000102970.11			31912	-0.509	-0.2112	No
137	SELE	ENSG00000007908.16			32444	-0.541	-0.2213	No
138	RAF1	ENSG00000132155.11			32694	-0.559	-0.2248	No
139	KCNJ2	ENSG00000123700.4			32768	-0.566	-0.2241	No
140	PCDH7	ENSG00000169851.15			34101	-0.667	-0.2524	No
141	VIP	ENSG00000146469.13			34186	-0.675	-0.2515	No
142	LTA	ENSG00000226979.8			35231	-0.762	-0.2727	No
143	MYC	ENSG00000136997.19			35251	-0.763	-0.2700	No
144	IL4R	ENSG00000077238.14			35619	-0.801	-0.2752	No
145	NDP	ENSG00000124479.11			35951	-0.838	-0.2794	No
146	RGS16	ENSG00000143333.7			36334	-0.882	-0.2847	No
147	IL10RA	ENSG00000110324.10			36391	-0.887	-0.2823	No
148	TACR3	ENSG00000169836.5			36611	-0.917	-0.2836	No
149	OSM	ENSG00000099985.4			36846	-0.947	-0.2851	No
150	CD48	ENSG00000117091.10			37061	-0.976	-0.2860	Yes
151	BTG2	ENSG00000159388.6			37157	-0.987	-0.2841	Yes
152	ADRM1	ENSG00000130706.13			37285	-1.005	-0.2829	Yes
153	IL6	ENSG00000136244.12			37366	-1.015	-0.2805	Yes
154	TNFAIP6	ENSG00000123610.5			37407	-1.021	-0.2772	Yes
155	CDKN1A	ENSG00000124762.13			37465	-1.029	-0.2743	Yes
156	TLR1	ENSG00000174125.8			37664	-1.061	-0.2745	Yes
157	ABI1	ENSG00000136754.17			37724	-1.071	-0.2714	Yes
158	HIF1A	ENSG00000100644.17			37783	-1.081	-0.2683	Yes
159	CCL20	ENSG00000115009.13			37860	-1.093	-0.2655	Yes
160	CXCL8	ENSG00000169429.11			37884	-1.098	-0.2615	Yes
161	CYBB	ENSG00000165168.7			37925	-1.105	-0.2578	Yes
162	ICOSLG	ENSG00000160223.17			38080	-1.131	-0.2567	Yes
163	SERPINE1	ENSG00000106366.8			38403	-1.189	-0.2592	Yes
164	LAMP3	ENSG00000078081.8			38690	-1.241	-0.2607	Yes
165	MET	ENSG00000105976.15			39028	-1.316	-0.2631	Yes
166	PTPRE	ENSG00000132334.16			39641	-1.452	-0.2713	Yes
167	CALCRL	ENSG00000064989.13			39870	-1.513	-0.2704	Yes
168	EDN1	ENSG00000078401.7			39917	-1.527	-0.2651	Yes
169	ATP2B1	ENSG00000070961.15			40174	-1.593	-0.2644	Yes
170	ITGA5	ENSG00000161638.11			40419	-1.662	-0.2632	Yes
171	MEFV	ENSG00000103313.12			40494	-1.686	-0.2579	Yes
172	P2RY2	ENSG00000175591.11			40519	-1.694	-0.2514	Yes
173	SLC31A2	ENSG00000136867.11			40590	-1.714	-0.2459	Yes
174	SLC7A1	ENSG00000139514.13			40707	-1.750	-0.2414	Yes
175	GPR183	ENSG00000169508.7			41040	-1.884	-0.2413	Yes
176	PLAUR	ENSG00000011422.12			41170	-1.945	-0.2362	Yes
177	CCRL2	ENSG00000121797.10			41412	-2.072	-0.2332	Yes
178	INHBA	ENSG00000122641.11			41421	-2.082	-0.2247	Yes
179	RGS1	ENSG00000090104.12			41652	-2.222	-0.2208	Yes
180	TNFRSF9	ENSG00000049249.8			41845	-2.364	-0.2155	Yes
181	SLC7A2	ENSG00000003989.17			41914	-2.420	-0.2070	Yes
182	CSF3	ENSG00000108342.12			42130	-2.616	-0.2011	Yes
183	ATP2A2	ENSG00000174437.17			42170	-2.663	-0.1910	Yes
184	FZD5	ENSG00000163251.4			42233	-2.747	-0.1810	Yes
185	C3AR1	ENSG00000171860.5			42263	-2.787	-0.1701	Yes
186	HAS2	ENSG00000170961.7			42403	-2.985	-0.1609	Yes
187	PVR	ENSG00000073008.15			42407	-2.989	-0.1485	Yes
188	TNFSF15	ENSG00000181634.8			42478	-3.101	-0.1373	Yes
189	RNF144B	ENSG00000137393.9			42503	-3.129	-0.1248	Yes
190	SLC4A4	ENSG00000080493.17			42558	-3.226	-0.1127	Yes
191	KIF1B	ENSG00000054523.17			42584	-3.294	-0.0996	Yes
192	ROS1	ENSG00000047936.10			42683	-3.542	-0.0871	Yes
193	FPR1	ENSG00000171051.8			42753	-3.730	-0.0732	Yes
194	IL10	ENSG00000136634.7			42757	-3.743	-0.0577	Yes
195	CD82	ENSG00000085117.12			42768	-3.776	-0.0423	Yes
196	NOD2	ENSG00000167207.13			42814	-3.963	-0.0268	Yes
197	HBEGF	ENSG00000113070.8			42836	-4.053	-0.0105	Yes
198	LIF	ENSG00000128342.5			42847	-4.098	0.0063	Yes

Fig 2: HALLMARK_INFLAMMATORY_RESPONSE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_INFLAMMATORY_RESPONSE: Random ES distribution   
Gene set null distribution of ES for HALLMARK_INFLAMMATORY_RESPONSE