Details for gene set HALLMARK_INTERFERON_ALPHA_RESPONSE[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2
GeneSet	HALLMARK_INTERFERON_ALPHA_RESPONSE
Enrichment Score (ES)	0.6673027
Normalized Enrichment Score (NES)	2.7189841
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: HALLMARK_INTERFERON_ALPHA_RESPONSE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	C1S	ENSG00000182326.15			34	4.267	0.0311	Yes
2	DHX58	ENSG00000108771.13			136	3.540	0.0552	Yes
3	IL7	ENSG00000104432.14			187	3.332	0.0789	Yes
4	UBE2L6	ENSG00000156587.16			391	2.767	0.0949	Yes
5	HELZ2	ENSG00000130589.16			462	2.659	0.1131	Yes
6	IFIT2	ENSG00000119922.10			471	2.644	0.1327	Yes
7	PARP14	ENSG00000173193.15			494	2.613	0.1517	Yes
8	UBA7	ENSG00000182179.13			500	2.599	0.1710	Yes
9	IFI35	ENSG00000068079.7			607	2.461	0.1869	Yes
10	PSMB9	ENSG00000240065.8			653	2.409	0.2038	Yes
11	PARP9	ENSG00000138496.16			756	2.302	0.2187	Yes
12	IFITM2	ENSG00000185201.16			775	2.288	0.2353	Yes
13	IFITM3	ENSG00000142089.16			861	2.207	0.2499	Yes
14	IFITM1	ENSG00000185885.16			887	2.182	0.2656	Yes
15	RTP4	ENSG00000136514.3			888	2.182	0.2819	Yes
16	B2M	ENSG00000166710.20			923	2.152	0.2972	Yes
17	LY6E	ENSG00000160932.11			924	2.150	0.3132	Yes
18	PROCR	ENSG00000101000.6			990	2.109	0.3275	Yes
19	PSMB8	ENSG00000204264.11			1023	2.095	0.3424	Yes
20	PLSCR1	ENSG00000188313.13			1031	2.090	0.3578	Yes
21	STAT2	ENSG00000170581.14			1323	1.925	0.3654	Yes
22	TRIM21	ENSG00000132109.10			1467	1.856	0.3760	Yes
23	CD47	ENSG00000196776.16			1555	1.816	0.3875	Yes
24	NCOA7	ENSG00000111912.20			1579	1.811	0.4005	Yes
25	IRF2	ENSG00000168310.11			1700	1.754	0.4108	Yes
26	TRIM25	ENSG00000121060.18			1739	1.741	0.4229	Yes
27	SP110	ENSG00000135899.17			1845	1.694	0.4332	Yes
28	BATF2	ENSG00000168062.10			1850	1.692	0.4457	Yes
29	IFIH1	ENSG00000115267.8			1866	1.683	0.4579	Yes
30	TENT5A	ENSG00000112773.16			1920	1.660	0.4691	Yes
31	OGFR	ENSG00000060491.16			2058	1.610	0.4779	Yes
32	IFIT3	ENSG00000119917.14			2102	1.598	0.4889	Yes
33	TMEM140	ENSG00000146859.6			2187	1.571	0.4987	Yes
34	CSF1	ENSG00000184371.14			2219	1.559	0.5096	Yes
35	IFI44	ENSG00000137965.11			2233	1.554	0.5209	Yes
36	ELF1	ENSG00000120690.16			2323	1.527	0.5302	Yes
37	HERC6	ENSG00000138642.14			2429	1.497	0.5390	Yes
38	IFI44L	ENSG00000137959.16			2506	1.473	0.5482	Yes
39	DDX60	ENSG00000137628.17			2522	1.466	0.5588	Yes
40	CMPK2	ENSG00000134326.11			2649	1.426	0.5665	Yes
41	ADAR	ENSG00000160710.17			2750	1.394	0.5746	Yes
42	CASP1	ENSG00000137752.24			2840	1.369	0.5828	Yes
43	MOV10	ENSG00000155363.18			2889	1.359	0.5918	Yes
44	HLA-C	ENSG00000204525.16			2999	1.333	0.5993	Yes
45	ISG20	ENSG00000172183.15			3169	1.296	0.6050	Yes
46	IRF9	ENSG00000213928.9			3253	1.277	0.6126	Yes
47	IRF1	ENSG00000125347.14			3458	1.235	0.6171	Yes
48	TRIM26	ENSG00000234127.9			3692	1.187	0.6205	Yes
49	PARP12	ENSG00000059378.12			3942	1.139	0.6233	Yes
50	GBP4	ENSG00000162654.9			4028	1.122	0.6297	Yes
51	EIF2AK2	ENSG00000055332.18			4061	1.118	0.6373	Yes
52	RSAD2	ENSG00000134321.12			4081	1.115	0.6452	Yes
53	MX1	ENSG00000157601.14			4253	1.082	0.6493	Yes
54	RNF31	ENSG00000092098.17			4683	1.017	0.6469	Yes
55	ISG15	ENSG00000187608.10			4739	1.008	0.6532	Yes
56	CD74	ENSG00000019582.15			4804	0.997	0.6591	Yes
57	SELL	ENSG00000188404.10			4919	0.981	0.6638	Yes
58	IFI27	ENSG00000165949.12			5347	0.921	0.6607	Yes
59	TDRD7	ENSG00000196116.8			5361	0.919	0.6673	Yes
60	IL15	ENSG00000164136.17			6136	0.824	0.6555	No
61	TRIM14	ENSG00000106785.15			6486	0.789	0.6533	No
62	MVB12A	ENSG00000141971.13			6696	0.768	0.6541	No
63	OASL	ENSG00000135114.12			7140	0.724	0.6492	No
64	EPSTI1	ENSG00000133106.14			7221	0.716	0.6527	No
65	NMI	ENSG00000123609.11			7263	0.713	0.6571	No
66	CASP8	ENSG00000064012.21			7888	0.656	0.6475	No
67	SLC25A28	ENSG00000155287.11			8738	0.588	0.6322	No
68	CNP	ENSG00000173786.17			8781	0.585	0.6356	No
69	LPAR6	ENSG00000139679.15			10066	0.507	0.6095	No
70	NUB1	ENSG00000013374.16			12716	0.360	0.5506	No
71	SAMD9L	ENSG00000177409.12			13432	0.331	0.5365	No
72	TAP1	ENSG00000168394.11			14010	0.316	0.5254	No
73	IRF7	ENSG00000185507.21			14110	0.311	0.5254	No
74	AC004551.1	ENSG00000257452.1			14760	0.294	0.5126	No
75	SAMD9	ENSG00000205413.8			15501	0.275	0.4974	No
76	BST2	ENSG00000130303.13			15884	0.255	0.4904	No
77	PSME1	ENSG00000092010.15			17744	0.161	0.4484	No
78	CXCL11	ENSG00000169248.13			18808	0.107	0.4245	No
79	TRIM5	ENSG00000132256.19			23106	-0.119	0.3255	No
80	RIPK2	ENSG00000104312.8			24469	-0.197	0.2953	No
81	CMTR1	ENSG00000137200.13			27192	-0.287	0.2342	No
82	IFI30	ENSG00000216490.4			29746	-0.390	0.1778	No
83	CXCL10	ENSG00000169245.6			29765	-0.392	0.1803	No
84	LAP3	ENSG00000002549.12			29880	-0.396	0.1806	No
85	PSMA3	ENSG00000100567.13			31911	-0.509	0.1372	No
86	PSME2	ENSG00000100911.16			33632	-0.632	0.1020	No
87	IL4R	ENSG00000077238.14			35619	-0.801	0.0618	No
88	TXNIP	ENSG00000265972.6			36595	-0.913	0.0460	No
89	WARS	ENSG00000140105.18			37336	-1.011	0.0363	No
90	LGALS3BP	ENSG00000108679.13			37914	-1.103	0.0311	No
91	LAMP3	ENSG00000078081.8			38690	-1.241	0.0224	No
92	GBP2	ENSG00000162645.13			39071	-1.325	0.0235	No
93	PNPT1	ENSG00000138035.15			39282	-1.372	0.0288	No
94	USP18	ENSG00000184979.10			40364	-1.644	0.0160	No
95	TRAFD1	ENSG00000135148.12			41030	-1.879	0.0146	No
96	CCRL2	ENSG00000121797.10			41412	-2.072	0.0212	No
97	GMPR	ENSG00000137198.10			41978	-2.473	0.0265	No

Fig 2: HALLMARK_INTERFERON_ALPHA_RESPONSE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_INTERFERON_ALPHA_RESPONSE: Random ES distribution   
Gene set null distribution of ES for HALLMARK_INTERFERON_ALPHA_RESPONSE