Details for gene set HALLMARK_INTERFERON_GAMMA_RESPONSE[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2
GeneSet	HALLMARK_INTERFERON_GAMMA_RESPONSE
Enrichment Score (ES)	0.47539985
Normalized Enrichment Score (NES)	2.144124
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: HALLMARK_INTERFERON_GAMMA_RESPONSE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	C1S	ENSG00000182326.15			34	4.267	0.0167	Yes
2	DHX58	ENSG00000108771.13			136	3.540	0.0288	Yes
3	IL7	ENSG00000104432.14			187	3.332	0.0412	Yes
4	CFB	ENSG00000243649.8			196	3.306	0.0546	Yes
5	C1R	ENSG00000159403.18			251	3.121	0.0661	Yes
6	UBE2L6	ENSG00000156587.16			391	2.767	0.0741	Yes
7	HELZ2	ENSG00000130589.16			462	2.659	0.0834	Yes
8	IFIT2	ENSG00000119922.10			471	2.644	0.0940	Yes
9	PARP14	ENSG00000173193.15			494	2.613	0.1042	Yes
10	IFI35	ENSG00000068079.7			607	2.461	0.1116	Yes
11	PSMB9	ENSG00000240065.8			653	2.409	0.1204	Yes
12	IFITM2	ENSG00000185201.16			775	2.288	0.1270	Yes
13	IFITM3	ENSG00000142089.16			861	2.207	0.1340	Yes
14	RTP4	ENSG00000136514.3			888	2.182	0.1423	Yes
15	ARID5B	ENSG00000150347.16			891	2.179	0.1512	Yes
16	HLA-DMA	ENSG00000204257.15			906	2.165	0.1597	Yes
17	FAS	ENSG00000026103.22			911	2.164	0.1685	Yes
18	B2M	ENSG00000166710.20			923	2.152	0.1770	Yes
19	LY6E	ENSG00000160932.11			924	2.150	0.1858	Yes
20	HLA-B	ENSG00000234745.11			962	2.126	0.1936	Yes
21	PSMB8	ENSG00000204264.11			1023	2.095	0.2008	Yes
22	PLSCR1	ENSG00000188313.13			1031	2.090	0.2092	Yes
23	UPP1	ENSG00000183696.14			1170	2.007	0.2142	Yes
24	ST3GAL5	ENSG00000115525.18			1234	1.973	0.2208	Yes
25	RAPGEF6	ENSG00000158987.21			1255	1.961	0.2283	Yes
26	STAT2	ENSG00000170581.14			1323	1.925	0.2347	Yes
27	STAT1	ENSG00000115415.18			1379	1.893	0.2411	Yes
28	IL15RA	ENSG00000134470.21			1434	1.873	0.2475	Yes
29	TRIM21	ENSG00000132109.10			1467	1.856	0.2544	Yes
30	IRF2	ENSG00000168310.11			1700	1.754	0.2561	Yes
31	TRIM25	ENSG00000121060.18			1739	1.741	0.2624	Yes
32	SAMHD1	ENSG00000101347.9			1794	1.720	0.2681	Yes
33	SP110	ENSG00000135899.17			1845	1.694	0.2739	Yes
34	BATF2	ENSG00000168062.10			1850	1.692	0.2807	Yes
35	APOL6	ENSG00000221963.6			1861	1.686	0.2874	Yes
36	IFIH1	ENSG00000115267.8			1866	1.683	0.2942	Yes
37	MX2	ENSG00000183486.13			1946	1.652	0.2991	Yes
38	OGFR	ENSG00000060491.16			2058	1.610	0.3031	Yes
39	IFIT3	ENSG00000119917.14			2102	1.598	0.3086	Yes
40	IFI44	ENSG00000137965.11			2233	1.554	0.3120	Yes
41	CASP4	ENSG00000196954.14			2254	1.548	0.3178	Yes
42	MYD88	ENSG00000172936.14			2301	1.535	0.3230	Yes
43	PML	ENSG00000140464.20			2373	1.513	0.3276	Yes
44	HERC6	ENSG00000138642.14			2429	1.497	0.3324	Yes
45	IFI44L	ENSG00000137959.16			2506	1.473	0.3366	Yes
46	DDX60	ENSG00000137628.17			2522	1.466	0.3423	Yes
47	CMPK2	ENSG00000134326.11			2649	1.426	0.3452	Yes
48	ADAR	ENSG00000160710.17			2750	1.394	0.3486	Yes
49	PTGS2	ENSG00000073756.12			2837	1.370	0.3522	Yes
50	CASP1	ENSG00000137752.24			2840	1.369	0.3577	Yes
51	OAS2	ENSG00000111335.12			2849	1.367	0.3631	Yes
52	RIPK1	ENSG00000137275.14			2864	1.362	0.3684	Yes
53	IFIT1	ENSG00000185745.10			2918	1.351	0.3726	Yes
54	PSMB10	ENSG00000205220.12			3086	1.313	0.3741	Yes
55	SERPING1	ENSG00000149131.15			3087	1.313	0.3795	Yes
56	CCL7	ENSG00000108688.11			3096	1.310	0.3847	Yes
57	ISG20	ENSG00000172183.15			3169	1.296	0.3883	Yes
58	IRF9	ENSG00000213928.9			3253	1.277	0.3916	Yes
59	HLA-G	ENSG00000204632.11			3266	1.274	0.3965	Yes
60	IRF1	ENSG00000125347.14			3458	1.235	0.3971	Yes
61	TRIM26	ENSG00000234127.9			3692	1.187	0.3965	Yes
62	TNFSF10	ENSG00000121858.11			3755	1.173	0.3999	Yes
63	NLRC5	ENSG00000140853.15			3832	1.158	0.4028	Yes
64	PARP12	ENSG00000059378.12			3942	1.139	0.4050	Yes
65	EIF4E3	ENSG00000163412.13			4003	1.127	0.4082	Yes
66	GBP4	ENSG00000162654.9			4028	1.122	0.4122	Yes
67	EIF2AK2	ENSG00000055332.18			4061	1.118	0.4160	Yes
68	RSAD2	ENSG00000134321.12			4081	1.115	0.4201	Yes
69	NAMPT	ENSG00000105835.12			4118	1.109	0.4238	Yes
70	CIITA	ENSG00000179583.19			4142	1.105	0.4278	Yes
71	ICAM1	ENSG00000090339.9			4204	1.093	0.4309	Yes
72	MX1	ENSG00000157601.14			4253	1.082	0.4342	Yes
73	XCL1	ENSG00000143184.5			4293	1.078	0.4377	Yes
74	XAF1	ENSG00000132530.17			4303	1.076	0.4419	Yes
75	BANK1	ENSG00000153064.12			4466	1.050	0.4424	Yes
76	DDX58	ENSG00000107201.10			4602	1.028	0.4434	Yes
77	RNF31	ENSG00000092098.17			4683	1.017	0.4457	Yes
78	ISG15	ENSG00000187608.10			4739	1.008	0.4486	Yes
79	OAS3	ENSG00000111331.13			4756	1.006	0.4523	Yes
80	CD74	ENSG00000019582.15			4804	0.997	0.4553	Yes
81	TOR1B	ENSG00000136816.16			5132	0.950	0.4516	Yes
82	PDE4B	ENSG00000184588.18			5193	0.941	0.4540	Yes
83	IFI27	ENSG00000165949.12			5347	0.921	0.4542	Yes
84	TDRD7	ENSG00000196116.8			5361	0.919	0.4577	Yes
85	NCOA3	ENSG00000124151.19			5512	0.899	0.4578	Yes
86	SOCS1	ENSG00000185338.5			5891	0.854	0.4525	Yes
87	STAT4	ENSG00000138378.19			5947	0.847	0.4547	Yes
88	NFKB1	ENSG00000109320.13			6111	0.828	0.4543	Yes
89	IL15	ENSG00000164136.17			6136	0.824	0.4571	Yes
90	ZNFX1	ENSG00000124201.15			6139	0.824	0.4604	Yes
91	RBCK1	ENSG00000125826.20			6153	0.822	0.4635	Yes
92	STAT3	ENSG00000168610.14			6173	0.820	0.4664	Yes
93	TAPBP	ENSG00000231925.11			6179	0.819	0.4696	Yes
94	IL2RB	ENSG00000100385.14			6472	0.790	0.4661	Yes
95	TRIM14	ENSG00000106785.15			6486	0.789	0.4690	Yes
96	PLA2G4A	ENSG00000116711.10			6498	0.788	0.4720	Yes
97	SECTM1	ENSG00000141574.8			6705	0.767	0.4703	Yes
98	SRI	ENSG00000075142.13			6706	0.767	0.4734	Yes
99	IDO1	ENSG00000131203.13			6845	0.753	0.4733	Yes
100	OASL	ENSG00000135114.12			7140	0.724	0.4694	Yes
101	GCH1	ENSG00000131979.19			7161	0.723	0.4719	Yes
102	EPSTI1	ENSG00000133106.14			7221	0.716	0.4734	Yes
103	NMI	ENSG00000123609.11			7263	0.713	0.4754	Yes
104	CCL2	ENSG00000108691.9			7391	0.701	0.4753	No
105	CASP8	ENSG00000064012.21			7888	0.656	0.4664	No
106	CD40	ENSG00000101017.14			8044	0.644	0.4655	No
107	CFH	ENSG00000000971.15			8408	0.612	0.4595	No
108	CD38	ENSG00000004468.13			8415	0.611	0.4619	No
109	SLC25A28	ENSG00000155287.11			8738	0.588	0.4568	No
110	CCL5	ENSG00000271503.6			8798	0.583	0.4578	No
111	IRF4	ENSG00000137265.15			9062	0.567	0.4540	No
112	CXCL9	ENSG00000138755.6			9551	0.534	0.4448	No
113	LYSMD2	ENSG00000140280.14			9580	0.531	0.4463	No
114	P2RY14	ENSG00000174944.9			10440	0.482	0.4283	No
115	NFKBIA	ENSG00000100906.10			10473	0.480	0.4295	No
116	HLA-A	ENSG00000206503.13			10612	0.470	0.4282	No
117	LCP2	ENSG00000043462.12			11106	0.438	0.4185	No
118	HLA-DRB1	ENSG00000196126.11			11131	0.437	0.4197	No
119	SAMD9L	ENSG00000177409.12			13432	0.331	0.3675	No
120	TAP1	ENSG00000168394.11			14010	0.316	0.3553	No
121	CSF2RB	ENSG00000100368.14			14043	0.314	0.3559	No
122	IRF7	ENSG00000185507.21			14110	0.311	0.3556	No
123	BTG1	ENSG00000133639.5			14119	0.310	0.3567	No
124	FCGR1A	ENSG00000150337.13			14587	0.305	0.3470	No
125	AC124319.1	ENSG00000262979.1			14778	0.293	0.3438	No
126	FGL2	ENSG00000127951.7			14791	0.292	0.3447	No
127	BST2	ENSG00000130303.13			15884	0.255	0.3203	No
128	PSMA2	ENSG00000106588.11			16418	0.224	0.3088	No
129	PIM1	ENSG00000137193.14			16645	0.213	0.3044	No
130	PSME1	ENSG00000092010.15			17744	0.161	0.2795	No
131	PELI1	ENSG00000197329.12			17966	0.148	0.2750	No
132	NOD1	ENSG00000106100.11			18220	0.134	0.2696	No
133	CXCL11	ENSG00000169248.13			18808	0.107	0.2564	No
134	MVP	ENSG00000013364.19			19627	0.065	0.2376	No
135	IFNAR2	ENSG00000159110.19			20837	0.005	0.2094	No
136	PTPN2	ENSG00000175354.20			21440	-0.029	0.1955	No
137	CASP7	ENSG00000165806.20			23029	-0.113	0.1590	No
138	RIPK2	ENSG00000104312.8			24469	-0.197	0.1263	No
139	SOD2	ENSG00000112096.18			24563	-0.202	0.1249	No
140	GZMA	ENSG00000145649.8			25202	-0.223	0.1110	No
141	METTL7B	ENSG00000170439.7			25612	-0.234	0.1024	No
142	PFKP	ENSG00000067057.17			25775	-0.245	0.0996	No
143	CD69	ENSG00000110848.8			26251	-0.263	0.0896	No
144	SPPL2A	ENSG00000138600.10			27101	-0.281	0.0710	No
145	IRF5	ENSG00000128604.20			27146	-0.284	0.0711	No
146	CMTR1	ENSG00000137200.13			27192	-0.287	0.0713	No
147	IRF8	ENSG00000140968.11			28903	-0.351	0.0329	No
148	KLRK1	ENSG00000213809.9			29116	-0.354	0.0294	No
149	MT2A	ENSG00000125148.7			29124	-0.355	0.0307	No
150	CD86	ENSG00000114013.16			29238	-0.360	0.0295	No
151	LATS2	ENSG00000150457.9			29273	-0.361	0.0302	No
152	IFI30	ENSG00000216490.4			29746	-0.390	0.0208	No
153	CXCL10	ENSG00000169245.6			29765	-0.392	0.0220	No
154	LAP3	ENSG00000002549.12			29880	-0.396	0.0209	No
155	HLA-DQA1	ENSG00000196735.12			29924	-0.400	0.0216	No
156	GPR18	ENSG00000125245.12			30388	-0.431	0.0125	No
157	CMKLR1	ENSG00000174600.14			30724	-0.448	0.0066	No
158	MTHFD2	ENSG00000065911.12			31162	-0.472	-0.0017	No
159	JAK2	ENSG00000096968.13			31758	-0.501	-0.0135	No
160	PSMA3	ENSG00000100567.13			31911	-0.509	-0.0150	No
161	PSME2	ENSG00000100911.16			33632	-0.632	-0.0525	No
162	SOCS3	ENSG00000184557.4			34239	-0.677	-0.0638	No
163	PNP	ENSG00000198805.11			34508	-0.703	-0.0672	No
164	IL4R	ENSG00000077238.14			35619	-0.801	-0.0898	No
165	ISOC1	ENSG00000066583.12			35810	-0.819	-0.0908	No
166	PSMB2	ENSG00000126067.12			35837	-0.822	-0.0881	No
167	ITGB7	ENSG00000139626.16			36016	-0.846	-0.0888	No
168	IL10RA	ENSG00000110324.10			36391	-0.887	-0.0939	No
169	SELP	ENSG00000174175.17			36579	-0.910	-0.0945	No
170	TXNIP	ENSG00000265972.6			36595	-0.913	-0.0911	No
171	WARS	ENSG00000140105.18			37336	-1.011	-0.1042	No
172	IL6	ENSG00000136244.12			37366	-1.015	-0.1007	No
173	TNFAIP6	ENSG00000123610.5			37407	-1.021	-0.0975	No
174	CDKN1A	ENSG00000124762.13			37465	-1.029	-0.0946	No
175	HIF1A	ENSG00000100644.17			37783	-1.081	-0.0976	No
176	LGALS3BP	ENSG00000108679.13			37914	-1.103	-0.0961	No
177	PTPN6	ENSG00000111679.17			38407	-1.189	-0.1027	No
178	ZBP1	ENSG00000124256.15			39206	-1.355	-0.1157	No
179	PNPT1	ENSG00000138035.15			39282	-1.372	-0.1119	No
180	TNFAIP3	ENSG00000118503.15			39359	-1.390	-0.1080	No
181	BPGM	ENSG00000172331.12			39501	-1.423	-0.1054	No
182	PTPN1	ENSG00000196396.10			40036	-1.557	-0.1115	No
183	USP18	ENSG00000184979.10			40364	-1.644	-0.1124	No
184	SLAMF7	ENSG00000026751.17			40521	-1.694	-0.1091	No
185	IL18BP	ENSG00000137496.18			40697	-1.748	-0.1061	No
186	TNFAIP2	ENSG00000185215.9			40807	-1.787	-0.1013	No
187	CD274	ENSG00000120217.14			40999	-1.867	-0.0981	No
188	TRAFD1	ENSG00000135148.12			41030	-1.879	-0.0911	No
189	VCAM1	ENSG00000162692.12			41228	-1.969	-0.0877	No
190	ST8SIA4	ENSG00000113532.13			41479	-2.122	-0.0848	No
191	AUTS2	ENSG00000158321.18			41589	-2.188	-0.0784	No
192	ARL4A	ENSG00000122644.13			41707	-2.259	-0.0719	No
193	VAMP5	ENSG00000168899.5			42088	-2.559	-0.0703	No
194	CASP3	ENSG00000164305.19			42313	-2.869	-0.0638	No
195	MARCH1	ENSG00000145416.13			42380	-2.955	-0.0532	No
196	GBP6	ENSG00000183347.14			42400	-2.983	-0.0415	No
197	SSPN	ENSG00000123096.11			42412	-2.994	-0.0295	No
198	NUP93	ENSG00000102900.13			42500	-3.124	-0.0187	No
199	FPR1	ENSG00000171051.8			42753	-3.730	-0.0093	No
200	VAMP8	ENSG00000118640.11			42924	-4.365	0.0045	No

Fig 2: HALLMARK_INTERFERON_GAMMA_RESPONSE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_INTERFERON_GAMMA_RESPONSE: Random ES distribution   
Gene set null distribution of ES for HALLMARK_INTERFERON_GAMMA_RESPONSE