Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | HALLMARK_MYC_TARGETS_V1 |
| Enrichment Score (ES) | -0.5943999 |
| Normalized Enrichment Score (NES) | -2.3555849 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | AP3S1 | ENSG00000177879.16 | 1336 | 1.916 | -0.0210 | No | ||
| 2 | PRDX4 | ENSG00000123131.13 | 2016 | 1.623 | -0.0282 | No | ||
| 3 | RPL22 | ENSG00000116251.11 | 2661 | 1.423 | -0.0356 | No | ||
| 4 | PRPS2 | ENSG00000101911.12 | 3406 | 1.243 | -0.0463 | No | ||
| 5 | CDK4 | ENSG00000135446.17 | 4137 | 1.105 | -0.0575 | No | ||
| 6 | DUT | ENSG00000128951.14 | 4996 | 0.969 | -0.0723 | No | ||
| 7 | IFRD1 | ENSG00000006652.14 | 6482 | 0.790 | -0.1027 | No | ||
| 8 | RPS6 | ENSG00000137154.13 | 6666 | 0.771 | -0.1029 | No | ||
| 9 | YWHAQ | ENSG00000134308.14 | 7168 | 0.722 | -0.1108 | No | ||
| 10 | RPL34 | ENSG00000109475.16 | 7240 | 0.715 | -0.1086 | No | ||
| 11 | FBL | ENSG00000105202.9 | 7708 | 0.671 | -0.1159 | No | ||
| 12 | TFDP1 | ENSG00000198176.13 | 7858 | 0.659 | -0.1159 | No | ||
| 13 | RACK1 | ENSG00000204628.12 | 8353 | 0.615 | -0.1242 | No | ||
| 14 | TYMS | ENSG00000176890.16 | 8763 | 0.586 | -0.1306 | No | ||
| 15 | PCNA | ENSG00000132646.11 | 8869 | 0.578 | -0.1300 | No | ||
| 16 | RPL14 | ENSG00000188846.14 | 9661 | 0.525 | -0.1456 | No | ||
| 17 | RPS5 | ENSG00000083845.9 | 10273 | 0.493 | -0.1572 | No | ||
| 18 | CAD | ENSG00000084774.14 | 10953 | 0.448 | -0.1707 | No | ||
| 19 | RPS3 | ENSG00000149273.15 | 12363 | 0.372 | -0.2015 | No | ||
| 20 | PABPC4 | ENSG00000090621.14 | 12676 | 0.362 | -0.2069 | No | ||
| 21 | RPLP0 | ENSG00000089157.16 | 13023 | 0.353 | -0.2130 | No | ||
| 22 | HSPD1 | ENSG00000144381.17 | 13323 | 0.338 | -0.2182 | No | ||
| 23 | SNRPD2 | ENSG00000125743.10 | 13341 | 0.337 | -0.2168 | No | ||
| 24 | PPIA | ENSG00000196262.14 | 13437 | 0.331 | -0.2173 | No | ||
| 25 | PABPC1 | ENSG00000070756.16 | 14783 | 0.292 | -0.2471 | No | ||
| 26 | IMPDH2 | ENSG00000178035.12 | 15620 | 0.269 | -0.2651 | No | ||
| 27 | CLNS1A | ENSG00000074201.9 | 16063 | 0.245 | -0.2741 | No | ||
| 28 | EEF1B2 | ENSG00000114942.14 | 16066 | 0.245 | -0.2729 | No | ||
| 29 | PSMA2 | ENSG00000106588.11 | 16418 | 0.224 | -0.2799 | No | ||
| 30 | HNRNPA1 | ENSG00000135486.17 | 17283 | 0.184 | -0.2990 | No | ||
| 31 | LSM7 | ENSG00000130332.15 | 17386 | 0.179 | -0.3004 | No | ||
| 32 | XPOT | ENSG00000184575.12 | 17845 | 0.155 | -0.3103 | No | ||
| 33 | SRM | ENSG00000116649.10 | 17885 | 0.152 | -0.3104 | No | ||
| 34 | PWP1 | ENSG00000136045.12 | 18152 | 0.138 | -0.3159 | No | ||
| 35 | RPL18 | ENSG00000063177.13 | 18965 | 0.100 | -0.3342 | No | ||
| 36 | U2AF1 | ENSG00000160201.11 | 19374 | 0.079 | -0.3433 | No | ||
| 37 | HSPE1 | ENSG00000115541.11 | 19716 | 0.059 | -0.3510 | No | ||
| 38 | MRPL23 | ENSG00000214026.11 | 19983 | 0.048 | -0.3569 | No | ||
| 39 | UBA2 | ENSG00000126261.13 | 20030 | 0.047 | -0.3577 | No | ||
| 40 | SNRPG | ENSG00000143977.14 | 20606 | 0.017 | -0.3710 | No | ||
| 41 | MCM7 | ENSG00000166508.17 | 20623 | 0.016 | -0.3713 | No | ||
| 42 | NPM1 | ENSG00000181163.13 | 22984 | -0.111 | -0.4257 | No | ||
| 43 | USP1 | ENSG00000162607.13 | 23075 | -0.117 | -0.4272 | No | ||
| 44 | LDHA | ENSG00000134333.14 | 23158 | -0.122 | -0.4285 | No | ||
| 45 | UBE2L3 | ENSG00000185651.14 | 23515 | -0.141 | -0.4360 | No | ||
| 46 | DHX15 | ENSG00000109606.13 | 23647 | -0.149 | -0.4383 | No | ||
| 47 | SRPK1 | ENSG00000096063.16 | 23722 | -0.153 | -0.4392 | No | ||
| 48 | TXNL4A | ENSG00000141759.15 | 23982 | -0.170 | -0.4443 | No | ||
| 49 | SNRPA1 | ENSG00000131876.17 | 24006 | -0.172 | -0.4439 | No | ||
| 50 | RPS2 | ENSG00000140988.16 | 24024 | -0.173 | -0.4434 | No | ||
| 51 | ACP1 | ENSG00000143727.16 | 24087 | -0.176 | -0.4439 | No | ||
| 52 | LSM2 | ENSG00000204392.11 | 24687 | -0.211 | -0.4568 | No | ||
| 53 | EIF4H | ENSG00000106682.14 | 24697 | -0.211 | -0.4558 | No | ||
| 54 | BUB3 | ENSG00000154473.18 | 25548 | -0.230 | -0.4744 | No | ||
| 55 | PHB2 | ENSG00000215021.9 | 25695 | -0.240 | -0.4766 | No | ||
| 56 | CUL1 | ENSG00000055130.17 | 26496 | -0.266 | -0.4938 | No | ||
| 57 | HDGF | ENSG00000143321.19 | 27965 | -0.306 | -0.5264 | No | ||
| 58 | RPS10 | ENSG00000124614.16 | 28029 | -0.311 | -0.5262 | No | ||
| 59 | ORC2 | ENSG00000115942.9 | 28093 | -0.316 | -0.5260 | No | ||
| 60 | STARD7 | ENSG00000084090.13 | 28146 | -0.319 | -0.5255 | No | ||
| 61 | MCM6 | ENSG00000076003.5 | 28225 | -0.325 | -0.5256 | No | ||
| 62 | MRPL9 | ENSG00000143436.11 | 28288 | -0.329 | -0.5253 | No | ||
| 63 | PRDX3 | ENSG00000165672.7 | 28518 | -0.337 | -0.5288 | No | ||
| 64 | ERH | ENSG00000100632.11 | 28766 | -0.349 | -0.5327 | No | ||
| 65 | PSMB3 | ENSG00000277791.5 | 29269 | -0.361 | -0.5425 | No | ||
| 66 | MRPS18B | ENSG00000204568.12 | 29892 | -0.398 | -0.5549 | No | ||
| 67 | HPRT1 | ENSG00000165704.15 | 29958 | -0.404 | -0.5542 | No | ||
| 68 | H2AFZ | ENSG00000164032.12 | 30267 | -0.427 | -0.5592 | No | ||
| 69 | PSMA1 | ENSG00000129084.17 | 30662 | -0.448 | -0.5660 | No | ||
| 70 | TARDBP | ENSG00000120948.17 | 30835 | -0.456 | -0.5676 | No | ||
| 71 | HNRNPU | ENSG00000153187.20 | 31095 | -0.467 | -0.5711 | No | ||
| 72 | CNBP | ENSG00000169714.16 | 31260 | -0.475 | -0.5724 | No | ||
| 73 | EIF3D | ENSG00000100353.18 | 31314 | -0.479 | -0.5711 | No | ||
| 74 | PTGES3 | ENSG00000110958.16 | 31379 | -0.484 | -0.5700 | No | ||
| 75 | SF3A1 | ENSG00000099995.19 | 31632 | -0.496 | -0.5733 | No | ||
| 76 | MAD2L1 | ENSG00000164109.14 | 32397 | -0.539 | -0.5882 | No | ||
| 77 | PRPF31 | ENSG00000105618.14 | 32516 | -0.544 | -0.5881 | No | ||
| 78 | PCBP1 | ENSG00000169564.7 | 32549 | -0.547 | -0.5859 | No | ||
| 79 | RANBP1 | ENSG00000099901.17 | 32652 | -0.556 | -0.5853 | No | ||
| 80 | FAM120A | ENSG00000048828.17 | 32808 | -0.569 | -0.5859 | No | ||
| 81 | SLC25A3 | ENSG00000075415.12 | 32889 | -0.575 | -0.5847 | No | ||
| 82 | MCM5 | ENSG00000100297.16 | 32907 | -0.577 | -0.5821 | No | ||
| 83 | HNRNPA3 | ENSG00000170144.20 | 33147 | -0.594 | -0.5845 | No | ||
| 84 | NHP2 | ENSG00000145912.8 | 33172 | -0.596 | -0.5819 | No | ||
| 85 | HNRNPC | ENSG00000092199.17 | 33215 | -0.599 | -0.5797 | No | ||
| 86 | CBX3 | ENSG00000122565.19 | 33342 | -0.609 | -0.5794 | No | ||
| 87 | PPM1G | ENSG00000115241.11 | 33465 | -0.618 | -0.5789 | No | ||
| 88 | EIF2S2 | ENSG00000125977.7 | 33567 | -0.626 | -0.5780 | No | ||
| 89 | TRA2B | ENSG00000136527.18 | 33612 | -0.630 | -0.5756 | No | ||
| 90 | KPNB1 | ENSG00000108424.10 | 33836 | -0.648 | -0.5774 | No | ||
| 91 | EIF4G2 | ENSG00000110321.17 | 33928 | -0.656 | -0.5760 | No | ||
| 92 | EXOSC7 | ENSG00000075914.13 | 34509 | -0.703 | -0.5858 | No | ||
| 93 | SSBP1 | ENSG00000106028.11 | 34672 | -0.715 | -0.5858 | No | ||
| 94 | SNRPD1 | ENSG00000167088.11 | 35042 | -0.745 | -0.5904 | Yes | ||
| 95 | EIF4E | ENSG00000151247.12 | 35069 | -0.748 | -0.5871 | Yes | ||
| 96 | EPRS | ENSG00000136628.18 | 35243 | -0.763 | -0.5871 | Yes | ||
| 97 | MYC | ENSG00000136997.19 | 35251 | -0.763 | -0.5832 | Yes | ||
| 98 | CDC45 | ENSG00000093009.10 | 35359 | -0.774 | -0.5816 | Yes | ||
| 99 | CCNA2 | ENSG00000145386.10 | 35426 | -0.780 | -0.5790 | Yes | ||
| 100 | APEX1 | ENSG00000100823.12 | 35512 | -0.788 | -0.5768 | Yes | ||
| 101 | G3BP1 | ENSG00000145907.15 | 35567 | -0.794 | -0.5738 | Yes | ||
| 102 | SRSF7 | ENSG00000115875.19 | 35583 | -0.796 | -0.5699 | Yes | ||
| 103 | EIF3B | ENSG00000106263.18 | 35592 | -0.797 | -0.5659 | Yes | ||
| 104 | HNRNPD | ENSG00000138668.19 | 35597 | -0.797 | -0.5617 | Yes | ||
| 105 | SYNCRIP | ENSG00000135316.18 | 35659 | -0.804 | -0.5589 | Yes | ||
| 106 | PSMA7 | ENSG00000101182.15 | 35709 | -0.810 | -0.5557 | Yes | ||
| 107 | SRSF3 | ENSG00000112081.17 | 35803 | -0.818 | -0.5536 | Yes | ||
| 108 | PSMB2 | ENSG00000126067.12 | 35837 | -0.822 | -0.5500 | Yes | ||
| 109 | CDC20 | ENSG00000117399.14 | 35877 | -0.828 | -0.5465 | Yes | ||
| 110 | MCM4 | ENSG00000104738.18 | 35969 | -0.840 | -0.5441 | Yes | ||
| 111 | HDDC2 | ENSG00000111906.18 | 35991 | -0.843 | -0.5402 | Yes | ||
| 112 | NCBP2 | ENSG00000114503.11 | 36040 | -0.848 | -0.5368 | Yes | ||
| 113 | SET | ENSG00000119335.16 | 36253 | -0.872 | -0.5371 | Yes | ||
| 114 | IARS | ENSG00000196305.17 | 36258 | -0.873 | -0.5325 | Yes | ||
| 115 | GNL3 | ENSG00000163938.17 | 36410 | -0.890 | -0.5313 | Yes | ||
| 116 | UBE2E1 | ENSG00000170142.12 | 36422 | -0.891 | -0.5269 | Yes | ||
| 117 | RRM1 | ENSG00000167325.15 | 36485 | -0.899 | -0.5235 | Yes | ||
| 118 | SNRPA | ENSG00000077312.9 | 36547 | -0.906 | -0.5202 | Yes | ||
| 119 | COPS5 | ENSG00000121022.14 | 36709 | -0.931 | -0.5190 | Yes | ||
| 120 | XRCC6 | ENSG00000196419.12 | 36832 | -0.946 | -0.5168 | Yes | ||
| 121 | MCM2 | ENSG00000073111.14 | 36965 | -0.962 | -0.5148 | Yes | ||
| 122 | CDK2 | ENSG00000123374.11 | 37047 | -0.974 | -0.5115 | Yes | ||
| 123 | GLO1 | ENSG00000124767.7 | 37048 | -0.974 | -0.5063 | Yes | ||
| 124 | EIF4A1 | ENSG00000161960.15 | 37239 | -0.997 | -0.5054 | Yes | ||
| 125 | SF3B3 | ENSG00000189091.13 | 37299 | -1.007 | -0.5015 | Yes | ||
| 126 | RSL1D1 | ENSG00000171490.13 | 37311 | -1.008 | -0.4964 | Yes | ||
| 127 | SRSF1 | ENSG00000136450.13 | 37367 | -1.015 | -0.4923 | Yes | ||
| 128 | DEK | ENSG00000124795.17 | 37596 | -1.050 | -0.4920 | Yes | ||
| 129 | SRSF2 | ENSG00000161547.16 | 37659 | -1.061 | -0.4878 | Yes | ||
| 130 | XPO1 | ENSG00000082898.17 | 37727 | -1.072 | -0.4837 | Yes | ||
| 131 | TRIM28 | ENSG00000130726.12 | 37782 | -1.081 | -0.4792 | Yes | ||
| 132 | RFC4 | ENSG00000163918.10 | 37809 | -1.085 | -0.4741 | Yes | ||
| 133 | HNRNPA2B1 | ENSG00000122566.21 | 38081 | -1.132 | -0.4744 | Yes | ||
| 134 | VBP1 | ENSG00000155959.12 | 38118 | -1.138 | -0.4692 | Yes | ||
| 135 | PSMA4 | ENSG00000041357.16 | 38333 | -1.177 | -0.4679 | Yes | ||
| 136 | GOT2 | ENSG00000125166.13 | 38450 | -1.197 | -0.4642 | Yes | ||
| 137 | SNRPD3 | ENSG00000100028.12 | 38472 | -1.201 | -0.4584 | Yes | ||
| 138 | C1QBP | ENSG00000108561.8 | 38615 | -1.226 | -0.4552 | Yes | ||
| 139 | RNPS1 | ENSG00000205937.12 | 38619 | -1.227 | -0.4487 | Yes | ||
| 140 | CYC1 | ENSG00000179091.5 | 38710 | -1.245 | -0.4442 | Yes | ||
| 141 | PSMD7 | ENSG00000103035.11 | 38868 | -1.282 | -0.4411 | Yes | ||
| 142 | GSPT1 | ENSG00000103342.13 | 38876 | -1.284 | -0.4344 | Yes | ||
| 143 | ETF1 | ENSG00000120705.13 | 39011 | -1.312 | -0.4306 | Yes | ||
| 144 | SERBP1 | ENSG00000142864.14 | 39100 | -1.331 | -0.4255 | Yes | ||
| 145 | DDX18 | ENSG00000088205.13 | 39130 | -1.337 | -0.4191 | Yes | ||
| 146 | NAP1L1 | ENSG00000187109.14 | 39234 | -1.361 | -0.4143 | Yes | ||
| 147 | HNRNPR | ENSG00000125944.20 | 39305 | -1.378 | -0.4086 | Yes | ||
| 148 | SNRPB2 | ENSG00000125870.11 | 39337 | -1.385 | -0.4020 | Yes | ||
| 149 | EIF1AX | ENSG00000173674.11 | 39371 | -1.391 | -0.3954 | Yes | ||
| 150 | CCT4 | ENSG00000115484.15 | 39465 | -1.414 | -0.3900 | Yes | ||
| 151 | NOP16 | ENSG00000048162.20 | 39472 | -1.417 | -0.3827 | Yes | ||
| 152 | RRP9 | ENSG00000114767.7 | 39550 | -1.431 | -0.3769 | Yes | ||
| 153 | PSMA6 | ENSG00000100902.11 | 39610 | -1.444 | -0.3706 | Yes | ||
| 154 | POLE3 | ENSG00000148229.13 | 39649 | -1.454 | -0.3637 | Yes | ||
| 155 | PSMD3 | ENSG00000108344.15 | 39660 | -1.456 | -0.3562 | Yes | ||
| 156 | VDAC1 | ENSG00000213585.11 | 39742 | -1.476 | -0.3503 | Yes | ||
| 157 | TCP1 | ENSG00000120438.12 | 39803 | -1.494 | -0.3438 | Yes | ||
| 158 | SMARCC1 | ENSG00000173473.11 | 39851 | -1.506 | -0.3369 | Yes | ||
| 159 | SSB | ENSG00000138385.16 | 39877 | -1.516 | -0.3294 | Yes | ||
| 160 | RUVBL2 | ENSG00000183207.14 | 39894 | -1.521 | -0.3217 | Yes | ||
| 161 | VDAC3 | ENSG00000078668.14 | 39954 | -1.536 | -0.3149 | Yes | ||
| 162 | RAN | ENSG00000132341.12 | 39982 | -1.544 | -0.3073 | Yes | ||
| 163 | ILF2 | ENSG00000143621.17 | 40052 | -1.560 | -0.3007 | Yes | ||
| 164 | PHB | ENSG00000167085.11 | 40143 | -1.585 | -0.2944 | Yes | ||
| 165 | ABCE1 | ENSG00000164163.11 | 40196 | -1.598 | -0.2871 | Yes | ||
| 166 | RAD23B | ENSG00000119318.13 | 40214 | -1.603 | -0.2790 | Yes | ||
| 167 | POLD2 | ENSG00000106628.10 | 40288 | -1.623 | -0.2721 | Yes | ||
| 168 | PSMD8 | ENSG00000099341.11 | 40314 | -1.631 | -0.2640 | Yes | ||
| 169 | PSMC4 | ENSG00000013275.8 | 40405 | -1.659 | -0.2573 | Yes | ||
| 170 | CCT3 | ENSG00000163468.15 | 40427 | -1.663 | -0.2489 | Yes | ||
| 171 | KARS | ENSG00000065427.14 | 40450 | -1.672 | -0.2406 | Yes | ||
| 172 | NOP56 | ENSG00000101361.17 | 40492 | -1.685 | -0.2326 | Yes | ||
| 173 | TOMM70 | ENSG00000154174.8 | 40512 | -1.693 | -0.2240 | Yes | ||
| 174 | TUFM | ENSG00000178952.11 | 40543 | -1.700 | -0.2157 | Yes | ||
| 175 | CANX | ENSG00000127022.15 | 40544 | -1.700 | -0.2067 | Yes | ||
| 176 | CCT5 | ENSG00000150753.12 | 40604 | -1.719 | -0.1989 | Yes | ||
| 177 | EIF2S1 | ENSG00000134001.13 | 40613 | -1.722 | -0.1900 | Yes | ||
| 178 | HDAC2 | ENSG00000196591.12 | 40692 | -1.746 | -0.1825 | Yes | ||
| 179 | PSMD14 | ENSG00000115233.12 | 40751 | -1.767 | -0.1745 | Yes | ||
| 180 | COX5A | ENSG00000178741.12 | 40756 | -1.769 | -0.1652 | Yes | ||
| 181 | PSMC6 | ENSG00000100519.12 | 40791 | -1.783 | -0.1565 | Yes | ||
| 182 | CSTF2 | ENSG00000101811.13 | 40885 | -1.816 | -0.1491 | Yes | ||
| 183 | HSP90AB1 | ENSG00000096384.20 | 40961 | -1.848 | -0.1410 | Yes | ||
| 184 | NME1 | ENSG00000239672.7 | 41010 | -1.873 | -0.1322 | Yes | ||
| 185 | YWHAE | ENSG00000108953.17 | 41073 | -1.896 | -0.1236 | Yes | ||
| 186 | PGK1 | ENSG00000102144.15 | 41108 | -1.912 | -0.1142 | Yes | ||
| 187 | PA2G4 | ENSG00000170515.14 | 41191 | -1.955 | -0.1057 | Yes | ||
| 188 | NOLC1 | ENSG00000166197.16 | 41247 | -1.977 | -0.0965 | Yes | ||
| 189 | KPNA2 | ENSG00000182481.9 | 41262 | -1.982 | -0.0863 | Yes | ||
| 190 | PSMD1 | ENSG00000173692.13 | 41284 | -1.994 | -0.0762 | Yes | ||
| 191 | CTPS1 | ENSG00000171793.16 | 41388 | -2.056 | -0.0677 | Yes | ||
| 192 | NCBP1 | ENSG00000136937.13 | 41449 | -2.100 | -0.0580 | Yes | ||
| 193 | EIF3J | ENSG00000104131.13 | 41556 | -2.168 | -0.0489 | Yes | ||
| 194 | CCT7 | ENSG00000135624.16 | 41607 | -2.199 | -0.0384 | Yes | ||
| 195 | NDUFAB1 | ENSG00000004779.10 | 41690 | -2.242 | -0.0284 | Yes | ||
| 196 | AIMP2 | ENSG00000106305.10 | 41843 | -2.363 | -0.0194 | Yes | ||
| 197 | DDX21 | ENSG00000165732.13 | 42089 | -2.560 | -0.0116 | Yes | ||
| 198 | CCT2 | ENSG00000166226.13 | 42456 | -3.068 | -0.0038 | Yes | ||
| 199 | ODC1 | ENSG00000115758.13 | 42710 | -3.622 | 0.0095 | Yes |
