Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | HALLMARK_NOTCH_SIGNALING |
| Enrichment Score (ES) | -0.38462952 |
| Normalized Enrichment Score (NES) | -1.1327797 |
| Nominal p-value | 0.318542 |
| FDR q-value | 0.25831503 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ARRB1 | ENSG00000137486.17 | 1444 | 1.868 | 0.0193 | No | ||
| 2 | FZD7 | ENSG00000155760.2 | 1491 | 1.848 | 0.0704 | No | ||
| 3 | MAML2 | ENSG00000184384.14 | 1606 | 1.797 | 0.1185 | No | ||
| 4 | TCF7L2 | ENSG00000148737.17 | 1732 | 1.743 | 0.1649 | No | ||
| 5 | APH1A | ENSG00000117362.13 | 3241 | 1.278 | 0.1660 | No | ||
| 6 | CCND1 | ENSG00000110092.3 | 4717 | 1.011 | 0.1603 | No | ||
| 7 | WNT2 | ENSG00000105989.10 | 4853 | 0.989 | 0.1851 | No | ||
| 8 | ST3GAL6 | ENSG00000064225.12 | 6793 | 0.758 | 0.1616 | No | ||
| 9 | PPARD | ENSG00000112033.14 | 7445 | 0.695 | 0.1661 | No | ||
| 10 | FZD1 | ENSG00000157240.4 | 7851 | 0.659 | 0.1753 | No | ||
| 11 | PRKCA | ENSG00000154229.12 | 8575 | 0.601 | 0.1755 | No | ||
| 12 | KAT2A | ENSG00000108773.11 | 13577 | 0.322 | 0.0686 | No | ||
| 13 | WNT5A | ENSG00000114251.14 | 17212 | 0.187 | -0.0105 | No | ||
| 14 | DTX1 | ENSG00000135144.7 | 19428 | 0.075 | -0.0598 | No | ||
| 15 | DTX2 | ENSG00000091073.19 | 20483 | 0.024 | -0.0836 | No | ||
| 16 | PSEN2 | ENSG00000143801.17 | 23491 | -0.140 | -0.1494 | No | ||
| 17 | NOTCH2 | ENSG00000134250.20 | 23887 | -0.164 | -0.1539 | No | ||
| 18 | PSENEN | ENSG00000205155.8 | 24593 | -0.204 | -0.1645 | No | ||
| 19 | CUL1 | ENSG00000055130.17 | 26496 | -0.266 | -0.2012 | No | ||
| 20 | NOTCH1 | ENSG00000148400.12 | 27170 | -0.285 | -0.2087 | No | ||
| 21 | SAP30 | ENSG00000164105.4 | 28782 | -0.351 | -0.2362 | No | ||
| 22 | RBX1 | ENSG00000100387.9 | 33259 | -0.602 | -0.3231 | No | ||
| 23 | JAG1 | ENSG00000101384.12 | 35655 | -0.804 | -0.3559 | No | ||
| 24 | SKP1 | ENSG00000113558.18 | 36892 | -0.952 | -0.3577 | Yes | ||
| 25 | FBXW11 | ENSG00000072803.17 | 37218 | -0.994 | -0.3372 | Yes | ||
| 26 | LFNG | ENSG00000106003.13 | 37364 | -1.015 | -0.3119 | Yes | ||
| 27 | HES1 | ENSG00000114315.4 | 39235 | -1.362 | -0.3168 | Yes | ||
| 28 | DTX4 | ENSG00000110042.8 | 41459 | -2.106 | -0.3089 | Yes | ||
| 29 | NOTCH3 | ENSG00000074181.9 | 42061 | -2.537 | -0.2512 | Yes | ||
| 30 | FZD5 | ENSG00000163251.4 | 42233 | -2.747 | -0.1775 | Yes | ||
| 31 | DLL1 | ENSG00000198719.9 | 42490 | -3.113 | -0.0955 | Yes | ||
| 32 | HEYL | ENSG00000163909.8 | 42800 | -3.896 | 0.0074 | Yes |
