Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.5024948 |
| Normalized Enrichment Score (NES) | -2.0253272 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GPX4 | ENSG00000167468.17 | 652 | 2.411 | -0.0026 | No | ||
| 2 | IDH1 | ENSG00000138413.13 | 771 | 2.290 | 0.0066 | No | ||
| 3 | CPT1A | ENSG00000110090.13 | 776 | 2.287 | 0.0185 | No | ||
| 4 | OAT | ENSG00000065154.11 | 1219 | 1.982 | 0.0186 | No | ||
| 5 | ISCU | ENSG00000136003.15 | 1254 | 1.961 | 0.0280 | No | ||
| 6 | NQO2 | ENSG00000124588.20 | 1876 | 1.678 | 0.0224 | No | ||
| 7 | MGST3 | ENSG00000143198.13 | 1903 | 1.667 | 0.0305 | No | ||
| 8 | TCIRG1 | ENSG00000110719.10 | 1974 | 1.641 | 0.0374 | No | ||
| 9 | CYB5A | ENSG00000166347.19 | 2498 | 1.475 | 0.0329 | No | ||
| 10 | MRPL34 | ENSG00000130312.6 | 3300 | 1.269 | 0.0209 | No | ||
| 11 | BAX | ENSG00000087088.20 | 3520 | 1.222 | 0.0222 | No | ||
| 12 | SDHD | ENSG00000204370.12 | 3584 | 1.209 | 0.0271 | No | ||
| 13 | PDP1 | ENSG00000164951.16 | 3884 | 1.148 | 0.0261 | No | ||
| 14 | BDH2 | ENSG00000164039.15 | 3929 | 1.140 | 0.0310 | No | ||
| 15 | MAOB | ENSG00000069535.14 | 4865 | 0.988 | 0.0144 | No | ||
| 16 | MRPL11 | ENSG00000174547.13 | 5195 | 0.940 | 0.0117 | No | ||
| 17 | ATP6V1F | ENSG00000128524.5 | 5271 | 0.931 | 0.0148 | No | ||
| 18 | FDX1 | ENSG00000137714.3 | 5937 | 0.849 | 0.0038 | No | ||
| 19 | ALDH6A1 | ENSG00000119711.13 | 6141 | 0.824 | 0.0033 | No | ||
| 20 | DLST | ENSG00000119689.15 | 6991 | 0.739 | -0.0126 | No | ||
| 21 | CYB5R3 | ENSG00000100243.21 | 7054 | 0.733 | -0.0102 | No | ||
| 22 | ACAT1 | ENSG00000075239.14 | 7197 | 0.720 | -0.0097 | No | ||
| 23 | NDUFA7 | ENSG00000267855.6 | 7349 | 0.706 | -0.0096 | No | ||
| 24 | GLUD1 | ENSG00000148672.9 | 7374 | 0.703 | -0.0064 | No | ||
| 25 | MTRR | ENSG00000124275.15 | 7381 | 0.703 | -0.0029 | No | ||
| 26 | PHYH | ENSG00000107537.14 | 7726 | 0.670 | -0.0074 | No | ||
| 27 | ATP6V1C1 | ENSG00000155097.12 | 7976 | 0.649 | -0.0098 | No | ||
| 28 | UQCRB | ENSG00000156467.9 | 10109 | 0.503 | -0.0569 | No | ||
| 29 | ATP6V0C | ENSG00000185883.12 | 10646 | 0.469 | -0.0669 | No | ||
| 30 | ACADSB | ENSG00000196177.12 | 10659 | 0.468 | -0.0647 | No | ||
| 31 | ACAA1 | ENSG00000060971.18 | 10861 | 0.454 | -0.0671 | No | ||
| 32 | RETSAT | ENSG00000042445.14 | 11072 | 0.439 | -0.0696 | No | ||
| 33 | ATP5MG | ENSG00000167283.8 | 11209 | 0.432 | -0.0706 | No | ||
| 34 | ATP6V0E1 | ENSG00000113732.9 | 11789 | 0.397 | -0.0820 | No | ||
| 35 | PDK4 | ENSG00000004799.8 | 12237 | 0.375 | -0.0904 | No | ||
| 36 | ATP6V1G1 | ENSG00000136888.7 | 12733 | 0.359 | -0.1001 | No | ||
| 37 | SLC25A12 | ENSG00000115840.14 | 15473 | 0.276 | -0.1624 | No | ||
| 38 | NDUFS4 | ENSG00000164258.12 | 15726 | 0.264 | -0.1669 | No | ||
| 39 | COX4I1 | ENSG00000131143.9 | 15881 | 0.255 | -0.1692 | No | ||
| 40 | TIMM9 | ENSG00000100575.14 | 16125 | 0.241 | -0.1736 | No | ||
| 41 | ECI1 | ENSG00000167969.13 | 17162 | 0.189 | -0.1967 | No | ||
| 42 | IDH3G | ENSG00000067829.19 | 17636 | 0.167 | -0.2069 | No | ||
| 43 | OXA1L | ENSG00000155463.14 | 18249 | 0.134 | -0.2204 | No | ||
| 44 | ATP5F1E | ENSG00000124172.10 | 19090 | 0.095 | -0.2395 | No | ||
| 45 | SURF1 | ENSG00000148290.10 | 19112 | 0.094 | -0.2395 | No | ||
| 46 | ACADVL | ENSG00000072778.20 | 19159 | 0.091 | -0.2401 | No | ||
| 47 | FXN | ENSG00000165060.14 | 19429 | 0.075 | -0.2460 | No | ||
| 48 | ATP5F1D | ENSG00000099624.8 | 19774 | 0.057 | -0.2537 | No | ||
| 49 | UQCRH | ENSG00000173660.12 | 21041 | -0.006 | -0.2832 | No | ||
| 50 | NDUFA2 | ENSG00000131495.8 | 21146 | -0.013 | -0.2855 | No | ||
| 51 | HADHA | ENSG00000084754.12 | 21253 | -0.019 | -0.2879 | No | ||
| 52 | COX7A2L | ENSG00000115944.15 | 21364 | -0.024 | -0.2903 | No | ||
| 53 | UQCR11 | ENSG00000127540.12 | 21789 | -0.046 | -0.3000 | No | ||
| 54 | MRPS22 | ENSG00000175110.11 | 21790 | -0.046 | -0.2997 | No | ||
| 55 | NDUFB1 | ENSG00000183648.10 | 22559 | -0.088 | -0.3171 | No | ||
| 56 | CASP7 | ENSG00000165806.20 | 23029 | -0.113 | -0.3275 | No | ||
| 57 | LDHA | ENSG00000134333.14 | 23158 | -0.122 | -0.3298 | No | ||
| 58 | COX7C | ENSG00000127184.13 | 23199 | -0.124 | -0.3301 | No | ||
| 59 | HTRA2 | ENSG00000115317.11 | 23340 | -0.132 | -0.3327 | No | ||
| 60 | MRPS15 | ENSG00000116898.12 | 23557 | -0.144 | -0.3370 | No | ||
| 61 | MTRF1 | ENSG00000120662.16 | 23754 | -0.153 | -0.3407 | No | ||
| 62 | NDUFS7 | ENSG00000115286.20 | 23943 | -0.168 | -0.3442 | No | ||
| 63 | NDUFB8 | ENSG00000166136.16 | 23962 | -0.169 | -0.3438 | No | ||
| 64 | SDHA | ENSG00000073578.17 | 24192 | -0.182 | -0.3481 | No | ||
| 65 | NDUFC2 | ENSG00000151366.13 | 24279 | -0.187 | -0.3492 | No | ||
| 66 | ETFB | ENSG00000105379.9 | 24745 | -0.215 | -0.3589 | No | ||
| 67 | RHOT1 | ENSG00000126858.18 | 24789 | -0.218 | -0.3587 | No | ||
| 68 | COX6B1 | ENSG00000126267.11 | 25561 | -0.231 | -0.3755 | No | ||
| 69 | RHOT2 | ENSG00000140983.14 | 25586 | -0.232 | -0.3748 | No | ||
| 70 | PHB2 | ENSG00000215021.9 | 25695 | -0.240 | -0.3761 | No | ||
| 71 | NDUFC1 | ENSG00000109390.12 | 26484 | -0.265 | -0.3931 | No | ||
| 72 | MRPS30 | ENSG00000112996.11 | 26533 | -0.269 | -0.3928 | No | ||
| 73 | NDUFA5 | ENSG00000128609.15 | 27038 | -0.276 | -0.4031 | No | ||
| 74 | POLR2F | ENSG00000100142.15 | 27064 | -0.278 | -0.4022 | No | ||
| 75 | ATP5PD | ENSG00000167863.12 | 28443 | -0.334 | -0.4326 | No | ||
| 76 | PRDX3 | ENSG00000165672.7 | 28518 | -0.337 | -0.4325 | No | ||
| 77 | SUCLG1 | ENSG00000163541.12 | 28761 | -0.349 | -0.4363 | No | ||
| 78 | COX6A1 | ENSG00000111775.3 | 29637 | -0.384 | -0.4547 | No | ||
| 79 | NDUFS3 | ENSG00000213619.10 | 30108 | -0.414 | -0.4635 | No | ||
| 80 | NDUFS8 | ENSG00000110717.13 | 30259 | -0.426 | -0.4648 | No | ||
| 81 | NDUFA6 | ENSG00000184983.11 | 30283 | -0.428 | -0.4631 | No | ||
| 82 | SDHC | ENSG00000143252.14 | 30372 | -0.429 | -0.4629 | No | ||
| 83 | ISCA1 | ENSG00000135070.15 | 30563 | -0.438 | -0.4650 | No | ||
| 84 | HADHB | ENSG00000138029.14 | 30755 | -0.451 | -0.4671 | No | ||
| 85 | NDUFB7 | ENSG00000099795.7 | 30995 | -0.459 | -0.4703 | No | ||
| 86 | ATP5PO | ENSG00000241837.7 | 31091 | -0.467 | -0.4701 | No | ||
| 87 | NDUFV1 | ENSG00000167792.13 | 31274 | -0.476 | -0.4718 | No | ||
| 88 | NDUFB4 | ENSG00000065518.8 | 31830 | -0.503 | -0.4821 | No | ||
| 89 | ETFDH | ENSG00000171503.12 | 32005 | -0.514 | -0.4835 | No | ||
| 90 | IDH3B | ENSG00000101365.21 | 32024 | -0.515 | -0.4812 | No | ||
| 91 | NDUFA1 | ENSG00000125356.7 | 32133 | -0.521 | -0.4810 | No | ||
| 92 | NDUFB5 | ENSG00000136521.13 | 32252 | -0.531 | -0.4810 | No | ||
| 93 | ATP6AP1 | ENSG00000071553.17 | 32612 | -0.553 | -0.4864 | No | ||
| 94 | MPC1 | ENSG00000060762.19 | 32835 | -0.571 | -0.4886 | No | ||
| 95 | POR | ENSG00000127948.16 | 32862 | -0.573 | -0.4862 | No | ||
| 96 | SLC25A3 | ENSG00000075415.12 | 32889 | -0.575 | -0.4838 | No | ||
| 97 | ATP5F1A | ENSG00000152234.16 | 33057 | -0.587 | -0.4846 | No | ||
| 98 | SDHB | ENSG00000117118.9 | 33081 | -0.589 | -0.4821 | No | ||
| 99 | ATP6V1H | ENSG00000047249.18 | 33094 | -0.590 | -0.4793 | No | ||
| 100 | ECH1 | ENSG00000104823.9 | 33133 | -0.593 | -0.4771 | No | ||
| 101 | NDUFV2 | ENSG00000178127.13 | 33641 | -0.633 | -0.4856 | No | ||
| 102 | NDUFB2 | ENSG00000090266.13 | 33932 | -0.656 | -0.4889 | No | ||
| 103 | COX5B | ENSG00000135940.7 | 33952 | -0.658 | -0.4859 | No | ||
| 104 | MDH1 | ENSG00000014641.19 | 34029 | -0.662 | -0.4842 | No | ||
| 105 | FH | ENSG00000091483.6 | 34076 | -0.665 | -0.4818 | No | ||
| 106 | GPI | ENSG00000105220.17 | 34273 | -0.681 | -0.4828 | No | ||
| 107 | COX8A | ENSG00000176340.4 | 34436 | -0.697 | -0.4829 | No | ||
| 108 | NDUFA3 | ENSG00000170906.16 | 35193 | -0.759 | -0.4966 | No | ||
| 109 | ATP5MC3 | ENSG00000154518.9 | 35448 | -0.783 | -0.4984 | Yes | ||
| 110 | MFN2 | ENSG00000116688.16 | 35578 | -0.795 | -0.4972 | Yes | ||
| 111 | COX15 | ENSG00000014919.12 | 35759 | -0.814 | -0.4972 | Yes | ||
| 112 | ATP5MC2 | ENSG00000135390.20 | 35892 | -0.830 | -0.4959 | Yes | ||
| 113 | MTX2 | ENSG00000128654.14 | 36031 | -0.847 | -0.4947 | Yes | ||
| 114 | SUPV3L1 | ENSG00000156502.14 | 36144 | -0.861 | -0.4928 | Yes | ||
| 115 | LDHB | ENSG00000111716.13 | 36169 | -0.865 | -0.4888 | Yes | ||
| 116 | ATP5ME | ENSG00000169020.10 | 36282 | -0.876 | -0.4869 | Yes | ||
| 117 | MRPL35 | ENSG00000132313.15 | 36377 | -0.885 | -0.4844 | Yes | ||
| 118 | LRPPRC | ENSG00000138095.19 | 36597 | -0.914 | -0.4848 | Yes | ||
| 119 | ATP5PB | ENSG00000116459.11 | 36670 | -0.924 | -0.4816 | Yes | ||
| 120 | ATP6V1E1 | ENSG00000131100.13 | 36765 | -0.936 | -0.4789 | Yes | ||
| 121 | MRPS12 | ENSG00000128626.11 | 36940 | -0.958 | -0.4779 | Yes | ||
| 122 | UQCRFS1 | ENSG00000169021.6 | 37078 | -0.978 | -0.4760 | Yes | ||
| 123 | TOMM22 | ENSG00000100216.6 | 37119 | -0.982 | -0.4718 | Yes | ||
| 124 | PDHX | ENSG00000110435.12 | 37146 | -0.986 | -0.4673 | Yes | ||
| 125 | NNT | ENSG00000112992.18 | 37192 | -0.991 | -0.4631 | Yes | ||
| 126 | DLAT | ENSG00000150768.15 | 37363 | -1.015 | -0.4618 | Yes | ||
| 127 | SLC25A11 | ENSG00000108528.14 | 37422 | -1.023 | -0.4578 | Yes | ||
| 128 | TIMM17A | ENSG00000134375.11 | 37654 | -1.060 | -0.4576 | Yes | ||
| 129 | NDUFS6 | ENSG00000145494.11 | 37676 | -1.062 | -0.4525 | Yes | ||
| 130 | SLC25A5 | ENSG00000005022.6 | 37760 | -1.078 | -0.4488 | Yes | ||
| 131 | ALAS1 | ENSG00000023330.15 | 37768 | -1.078 | -0.4434 | Yes | ||
| 132 | MRPL15 | ENSG00000137547.9 | 37824 | -1.087 | -0.4390 | Yes | ||
| 133 | UQCR10 | ENSG00000184076.13 | 37826 | -1.087 | -0.4333 | Yes | ||
| 134 | TIMM10 | ENSG00000134809.9 | 37894 | -1.100 | -0.4291 | Yes | ||
| 135 | ATP5PF | ENSG00000154723.12 | 37895 | -1.100 | -0.4233 | Yes | ||
| 136 | COX7B | ENSG00000131174.7 | 37903 | -1.101 | -0.4178 | Yes | ||
| 137 | PMPCA | ENSG00000165688.12 | 37905 | -1.101 | -0.4120 | Yes | ||
| 138 | NDUFA9 | ENSG00000139180.11 | 38015 | -1.119 | -0.4087 | Yes | ||
| 139 | TIMM50 | ENSG00000105197.11 | 38083 | -1.132 | -0.4043 | Yes | ||
| 140 | UQCRQ | ENSG00000164405.11 | 38111 | -1.136 | -0.3990 | Yes | ||
| 141 | AIFM1 | ENSG00000156709.14 | 38213 | -1.156 | -0.3953 | Yes | ||
| 142 | AFG3L2 | ENSG00000141385.9 | 38241 | -1.161 | -0.3899 | Yes | ||
| 143 | ABCB7 | ENSG00000131269.19 | 38271 | -1.166 | -0.3845 | Yes | ||
| 144 | NDUFB6 | ENSG00000165264.11 | 38305 | -1.173 | -0.3791 | Yes | ||
| 145 | NDUFA8 | ENSG00000119421.7 | 38322 | -1.176 | -0.3733 | Yes | ||
| 146 | ATP5F1C | ENSG00000165629.20 | 38343 | -1.178 | -0.3676 | Yes | ||
| 147 | HSPA9 | ENSG00000113013.15 | 38400 | -1.187 | -0.3627 | Yes | ||
| 148 | GOT2 | ENSG00000125166.13 | 38450 | -1.197 | -0.3576 | Yes | ||
| 149 | MRPS11 | ENSG00000181991.16 | 38580 | -1.220 | -0.3542 | Yes | ||
| 150 | COX10 | ENSG00000006695.12 | 38672 | -1.238 | -0.3499 | Yes | ||
| 151 | CYC1 | ENSG00000179091.5 | 38710 | -1.245 | -0.3442 | Yes | ||
| 152 | ATP5MF | ENSG00000241468.7 | 38712 | -1.245 | -0.3377 | Yes | ||
| 153 | OPA1 | ENSG00000198836.10 | 38737 | -1.251 | -0.3317 | Yes | ||
| 154 | BCKDHA | ENSG00000248098.12 | 38800 | -1.267 | -0.3266 | Yes | ||
| 155 | UQCRC1 | ENSG00000010256.11 | 38824 | -1.273 | -0.3204 | Yes | ||
| 156 | ACO2 | ENSG00000100412.16 | 38900 | -1.290 | -0.3154 | Yes | ||
| 157 | CS | ENSG00000062485.19 | 39089 | -1.328 | -0.3129 | Yes | ||
| 158 | SLC25A20 | ENSG00000178537.10 | 39138 | -1.338 | -0.3070 | Yes | ||
| 159 | MDH2 | ENSG00000146701.12 | 39149 | -1.341 | -0.3002 | Yes | ||
| 160 | ACADM | ENSG00000117054.13 | 39201 | -1.353 | -0.2943 | Yes | ||
| 161 | DECR1 | ENSG00000104325.7 | 39242 | -1.363 | -0.2881 | Yes | ||
| 162 | HCCS | ENSG00000004961.15 | 39422 | -1.404 | -0.2850 | Yes | ||
| 163 | SUCLA2 | ENSG00000136143.16 | 39428 | -1.405 | -0.2777 | Yes | ||
| 164 | ECHS1 | ENSG00000127884.5 | 39473 | -1.417 | -0.2713 | Yes | ||
| 165 | DLD | ENSG00000091140.14 | 39495 | -1.421 | -0.2644 | Yes | ||
| 166 | COX6C | ENSG00000164919.11 | 39588 | -1.439 | -0.2590 | Yes | ||
| 167 | ATP6V0B | ENSG00000117410.14 | 39615 | -1.446 | -0.2520 | Yes | ||
| 168 | TIMM13 | ENSG00000099800.8 | 39661 | -1.456 | -0.2455 | Yes | ||
| 169 | NDUFA4 | ENSG00000189043.10 | 39683 | -1.463 | -0.2383 | Yes | ||
| 170 | VDAC1 | ENSG00000213585.11 | 39742 | -1.476 | -0.2319 | Yes | ||
| 171 | IMMT | ENSG00000132305.20 | 39920 | -1.527 | -0.2281 | Yes | ||
| 172 | IDH3A | ENSG00000166411.14 | 39940 | -1.532 | -0.2205 | Yes | ||
| 173 | VDAC3 | ENSG00000078668.14 | 39954 | -1.536 | -0.2128 | Yes | ||
| 174 | NDUFB3 | ENSG00000119013.9 | 40121 | -1.579 | -0.2084 | Yes | ||
| 175 | VDAC2 | ENSG00000165637.13 | 40139 | -1.584 | -0.2005 | Yes | ||
| 176 | ATP5MC1 | ENSG00000159199.14 | 40212 | -1.603 | -0.1938 | Yes | ||
| 177 | ETFA | ENSG00000140374.16 | 40279 | -1.619 | -0.1869 | Yes | ||
| 178 | ATP5F1B | ENSG00000110955.9 | 40290 | -1.624 | -0.1786 | Yes | ||
| 179 | COX7A2 | ENSG00000112695.11 | 40291 | -1.624 | -0.1701 | Yes | ||
| 180 | NDUFS1 | ENSG00000023228.14 | 40350 | -1.642 | -0.1629 | Yes | ||
| 181 | GRPEL1 | ENSG00000109519.13 | 40485 | -1.684 | -0.1572 | Yes | ||
| 182 | PDHB | ENSG00000168291.13 | 40487 | -1.684 | -0.1484 | Yes | ||
| 183 | TOMM70 | ENSG00000154174.8 | 40512 | -1.693 | -0.1401 | Yes | ||
| 184 | ATP6V1D | ENSG00000100554.12 | 40671 | -1.741 | -0.1347 | Yes | ||
| 185 | COX5A | ENSG00000178741.12 | 40756 | -1.769 | -0.1274 | Yes | ||
| 186 | OGDH | ENSG00000105953.15 | 40859 | -1.805 | -0.1203 | Yes | ||
| 187 | UQCRC2 | ENSG00000140740.11 | 40862 | -1.806 | -0.1109 | Yes | ||
| 188 | ACAA2 | ENSG00000167315.18 | 41011 | -1.873 | -0.1046 | Yes | ||
| 189 | PDHA1 | ENSG00000131828.14 | 41112 | -1.913 | -0.0969 | Yes | ||
| 190 | HSD17B10 | ENSG00000072506.12 | 41554 | -2.165 | -0.0958 | Yes | ||
| 191 | NDUFS2 | ENSG00000158864.12 | 41582 | -2.182 | -0.0851 | Yes | ||
| 192 | COX11 | ENSG00000166260.11 | 41593 | -2.189 | -0.0738 | Yes | ||
| 193 | NDUFAB1 | ENSG00000004779.10 | 41690 | -2.242 | -0.0643 | Yes | ||
| 194 | TIMM8B | ENSG00000150779.12 | 42111 | -2.587 | -0.0606 | Yes | ||
| 195 | COX17 | ENSG00000138495.6 | 42332 | -2.886 | -0.0506 | Yes | ||
| 196 | CYCS | ENSG00000172115.8 | 42546 | -3.206 | -0.0388 | Yes | ||
| 197 | SLC25A4 | ENSG00000151729.11 | 42557 | -3.224 | -0.0222 | Yes | ||
| 198 | IDH2 | ENSG00000182054.9 | 42583 | -3.291 | -0.0056 | Yes | ||
| 199 | ATP1B1 | ENSG00000143153.13 | 42642 | -3.447 | 0.0111 | Yes |
