Details for gene set HALLMARK_PROTEIN_SECRETION[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Phenotype	Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M
Upregulated in class	FSHD2
GeneSet	HALLMARK_PROTEIN_SECRETION
Enrichment Score (ES)	0.25376824
Normalized Enrichment Score (NES)	1.0293187
Nominal p-value	0.39202657
FDR q-value	0.39828065
FWER p-Value	0.995

Fig 1: Enrichment plot: HALLMARK_PROTEIN_SECRETION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	VAMP4	ENSG00000117533.15			205	3.285	0.0355	Yes
2	PAM	ENSG00000145730.20			235	3.193	0.0740	Yes
3	EGFR	ENSG00000146648.18			529	2.570	0.0987	Yes
4	RAB9A	ENSG00000123595.8			1064	2.074	0.1118	Yes
5	SNX2	ENSG00000205302.7			1294	1.944	0.1303	Yes
6	AP3S1	ENSG00000177879.16			1336	1.916	0.1528	Yes
7	BET1	ENSG00000105829.13			2010	1.627	0.1572	Yes
8	CLTA	ENSG00000122705.17			2253	1.549	0.1705	Yes
9	ARFIP1	ENSG00000164144.16			3056	1.320	0.1681	Yes
10	RAB22A	ENSG00000124209.4			3269	1.274	0.1788	Yes
11	ABCA1	ENSG00000165029.16			3576	1.212	0.1865	Yes
12	CLN5	ENSG00000102805.15			3756	1.173	0.1968	Yes
13	STX12	ENSG00000117758.14			4178	1.099	0.2005	Yes
14	SEC22B	ENSG00000265808.4			4338	1.071	0.2099	Yes
15	VPS4B	ENSG00000119541.10			4653	1.022	0.2151	Yes
16	SEC24D	ENSG00000150961.15			5090	0.956	0.2167	Yes
17	AP2B1	ENSG00000006125.18			5163	0.946	0.2266	Yes
18	STX7	ENSG00000079950.14			5400	0.914	0.2324	Yes
19	GLA	ENSG00000102393.10			5414	0.912	0.2433	Yes
20	MON2	ENSG00000061987.16			5442	0.907	0.2538	Yes
21	OCRL	ENSG00000122126.17			5933	0.849	0.2528	No
22	ERGIC3	ENSG00000125991.19			6834	0.754	0.2411	No
23	SCRN1	ENSG00000136193.17			7377	0.703	0.2372	No
24	CTSC	ENSG00000109861.16			7476	0.693	0.2434	No
25	CLCN3	ENSG00000109572.14			8935	0.573	0.2165	No
26	RPS6KA3	ENSG00000177189.14			8961	0.570	0.2229	No
27	ARCN1	ENSG00000095139.14			10081	0.505	0.2031	No
28	SH3GL2	ENSG00000107295.10			10814	0.458	0.1917	No
29	STX16	ENSG00000124222.22			11321	0.426	0.1852	No
30	CD63	ENSG00000135404.11			11956	0.390	0.1752	No
31	CLTC	ENSG00000141367.12			12768	0.357	0.1608	No
32	TMED2	ENSG00000086598.11			13277	0.341	0.1531	No
33	RAB2A	ENSG00000104388.15			14808	0.291	0.1211	No
34	SGMS1	ENSG00000198964.14			15404	0.280	0.1108	No
35	LAMP2	ENSG00000005893.15			16244	0.233	0.0941	No
36	VAMP3	ENSG00000049245.13			16395	0.225	0.0934	No
37	SEC31A	ENSG00000138674.17			16455	0.222	0.0947	No
38	TMED10	ENSG00000170348.9			16564	0.216	0.0949	No
39	ARFGEF2	ENSG00000124198.9			16623	0.213	0.0962	No
40	TSPAN8	ENSG00000127324.9			17421	0.176	0.0798	No
41	ICA1	ENSG00000003147.19			17661	0.166	0.0763	No
42	NAPA	ENSG00000105402.8			17946	0.149	0.0715	No
43	ADAM10	ENSG00000137845.15			18147	0.139	0.0685	No
44	RER1	ENSG00000157916.20			18804	0.107	0.0546	No
45	RAB5A	ENSG00000144566.11			18840	0.105	0.0551	No
46	AP2S1	ENSG00000042753.11			18891	0.104	0.0552	No
47	LMAN1	ENSG00000074695.6			19403	0.077	0.0442	No
48	COPB2	ENSG00000184432.10			19469	0.072	0.0436	No
49	SOD1	ENSG00000142168.14			20939	-0.001	0.0095	No
50	GOSR2	ENSG00000108433.16			21042	-0.006	0.0072	No
51	GALC	ENSG00000054983.17			22503	-0.084	-0.0257	No
52	ARF1	ENSG00000143761.16			22558	-0.088	-0.0259	No
53	ARFGAP3	ENSG00000242247.11			22764	-0.100	-0.0294	No
54	COPB1	ENSG00000129083.12			23227	-0.126	-0.0386	No
55	NAPG	ENSG00000134265.13			24614	-0.205	-0.0683	No
56	YIPF6	ENSG00000181704.12			24772	-0.217	-0.0693	No
57	RAB14	ENSG00000119396.11			25916	-0.255	-0.0927	No
58	AP2M1	ENSG00000161203.13			28129	-0.319	-0.1402	No
59	YKT6	ENSG00000106636.8			28177	-0.321	-0.1374	No
60	ARFGEF1	ENSG00000066777.9			29168	-0.358	-0.1560	No
61	COPE	ENSG00000105669.14			29401	-0.370	-0.1569	No
62	TMX1	ENSG00000139921.13			29739	-0.390	-0.1599	No
63	GBF1	ENSG00000107862.4			29755	-0.391	-0.1555	No
64	KRT18	ENSG00000111057.11			30409	-0.432	-0.1653	No
65	ATP6V1B1	ENSG00000116039.13			31042	-0.463	-0.1743	No
66	PPT1	ENSG00000131238.17			31757	-0.501	-0.1848	No
67	DNM1L	ENSG00000087470.18			32060	-0.519	-0.1855	No
68	ATP6V1H	ENSG00000047249.18			33094	-0.590	-0.2022	No
69	SCAMP3	ENSG00000116521.11			33466	-0.618	-0.2033	No
70	CAV2	ENSG00000105971.15			33613	-0.630	-0.1989	No
71	ZW10	ENSG00000086827.9			33786	-0.643	-0.1950	No
72	DOP1A	ENSG00000083097.14			33806	-0.646	-0.1875	No
73	SCAMP1	ENSG00000085365.18			34556	-0.707	-0.1963	No
74	BNIP3	ENSG00000176171.11			35097	-0.750	-0.1996	No
75	GNAS	ENSG00000087460.25			35113	-0.751	-0.1908	No
76	MAPK1	ENSG00000100030.14			35160	-0.756	-0.1825	No
77	GOLGA4	ENSG00000144674.16			35615	-0.800	-0.1833	No
78	USO1	ENSG00000138768.14			35693	-0.808	-0.1752	No
79	AP3B1	ENSG00000132842.13			36321	-0.880	-0.1789	No
80	IGF2R	ENSG00000197081.14			37384	-1.018	-0.1911	No
81	AP1G1	ENSG00000166747.12			37396	-1.019	-0.1789	No
82	ANP32E	ENSG00000143401.15			37604	-1.051	-0.1708	No
83	M6PR	ENSG00000003056.8			38125	-1.138	-0.1689	No
84	TSG101	ENSG00000074319.13			38589	-1.221	-0.1647	No
85	ATP7A	ENSG00000165240.20			38659	-1.235	-0.1512	No
86	SNAP23	ENSG00000092531.10			38725	-1.249	-0.1374	No
87	VPS45	ENSG00000136631.15			39537	-1.429	-0.1387	No
88	TPD52	ENSG00000076554.15			40238	-1.609	-0.1352	No
89	DST	ENSG00000151914.20			40581	-1.710	-0.1222	No
90	TOM1L1	ENSG00000141198.16			40991	-1.863	-0.1088	No
91	ATP1A1	ENSG00000163399.16			41345	-2.032	-0.0921	No
92	COG2	ENSG00000135775.14			41596	-2.191	-0.0710	No
93	STAM	ENSG00000136738.15			41871	-2.381	-0.0482	No
94	SSPN	ENSG00000123096.11			42412	-2.994	-0.0240	No
95	KIF1B	ENSG00000054523.17			42584	-3.294	0.0124	No

Fig 2: HALLMARK_PROTEIN_SECRETION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: HALLMARK_PROTEIN_SECRETION: Random ES distribution   
Gene set null distribution of ES for HALLMARK_PROTEIN_SECRETION