Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Phenotype | Phenotype.FSHD2.FSHD2M.cls#FSHD2_versus_FSHD2M |
| Upregulated in class | FSHD2M |
| GeneSet | HALLMARK_UV_RESPONSE_UP |
| Enrichment Score (ES) | -0.40978828 |
| Normalized Enrichment Score (NES) | -1.6152724 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0059614517 |
| FWER p-Value | 0.077 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SHOX2 | ENSG00000168779.19 | 40 | 4.232 | 0.0226 | No | ||
| 2 | EPHX1 | ENSG00000143819.12 | 223 | 3.237 | 0.0363 | No | ||
| 3 | IL6ST | ENSG00000134352.20 | 282 | 3.044 | 0.0518 | No | ||
| 4 | NPTXR | ENSG00000221890.4 | 299 | 2.991 | 0.0680 | No | ||
| 5 | MAPK8IP2 | ENSG00000008735.14 | 560 | 2.526 | 0.0760 | No | ||
| 6 | OLFM1 | ENSG00000130558.19 | 825 | 2.239 | 0.0823 | No | ||
| 7 | MSX1 | ENSG00000163132.8 | 976 | 2.117 | 0.0905 | No | ||
| 8 | PLCL1 | ENSG00000115896.16 | 1540 | 1.824 | 0.0876 | No | ||
| 9 | SQSTM1 | ENSG00000161011.20 | 1557 | 1.815 | 0.0973 | No | ||
| 10 | DNAJB1 | ENSG00000132002.8 | 2232 | 1.554 | 0.0902 | No | ||
| 11 | RAB27A | ENSG00000069974.16 | 2248 | 1.551 | 0.0985 | No | ||
| 12 | PPIF | ENSG00000108179.14 | 2376 | 1.511 | 0.1039 | No | ||
| 13 | CDO1 | ENSG00000129596.5 | 2454 | 1.488 | 0.1104 | No | ||
| 14 | TFRC | ENSG00000072274.13 | 2501 | 1.475 | 0.1175 | No | ||
| 15 | IGFBP2 | ENSG00000115457.10 | 2774 | 1.385 | 0.1188 | No | ||
| 16 | RASGRP1 | ENSG00000172575.12 | 3180 | 1.292 | 0.1166 | No | ||
| 17 | BMP2 | ENSG00000125845.7 | 3203 | 1.288 | 0.1232 | No | ||
| 18 | SPR | ENSG00000116096.6 | 3282 | 1.272 | 0.1284 | No | ||
| 19 | IRF1 | ENSG00000125347.14 | 3458 | 1.235 | 0.1312 | No | ||
| 20 | SIGMAR1 | ENSG00000147955.17 | 3873 | 1.151 | 0.1280 | No | ||
| 21 | ICAM1 | ENSG00000090339.9 | 4204 | 1.093 | 0.1264 | No | ||
| 22 | GRINA | ENSG00000178719.17 | 4437 | 1.055 | 0.1268 | No | ||
| 23 | ABCB1 | ENSG00000085563.14 | 4477 | 1.048 | 0.1317 | No | ||
| 24 | FGF18 | ENSG00000156427.8 | 4508 | 1.043 | 0.1368 | No | ||
| 25 | DLG4 | ENSG00000132535.19 | 5218 | 0.937 | 0.1255 | No | ||
| 26 | ATP6V1F | ENSG00000128524.5 | 5271 | 0.931 | 0.1295 | No | ||
| 27 | MGAT1 | ENSG00000131446.16 | 5534 | 0.896 | 0.1283 | No | ||
| 28 | HLA-F | ENSG00000204642.14 | 5664 | 0.881 | 0.1302 | No | ||
| 29 | GAL | ENSG00000069482.7 | 5666 | 0.880 | 0.1351 | No | ||
| 30 | PRKCD | ENSG00000163932.15 | 5863 | 0.856 | 0.1353 | No | ||
| 31 | FMO1 | ENSG00000010932.17 | 6346 | 0.803 | 0.1285 | No | ||
| 32 | CHKA | ENSG00000110721.12 | 6358 | 0.801 | 0.1327 | No | ||
| 33 | CLCN2 | ENSG00000114859.16 | 6557 | 0.783 | 0.1324 | No | ||
| 34 | GCH1 | ENSG00000131979.19 | 7161 | 0.723 | 0.1224 | No | ||
| 35 | BSG | ENSG00000172270.19 | 7390 | 0.702 | 0.1210 | No | ||
| 36 | WIZ | ENSG00000011451.19 | 7450 | 0.695 | 0.1235 | No | ||
| 37 | C4BPB | ENSG00000123843.13 | 7483 | 0.692 | 0.1266 | No | ||
| 38 | GPX3 | ENSG00000211445.12 | 7962 | 0.650 | 0.1191 | No | ||
| 39 | ATP6V1C1 | ENSG00000155097.12 | 7976 | 0.649 | 0.1224 | No | ||
| 40 | CNP | ENSG00000173786.17 | 8781 | 0.585 | 0.1069 | No | ||
| 41 | MMP14 | ENSG00000157227.13 | 9489 | 0.539 | 0.0934 | No | ||
| 42 | HMOX1 | ENSG00000100292.17 | 9579 | 0.532 | 0.0943 | No | ||
| 43 | TST | ENSG00000128311.14 | 9625 | 0.528 | 0.0962 | No | ||
| 44 | FOS | ENSG00000170345.10 | 9664 | 0.525 | 0.0982 | No | ||
| 45 | UROD | ENSG00000126088.14 | 10165 | 0.499 | 0.0893 | No | ||
| 46 | NFKBIA | ENSG00000100906.10 | 10473 | 0.480 | 0.0849 | No | ||
| 47 | LYN | ENSG00000254087.8 | 10784 | 0.460 | 0.0802 | No | ||
| 48 | RXRB | ENSG00000204231.10 | 10840 | 0.456 | 0.0814 | No | ||
| 49 | ACAA1 | ENSG00000060971.18 | 10861 | 0.454 | 0.0835 | No | ||
| 50 | LHX2 | ENSG00000106689.11 | 11660 | 0.404 | 0.0672 | No | ||
| 51 | POLR2H | ENSG00000163882.9 | 12205 | 0.377 | 0.0566 | No | ||
| 52 | RET | ENSG00000165731.20 | 12408 | 0.369 | 0.0539 | No | ||
| 53 | TAP1 | ENSG00000168394.11 | 14010 | 0.316 | 0.0184 | No | ||
| 54 | HSPA2 | ENSG00000126803.9 | 14084 | 0.312 | 0.0185 | No | ||
| 55 | BTG1 | ENSG00000133639.5 | 14119 | 0.310 | 0.0194 | No | ||
| 56 | TYRO3 | ENSG00000092445.12 | 15440 | 0.279 | -0.0098 | No | ||
| 57 | ONECUT1 | ENSG00000169856.9 | 16586 | 0.215 | -0.0352 | No | ||
| 58 | TMBIM6 | ENSG00000139644.13 | 17875 | 0.153 | -0.0644 | No | ||
| 59 | STARD3 | ENSG00000131748.16 | 17944 | 0.149 | -0.0651 | No | ||
| 60 | NXF1 | ENSG00000162231.14 | 18292 | 0.131 | -0.0725 | No | ||
| 61 | AP2S1 | ENSG00000042753.11 | 18891 | 0.104 | -0.0858 | No | ||
| 62 | MRPL23 | ENSG00000214026.11 | 19983 | 0.048 | -0.1110 | No | ||
| 63 | EPCAM | ENSG00000119888.10 | 21429 | -0.028 | -0.1444 | No | ||
| 64 | H2AFX | ENSG00000188486.3 | 21679 | -0.041 | -0.1500 | No | ||
| 65 | CDKN2B | ENSG00000147883.12 | 21714 | -0.043 | -0.1506 | No | ||
| 66 | PPP1R2 | ENSG00000184203.8 | 21937 | -0.053 | -0.1554 | No | ||
| 67 | NAT1 | ENSG00000171428.14 | 23098 | -0.118 | -0.1818 | No | ||
| 68 | DNAJA1 | ENSG00000086061.16 | 23161 | -0.122 | -0.1825 | No | ||
| 69 | CXCL2 | ENSG00000081041.9 | 23850 | -0.161 | -0.1977 | No | ||
| 70 | SOD2 | ENSG00000112096.18 | 24563 | -0.202 | -0.2131 | No | ||
| 71 | HYAL2 | ENSG00000068001.14 | 24832 | -0.220 | -0.2181 | No | ||
| 72 | ATF3 | ENSG00000162772.17 | 25795 | -0.246 | -0.2392 | No | ||
| 73 | FOSB | ENSG00000125740.14 | 25850 | -0.250 | -0.2390 | No | ||
| 74 | CCND3 | ENSG00000112576.12 | 26472 | -0.264 | -0.2520 | No | ||
| 75 | APOM | ENSG00000204444.11 | 27098 | -0.281 | -0.2650 | No | ||
| 76 | CEBPG | ENSG00000153879.9 | 27230 | -0.290 | -0.2664 | No | ||
| 77 | YKT6 | ENSG00000106636.8 | 28177 | -0.321 | -0.2867 | No | ||
| 78 | MAOA | ENSG00000189221.9 | 29884 | -0.397 | -0.3242 | No | ||
| 79 | E2F5 | ENSG00000133740.11 | 30537 | -0.437 | -0.3369 | No | ||
| 80 | CYB5B | ENSG00000103018.16 | 30781 | -0.453 | -0.3401 | No | ||
| 81 | CYP1A1 | ENSG00000140465.14 | 31019 | -0.461 | -0.3430 | No | ||
| 82 | HNRNPU | ENSG00000153187.20 | 31095 | -0.467 | -0.3422 | No | ||
| 83 | ASNS | ENSG00000070669.17 | 31521 | -0.490 | -0.3494 | No | ||
| 84 | PPT1 | ENSG00000131238.17 | 31757 | -0.501 | -0.3521 | No | ||
| 85 | EIF5 | ENSG00000100664.11 | 32207 | -0.527 | -0.3596 | No | ||
| 86 | POLG2 | ENSG00000256525.8 | 32683 | -0.558 | -0.3675 | No | ||
| 87 | PPAT | ENSG00000128059.8 | 32899 | -0.576 | -0.3694 | No | ||
| 88 | TGFBRAP1 | ENSG00000135966.13 | 33501 | -0.622 | -0.3799 | No | ||
| 89 | CCK | ENSG00000187094.12 | 33968 | -0.660 | -0.3871 | No | ||
| 90 | NR4A1 | ENSG00000123358.20 | 34316 | -0.685 | -0.3914 | No | ||
| 91 | PRPF3 | ENSG00000117360.13 | 34441 | -0.697 | -0.3904 | No | ||
| 92 | JUNB | ENSG00000171223.6 | 34828 | -0.728 | -0.3953 | No | ||
| 93 | NTRK3 | ENSG00000140538.16 | 34869 | -0.731 | -0.3922 | No | ||
| 94 | MARK2 | ENSG00000072518.20 | 35626 | -0.801 | -0.4053 | Yes | ||
| 95 | CHRNA5 | ENSG00000169684.13 | 35639 | -0.803 | -0.4012 | Yes | ||
| 96 | BAK1 | ENSG00000030110.13 | 35677 | -0.806 | -0.3976 | Yes | ||
| 97 | ARRB2 | ENSG00000141480.18 | 35735 | -0.812 | -0.3944 | Yes | ||
| 98 | DGAT1 | ENSG00000185000.12 | 35854 | -0.825 | -0.3925 | Yes | ||
| 99 | HSPA13 | ENSG00000155304.6 | 36046 | -0.849 | -0.3923 | Yes | ||
| 100 | AMD1 | ENSG00000123505.17 | 36105 | -0.856 | -0.3889 | Yes | ||
| 101 | BTG3 | ENSG00000154640.14 | 36393 | -0.887 | -0.3906 | Yes | ||
| 102 | TARS | ENSG00000113407.13 | 36534 | -0.904 | -0.3889 | Yes | ||
| 103 | TACR3 | ENSG00000169836.5 | 36611 | -0.917 | -0.3856 | Yes | ||
| 104 | CA2 | ENSG00000104267.10 | 36626 | -0.919 | -0.3808 | Yes | ||
| 105 | TCHH | ENSG00000159450.12 | 37011 | -0.967 | -0.3844 | Yes | ||
| 106 | CDK2 | ENSG00000123374.11 | 37047 | -0.974 | -0.3798 | Yes | ||
| 107 | BTG2 | ENSG00000159388.6 | 37157 | -0.987 | -0.3768 | Yes | ||
| 108 | EIF2S3 | ENSG00000130741.11 | 37332 | -1.010 | -0.3753 | Yes | ||
| 109 | IL6 | ENSG00000136244.12 | 37366 | -1.015 | -0.3704 | Yes | ||
| 110 | PRKACA | ENSG00000072062.14 | 37389 | -1.018 | -0.3653 | Yes | ||
| 111 | TUBA4A | ENSG00000127824.14 | 37405 | -1.021 | -0.3600 | Yes | ||
| 112 | FURIN | ENSG00000140564.12 | 37563 | -1.044 | -0.3578 | Yes | ||
| 113 | BID | ENSG00000015475.18 | 37741 | -1.075 | -0.3560 | Yes | ||
| 114 | ALAS1 | ENSG00000023330.15 | 37768 | -1.078 | -0.3506 | Yes | ||
| 115 | RFC4 | ENSG00000163918.10 | 37809 | -1.085 | -0.3455 | Yes | ||
| 116 | PTPRD | ENSG00000153707.17 | 37937 | -1.106 | -0.3423 | Yes | ||
| 117 | RPN1 | ENSG00000163902.12 | 37998 | -1.117 | -0.3375 | Yes | ||
| 118 | PDAP1 | ENSG00000106244.13 | 38373 | -1.183 | -0.3397 | Yes | ||
| 119 | FEN1 | ENSG00000168496.4 | 38431 | -1.194 | -0.3344 | Yes | ||
| 120 | CREG1 | ENSG00000143162.9 | 38436 | -1.195 | -0.3278 | Yes | ||
| 121 | RHOB | ENSG00000143878.10 | 38518 | -1.210 | -0.3230 | Yes | ||
| 122 | GGH | ENSG00000137563.12 | 38545 | -1.214 | -0.3169 | Yes | ||
| 123 | CDC34 | ENSG00000099804.9 | 38568 | -1.218 | -0.3106 | Yes | ||
| 124 | ALDOA | ENSG00000149925.20 | 38602 | -1.223 | -0.3046 | Yes | ||
| 125 | SLC6A8 | ENSG00000130821.16 | 38709 | -1.245 | -0.3002 | Yes | ||
| 126 | CDC5L | ENSG00000096401.8 | 38949 | -1.298 | -0.2985 | Yes | ||
| 127 | KLHDC3 | ENSG00000124702.18 | 39020 | -1.314 | -0.2929 | Yes | ||
| 128 | NPTX2 | ENSG00000106236.4 | 39547 | -1.430 | -0.2972 | Yes | ||
| 129 | POLE3 | ENSG00000148229.13 | 39649 | -1.454 | -0.2914 | Yes | ||
| 130 | ENO2 | ENSG00000111674.9 | 39689 | -1.464 | -0.2842 | Yes | ||
| 131 | PARP2 | ENSG00000129484.13 | 39746 | -1.477 | -0.2773 | Yes | ||
| 132 | NKX2-5 | ENSG00000183072.10 | 39974 | -1.542 | -0.2741 | Yes | ||
| 133 | AGO2 | ENSG00000123908.12 | 40436 | -1.667 | -0.2755 | Yes | ||
| 134 | GRPEL1 | ENSG00000109519.13 | 40485 | -1.684 | -0.2673 | Yes | ||
| 135 | COL2A1 | ENSG00000139219.19 | 40754 | -1.768 | -0.2637 | Yes | ||
| 136 | GLS | ENSG00000115419.12 | 40819 | -1.790 | -0.2553 | Yes | ||
| 137 | SULT1A1 | ENSG00000196502.11 | 40850 | -1.802 | -0.2460 | Yes | ||
| 138 | CTSV | ENSG00000136943.11 | 41043 | -1.887 | -0.2400 | Yes | ||
| 139 | FKBP4 | ENSG00000004478.8 | 41079 | -1.899 | -0.2303 | Yes | ||
| 140 | STK25 | ENSG00000115694.15 | 41121 | -1.918 | -0.2206 | Yes | ||
| 141 | CDKN1C | ENSG00000129757.13 | 41169 | -1.945 | -0.2109 | Yes | ||
| 142 | STIP1 | ENSG00000168439.16 | 41211 | -1.963 | -0.2010 | Yes | ||
| 143 | CCNE1 | ENSG00000105173.14 | 41239 | -1.974 | -0.1906 | Yes | ||
| 144 | PSMC3 | ENSG00000165916.8 | 41467 | -2.112 | -0.1842 | Yes | ||
| 145 | BCL2L11 | ENSG00000153094.23 | 41506 | -2.133 | -0.1732 | Yes | ||
| 146 | CLTB | ENSG00000175416.13 | 41519 | -2.140 | -0.1616 | Yes | ||
| 147 | SLC6A12 | ENSG00000111181.12 | 41546 | -2.160 | -0.1503 | Yes | ||
| 148 | HTR7 | ENSG00000148680.16 | 41585 | -2.184 | -0.1390 | Yes | ||
| 149 | SELENOW | ENSG00000178980.15 | 41610 | -2.199 | -0.1274 | Yes | ||
| 150 | NUP58 | ENSG00000139496.16 | 41803 | -2.330 | -0.1189 | Yes | ||
| 151 | KCNH2 | ENSG00000055118.15 | 41985 | -2.477 | -0.1094 | Yes | ||
| 152 | DDX21 | ENSG00000165732.13 | 42089 | -2.560 | -0.0976 | Yes | ||
| 153 | RRAD | ENSG00000166592.12 | 42226 | -2.740 | -0.0855 | Yes | ||
| 154 | CASP3 | ENSG00000164305.19 | 42313 | -2.869 | -0.0716 | Yes | ||
| 155 | SLC25A4 | ENSG00000151729.11 | 42557 | -3.224 | -0.0594 | Yes | ||
| 156 | AQP3 | ENSG00000165272.16 | 42764 | -3.770 | -0.0433 | Yes | ||
| 157 | CYB5R1 | ENSG00000159348.13 | 42905 | -4.301 | -0.0226 | Yes | ||
| 158 | PDLIM3 | ENSG00000154553.15 | 43113 | -4.975 | 0.0001 | Yes |
