- Exposome
  1. drop ppl w.
     * body hight      <= 40
     * body mass index <= 15
  2. drop items about           (1848 ->  6??)
     * medication
     * not applicable as exposure (time, addr, text, etc.)

- Genotypes
  1. drop ppl to break kinship  (47?? -> 4610)
  2. drop variants w.           (45 M -> 11 M)
     * missing > 0.05
     * MAF     < 0.01
     * HWE-p   > 1e-9
  3. drop ppl w. missing > 0.05 (4610 -> 46??)