Simulation - five figures to show simulation results. * Figure 1a: Gaussian phenotypes * Figure 1b: Balanced Binary (50% case rate) * Figure 1c: imbalanced Binary (78% case rate) * Figure 1d, 1e: Poisson phenotypes (37% and 92% zeros). Flow charts - flowcharts for analytical pipelines * internal GxE enrichment analysis * external GxE enrichment analysis (PEGS GxE-WAS included) * functional enrichment analysis * creation of VLA-Catalog * using the Cata-log * (pending) PEGS 2-way GxE-WAS in greater detail * (pending) adjust PEGS GxE p-values by putative GxE statistics (i.e., VLA's p-value).