Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 0 |
| GeneSet | GO_HISTONE_H3_DEACETYLATION |
| Enrichment Score (ES) | -0.5461578 |
| Normalized Enrichment Score (NES) | -1.7064233 |
| Nominal p-value | 0.03629032 |
| FDR q-value | 0.9758187 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PER2 | PER2 Entrez, Source | period homolog 2 (Drosophila) | 9202 | 0.035 | -0.3870 | No |
| 2 | HDAC4 | HDAC4 Entrez, Source | histone deacetylase 4 | 10557 | 0.020 | -0.4228 | No |
| 3 | HDAC2 | HDAC2 Entrez, Source | histone deacetylase 2 | 10805 | 0.018 | -0.4093 | No |
| 4 | ELK4 | ELK4 Entrez, Source | ELK4, ETS-domain protein (SRF accessory protein 1) | 10819 | 0.018 | -0.3849 | No |
| 5 | SMARCAD1 | SMARCAD1 Entrez, Source | SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 | 11554 | 0.011 | -0.4043 | No |
| 6 | HDAC6 | HDAC6 Entrez, Source | histone deacetylase 6 | 12960 | -0.001 | -0.4689 | No |
| 7 | HDAC8 | HDAC8 Entrez, Source | histone deacetylase 8 | 13394 | -0.005 | -0.4823 | No |
| 8 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13578 | -0.007 | -0.4817 | No |
| 9 | SIRT7 | SIRT7 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) | 14003 | -0.010 | -0.4872 | No |
| 10 | HDAC7 | 14704 | -0.016 | -0.4978 | No | ||
| 11 | SIRT2 | SIRT2 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 15727 | -0.025 | -0.5111 | Yes |
| 12 | HDAC3 | HDAC3 Entrez, Source | histone deacetylase 3 | 15870 | -0.026 | -0.4809 | Yes |
| 13 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 16184 | -0.029 | -0.4549 | Yes |
| 14 | ATXN3 | ATXN3 Entrez, Source | ataxin 3 | 16496 | -0.032 | -0.4246 | Yes |
| 15 | HDAC1 | HDAC1 Entrez, Source | histone deacetylase 1 | 17331 | -0.041 | -0.4063 | Yes |
| 16 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 17816 | -0.048 | -0.3620 | Yes |
| 17 | HDAC9 | HDAC9 Entrez, Source | histone deacetylase 9 | 17898 | -0.049 | -0.2970 | Yes |
| 18 | SIRT6 | SIRT6 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) | 17943 | -0.050 | -0.2294 | Yes |
| 19 | HDAC10 | HDAC10 Entrez, Source | histone deacetylase 10 | 17975 | -0.051 | -0.1604 | Yes |
| 20 | SIRT3 | SIRT3 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) | 18927 | -0.069 | -0.1094 | Yes |
| 21 | HDAC11 | HDAC11 Entrez, Source | histone deacetylase 11 | 19169 | -0.076 | -0.0153 | Yes |
| 22 | SIRT1 | SIRT1 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) | 19249 | -0.078 | 0.0897 | Yes |
