Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 0 |
| GeneSet | GO_LAMIN_BINDING |
| Enrichment Score (ES) | -0.6263691 |
| Normalized Enrichment Score (NES) | -1.8455812 |
| Nominal p-value | 0.008130081 |
| FDR q-value | 0.51511747 |
| FWER p-Value | 0.892 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LBR | LBR Entrez, Source | lamin B receptor | 12419 | 0.003 | -0.5808 | No |
| 2 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 12545 | 0.002 | -0.5818 | No |
| 3 | TMPO | TMPO Entrez, Source | thymopoietin | 12865 | -0.001 | -0.5957 | No |
| 4 | HNRNPK | 13513 | -0.006 | -0.6129 | Yes | ||
| 5 | PPP4C | PPP4C Entrez, Source | protein phosphatase 4 (formerly X), catalytic subunit | 13722 | -0.008 | -0.6049 | Yes |
| 6 | SUN2 | 13927 | -0.010 | -0.5920 | Yes | ||
| 7 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 13971 | -0.010 | -0.5709 | Yes |
| 8 | SUN1 | 14596 | -0.015 | -0.5662 | Yes | ||
| 9 | IFI27 | IFI27 Entrez, Source | interferon, alpha-inducible protein 27 | 15021 | -0.019 | -0.5438 | Yes |
| 10 | SYNE1 | SYNE1 Entrez, Source | spectrin repeat containing, nuclear envelope 1 | 15965 | -0.027 | -0.5269 | Yes |
| 11 | NARF | NARF Entrez, Source | nuclear prelamin A recognition factor | 16869 | -0.036 | -0.4880 | Yes |
| 12 | AKAP8L | AKAP8L Entrez, Source | A kinase (PRKA) anchor protein 8-like | 16872 | -0.036 | -0.4064 | Yes |
| 13 | TOR1AIP1 | TOR1AIP1 Entrez, Source | torsin A interacting protein 1 | 17251 | -0.041 | -0.3327 | Yes |
| 14 | TMEM201 | 17552 | -0.044 | -0.2469 | Yes | ||
| 15 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 18063 | -0.052 | -0.1543 | Yes |
| 16 | PKP1 | PKP1 Entrez, Source | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 18136 | -0.053 | -0.0382 | Yes |
| 17 | PLCB1 | PLCB1 Entrez, Source | phospholipase C, beta 1 (phosphoinositide-specific) | 19307 | -0.080 | 0.0869 | Yes |
