Details for gene set GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos
Phenotype	NOV0093.cls#obese_versus_normal_repos
Upregulated in class	1
GeneSet	GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	0.68931663
Normalized Enrichment Score (NES)	2.1268325
Nominal p-value	0.0
FDR q-value	0.21252237
FWER p-Value	0.262

Fig 1: Enrichment plot: GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	BTK	BTK Entrez,  Source	Bruton agammaglobulinemia tyrosine kinase	28	0.412	0.1245	Yes
2	TLR6	TLR6 Entrez,  Source	toll-like receptor 6	104	0.365	0.2323	Yes
3	TLR8	TLR8 Entrez,  Source	toll-like receptor 8	144	0.346	0.3361	Yes
4	TLR7	TLR7 Entrez,  Source	toll-like receptor 7	292	0.306	0.4228	Yes
5	TLR10	TLR10 Entrez,  Source	toll-like receptor 10	1131	0.220	0.4502	Yes
6	TLR2	TLR2 Entrez,  Source	toll-like receptor 2	1778	0.188	0.4771	Yes
7	TLR1	TLR1 Entrez,  Source	toll-like receptor 1	1968	0.181	0.5234	Yes
8	CD14	CD14 Entrez,  Source	CD14 molecule	2213	0.172	0.5643	Yes
9	TIRAP	TIRAP Entrez,  Source	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	2521	0.163	0.5996	Yes
10	TLR5	TLR5 Entrez,  Source	toll-like receptor 5	2606	0.160	0.6445	Yes
11	LY96	LY96 Entrez,  Source	lymphocyte antigen 96	2680	0.158	0.6893	Yes
12	IRAK2	IRAK2 Entrez,  Source	interleukin-1 receptor-associated kinase 2	7265	0.063	0.4916	No
13	MYD88	MYD88 Entrez,  Source	myeloid differentiation primary response gene (88)	8547	0.044	0.4442	No
14	HSPD1	HSPD1 Entrez,  Source	heat shock 60kDa protein 1 (chaperonin)	8556	0.044	0.4572	No
15	IRAK1	IRAK1 Entrez,  Source	interleukin-1 receptor-associated kinase 1	9314	0.034	0.4316	No
16	TNIP1	TNIP1 Entrez,  Source	TNFAIP3 interacting protein 1	10197	0.024	0.3971	No
17	TLR4	TLR4 Entrez,  Source	toll-like receptor 4	10488	0.021	0.3898	No
18	MAP3K1	MAP3K1 Entrez,  Source	mitogen-activated protein kinase kinase kinase 1	10662	0.019	0.3875	No
19	TAB2			10793	0.018	0.3869	No
20	UBC	UBC Entrez,  Source	ubiquitin C	12666	0.001	0.2986	No
21	TRAF6	TRAF6 Entrez,  Source	TNF receptor-associated factor 6	13413	-0.005	0.2649	No
22	CD36	CD36 Entrez,  Source	CD36 molecule (thrombospondin receptor)	14295	-0.013	0.2271	No
23	UBA52	UBA52 Entrez,  Source	ubiquitin A-52 residue ribosomal protein fusion product 1	15098	-0.020	0.1951	No
24	TAB1			15285	-0.021	0.1928	No
25	MAP3K7	MAP3K7 Entrez,  Source	mitogen-activated protein kinase kinase kinase 7	15371	-0.022	0.1955	No
26	TAB3			15818	-0.026	0.1823	No
27	UBB	UBB Entrez,  Source	ubiquitin B	15940	-0.027	0.1849	No
28	RPS27A	RPS27A Entrez,  Source	ribosomal protein S27a	16508	-0.032	0.1679	No
29	IRAK4	IRAK4 Entrez,  Source	interleukin-1 receptor-associated kinase 4	17589	-0.045	0.1305	No
30	IRAK3	IRAK3 Entrez,  Source	interleukin-1 receptor-associated kinase 3	20304	-0.124	0.0398	No

Fig 2: GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY