Details for gene set GO_PHAGOCYTIC_VESICLE[GSEA]

Table: GSEA Results Summary

Dataset	NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos
Phenotype	NOV0093.cls#obese_versus_normal_repos
Upregulated in class	1
GeneSet	GO_PHAGOCYTIC_VESICLE
Enrichment Score (ES)	0.5427138
Normalized Enrichment Score (NES)	2.1402547
Nominal p-value	0.0
FDR q-value	0.25282398
FWER p-Value	0.238

Fig 1: Enrichment plot: GO_PHAGOCYTIC_VESICLE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NCF1	NCF1 Entrez,  Source	neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)	21	0.420	0.0611	Yes
2	TLR6	TLR6 Entrez,  Source	toll-like receptor 6	104	0.365	0.1112	Yes
3	NCF4	NCF4 Entrez,  Source	neutrophil cytosolic factor 4, 40kDa	139	0.348	0.1611	Yes
4	NCF2	NCF2 Entrez,  Source	neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)	203	0.327	0.2065	Yes
5	CYBB	CYBB Entrez,  Source	cytochrome b-245, beta polypeptide (chronic granulomatous disease)	219	0.323	0.2536	Yes
6	TLR7	TLR7 Entrez,  Source	toll-like receptor 7	292	0.306	0.2956	Yes
7	SLC11A1	SLC11A1 Entrez,  Source	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	360	0.294	0.3360	Yes
8	RAB23	RAB23 Entrez,  Source	RAB23, member RAS oncogene family	372	0.293	0.3788	Yes
9	RAC2	RAC2 Entrez,  Source	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	1005	0.228	0.3826	Yes
10	HLA-G	HLA-G Entrez,  Source	HLA-G histocompatibility antigen, class I, G	1253	0.212	0.4023	Yes
11	RAB9B	RAB9B Entrez,  Source	RAB9B, member RAS oncogene family	1634	0.194	0.4129	Yes
12	SYK	SYK Entrez,  Source	spleen tyrosine kinase	1640	0.194	0.4414	Yes
13	TLR2	TLR2 Entrez,  Source	toll-like receptor 2	1778	0.188	0.4627	Yes
14	SLAMF1	SLAMF1 Entrez,  Source	signaling lymphocytic activation molecule family member 1	1838	0.186	0.4874	Yes
15	TLR1	TLR1 Entrez,  Source	toll-like receptor 1	1968	0.181	0.5081	Yes
16	FMNL1	FMNL1 Entrez,  Source	formin-like 1	2087	0.176	0.5285	Yes
17	RAB11FIP1	RAB11FIP1 Entrez,  Source	RAB11 family interacting protein 1 (class I)	2472	0.164	0.5346	Yes
18	HLA-H	HLA-H Entrez,  Source	major histocompatibility complex, class I, H (pseudogene)	2877	0.153	0.5380	Yes
19	CORO1A	CORO1A Entrez,  Source	coronin, actin binding protein, 1A	3235	0.143	0.5422	Yes
20	CYBA	CYBA Entrez,  Source	cytochrome b-245, alpha polypeptide	3890	0.127	0.5300	Yes
21	ADAM8	ADAM8 Entrez,  Source	ADAM metallopeptidase domain 8	4010	0.124	0.5427	Yes
22	RAB38	RAB38 Entrez,  Source	RAB38, member RAS oncogene family	5644	0.091	0.4787	No
23	RAB31	RAB31 Entrez,  Source	RAB31, member RAS oncogene family	6268	0.080	0.4609	No
24	RAB8A	RAB8A Entrez,  Source	RAB8A, member RAS oncogene family	6768	0.071	0.4478	No
25	CLCN3	CLCN3 Entrez,  Source	chloride channel 3	7491	0.060	0.4223	No
26	RAB8B	RAB8B Entrez,  Source	RAB8B, member RAS oncogene family	7530	0.059	0.4293	No
27	ITGAV	ITGAV Entrez,  Source	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	7925	0.053	0.4184	No
28	STX6	STX6 Entrez,  Source	syntaxin 6	8338	0.047	0.4057	No
29	ATP6V0E2	ATP6V0E2 Entrez,  Source	ATPase, H+ transporting V0 subunit e2	8497	0.045	0.4048	No
30	RAB43	RAB43 Entrez,  Source	RAB43, member RAS oncogene family	8734	0.041	0.3997	No
31	SYT7	SYT7 Entrez,  Source	synaptotagmin VII	8826	0.040	0.4013	No
32	RAB32	RAB32 Entrez,  Source	RAB32, member RAS oncogene family	8911	0.039	0.4030	No
33	ITGB5	ITGB5 Entrez,  Source	integrin, beta 5	9045	0.037	0.4022	No
34	ANXA3	ANXA3 Entrez,  Source	annexin A3	9095	0.036	0.4052	No
35	ATP6V0C	ATP6V0C Entrez,  Source	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	9466	0.032	0.3924	No
36	DMBT1	DMBT1 Entrez,  Source	deleted in malignant brain tumors 1	10284	0.023	0.3570	No
37	PIK3R4	PIK3R4 Entrez,  Source	phosphoinositide-3-kinase, regulatory subunit 4, p150	10298	0.023	0.3598	No
38	UNC93B1	UNC93B1 Entrez,  Source	unc-93 homolog B1 (C. elegans)	10829	0.018	0.3372	No
39	BECN1	BECN1 Entrez,  Source	beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)	10915	0.017	0.3357	No
40	ATP6V0D1	ATP6V0D1 Entrez,  Source	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	11081	0.016	0.3302	No
41	RAB9A			11094	0.016	0.3319	No
42	TCIRG1	TCIRG1 Entrez,  Source	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	11175	0.015	0.3303	No
43	RAB10	RAB10 Entrez,  Source	RAB10, member RAS oncogene family	11254	0.014	0.3287	No
44	LAMP1	LAMP1 Entrez,  Source	lysosomal-associated membrane protein 1	11257	0.014	0.3307	No
45	ATP6V0E1	ATP6V0E1 Entrez,  Source	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1	11305	0.013	0.3304	No
46	OCRL	OCRL Entrez,  Source	oculocerebrorenal syndrome of Lowe	11873	0.008	0.3047	No
47	ATP6V0A1	ATP6V0A1 Entrez,  Source	ATPase, H+ transporting, lysosomal V0 subunit a1	12150	0.005	0.2924	No
48	LAMP2	LAMP2 Entrez,  Source	lysosomal-associated membrane protein 2	12355	0.004	0.2833	No
49	ANXA11	ANXA11 Entrez,  Source	annexin A11	12633	0.001	0.2703	No
50	SRGAP2	SRGAP2 Entrez,  Source	SLIT-ROBO Rho GTPase activating protein 2	12880	-0.001	0.2588	No
51	RAB22A	RAB22A Entrez,  Source	RAB22A, member RAS oncogene family	12919	-0.001	0.2571	No
52	RAB11A	RAB11A Entrez,  Source	RAB11A, member RAS oncogene family	13334	-0.004	0.2381	No
53	RAB14	RAB14 Entrez,  Source	RAB14, member RAS oncogene family	13516	-0.006	0.2304	No
54	RAB7A			13670	-0.007	0.2243	No
55	PIK3C3	PIK3C3 Entrez,  Source	phosphoinositide-3-kinase, class 3	13944	-0.010	0.2128	No
56	UVRAG	UVRAG Entrez,  Source	UV radiation resistance associated gene	14113	-0.011	0.2065	No
57	STX12	STX12 Entrez,  Source	syntaxin 12	14258	-0.013	0.2015	No
58	CD36	CD36 Entrez,  Source	CD36 molecule (thrombospondin receptor)	14295	-0.013	0.2017	No
59	HLA-B	HLA-B Entrez,  Source	major histocompatibility complex, class I, B	14319	-0.013	0.2026	No
60	RAB5A	RAB5A Entrez,  Source	RAB5A, member RAS oncogene family	14693	-0.016	0.1872	No
61	ATG5	ATG5 Entrez,  Source	ATG5 autophagy related 5 homolog (S. cerevisiae)	15288	-0.021	0.1622	No
62	SNX3	SNX3 Entrez,  Source	sorting nexin 3	15418	-0.022	0.1594	No
63	RAB34	RAB34 Entrez,  Source	RAB34, member RAS oncogene family	15578	-0.024	0.1554	No
64	B2M	B2M Entrez,  Source	beta-2-microglobulin	16102	-0.029	0.1348	No
65	AMBRA1			16177	-0.029	0.1356	No
66	RAB20	RAB20 Entrez,  Source	RAB20, member RAS oncogene family	16261	-0.030	0.1361	No
67	HLA-A	HLA-A Entrez,  Source	major histocompatibility complex, class I, A	16326	-0.031	0.1377	No
68	ATP6V0A2	ATP6V0A2 Entrez,  Source	ATPase, H+ transporting, lysosomal V0 subunit a2	16346	-0.031	0.1414	No
69	HLA-C	HLA-C Entrez,  Source	major histocompatibility complex, class I, C	16751	-0.035	0.1274	No
70	RAB11B	RAB11B Entrez,  Source	RAB11B, member RAS oncogene family	16787	-0.035	0.1310	No
71	INPP5B	INPP5B Entrez,  Source	inositol polyphosphate-5-phosphatase, 75kDa	16859	-0.036	0.1329	No
72	ATP6V0B	ATP6V0B Entrez,  Source	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	16966	-0.037	0.1334	No
73	ATG12	ATG12 Entrez,  Source	ATG12 autophagy related 12 homolog (S. cerevisiae)	17057	-0.038	0.1348	No
74	ATG14			17231	-0.040	0.1326	No
75	ABCA1	ABCA1 Entrez,  Source	ATP-binding cassette, sub-family A (ABC1), member 1	17369	-0.042	0.1323	No
76	ATP6V0A4	ATP6V0A4 Entrez,  Source	ATPase, H+ transporting, lysosomal V0 subunit a4	17440	-0.043	0.1353	No
77	LTF	LTF Entrez,  Source	lactotransferrin	18416	-0.058	0.0977	No
78	HLA-E	HLA-E Entrez,  Source	major histocompatibility complex, class I, E	18485	-0.059	0.1032	No
79	HLA-F	HLA-F Entrez,  Source	major histocompatibility complex, class I, F	19036	-0.072	0.0877	No
80	RILP	RILP Entrez,  Source	Rab interacting lysosomal protein	19403	-0.083	0.0826	No

Fig 2: GO_PHAGOCYTIC_VESICLE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: GO_PHAGOCYTIC_VESICLE: Random ES distribution   
Gene set null distribution of ES for GO_PHAGOCYTIC_VESICLE