Details for gene set GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE[GSEA]

Table: GSEA Results Summary

Dataset	NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos
Phenotype	NOV0093.cls#obese_versus_normal_repos
Upregulated in class	1
GeneSet	GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE
Enrichment Score (ES)	0.50469697
Normalized Enrichment Score (NES)	2.2150261
Nominal p-value	0.001980198
FDR q-value	0.23463507
FWER p-Value	0.133

Fig 1: Enrichment plot: GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ITGAM	ITGAM Entrez,  Source	integrin, alpha M (complement component 3 receptor 3 subunit)	13	0.442	0.0227	Yes
2	PIK3AP1	PIK3AP1 Entrez,  Source	phosphoinositide-3-kinase adaptor protein 1	25	0.416	0.0441	Yes
3	BTK	BTK Entrez,  Source	Bruton agammaglobulinemia tyrosine kinase	28	0.412	0.0658	Yes
4	VAV1	VAV1 Entrez,  Source	vav 1 oncogene	32	0.405	0.0870	Yes
5	CD86	CD86 Entrez,  Source	CD86 molecule	41	0.398	0.1076	Yes
6	NLRC4			78	0.376	0.1258	Yes
7	TLR6	TLR6 Entrez,  Source	toll-like receptor 6	104	0.365	0.1438	Yes
8	CD209	CD209 Entrez,  Source	CD209 molecule	110	0.362	0.1627	Yes
9	TLR8	TLR8 Entrez,  Source	toll-like receptor 8	144	0.346	0.1793	Yes
10	CLEC7A	CLEC7A Entrez,  Source	C-type lectin domain family 7, member A	171	0.336	0.1958	Yes
11	MARCO	MARCO Entrez,  Source	macrophage receptor with collagenous structure	276	0.309	0.2072	Yes
12	TLR7	TLR7 Entrez,  Source	toll-like receptor 7	292	0.306	0.2227	Yes
13	EREG	EREG Entrez,  Source	epiregulin	294	0.306	0.2388	Yes
14	HCK	HCK Entrez,  Source	hemopoietic cell kinase	300	0.306	0.2547	Yes
15	LBP	LBP Entrez,  Source	lipopolysaccharide binding protein	391	0.290	0.2657	Yes
16	FCER1G	FCER1G Entrez,  Source	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	421	0.286	0.2794	Yes
17	ITGB2	ITGB2 Entrez,  Source	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	433	0.284	0.2939	Yes
18	HAVCR2	HAVCR2 Entrez,  Source	hepatitis A virus cellular receptor 2	463	0.279	0.3073	Yes
19	NOD2			948	0.232	0.2963	Yes
20	FCN1	FCN1 Entrez,  Source	ficolin (collagen/fibrinogen domain containing) 1	1006	0.228	0.3057	Yes
21	CD180	CD180 Entrez,  Source	CD180 molecule	1012	0.228	0.3174	Yes
22	IKBKE	IKBKE Entrez,  Source	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	1083	0.223	0.3258	Yes
23	SCARA3	SCARA3 Entrez,  Source	scavenger receptor class A, member 3	1106	0.222	0.3365	Yes
24	TLR10	TLR10 Entrez,  Source	toll-like receptor 10	1131	0.220	0.3469	Yes
25	SLAMF6	SLAMF6 Entrez,  Source	SLAM family member 6	1150	0.219	0.3576	Yes
26	CD1D	CD1D Entrez,  Source	CD1d molecule	1158	0.218	0.3688	Yes
27	LGMN	LGMN Entrez,  Source	legumain	1335	0.209	0.3714	Yes
28	COCH	COCH Entrez,  Source	coagulation factor C homolog, cochlin (Limulus polyphemus)	1372	0.206	0.3805	Yes
29	RASGRP1	RASGRP1 Entrez,  Source	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	1470	0.201	0.3865	Yes
30	CARD9	CARD9 Entrez,  Source	caspase recruitment domain family, member 9	1535	0.199	0.3939	Yes
31	SYK	SYK Entrez,  Source	spleen tyrosine kinase	1640	0.194	0.3992	Yes
32	TLR2	TLR2 Entrez,  Source	toll-like receptor 2	1778	0.188	0.4026	Yes
33	BIRC3	BIRC3 Entrez,  Source	baculoviral IAP repeat-containing 3	1781	0.188	0.4124	Yes
34	POLR3B	POLR3B Entrez,  Source	polymerase (RNA) III (DNA directed) polypeptide B	1826	0.186	0.4201	Yes
35	CLEC4E	CLEC4E Entrez,  Source	C-type lectin domain family 4, member E	1888	0.184	0.4269	Yes
36	CARD11	CARD11 Entrez,  Source	caspase recruitment domain family, member 11	1907	0.184	0.4358	Yes
37	TXK	TXK Entrez,  Source	TXK tyrosine kinase	1965	0.181	0.4426	Yes
38	TLR1	TLR1 Entrez,  Source	toll-like receptor 1	1968	0.181	0.4520	Yes
39	CD226	CD226 Entrez,  Source	CD226 molecule	2121	0.175	0.4540	Yes
40	RIPK2	RIPK2 Entrez,  Source	receptor-interacting serine-threonine kinase 2	2184	0.173	0.4602	Yes
41	TNFAIP3	TNFAIP3 Entrez,  Source	tumor necrosis factor, alpha-induced protein 3	2212	0.172	0.4679	Yes
42	CD14	CD14 Entrez,  Source	CD14 molecule	2213	0.172	0.4770	Yes
43	COLEC12	COLEC12 Entrez,  Source	collectin sub-family member 12	2404	0.166	0.4767	Yes
44	TIRAP	TIRAP Entrez,  Source	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	2521	0.163	0.4798	Yes
45	TLR5	TLR5 Entrez,  Source	toll-like receptor 5	2606	0.160	0.4842	Yes
46	LY96	LY96 Entrez,  Source	lymphocyte antigen 96	2680	0.158	0.4890	Yes
47	GBP5	GBP5 Entrez,  Source	guanylate binding protein 5	2757	0.156	0.4936	Yes
48	PAK3	PAK3 Entrez,  Source	p21 (CDKN1A)-activated kinase 3	2934	0.151	0.4932	Yes
49	TRIL			3161	0.145	0.4900	Yes
50	CTSS	CTSS Entrez,  Source	cathepsin S	3174	0.145	0.4971	Yes
51	ICAM3	ICAM3 Entrez,  Source	intercellular adhesion molecule 3	3489	0.137	0.4893	Yes
52	KLRK1	KLRK1 Entrez,  Source	killer cell lectin-like receptor subfamily K, member 1	3793	0.130	0.4817	Yes
53	ADAM8	ADAM8 Entrez,  Source	ADAM metallopeptidase domain 8	4010	0.124	0.4779	Yes
54	WNT5A	WNT5A Entrez,  Source	wingless-type MMTV integration site family, member 5A	4018	0.124	0.4841	Yes
55	SH2D1B	SH2D1B Entrez,  Source	SH2 domain containing 1B	4147	0.121	0.4844	Yes
56	LYN	LYN Entrez,  Source	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	4186	0.120	0.4889	Yes
57	TRAF3	TRAF3 Entrez,  Source	TNF receptor-associated factor 3	4211	0.120	0.4941	Yes
58	RELB	RELB Entrez,  Source	v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian)	4244	0.119	0.4988	Yes
59	SH2D1A	SH2D1A Entrez,  Source	SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)	4253	0.119	0.5047	Yes
60	LAG3	LAG3 Entrez,  Source	lymphocyte-activation gene 3	5183	0.099	0.4655	No
61	PSMD7	PSMD7 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)	6054	0.084	0.4284	No
62	PSMB10	PSMB10 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 10	6246	0.080	0.4235	No
63	LGALS9	LGALS9 Entrez,  Source	lectin, galactoside-binding, soluble, 9 (galectin 9)	6379	0.078	0.4213	No
64	S100A14	S100A14 Entrez,  Source	S100 calcium binding protein A14	6451	0.077	0.4220	No
65	CRTAM	CRTAM Entrez,  Source	cytotoxic and regulatory T cell molecule	6460	0.077	0.4256	No
66	TLR3	TLR3 Entrez,  Source	toll-like receptor 3	6628	0.074	0.4215	No
67	UBE2V1	UBE2V1 Entrez,  Source	ubiquitin-conjugating enzyme E2 variant 1	6751	0.071	0.4195	No
68	AIM2	AIM2 Entrez,  Source	absent in melanoma 2	6999	0.068	0.4112	No
69	MMP2	MMP2 Entrez,  Source	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	7089	0.066	0.4105	No
70	PVR	PVR Entrez,  Source	poliovirus receptor	7170	0.065	0.4101	No
71	KRAS	KRAS Entrez,  Source	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	7196	0.064	0.4123	No
72	IRAK2	IRAK2 Entrez,  Source	interleukin-1 receptor-associated kinase 2	7265	0.063	0.4124	No
73	PSMC1	PSMC1 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, ATPase, 1	7476	0.060	0.4055	No
74	PSME4	PSME4 Entrez,  Source	proteasome (prosome, macropain) activator subunit 4	7684	0.057	0.3986	No
75	PSMD1	PSMD1 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	7714	0.056	0.4002	No
76	UBE2D1	UBE2D1 Entrez,  Source	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	7960	0.052	0.3912	No
77	PSMA2	PSMA2 Entrez,  Source	proteasome (prosome, macropain) subunit, alpha type, 2	7977	0.052	0.3932	No
78	IL12A	IL12A Entrez,  Source	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	8073	0.051	0.3914	No
79	POLR3D	POLR3D Entrez,  Source	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	8096	0.050	0.3930	No
80	CTSB	CTSB Entrez,  Source	cathepsin B	8199	0.049	0.3907	No
81	NRAS	NRAS Entrez,  Source	neuroblastoma RAS viral (v-ras) oncogene homolog	8260	0.048	0.3903	No
82	FYN	FYN Entrez,  Source	FYN oncogene related to SRC, FGR, YES	8363	0.046	0.3879	No
83	NOD1			8480	0.045	0.3847	No
84	MYD88	MYD88 Entrez,  Source	myeloid differentiation primary response gene (88)	8547	0.044	0.3839	No
85	HSPD1	HSPD1 Entrez,  Source	heat shock 60kDa protein 1 (chaperonin)	8556	0.044	0.3858	No
86	CCL5	CCL5 Entrez,  Source	chemokine (C-C motif) ligand 5	8905	0.039	0.3712	No
87	ITCH	ITCH Entrez,  Source	itchy homolog E3 ubiquitin protein ligase (mouse)	9161	0.036	0.3609	No
88	CTSK	CTSK Entrez,  Source	cathepsin K (pycnodysostosis)	9272	0.034	0.3574	No
89	IRAK1	IRAK1 Entrez,  Source	interleukin-1 receptor-associated kinase 1	9314	0.034	0.3572	No
90	SRC	SRC Entrez,  Source	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	9410	0.033	0.3544	No
91	HPX	HPX Entrez,  Source	hemopexin	9428	0.032	0.3553	No
92	HSP90B1	HSP90B1 Entrez,  Source	heat shock protein 90kDa beta (Grp94), member 1	9474	0.032	0.3548	No
93	CNPY3			9531	0.031	0.3538	No
94	IFI16	IFI16 Entrez,  Source	interferon, gamma-inducible protein 16	9719	0.029	0.3464	No
95	PSMB7	PSMB7 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 7	9771	0.028	0.3454	No
96	TNIP1	TNIP1 Entrez,  Source	TNFAIP3 interacting protein 1	10197	0.024	0.3264	No
97	PSMB5	PSMB5 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 5	10238	0.024	0.3257	No
98	DMBT1	DMBT1 Entrez,  Source	deleted in malignant brain tumors 1	10284	0.023	0.3248	No
99	PIK3R4	PIK3R4 Entrez,  Source	phosphoinositide-3-kinase, regulatory subunit 4, p150	10298	0.023	0.3254	No
100	PRKACB	PRKACB Entrez,  Source	protein kinase, cAMP-dependent, catalytic, beta	10312	0.023	0.3260	No
101	PRKCE	PRKCE Entrez,  Source	protein kinase C, epsilon	10363	0.022	0.3247	No
102	NLRC5			10403	0.022	0.3240	No
103	PAK1	PAK1 Entrez,  Source	p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)	10439	0.022	0.3235	No
104	TLR4	TLR4 Entrez,  Source	toll-like receptor 4	10488	0.021	0.3223	No
105	BIRC2	BIRC2 Entrez,  Source	baculoviral IAP repeat-containing 2	10505	0.021	0.3226	No
106	RPS6KA3	RPS6KA3 Entrez,  Source	ribosomal protein S6 kinase, 90kDa, polypeptide 3	10604	0.020	0.3190	No
107	PAK2	PAK2 Entrez,  Source	p21 (CDKN1A)-activated kinase 2	10640	0.020	0.3184	No
108	MAP3K1	MAP3K1 Entrez,  Source	mitogen-activated protein kinase kinase kinase 1	10662	0.019	0.3184	No
109	TAB2			10793	0.018	0.3131	No
110	UNC93B1	UNC93B1 Entrez,  Source	unc-93 homolog B1 (C. elegans)	10829	0.018	0.3124	No
111	CASP8	CASP8 Entrez,  Source	caspase 8, apoptosis-related cysteine peptidase	10927	0.017	0.3087	No
112	PLCG2	PLCG2 Entrez,  Source	phospholipase C, gamma 2 (phosphatidylinositol-specific)	11182	0.015	0.2973	No
113	LAMP1	LAMP1 Entrez,  Source	lysosomal-associated membrane protein 1	11257	0.014	0.2945	No
114	MAPKAPK2	MAPKAPK2 Entrez,  Source	mitogen-activated protein kinase-activated protein kinase 2	11342	0.013	0.2912	No
115	PSMD11	PSMD11 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	11394	0.013	0.2894	No
116	EP300	EP300 Entrez,  Source	E1A binding protein p300	11472	0.012	0.2863	No
117	UBE2K			11589	0.011	0.2813	No
118	MB21D1			11683	0.010	0.2774	No
119	MED1			11860	0.008	0.2694	No
120	AP1G1	AP1G1 Entrez,  Source	adaptor-related protein complex 1, gamma 1 subunit	11927	0.007	0.2667	No
121	NFKB1	NFKB1 Entrez,  Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	11961	0.007	0.2655	No
122	PSMB2	PSMB2 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 2	12246	0.005	0.2522	No
123	RPS19	RPS19 Entrez,  Source	ribosomal protein S19	12273	0.004	0.2511	No
124	TICAM1	TICAM1 Entrez,  Source	toll-like receptor adaptor molecule 1	12381	0.003	0.2462	No
125	PSMD14	PSMD14 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	12438	0.003	0.2437	No
126	CYLD	CYLD Entrez,  Source	cylindromatosis (turban tumor syndrome)	12442	0.003	0.2437	No
127	PSMC2	PSMC2 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, ATPase, 2	12496	0.003	0.2413	No
128	MAVS			12529	0.002	0.2399	No
129	FBXW11	FBXW11 Entrez,  Source	F-box and WD-40 domain protein 11	12575	0.002	0.2379	No
130	TBK1	TBK1 Entrez,  Source	TANK-binding kinase 1	12578	0.002	0.2379	No
131	CREBBP	CREBBP Entrez,  Source	CREB binding protein (Rubinstein-Taybi syndrome)	12588	0.002	0.2375	No
132	TANK	TANK Entrez,  Source	TRAF family member-associated NFKB activator	12591	0.002	0.2375	No
133	PSMD10	PSMD10 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	12635	0.001	0.2355	No
134	UBC	UBC Entrez,  Source	ubiquitin C	12666	0.001	0.2342	No
135	PSME3	PSME3 Entrez,  Source	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	12757	0.000	0.2299	No
136	PSMD6	PSMD6 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	12776	0.000	0.2290	No
137	STAT5B	STAT5B Entrez,  Source	signal transducer and activator of transcription 5B	12809	-0.000	0.2275	No
138	PSMD12	PSMD12 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	12816	-0.000	0.2272	No
139	TRIM5	TRIM5 Entrez,  Source	tripartite motif-containing 5	12876	-0.001	0.2244	No
140	IFIH1	IFIH1 Entrez,  Source	interferon induced with helicase C domain 1	12971	-0.001	0.2200	No
141	PYCARD	PYCARD Entrez,  Source	PYD and CARD domain containing	13204	-0.003	0.2091	No
142	PSMA6	PSMA6 Entrez,  Source	proteasome (prosome, macropain) subunit, alpha type, 6	13219	-0.004	0.2086	No
143	MALT1	MALT1 Entrez,  Source	mucosa associated lymphoid tissue lymphoma translocation gene 1	13263	-0.004	0.2068	No
144	PSMD2	PSMD2 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	13293	-0.004	0.2056	No
145	LSM14A	LSM14A Entrez,  Source	LSM14 homolog A (SCD6, S. cerevisiae)	13375	-0.005	0.2020	No
146	TRAF6	TRAF6 Entrez,  Source	TNF receptor-associated factor 6	13413	-0.005	0.2005	No
147	CUL1	CUL1 Entrez,  Source	cullin 1	13641	-0.007	0.1900	No
148	CHUK	CHUK Entrez,  Source	conserved helix-loop-helix ubiquitous kinase	13754	-0.008	0.1851	No
149	PSMD5	PSMD5 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	13805	-0.009	0.1832	No
150	NFKBIA	NFKBIA Entrez,  Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	13819	-0.009	0.1831	No
151	PSMB3	PSMB3 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 3	13827	-0.009	0.1832	No
152	PIK3C3	PIK3C3 Entrez,  Source	phosphoinositide-3-kinase, class 3	13944	-0.010	0.1782	No
153	CADM1			14041	-0.011	0.1742	No
154	PSMC6	PSMC6 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, ATPase, 6	14293	-0.013	0.1628	No
155	CD36	CD36 Entrez,  Source	CD36 molecule (thrombospondin receptor)	14295	-0.013	0.1635	No
156	RFTN1	RFTN1 Entrez,  Source	raftlin, lipid raft linker 1	14305	-0.013	0.1637	No
157	PSMD4	PSMD4 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	14364	-0.013	0.1617	No
158	UBE2D3	UBE2D3 Entrez,  Source	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	14465	-0.014	0.1576	No
159	PRKCD	PRKCD Entrez,  Source	protein kinase C, delta	14536	-0.015	0.1551	No
160	UBE2D2	UBE2D2 Entrez,  Source	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	14677	-0.016	0.1492	No
161	IRF3	IRF3 Entrez,  Source	interferon regulatory factor 3	14709	-0.016	0.1486	No
162	PSMA5	PSMA5 Entrez,  Source	proteasome (prosome, macropain) subunit, alpha type, 5	14758	-0.017	0.1472	No
163	SIN3A	SIN3A Entrez,  Source	SIN3 homolog A, transcription regulator (yeast)	14919	-0.018	0.1405	No
164	PSME2	PSME2 Entrez,  Source	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	14955	-0.018	0.1398	No
165	POLR3C	POLR3C Entrez,  Source	polymerase (RNA) III (DNA directed) polypeptide C (62kD)	15009	-0.019	0.1383	No
166	UBA52	UBA52 Entrez,  Source	ubiquitin A-52 residue ribosomal protein fusion product 1	15098	-0.020	0.1351	No
167	PSMD13	PSMD13 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	15101	-0.020	0.1360	No
168	PSMB8	PSMB8 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	15266	-0.021	0.1293	No
169	RIPK1	RIPK1 Entrez,  Source	receptor (TNFRSF)-interacting serine-threonine kinase 1	15282	-0.021	0.1297	No
170	TAB1			15285	-0.021	0.1307	No
171	IKBKB	IKBKB Entrez,  Source	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	15314	-0.022	0.1305	No
172	PSMC4	PSMC4 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, ATPase, 4	15335	-0.022	0.1307	No
173	RAF1	RAF1 Entrez,  Source	v-raf-1 murine leukemia viral oncogene homolog 1	15362	-0.022	0.1306	No
174	MAP3K7	MAP3K7 Entrez,  Source	mitogen-activated protein kinase kinase kinase 7	15371	-0.022	0.1314	No
175	PSMA4	PSMA4 Entrez,  Source	proteasome (prosome, macropain) subunit, alpha type, 4	15481	-0.023	0.1274	No
176	PSMB4	PSMB4 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 4	15527	-0.023	0.1265	No
177	PRKACA	PRKACA Entrez,  Source	protein kinase, cAMP-dependent, catalytic, alpha	15636	-0.024	0.1226	No
178	PSMC3	PSMC3 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, ATPase, 3	15766	-0.025	0.1178	No
179	TAB3			15818	-0.026	0.1167	No
180	IRF7	IRF7 Entrez,  Source	interferon regulatory factor 7	15840	-0.026	0.1171	No
181	PSMD3	PSMD3 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	15893	-0.027	0.1160	No
182	UBB	UBB Entrez,  Source	ubiquitin B	15940	-0.027	0.1153	No
183	PSMA3	PSMA3 Entrez,  Source	proteasome (prosome, macropain) subunit, alpha type, 3	15947	-0.027	0.1164	No
184	PSMB1	PSMB1 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 1	16242	-0.030	0.1040	No
185	UBE2N	UBE2N Entrez,  Source	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	16312	-0.031	0.1023	No
186	TMEM173	TMEM173 Entrez,  Source	transmembrane protein 173	16386	-0.031	0.1005	No
187	PSMD8	PSMD8 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	16395	-0.032	0.1017	No
188	PSMF1	PSMF1 Entrez,  Source	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	16453	-0.032	0.1007	No
189	PSMA7	PSMA7 Entrez,  Source	proteasome (prosome, macropain) subunit, alpha type, 7	16484	-0.032	0.1010	No
190	PSMB6	PSMB6 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 6	16495	-0.032	0.1022	No
191	RPS27A	RPS27A Entrez,  Source	ribosomal protein S27a	16508	-0.032	0.1034	No
192	RELA	RELA Entrez,  Source	v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)	16661	-0.034	0.0979	No
193	BTRC	BTRC Entrez,  Source	beta-transducin repeat containing	16693	-0.034	0.0982	No
194	POLR3G	POLR3G Entrez,  Source	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	16794	-0.036	0.0953	No
195	HMGB1	HMGB1 Entrez,  Source	high-mobility group box 1	17008	-0.038	0.0871	No
196	DDX58	DDX58 Entrez,  Source	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	17183	-0.040	0.0809	No
197	NCR3	NCR3 Entrez,  Source	natural cytotoxicity triggering receptor 3	17362	-0.042	0.0746	No
198	MAPKAPK3	MAPKAPK3 Entrez,  Source	mitogen-activated protein kinase-activated protein kinase 3	17392	-0.042	0.0755	No
199	SKP1			17457	-0.043	0.0747	No
200	PSME1	PSME1 Entrez,  Source	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	17553	-0.045	0.0725	No
201	IRAK4	IRAK4 Entrez,  Source	interleukin-1 receptor-associated kinase 4	17589	-0.045	0.0732	No
202	PDPK1	PDPK1 Entrez,  Source	3-phosphoinositide dependent protein kinase-1	17787	-0.048	0.0663	No
203	RPS6KA5	RPS6KA5 Entrez,  Source	ribosomal protein S6 kinase, 90kDa, polypeptide 5	17876	-0.049	0.0647	No
204	PSMC5	PSMC5 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, ATPase, 5	17886	-0.049	0.0669	No
205	FFAR2	FFAR2 Entrez,  Source	free fatty acid receptor 2	18328	-0.056	0.0488	No
206	POLR3F	POLR3F Entrez,  Source	polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa	18467	-0.059	0.0453	No
207	HLA-E	HLA-E Entrez,  Source	major histocompatibility complex, class I, E	18485	-0.059	0.0476	No
208	HMGB2	HMGB2 Entrez,  Source	high-mobility group box 2	18526	-0.060	0.0489	No
209	PGLYRP2	PGLYRP2 Entrez,  Source	peptidoglycan recognition protein 2	18583	-0.061	0.0494	No
210	TNIP2	TNIP2 Entrez,  Source	TNFAIP3 interacting protein 2	18649	-0.063	0.0496	No
211	HRAS	HRAS Entrez,  Source	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	18923	-0.069	0.0402	No
212	PLSCR1	PLSCR1 Entrez,  Source	phospholipid scramblase 1	18940	-0.069	0.0431	No
213	ICAM2	ICAM2 Entrez,  Source	intercellular adhesion molecule 2	19340	-0.081	0.0283	No
214	PSMA1	PSMA1 Entrez,  Source	proteasome (prosome, macropain) subunit, alpha type, 1	19344	-0.081	0.0324	No
215	PSMB9	PSMB9 Entrez,  Source	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	19621	-0.091	0.0241	No
216	PSMD9	PSMD9 Entrez,  Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	19651	-0.092	0.0275	No
217	MAP2K6	MAP2K6 Entrez,  Source	mitogen-activated protein kinase kinase 6	20166	-0.116	0.0091	No
218	IKBKG	IKBKG Entrez,  Source	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	20251	-0.120	0.0114	No
219	IRAK3	IRAK3 Entrez,  Source	interleukin-1 receptor-associated kinase 3	20304	-0.124	0.0154	No
220	BCL10	BCL10 Entrez,  Source	B-cell CLL/lymphoma 10	20313	-0.124	0.0216	No
221	TRIM6	TRIM6 Entrez,  Source	tripartite motif-containing 6	20525	-0.142	0.0190	No
222	FADD	FADD Entrez,  Source	Fas (TNFRSF6)-associated via death domain	20913	-0.199	0.0110	No

Fig 2: GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE: Random ES distribution   
Gene set null distribution of ES for GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE