Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 1 |
| GeneSet | GO_POSITIVE_REGULATION_OF_INTERFERON_BETA_PRODUCTION |
| Enrichment Score (ES) | 0.572435 |
| Normalized Enrichment Score (NES) | 2.1017773 |
| Nominal p-value | 0.0019493178 |
| FDR q-value | 0.21467347 |
| FWER p-Value | 0.308 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TLR8 | TLR8 Entrez, Source | toll-like receptor 8 | 144 | 0.346 | 0.1518 | Yes |
| 2 | TLR7 | TLR7 Entrez, Source | toll-like receptor 7 | 292 | 0.306 | 0.2852 | Yes |
| 3 | IRF5 | IRF5 Entrez, Source | interferon regulatory factor 5 | 482 | 0.275 | 0.4022 | Yes |
| 4 | TLR2 | TLR2 Entrez, Source | toll-like receptor 2 | 1778 | 0.188 | 0.4271 | Yes |
| 5 | POLR3B | POLR3B Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide B | 1826 | 0.186 | 0.5103 | Yes |
| 6 | RIPK2 | RIPK2 Entrez, Source | receptor-interacting serine-threonine kinase 2 | 2184 | 0.173 | 0.5724 | Yes |
| 7 | ZBTB20 | ZBTB20 Entrez, Source | zinc finger and BTB domain containing 20 | 3764 | 0.130 | 0.5574 | No |
| 8 | TLR3 | TLR3 Entrez, Source | toll-like receptor 3 | 6628 | 0.074 | 0.4556 | No |
| 9 | POLR3D | POLR3D Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa | 8096 | 0.050 | 0.4093 | No |
| 10 | POLR3A | POLR3A Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide A, 155kDa | 9188 | 0.035 | 0.3737 | No |
| 11 | IFNAR1 | IFNAR1 Entrez, Source | interferon (alpha, beta and omega) receptor 1 | 10243 | 0.024 | 0.3346 | No |
| 12 | TLR4 | TLR4 Entrez, Source | toll-like receptor 4 | 10488 | 0.021 | 0.3326 | No |
| 13 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 11218 | 0.014 | 0.3047 | No |
| 14 | TICAM1 | TICAM1 Entrez, Source | toll-like receptor adaptor molecule 1 | 12381 | 0.003 | 0.2512 | No |
| 15 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 12427 | 0.003 | 0.2505 | No |
| 16 | MAVS | 12529 | 0.002 | 0.2468 | No | ||
| 17 | TBK1 | TBK1 Entrez, Source | TANK-binding kinase 1 | 12578 | 0.002 | 0.2453 | No |
| 18 | IFIH1 | IFIH1 Entrez, Source | interferon induced with helicase C domain 1 | 12971 | -0.001 | 0.2274 | No |
| 19 | ZC3HAV1 | ZC3HAV1 Entrez, Source | zinc finger CCCH-type, antiviral 1 | 14396 | -0.014 | 0.1663 | No |
| 20 | RNF135 | RNF135 Entrez, Source | ring finger protein 135 | 14612 | -0.015 | 0.1632 | No |
| 21 | IRF3 | IRF3 Entrez, Source | interferon regulatory factor 3 | 14709 | -0.016 | 0.1661 | No |
| 22 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 15009 | -0.019 | 0.1605 | No |
| 23 | FLOT1 | FLOT1 Entrez, Source | flotillin 1 | 15663 | -0.025 | 0.1409 | No |
| 24 | IRF7 | IRF7 Entrez, Source | interferon regulatory factor 7 | 15840 | -0.026 | 0.1445 | No |
| 25 | POLR3G | POLR3G Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | 16794 | -0.036 | 0.1157 | No |
| 26 | HMGB1 | HMGB1 Entrez, Source | high-mobility group box 1 | 17008 | -0.038 | 0.1229 | No |
| 27 | DDX58 | DDX58 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 17183 | -0.040 | 0.1329 | No |
| 28 | POLR3F | POLR3F Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa | 18467 | -0.059 | 0.0991 | No |
| 29 | HMGB2 | HMGB2 Entrez, Source | high-mobility group box 2 | 18526 | -0.060 | 0.1240 | No |
