Details for gene set GO_REGULATION_OF_INNATE_IMMUNE

Table: GSEA Results Summary

Dataset	NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos
Phenotype	NOV0093.cls#obese_versus_normal_repos
Upregulated in class	1
GeneSet	GO_REGULATION_OF_INNATE_IMMUNE_RESPONSE
Enrichment Score (ES)	0.45006356
Normalized Enrichment Score (NES)	2.0956337
Nominal p-value	0.0019455253
FDR q-value	0.19977477
FWER p-Value	0.328

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ITGAM	ITGAM Entrez, Source	integrin, alpha M (complement component 3 receptor 3 subunit)	13	0.442	0.0171	Yes
2	CR1	CR1 Entrez, Source	complement component (3b/4b) receptor 1 (Knops blood group)	20	0.420	0.0337	Yes
3	PIK3AP1	PIK3AP1 Entrez, Source	phosphoinositide-3-kinase adaptor protein 1	25	0.416	0.0502	Yes
4	BTK	BTK Entrez, Source	Bruton agammaglobulinemia tyrosine kinase	28	0.412	0.0667	Yes
5	VAV1	VAV1 Entrez, Source	vav 1 oncogene	32	0.405	0.0828	Yes
6	CD86	CD86 Entrez, Source	CD86 molecule	41	0.398	0.0984	Yes
7	LILRB1	LILRB1 Entrez, Source	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	48	0.393	0.1139	Yes
8	NLRC4			78	0.376	0.1276	Yes
9	TLR6	TLR6 Entrez, Source	toll-like receptor 6	104	0.365	0.1410	Yes
10	CD209	CD209 Entrez, Source	CD209 molecule	110	0.362	0.1553	Yes
11	TLR8	TLR8 Entrez, Source	toll-like receptor 8	144	0.346	0.1676	Yes
12	CLEC7A	CLEC7A Entrez, Source	C-type lectin domain family 7, member A	171	0.336	0.1799	Yes
13	USP18	USP18 Entrez, Source	ubiquitin specific peptidase 18	269	0.311	0.1877	Yes
14	MARCO	MARCO Entrez, Source	macrophage receptor with collagenous structure	276	0.309	0.1998	Yes
15	TLR7	TLR7 Entrez, Source	toll-like receptor 7	292	0.306	0.2114	Yes
16	EREG	EREG Entrez, Source	epiregulin	294	0.306	0.2237	Yes
17	HCK	HCK Entrez, Source	hemopoietic cell kinase	300	0.306	0.2357	Yes
18	LBP	LBP Entrez, Source	lipopolysaccharide binding protein	391	0.290	0.2431	Yes
19	IRF4	IRF4 Entrez, Source	interferon regulatory factor 4	408	0.288	0.2539	Yes
20	FCER1G	FCER1G Entrez, Source	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	421	0.286	0.2648	Yes
21	ITGB2	ITGB2 Entrez, Source	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	433	0.284	0.2757	Yes
22	HAVCR2	HAVCR2 Entrez, Source	hepatitis A virus cellular receptor 2	463	0.279	0.2855	Yes
23	PIK3R6			687	0.253	0.2849	Yes
24	NOD2			948	0.232	0.2818	Yes
25	FCN1	FCN1 Entrez, Source	ficolin (collagen/fibrinogen domain containing) 1	1006	0.228	0.2882	Yes
26	CD180	CD180 Entrez, Source	CD180 molecule	1012	0.228	0.2971	Yes
27	IKBKE	IKBKE Entrez, Source	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	1083	0.223	0.3027	Yes
28	SCARA3	SCARA3 Entrez, Source	scavenger receptor class A, member 3	1106	0.222	0.3105	Yes
29	TLR10	TLR10 Entrez, Source	toll-like receptor 10	1131	0.220	0.3182	Yes
30	SLAMF6	SLAMF6 Entrez, Source	SLAM family member 6	1150	0.219	0.3261	Yes
31	CD1D	CD1D Entrez, Source	CD1d molecule	1158	0.218	0.3345	Yes
32	LGMN	LGMN Entrez, Source	legumain	1335	0.209	0.3344	Yes
33	COCH	COCH Entrez, Source	coagulation factor C homolog, cochlin (Limulus polyphemus)	1372	0.206	0.3410	Yes
34	RASGRP1	RASGRP1 Entrez, Source	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	1470	0.201	0.3444	Yes
35	CARD9	CARD9 Entrez, Source	caspase recruitment domain family, member 9	1535	0.199	0.3493	Yes
36	SYK	SYK Entrez, Source	spleen tyrosine kinase	1640	0.194	0.3521	Yes
37	TLR2	TLR2 Entrez, Source	toll-like receptor 2	1778	0.188	0.3531	Yes
38	BIRC3	BIRC3 Entrez, Source	baculoviral IAP repeat-containing 3	1781	0.188	0.3605	Yes
39	POLR3B	POLR3B Entrez, Source	polymerase (RNA) III (DNA directed) polypeptide B	1826	0.186	0.3659	Yes
40	CLEC4E	CLEC4E Entrez, Source	C-type lectin domain family 4, member E	1888	0.184	0.3704	Yes
41	CARD11	CARD11 Entrez, Source	caspase recruitment domain family, member 11	1907	0.184	0.3769	Yes
42	TXK	TXK Entrez, Source	TXK tyrosine kinase	1965	0.181	0.3814	Yes
43	TLR1	TLR1 Entrez, Source	toll-like receptor 1	1968	0.181	0.3886	Yes
44	FGR	FGR Entrez, Source	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	2034	0.178	0.3926	Yes
45	SMPDL3B	SMPDL3B Entrez, Source	sphingomyelin phosphodiesterase, acid-like 3B	2070	0.177	0.3980	Yes
46	CD226	CD226 Entrez, Source	CD226 molecule	2121	0.175	0.4026	Yes
47	RIPK2	RIPK2 Entrez, Source	receptor-interacting serine-threonine kinase 2	2184	0.173	0.4066	Yes
48	TNFAIP3	TNFAIP3 Entrez, Source	tumor necrosis factor, alpha-induced protein 3	2212	0.172	0.4122	Yes
49	CD14	CD14 Entrez, Source	CD14 molecule	2213	0.172	0.4191	Yes
50	COLEC12	COLEC12 Entrez, Source	collectin sub-family member 12	2404	0.166	0.4167	Yes
51	TIRAP	TIRAP Entrez, Source	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	2521	0.163	0.4176	Yes
52	TLR5	TLR5 Entrez, Source	toll-like receptor 5	2606	0.160	0.4200	Yes
53	LY96	LY96 Entrez, Source	lymphocyte antigen 96	2680	0.158	0.4229	Yes
54	GBP5	GBP5 Entrez, Source	guanylate binding protein 5	2757	0.156	0.4255	Yes
55	OTUD7A	OTUD7A Entrez, Source	OTU domain containing 7A	2881	0.153	0.4257	Yes
56	PAK3	PAK3 Entrez, Source	p21 (CDKN1A)-activated kinase 3	2934	0.151	0.4293	Yes
57	TRIL			3161	0.145	0.4242	Yes
58	CTSS	CTSS Entrez, Source	cathepsin S	3174	0.145	0.4295	Yes
59	PTPN22	PTPN22 Entrez, Source	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	3183	0.144	0.4349	Yes
60	ICAM3	ICAM3 Entrez, Source	intercellular adhesion molecule 3	3489	0.137	0.4258	Yes
61	KLRK1	KLRK1 Entrez, Source	killer cell lectin-like receptor subfamily K, member 1	3793	0.130	0.4164	Yes
62	GFI1	GFI1 Entrez, Source	growth factor independent 1	3797	0.130	0.4215	Yes
63	CYBA	CYBA Entrez, Source	cytochrome b-245, alpha polypeptide	3890	0.127	0.4222	Yes
64	IFNAR2	IFNAR2 Entrez, Source	interferon (alpha, beta and omega) receptor 2	3949	0.126	0.4244	Yes
65	ADAM8	ADAM8 Entrez, Source	ADAM metallopeptidase domain 8	4010	0.124	0.4265	Yes
66	WNT5A	WNT5A Entrez, Source	wingless-type MMTV integration site family, member 5A	4018	0.124	0.4312	Yes
67	PTPN6	PTPN6 Entrez, Source	protein tyrosine phosphatase, non-receptor type 6	4069	0.123	0.4337	Yes
68	SH2D1B	SH2D1B Entrez, Source	SH2 domain containing 1B	4147	0.121	0.4349	Yes
69	LYN	LYN Entrez, Source	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	4186	0.120	0.4379	Yes
70	TRAF3	TRAF3 Entrez, Source	TNF receptor-associated factor 3	4211	0.120	0.4415	Yes
71	RELB	RELB Entrez, Source	v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian)	4244	0.119	0.4447	Yes
72	SH2D1A	SH2D1A Entrez, Source	SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)	4253	0.119	0.4491	Yes
73	LEP	LEP Entrez, Source	leptin (obesity homolog, mouse)	4399	0.115	0.4468	Yes
74	SAMHD1	SAMHD1 Entrez, Source	SAM domain and HD domain 1	4428	0.115	0.4501	Yes
75	ARRB2	ARRB2 Entrez, Source	arrestin, beta 2	4621	0.111	0.4453	No
76	SARM1	SARM1 Entrez, Source	sterile alpha and TIR motif containing 1	4794	0.107	0.4413	No
77	SOCS1	SOCS1 Entrez, Source	suppressor of cytokine signaling 1	5004	0.103	0.4354	No
78	LAG3	LAG3 Entrez, Source	lymphocyte-activation gene 3	5183	0.099	0.4309	No
79	SOCS3	SOCS3 Entrez, Source	suppressor of cytokine signaling 3	5356	0.096	0.4265	No
80	F2RL1	F2RL1 Entrez, Source	coagulation factor II (thrombin) receptor-like 1	5377	0.096	0.4294	No
81	DUSP10	DUSP10 Entrez, Source	dual specificity phosphatase 10	5863	0.087	0.4096	No
82	ERAP1			6036	0.084	0.4047	No
83	PSMD7	PSMD7 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)	6054	0.084	0.4073	No
84	PELI1	PELI1 Entrez, Source	pellino homolog 1 (Drosophila)	6181	0.081	0.4045	No
85	PSMB10	PSMB10 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 10	6246	0.080	0.4046	No
86	NLRP6			6308	0.079	0.4049	No
87	LGALS9	LGALS9 Entrez, Source	lectin, galactoside-binding, soluble, 9 (galectin 9)	6379	0.078	0.4047	No
88	S100A14	S100A14 Entrez, Source	S100 calcium binding protein A14	6451	0.077	0.4044	No
89	DRD2	DRD2 Entrez, Source	dopamine receptor D2	6452	0.077	0.4075	No
90	CRTAM	CRTAM Entrez, Source	cytotoxic and regulatory T cell molecule	6460	0.077	0.4102	No
91	TLR3	TLR3 Entrez, Source	toll-like receptor 3	6628	0.074	0.4051	No
92	UBE2V1	UBE2V1 Entrez, Source	ubiquitin-conjugating enzyme E2 variant 1	6751	0.071	0.4022	No
93	HSPA1B	HSPA1B Entrez, Source	heat shock 70kDa protein 1B	6832	0.070	0.4011	No
94	HSPA1A	HSPA1A Entrez, Source	heat shock 70kDa protein 1A	6842	0.070	0.4035	No
95	AIM2	AIM2 Entrez, Source	absent in melanoma 2	6999	0.068	0.3987	No
96	PTPN11	PTPN11 Entrez, Source	protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)	7081	0.066	0.3975	No
97	MMP2	MMP2 Entrez, Source	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	7089	0.066	0.3998	No
98	SUSD4	SUSD4 Entrez, Source	sushi domain containing 4	7139	0.065	0.4001	No
99	PVR	PVR Entrez, Source	poliovirus receptor	7170	0.065	0.4013	No
100	KRAS	KRAS Entrez, Source	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	7196	0.064	0.4027	No
101	IRAK2	IRAK2 Entrez, Source	interleukin-1 receptor-associated kinase 2	7265	0.063	0.4019	No
102	PSMC1	PSMC1 Entrez, Source	proteasome (prosome, macropain) 26S subunit, ATPase, 1	7476	0.060	0.3943	No
103	PSME4	PSME4 Entrez, Source	proteasome (prosome, macropain) activator subunit 4	7684	0.057	0.3866	No
104	PSMD1	PSMD1 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	7714	0.056	0.3875	No
105	UBE2D1	UBE2D1 Entrez, Source	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	7960	0.052	0.3778	No
106	PSMA2	PSMA2 Entrez, Source	proteasome (prosome, macropain) subunit, alpha type, 2	7977	0.052	0.3791	No
107	IL12A	IL12A Entrez, Source	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	8073	0.051	0.3766	No
108	POLR3D	POLR3D Entrez, Source	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	8096	0.050	0.3776	No
109	CTSB	CTSB Entrez, Source	cathepsin B	8199	0.049	0.3746	No
110	NRAS	NRAS Entrez, Source	neuroblastoma RAS viral (v-ras) oncogene homolog	8260	0.048	0.3737	No
111	FYN	FYN Entrez, Source	FYN oncogene related to SRC, FGR, YES	8363	0.046	0.3707	No
112	TYRO3	TYRO3 Entrez, Source	TYRO3 protein tyrosine kinase	8376	0.046	0.3719	No
113	NOD1			8480	0.045	0.3688	No
114	NCR1	NCR1 Entrez, Source	natural cytotoxicity triggering receptor 1	8530	0.044	0.3682	No
115	MYD88	MYD88 Entrez, Source	myeloid differentiation primary response gene (88)	8547	0.044	0.3692	No
116	HSPD1	HSPD1 Entrez, Source	heat shock 60kDa protein 1 (chaperonin)	8556	0.044	0.3706	No
117	STAT1	STAT1 Entrez, Source	signal transducer and activator of transcription 1, 91kDa	8620	0.043	0.3692	No
118	BPIFB1			8639	0.042	0.3701	No
119	CCL5	CCL5 Entrez, Source	chemokine (C-C motif) ligand 5	8905	0.039	0.3589	No
120	ANKRD17	ANKRD17 Entrez, Source	ankyrin repeat domain 17	8936	0.038	0.3590	No
121	NLRX1			9128	0.036	0.3513	No
122	ITCH	ITCH Entrez, Source	itchy homolog E3 ubiquitin protein ligase (mouse)	9161	0.036	0.3512	No
123	CTSK	CTSK Entrez, Source	cathepsin K (pycnodysostosis)	9272	0.034	0.3473	No
124	IRAK1	IRAK1 Entrez, Source	interleukin-1 receptor-associated kinase 1	9314	0.034	0.3467	No
125	SRC	SRC Entrez, Source	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	9410	0.033	0.3434	No
126	HPX	HPX Entrez, Source	hemopexin	9428	0.032	0.3439	No
127	HSP90B1	HSP90B1 Entrez, Source	heat shock protein 90kDa beta (Grp94), member 1	9474	0.032	0.3430	No
128	RSAD2	RSAD2 Entrez, Source	radical S-adenosyl methionine domain containing 2	9479	0.032	0.3441	No
129	CNPY3			9531	0.031	0.3429	No
130	JAK2	JAK2 Entrez, Source	Janus kinase 2 (a protein tyrosine kinase)	9605	0.030	0.3406	No
131	IFI16	IFI16 Entrez, Source	interferon, gamma-inducible protein 16	9719	0.029	0.3363	No
132	PSMB7	PSMB7 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 7	9771	0.028	0.3350	No
133	TYK2	TYK2 Entrez, Source	tyrosine kinase 2	9943	0.027	0.3279	No
134	PIAS1	PIAS1 Entrez, Source	protein inhibitor of activated STAT, 1	9988	0.026	0.3268	No
135	TNIP1	TNIP1 Entrez, Source	TNFAIP3 interacting protein 1	10197	0.024	0.3178	No
136	PSMB5	PSMB5 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 5	10238	0.024	0.3168	No
137	IFNAR1	IFNAR1 Entrez, Source	interferon (alpha, beta and omega) receptor 1	10243	0.024	0.3176	No
138	UBQLN1	UBQLN1 Entrez, Source	ubiquilin 1	10271	0.023	0.3172	No
139	DMBT1	DMBT1 Entrez, Source	deleted in malignant brain tumors 1	10284	0.023	0.3176	No
140	PIK3R4	PIK3R4 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 4, p150	10298	0.023	0.3178	No
141	PRKACB	PRKACB Entrez, Source	protein kinase, cAMP-dependent, catalytic, beta	10312	0.023	0.3181	No
142	PRKCE	PRKCE Entrez, Source	protein kinase C, epsilon	10363	0.022	0.3166	No
143	NLRC5			10403	0.022	0.3156	No
144	PAK1	PAK1 Entrez, Source	p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)	10439	0.022	0.3148	No
145	TLR4	TLR4 Entrez, Source	toll-like receptor 4	10488	0.021	0.3134	No
146	BIRC2	BIRC2 Entrez, Source	baculoviral IAP repeat-containing 2	10505	0.021	0.3134	No
147	RPS6KA3	RPS6KA3 Entrez, Source	ribosomal protein S6 kinase, 90kDa, polypeptide 3	10604	0.020	0.3095	No
148	PAK2	PAK2 Entrez, Source	p21 (CDKN1A)-activated kinase 2	10640	0.020	0.3086	No
149	MAP3K1	MAP3K1 Entrez, Source	mitogen-activated protein kinase kinase kinase 1	10662	0.019	0.3084	No
150	TAB2			10793	0.018	0.3029	No
151	UNC93B1	UNC93B1 Entrez, Source	unc-93 homolog B1 (C. elegans)	10829	0.018	0.3019	No
152	CASP8	CASP8 Entrez, Source	caspase 8, apoptosis-related cysteine peptidase	10927	0.017	0.2979	No
153	PLCG2	PLCG2 Entrez, Source	phospholipase C, gamma 2 (phosphatidylinositol-specific)	11182	0.015	0.2863	No
154	IRF1	IRF1 Entrez, Source	interferon regulatory factor 1	11218	0.014	0.2852	No
155	LAMP1	LAMP1 Entrez, Source	lysosomal-associated membrane protein 1	11257	0.014	0.2840	No
156	MAPKAPK2	MAPKAPK2 Entrez, Source	mitogen-activated protein kinase-activated protein kinase 2	11342	0.013	0.2805	No
157	PSMD11	PSMD11 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	11394	0.013	0.2785	No
158	EP300	EP300 Entrez, Source	E1A binding protein p300	11472	0.012	0.2753	No
159	CAV1	CAV1 Entrez, Source	caveolin 1, caveolae protein, 22kDa	11494	0.011	0.2748	No
160	WDFY1	WDFY1 Entrez, Source	WD repeat and FYVE domain containing 1	11573	0.011	0.2715	No
161	UBE2K			11589	0.011	0.2712	No
162	MB21D1			11683	0.010	0.2671	No
163	MED1			11860	0.008	0.2590	No
164	JAK1	JAK1 Entrez, Source	Janus kinase 1 (a protein tyrosine kinase)	11892	0.008	0.2578	No
165	AP1G1	AP1G1 Entrez, Source	adaptor-related protein complex 1, gamma 1 subunit	11927	0.007	0.2565	No
166	PTPN2	PTPN2 Entrez, Source	protein tyrosine phosphatase, non-receptor type 2	11947	0.007	0.2559	No
167	NFKB1	NFKB1 Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	11961	0.007	0.2555	No
168	HSP90AB1	HSP90AB1 Entrez, Source	heat shock protein 90kDa alpha (cytosolic), class B member 1	12158	0.005	0.2463	No
169	PSMB2	PSMB2 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 2	12246	0.005	0.2423	No
170	RPS19	RPS19 Entrez, Source	ribosomal protein S19	12273	0.004	0.2413	No
171	TICAM1	TICAM1 Entrez, Source	toll-like receptor adaptor molecule 1	12381	0.003	0.2363	No
172	PSMD14	PSMD14 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	12438	0.003	0.2337	No
173	CYLD	CYLD Entrez, Source	cylindromatosis (turban tumor syndrome)	12442	0.003	0.2337	No
174	DAB2IP	DAB2IP Entrez, Source	DAB2 interacting protein	12478	0.003	0.2321	No
175	PSMC2	PSMC2 Entrez, Source	proteasome (prosome, macropain) 26S subunit, ATPase, 2	12496	0.003	0.2314	No
176	MAVS			12529	0.002	0.2300	No
177	FBXW11	FBXW11 Entrez, Source	F-box and WD-40 domain protein 11	12575	0.002	0.2279	No
178	TBK1	TBK1 Entrez, Source	TANK-binding kinase 1	12578	0.002	0.2278	No
179	CREBBP	CREBBP Entrez, Source	CREB binding protein (Rubinstein-Taybi syndrome)	12588	0.002	0.2275	No
180	TANK	TANK Entrez, Source	TRAF family member-associated NFKB activator	12591	0.002	0.2275	No
181	PSMD10	PSMD10 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	12635	0.001	0.2255	No
182	UBC	UBC Entrez, Source	ubiquitin C	12666	0.001	0.2241	No
183	STAT2	STAT2 Entrez, Source	signal transducer and activator of transcription 2, 113kDa	12694	0.001	0.2228	No
184	ADAR	ADAR Entrez, Source	adenosine deaminase, RNA-specific	12746	0.000	0.2204	No
185	PSME3	PSME3 Entrez, Source	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	12757	0.000	0.2199	No
186	TRAFD1	TRAFD1 Entrez, Source	TRAF-type zinc finger domain containing 1	12764	0.000	0.2196	No
187	PSMD6	PSMD6 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	12776	0.000	0.2191	No
188	STAT5B	STAT5B Entrez, Source	signal transducer and activator of transcription 5B	12809	-0.000	0.2176	No
189	PSMD12	PSMD12 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	12816	-0.000	0.2173	No
190	TRIM5	TRIM5 Entrez, Source	tripartite motif-containing 5	12876	-0.001	0.2145	No
191	IFIH1	IFIH1 Entrez, Source	interferon induced with helicase C domain 1	12971	-0.001	0.2100	No
192	PYCARD	PYCARD Entrez, Source	PYD and CARD domain containing	13204	-0.003	0.1990	No
193	PSMA6	PSMA6 Entrez, Source	proteasome (prosome, macropain) subunit, alpha type, 6	13219	-0.004	0.1985	No
194	MALT1	MALT1 Entrez, Source	mucosa associated lymphoid tissue lymphoma translocation gene 1	13263	-0.004	0.1966	No
195	PSMD2	PSMD2 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	13293	-0.004	0.1954	No
196	PARP9	PARP9 Entrez, Source	poly (ADP-ribose) polymerase family, member 9	13341	-0.005	0.1933	No
197	LSM14A	LSM14A Entrez, Source	LSM14 homolog A (SCD6, S. cerevisiae)	13375	-0.005	0.1919	No
198	TRAF6	TRAF6 Entrez, Source	TNF receptor-associated factor 6	13413	-0.005	0.1903	No
199	SEC14L1	SEC14L1 Entrez, Source	SEC14-like 1 (S. cerevisiae)	13480	-0.006	0.1874	No
200	C1QBP	C1QBP Entrez, Source	complement component 1, q subcomponent binding protein	13553	-0.006	0.1842	No
201	SERPING1	SERPING1 Entrez, Source	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)	13582	-0.007	0.1831	No
202	SERPINB9	SERPINB9 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 9	13618	-0.007	0.1817	No
203	CUL1	CUL1 Entrez, Source	cullin 1	13641	-0.007	0.1810	No
204	PUM1	PUM1 Entrez, Source	pumilio homolog 1 (Drosophila)	13688	-0.008	0.1791	No
205	CHUK	CHUK Entrez, Source	conserved helix-loop-helix ubiquitous kinase	13754	-0.008	0.1763	No
206	FLOT2	FLOT2 Entrez, Source	flotillin 2	13790	-0.009	0.1750	No
207	PSMD5	PSMD5 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	13805	-0.009	0.1746	No
208	TAP1	TAP1 Entrez, Source	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	13807	-0.009	0.1750	No
209	NFKBIA	NFKBIA Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	13819	-0.009	0.1748	No
210	PSMB3	PSMB3 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 3	13827	-0.009	0.1748	No
211	A2M	A2M Entrez, Source	alpha-2-macroglobulin	13849	-0.009	0.1742	No
212	PIK3C3	PIK3C3 Entrez, Source	phosphoinositide-3-kinase, class 3	13944	-0.010	0.1701	No
213	CADM1			14041	-0.011	0.1659	No
214	XIAP			14066	-0.011	0.1652	No
215	PSMC6	PSMC6 Entrez, Source	proteasome (prosome, macropain) 26S subunit, ATPase, 6	14293	-0.013	0.1548	No
216	CD36	CD36 Entrez, Source	CD36 molecule (thrombospondin receptor)	14295	-0.013	0.1553	No
217	RFTN1	RFTN1 Entrez, Source	raftlin, lipid raft linker 1	14305	-0.013	0.1554	No
218	HLA-B	HLA-B Entrez, Source	major histocompatibility complex, class I, B	14319	-0.013	0.1553	No
219	LGR4	LGR4 Entrez, Source	leucine-rich repeat-containing G protein-coupled receptor 4	14343	-0.013	0.1547	No
220	PSMD4	PSMD4 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	14364	-0.013	0.1543	No
221	ZC3HAV1	ZC3HAV1 Entrez, Source	zinc finger CCCH-type, antiviral 1	14396	-0.014	0.1534	No
222	UBE2D3	UBE2D3 Entrez, Source	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	14465	-0.014	0.1507	No
223	PRKCD	PRKCD Entrez, Source	protein kinase C, delta	14536	-0.015	0.1479	No
224	RNF135	RNF135 Entrez, Source	ring finger protein 135	14612	-0.015	0.1449	No
225	IFNGR2	IFNGR2 Entrez, Source	interferon gamma receptor 2 (interferon gamma transducer 1)	14634	-0.016	0.1446	No
226	UBE2D2	UBE2D2 Entrez, Source	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	14677	-0.016	0.1432	No
227	IRF3	IRF3 Entrez, Source	interferon regulatory factor 3	14709	-0.016	0.1423	No
228	PSMA5	PSMA5 Entrez, Source	proteasome (prosome, macropain) subunit, alpha type, 5	14758	-0.017	0.1407	No
229	NMI	NMI Entrez, Source	N-myc (and STAT) interactor	14783	-0.017	0.1402	No
230	IFNGR1	IFNGR1 Entrez, Source	interferon gamma receptor 1	14812	-0.017	0.1396	No
231	PUM2	PUM2 Entrez, Source	pumilio homolog 2 (Drosophila)	14880	-0.018	0.1371	No
232	SIN3A	SIN3A Entrez, Source	SIN3 homolog A, transcription regulator (yeast)	14919	-0.018	0.1360	No
233	PSME2	PSME2 Entrez, Source	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	14955	-0.018	0.1350	No
234	POLR3C	POLR3C Entrez, Source	polymerase (RNA) III (DNA directed) polypeptide C (62kD)	15009	-0.019	0.1333	No
235	UBA52	UBA52 Entrez, Source	ubiquitin A-52 residue ribosomal protein fusion product 1	15098	-0.020	0.1298	No
236	PSMD13	PSMD13 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	15101	-0.020	0.1305	No
237	DHX58			15184	-0.020	0.1274	No
238	SUMO1	SUMO1 Entrez, Source	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	15259	-0.021	0.1247	No
239	PSMB8	PSMB8 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	15266	-0.021	0.1252	No
240	RIPK1	RIPK1 Entrez, Source	receptor (TNFRSF)-interacting serine-threonine kinase 1	15282	-0.021	0.1254	No
241	TAB1			15285	-0.021	0.1261	No
242	IKBKB	IKBKB Entrez, Source	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	15314	-0.022	0.1257	No
243	PSMC4	PSMC4 Entrez, Source	proteasome (prosome, macropain) 26S subunit, ATPase, 4	15335	-0.022	0.1256	No
244	RAF1	RAF1 Entrez, Source	v-raf-1 murine leukemia viral oncogene homolog 1	15362	-0.022	0.1252	No
245	MAP3K7	MAP3K7 Entrez, Source	mitogen-activated protein kinase kinase kinase 7	15371	-0.022	0.1257	No
246	DNAJA3	DNAJA3 Entrez, Source	DnaJ (Hsp40) homolog, subfamily A, member 3	15385	-0.022	0.1260	No
247	PSMA4	PSMA4 Entrez, Source	proteasome (prosome, macropain) subunit, alpha type, 4	15481	-0.023	0.1223	No
248	PSMB4	PSMB4 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 4	15527	-0.023	0.1211	No
249	PRKACA	PRKACA Entrez, Source	protein kinase, cAMP-dependent, catalytic, alpha	15636	-0.024	0.1169	No
250	FLOT1	FLOT1 Entrez, Source	flotillin 1	15663	-0.025	0.1166	No
251	PSMC3	PSMC3 Entrez, Source	proteasome (prosome, macropain) 26S subunit, ATPase, 3	15766	-0.025	0.1128	No
252	TAB3			15818	-0.026	0.1114	No
253	IRF7	IRF7 Entrez, Source	interferon regulatory factor 7	15840	-0.026	0.1114	No
254	PSMD3	PSMD3 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	15893	-0.027	0.1100	No
255	UBB	UBB Entrez, Source	ubiquitin B	15940	-0.027	0.1089	No
256	PSMA3	PSMA3 Entrez, Source	proteasome (prosome, macropain) subunit, alpha type, 3	15947	-0.027	0.1097	No
257	DDX60			16042	-0.028	0.1063	No
258	PSMB1	PSMB1 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 1	16242	-0.030	0.0979	No
259	UBE2N	UBE2N Entrez, Source	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	16312	-0.031	0.0959	No
260	HLA-A	HLA-A Entrez, Source	major histocompatibility complex, class I, A	16326	-0.031	0.0965	No
261	TMEM173	TMEM173 Entrez, Source	transmembrane protein 173	16386	-0.031	0.0949	No
262	PSMD8	PSMD8 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	16395	-0.032	0.0958	No
263	PSMF1	PSMF1 Entrez, Source	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	16453	-0.032	0.0944	No
264	PSMA7	PSMA7 Entrez, Source	proteasome (prosome, macropain) subunit, alpha type, 7	16484	-0.032	0.0942	No
265	PSMB6	PSMB6 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 6	16495	-0.032	0.0950	No
266	RPS27A	RPS27A Entrez, Source	ribosomal protein S27a	16508	-0.032	0.0958	No
267	RELA	RELA Entrez, Source	v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)	16661	-0.034	0.0898	No
268	BTRC	BTRC Entrez, Source	beta-transducin repeat containing	16693	-0.034	0.0897	No
269	POLR3G	POLR3G Entrez, Source	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	16794	-0.036	0.0864	No
270	MUL1			16967	-0.037	0.0796	No
271	HMGB1	HMGB1 Entrez, Source	high-mobility group box 1	17008	-0.038	0.0792	No
272	DDX58	DDX58 Entrez, Source	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	17183	-0.040	0.0724	No
273	NCR3	NCR3 Entrez, Source	natural cytotoxicity triggering receptor 3	17362	-0.042	0.0656	No
274	MAPKAPK3	MAPKAPK3 Entrez, Source	mitogen-activated protein kinase-activated protein kinase 3	17392	-0.042	0.0659	No
275	SKP1			17457	-0.043	0.0645	No
276	PSME1	PSME1 Entrez, Source	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	17553	-0.045	0.0618	No
277	IRAK4	IRAK4 Entrez, Source	interleukin-1 receptor-associated kinase 4	17589	-0.045	0.0619	No
278	CDC37	CDC37 Entrez, Source	CDC37 cell division cycle 37 homolog (S. cerevisiae)	17706	-0.047	0.0582	No
279	NR1H3	NR1H3 Entrez, Source	nuclear receptor subfamily 1, group H, member 3	17773	-0.048	0.0570	No
280	PDPK1	PDPK1 Entrez, Source	3-phosphoinositide dependent protein kinase-1	17787	-0.048	0.0583	No
281	NR1H2	NR1H2 Entrez, Source	nuclear receptor subfamily 1, group H, member 2	17853	-0.049	0.0571	No
282	RPS6KA5	RPS6KA5 Entrez, Source	ribosomal protein S6 kinase, 90kDa, polypeptide 5	17876	-0.049	0.0580	No
283	TSPAN6	TSPAN6 Entrez, Source	tetraspanin 6	17884	-0.049	0.0596	No
284	PSMC5	PSMC5 Entrez, Source	proteasome (prosome, macropain) 26S subunit, ATPase, 5	17886	-0.049	0.0616	No
285	PTPN1	PTPN1 Entrez, Source	protein tyrosine phosphatase, non-receptor type 1	18038	-0.052	0.0564	No
286	PPARG	PPARG Entrez, Source	peroxisome proliferative activated receptor, gamma	18288	-0.056	0.0467	No
287	FFAR2	FFAR2 Entrez, Source	free fatty acid receptor 2	18328	-0.056	0.0471	No
288	LTF	LTF Entrez, Source	lactotransferrin	18416	-0.058	0.0452	No
289	POLR3F	POLR3F Entrez, Source	polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa	18467	-0.059	0.0452	No
290	HLA-E	HLA-E Entrez, Source	major histocompatibility complex, class I, E	18485	-0.059	0.0468	No
291	HMGB2	HMGB2 Entrez, Source	high-mobility group box 2	18526	-0.060	0.0473	No
292	PGLYRP2	PGLYRP2 Entrez, Source	peptidoglycan recognition protein 2	18583	-0.061	0.0470	No
293	TNIP2	TNIP2 Entrez, Source	TNFAIP3 interacting protein 2	18649	-0.063	0.0464	No
294	IGF2	IGF2 Entrez, Source	insulin-like growth factor 2 (somatomedin A)	18794	-0.066	0.0422	No
295	HRAS	HRAS Entrez, Source	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	18923	-0.069	0.0388	No
296	PLSCR1	PLSCR1 Entrez, Source	phospholipid scramblase 1	18940	-0.069	0.0408	No
297	ICAM2	ICAM2 Entrez, Source	intercellular adhesion molecule 2	19340	-0.081	0.0249	No
298	PSMA1	PSMA1 Entrez, Source	proteasome (prosome, macropain) subunit, alpha type, 1	19344	-0.081	0.0280	No
299	PSMB9	PSMB9 Entrez, Source	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	19621	-0.091	0.0184	No
300	PSMD9	PSMD9 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	19651	-0.092	0.0207	No
301	NFKBIL1	NFKBIL1 Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1	19740	-0.095	0.0203	No
302	MAP2K6	MAP2K6 Entrez, Source	mitogen-activated protein kinase kinase 6	20166	-0.116	0.0046	No
303	IKBKG	IKBKG Entrez, Source	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	20251	-0.120	0.0054	No
304	MICA	MICA Entrez, Source	MHC class I polypeptide-related sequence A	20300	-0.123	0.0080	No
305	IRAK3	IRAK3 Entrez, Source	interleukin-1 receptor-associated kinase 3	20304	-0.124	0.0129	No
306	BCL10	BCL10 Entrez, Source	B-cell CLL/lymphoma 10	20313	-0.124	0.0175	No
307	TRIM6	TRIM6 Entrez, Source	tripartite motif-containing 6	20525	-0.142	0.0130	No
308	FADD	FADD Entrez, Source	Fas (TNFRSF6)-associated via death domain	20913	-0.199	0.0025	No
309	NR1D1	NR1D1 Entrez, Source	nuclear receptor subfamily 1, group D, member 1	20959	-0.213	0.0089	No