Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 1 |
| GeneSet | GO_RUFFLE_ORGANIZATION |
| Enrichment Score (ES) | 0.7064243 |
| Normalized Enrichment Score (NES) | 2.2903438 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.42031643 |
| FWER p-Value | 0.079 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PLEK | PLEK Entrez, Source | pleckstrin | 105 | 0.363 | 0.2229 | Yes |
| 2 | CCR7 | CCR7 Entrez, Source | chemokine (C-C motif) receptor 7 | 230 | 0.321 | 0.4179 | Yes |
| 3 | CSF1R | CSF1R Entrez, Source | colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog | 697 | 0.252 | 0.5537 | Yes |
| 4 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 752 | 0.248 | 0.7064 | Yes |
| 5 | PLEKHA1 | PLEKHA1 Entrez, Source | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 8398 | 0.046 | 0.3733 | No |
| 6 | PIP5K1A | PIP5K1A Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 9372 | 0.033 | 0.3479 | No |
| 7 | CYFIP1 | CYFIP1 Entrez, Source | cytoplasmic FMR1 interacting protein 1 | 10629 | 0.020 | 0.3008 | No |
| 8 | MTOR | 10857 | 0.018 | 0.3011 | No | ||
| 9 | CCL21 | CCL21 Entrez, Source | chemokine (C-C motif) ligand 21 | 11306 | 0.013 | 0.2883 | No |
| 10 | INPP5K | 11536 | 0.011 | 0.2845 | No | ||
| 11 | LIMA1 | LIMA1 Entrez, Source | LIM domain and actin binding 1 | 11591 | 0.011 | 0.2886 | No |
| 12 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 11818 | 0.009 | 0.2834 | No |
| 13 | INPPL1 | INPPL1 Entrez, Source | inositol polyphosphate phosphatase-like 1 | 11888 | 0.008 | 0.2850 | No |
| 14 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 13726 | -0.008 | 0.2031 | No |
| 15 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 13803 | -0.009 | 0.2050 | No |
| 16 | DBNL | DBNL Entrez, Source | drebrin-like | 14095 | -0.011 | 0.1982 | No |
| 17 | ARHGEF26 | 15741 | -0.025 | 0.1362 | No | ||
| 18 | ARFIP2 | ARFIP2 Entrez, Source | ADP-ribosylation factor interacting protein 2 (arfaptin 2) | 16155 | -0.029 | 0.1348 | No |
| 19 | CORO1B | CORO1B Entrez, Source | coronin, actin binding protein, 1B | 17728 | -0.047 | 0.0899 | No |
| 20 | BAG4 | BAG4 Entrez, Source | BCL2-associated athanogene 4 | 20143 | -0.114 | 0.0474 | No |
