DatasetNOV0093_collapsed_to_symbols.NOV0093.cls
#obese_versus_normal.NOV0093.cls
#obese_versus_normal_repos
PhenotypeNOV0093.cls#obese_versus_normal_repos
Upregulated in class1
GeneSetLINDSTEDT_DENDRITIC_CELL_MATURATION_D
Enrichment Score (ES)0.6288999
Normalized Enrichment Score (NES)2.137608
Nominal p-value0.0
FDR q-value0.23187488
FWER p-Value0.244
Table: GSEA Results Summary



Fig 1: Enrichment plot: LINDSTEDT_DENDRITIC_CELL_MATURATION_D   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ITGAMITGAM
Entrez,  Source
integrin, alpha M (complement component 3 receptor 3 subunit)130.4420.0661Yes
2CCR1CCR1
Entrez,  Source
chemokine (C-C motif) receptor 1220.4190.1291Yes
3FCER2FCER2
Entrez,  Source
Fc fragment of IgE, low affinity II, receptor for (CD23)590.3880.1860Yes
4P2RY6P2RY6
Entrez,  Source
pyrimidinergic receptor P2Y, G-protein coupled, 6970.3670.2397Yes
5CLEC10ACLEC10A
Entrez,  Source
C-type lectin domain family 10, member A1500.3440.2893Yes
6NCF2NCF2
Entrez,  Source
neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)2030.3270.3362Yes
7ITGAXITGAX
Entrez,  Source
integrin, alpha X (complement component 3 receptor 4 subunit)2230.3230.3841Yes
8CDH2CDH2
Entrez,  Source
cadherin 2, type 1, N-cadherin (neuronal)2270.3210.4325Yes
9ADCY7ADCY7
Entrez,  Source
adenylate cyclase 72990.3060.4754Yes
10F13A1F13A1
Entrez,  Source
coagulation factor XIII, A1 polypeptide3560.2950.5173Yes
11ITGB2ITGB2
Entrez,  Source
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)4330.2840.5567Yes
12LST1LST1
Entrez,  Source
leukocyte specific transcript 17350.2490.5800Yes
13IGSF6IGSF6
Entrez,  Source
immunoglobulin superfamily, member 69150.2340.6069Yes
14ACP5ACP5
Entrez,  Source
acid phosphatase 5, tartrate resistant11490.2190.6289Yes
15PTPREPTPRE
Entrez,  Source
protein tyrosine phosphatase, receptor type, E27070.1570.5788No
16EGR2EGR2
Entrez,  Source
early growth response 2 (Krox-20 homolog, Drosophila)28310.1540.5963No
17CCL22CCL22
Entrez,  Source
chemokine (C-C motif) ligand 2234570.1380.5874No
18DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)43450.1160.5629No
19MAN2B1MAN2B1
Entrez,  Source
mannosidase, alpha, class 2B, member 152810.0980.5333No
20MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)56700.0900.5286No
21RAB31RAB31
Entrez,  Source
RAB31, member RAS oncogene family62680.0800.5124No
22FGL2FGL2
Entrez,  Source
fibrinogen-like 263190.0790.5220No
23DNMT1DNMT1
Entrez,  Source
DNA (cytosine-5-)-methyltransferase 173830.0610.4809No
24ITGA5ITGA5
Entrez,  Source
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)77170.0560.4736No
25ATP6V1AATP6V1A
Entrez,  Source
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A78980.0530.4731No
26ITGAVITGAV
Entrez,  Source
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)79250.0530.4798No
27HLA-DMBHLA-DMB
Entrez,  Source
major histocompatibility complex, class II, DM beta79590.0520.4862No
28TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa80800.0510.4881No
29TPP1TPP1
Entrez,  Source
tripeptidyl peptidase I84210.0460.4789No
30RAP1GAPRAP1GAP
Entrez,  Source
RAP1 GTPase activating protein91100.0360.4517No
31ACTN1ACTN1
Entrez,  Source
actinin, alpha 191220.0360.4567No
32NAGANAGA
Entrez,  Source
N-acetylgalactosaminidase, alpha-95200.0310.4425No
33IFI16IFI16
Entrez,  Source
interferon, gamma-inducible protein 1697190.0290.4375No
34CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)97440.0290.4407No
35DNASE1L3DNASE1L3
Entrez,  Source
deoxyribonuclease I-like 397640.0290.4441No
36MTMR6MTMR6
Entrez,  Source
myotubularin related protein 698730.0270.4431No
37CIITACIITA
Entrez,  Source
class II, major histocompatibility complex, transactivator99560.0260.4432No
38ANXA1ANXA1
Entrez,  Source
annexin A1103590.0220.4275No
39NPR1NPR1
Entrez,  Source
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)104200.0220.4279No
40AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)112380.0140.3913No
41MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 1117050.0100.3707No
42TOP1TOP1
Entrez,  Source
topoisomerase (DNA) I122320.0050.3465No
43NCBP2NCBP2
Entrez,  Source
nuclear cap binding protein subunit 2, 20kDa123080.0040.3435No
44FCGRTFCGRT
Entrez,  Source
Fc fragment of IgG, receptor, transporter, alpha127780.0000.3213No
45DOCK1DOCK1
Entrez,  Source
dedicator of cytokinesis 113161-0.0030.3037No
46QSOX113190-0.0030.3028No
47DMPKDMPK
Entrez,  Source
dystrophia myotonica-protein kinase13703-0.0080.2797No
48TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)13726-0.0080.2799No
49NAAA14089-0.0110.2644No
50ARHGDIBARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta14101-0.0110.2656No
51RBMS2RBMS2
Entrez,  Source
RNA binding motif, single stranded interacting protein 214442-0.0140.2516No
52CTNND1CTNND1
Entrez,  Source
catenin (cadherin-associated protein), delta 114628-0.0160.2452No
53LAPTM4ALAPTM4A
Entrez,  Source
lysosomal-associated protein transmembrane 4 alpha14646-0.0160.2467No
54IFNGR1IFNGR1
Entrez,  Source
interferon gamma receptor 114812-0.0170.2415No
55SLC6A2SLC6A2
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 214947-0.0180.2379No
56CCNHCCNH
Entrez,  Source
cyclin H15640-0.0240.2088No
57PTGER3PTGER3
Entrez,  Source
prostaglandin E receptor 3 (subtype EP3)15693-0.0250.2101No
58HLA-DMAHLA-DMA
Entrez,  Source
major histocompatibility complex, class II, DM alpha16410-0.0320.1809No
59SLC1A5SLC1A5
Entrez,  Source
solute carrier family 1 (neutral amino acid transporter), member 516425-0.0320.1851No
60SYPL1SYPL1
Entrez,  Source
synaptophysin-like 117026-0.0380.1623No
61CLEC2BCLEC2B
Entrez,  Source
C-type lectin domain family 2, member B17580-0.0450.1429No
62RCBTB2RCBTB2
Entrez,  Source
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 218100-0.0530.1262No
63ALOX15ALOX15
Entrez,  Source
arachidonate 15-lipoxygenase20240-0.1200.0429No
Table: GSEA details [plain text format]



Fig 2: LINDSTEDT_DENDRITIC_CELL_MATURATION_D   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: LINDSTEDT_DENDRITIC_CELL_MATURATION_D: Random ES distribution   
Gene set null distribution of ES for LINDSTEDT_DENDRITIC_CELL_MATURATION_D