Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 0 |
| GeneSet | MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_5 |
| Enrichment Score (ES) | -0.50398415 |
| Normalized Enrichment Score (NES) | -1.7290927 |
| Nominal p-value | 0.018036073 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.991 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LAD1 | LAD1 Entrez, Source | ladinin 1 | 6421 | 0.077 | -0.2021 | No |
| 2 | DNAJA4 | DNAJA4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 4 | 10030 | 0.026 | -0.3392 | No |
| 3 | PSMB5 | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 10238 | 0.024 | -0.3180 | No |
| 4 | XPOT | XPOT Entrez, Source | exportin, tRNA (nuclear export receptor for tRNAs) | 12034 | 0.006 | -0.3945 | No |
| 5 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 13838 | -0.009 | -0.4679 | No |
| 6 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 14601 | -0.015 | -0.4839 | Yes |
| 7 | XBP1 | XBP1 Entrez, Source | X-box binding protein 1 | 14685 | -0.016 | -0.4667 | Yes |
| 8 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 14821 | -0.017 | -0.4505 | Yes |
| 9 | MLH1 | MLH1 Entrez, Source | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 14860 | -0.018 | -0.4291 | Yes |
| 10 | TARS | TARS Entrez, Source | threonyl-tRNA synthetase | 15107 | -0.020 | -0.4150 | Yes |
| 11 | MBTD1 | MBTD1 Entrez, Source | mbt domain containing 1 | 15374 | -0.022 | -0.3985 | Yes |
| 12 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 15648 | -0.024 | -0.3792 | Yes |
| 13 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 15736 | -0.025 | -0.3502 | Yes |
| 14 | BCL2L12 | BCL2L12 Entrez, Source | BCL2-like 12 (proline rich) | 15831 | -0.026 | -0.3202 | Yes |
| 15 | PCBP2 | PCBP2 Entrez, Source | poly(rC) binding protein 2 | 16444 | -0.032 | -0.3071 | Yes |
| 16 | SMPD1 | SMPD1 Entrez, Source | sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) | 16487 | -0.032 | -0.2666 | Yes |
| 17 | BTF3 | BTF3 Entrez, Source | basic transcription factor 3 | 17459 | -0.043 | -0.2557 | Yes |
| 18 | INPP5A | INPP5A Entrez, Source | inositol polyphosphate-5-phosphatase, 40kDa | 17814 | -0.048 | -0.2090 | Yes |
| 19 | CKS1B | CKS1B Entrez, Source | CDC28 protein kinase regulatory subunit 1B | 18541 | -0.060 | -0.1639 | Yes |
| 20 | ADK | ADK Entrez, Source | adenosine kinase | 19431 | -0.084 | -0.0958 | Yes |
| 21 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 20454 | -0.135 | 0.0327 | Yes |
