Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 0 |
| GeneSet | MORF_TERF2IP |
| Enrichment Score (ES) | -0.3663598 |
| Normalized Enrichment Score (NES) | -1.7754135 |
| Nominal p-value | 0.029288704 |
| FDR q-value | 0.8902517 |
| FWER p-Value | 0.972 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | H3F3A | H3F3A Entrez, Source | H3 histone, family 3A | 5365 | 0.096 | -0.2239 | No |
| 2 | TP53BP1 | TP53BP1 Entrez, Source | tumor protein p53 binding protein, 1 | 6764 | 0.071 | -0.2673 | No |
| 3 | KRAS | KRAS Entrez, Source | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 7196 | 0.064 | -0.2669 | No |
| 4 | BRD3 | BRD3 Entrez, Source | bromodomain containing 3 | 7399 | 0.061 | -0.2566 | No |
| 5 | TFAP4 | TFAP4 Entrez, Source | transcription factor AP-4 (activating enhancer binding protein 4) | 8172 | 0.049 | -0.2774 | No |
| 6 | STK38 | STK38 Entrez, Source | serine/threonine kinase 38 | 8516 | 0.044 | -0.2793 | No |
| 7 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 9119 | 0.036 | -0.2963 | No |
| 8 | CNOT1 | CNOT1 Entrez, Source | CCR4-NOT transcription complex, subunit 1 | 9362 | 0.033 | -0.2971 | No |
| 9 | DYRK2 | DYRK2 Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 9365 | 0.033 | -0.2865 | No |
| 10 | CHD8 | CHD8 Entrez, Source | chromodomain helicase DNA binding protein 8 | 9644 | 0.030 | -0.2900 | No |
| 11 | PLIN3 | 9784 | 0.028 | -0.2875 | No | ||
| 12 | XPO6 | XPO6 Entrez, Source | exportin 6 | 10595 | 0.020 | -0.3195 | No |
| 13 | TPR | TPR Entrez, Source | translocated promoter region (to activated MET oncogene) | 10611 | 0.020 | -0.3138 | No |
| 14 | SMARCC2 | SMARCC2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 10623 | 0.020 | -0.3079 | No |
| 15 | NFATC2IP | NFATC2IP Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein | 10653 | 0.019 | -0.3030 | No |
| 16 | CLSTN1 | CLSTN1 Entrez, Source | calsyntenin 1 | 10682 | 0.019 | -0.2981 | No |
| 17 | POLR2A | POLR2A Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 10684 | 0.019 | -0.2919 | No |
| 18 | ZC3H15 | 10801 | 0.018 | -0.2916 | No | ||
| 19 | BECN1 | BECN1 Entrez, Source | beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) | 10915 | 0.017 | -0.2914 | No |
| 20 | KBTBD2 | KBTBD2 Entrez, Source | kelch repeat and BTB (POZ) domain containing 2 | 10931 | 0.017 | -0.2866 | No |
| 21 | MARCH7 | MARCH7 Entrez, Source | membrane-associated ring finger (C3HC4) 7 | 11046 | 0.016 | -0.2869 | No |
| 22 | ALDH4A1 | ALDH4A1 Entrez, Source | aldehyde dehydrogenase 4 family, member A1 | 11398 | 0.013 | -0.2995 | No |
| 23 | DDB1 | DDB1 Entrez, Source | damage-specific DNA binding protein 1, 127kDa | 11486 | 0.012 | -0.2999 | No |
| 24 | METAP1 | METAP1 Entrez, Source | methionyl aminopeptidase 1 | 11523 | 0.011 | -0.2979 | No |
| 25 | ROCK1 | ROCK1 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 1 | 11611 | 0.011 | -0.2986 | No |
| 26 | CANX | CANX Entrez, Source | calnexin | 11717 | 0.010 | -0.3005 | No |
| 27 | UBN1 | UBN1 Entrez, Source | ubinuclein 1 | 11783 | 0.009 | -0.3007 | No |
| 28 | DHX38 | DHX38 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 38 | 11925 | 0.007 | -0.3050 | No |
| 29 | RAB1A | RAB1A Entrez, Source | RAB1A, member RAS oncogene family | 12002 | 0.007 | -0.3064 | No |
| 30 | HTATSF1 | HTATSF1 Entrez, Source | HIV-1 Tat specific factor 1 | 12163 | 0.005 | -0.3123 | No |
| 31 | CNPPD1 | 12176 | 0.005 | -0.3111 | No | ||
| 32 | CNP | CNP Entrez, Source | 2',3'-cyclic nucleotide 3' phosphodiesterase | 12224 | 0.005 | -0.3118 | No |
| 33 | ATXN2L | ATXN2L Entrez, Source | ataxin 2-like | 12375 | 0.004 | -0.3178 | No |
| 34 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12408 | 0.003 | -0.3182 | No |
| 35 | TIAL1 | TIAL1 Entrez, Source | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 12484 | 0.003 | -0.3210 | No |
| 36 | PHB | PHB Entrez, Source | prohibitin | 12848 | -0.000 | -0.3381 | No |
| 37 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 12927 | -0.001 | -0.3415 | No |
| 38 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 12987 | -0.002 | -0.3438 | No |
| 39 | CUX1 | 13138 | -0.003 | -0.3500 | No | ||
| 40 | DEK | DEK Entrez, Source | DEK oncogene (DNA binding) | 13215 | -0.004 | -0.3525 | No |
| 41 | SEC61B | SEC61B Entrez, Source | Sec61 beta subunit | 13278 | -0.004 | -0.3541 | No |
| 42 | RAB11A | RAB11A Entrez, Source | RAB11A, member RAS oncogene family | 13334 | -0.004 | -0.3553 | No |
| 43 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 13371 | -0.005 | -0.3554 | No |
| 44 | SNRNP200 | 13417 | -0.005 | -0.3559 | No | ||
| 45 | HNRNPK | 13513 | -0.006 | -0.3584 | No | ||
| 46 | PARN | PARN Entrez, Source | poly(A)-specific ribonuclease (deadenylation nuclease) | 13576 | -0.007 | -0.3592 | No |
| 47 | PWP1 | PWP1 Entrez, Source | PWP1 homolog (S. cerevisiae) | 13588 | -0.007 | -0.3576 | No |
| 48 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 13598 | -0.007 | -0.3558 | No |
| 49 | DNPEP | DNPEP Entrez, Source | aspartyl aminopeptidase | 13628 | -0.007 | -0.3548 | No |
| 50 | SRRT | 13674 | -0.008 | -0.3545 | No | ||
| 51 | FOXJ3 | FOXJ3 Entrez, Source | forkhead box J3 | 13843 | -0.009 | -0.3596 | No |
| 52 | RPRD2 | 13987 | -0.010 | -0.3630 | Yes | ||
| 53 | SMC5 | SMC5 Entrez, Source | structural maintenance of chromosomes 5 | 13997 | -0.010 | -0.3600 | Yes |
| 54 | SH2B1 | SH2B1 Entrez, Source | SH2B adaptor protein 1 | 14094 | -0.011 | -0.3610 | Yes |
| 55 | MORC3 | MORC3 Entrez, Source | MORC family CW-type zinc finger 3 | 14140 | -0.012 | -0.3593 | Yes |
| 56 | MFN2 | MFN2 Entrez, Source | mitofusin 2 | 14160 | -0.012 | -0.3564 | Yes |
| 57 | SEPT7 | SEPT7 Entrez, Source | septin 7 | 14185 | -0.012 | -0.3537 | Yes |
| 58 | DENND4A | DENND4A Entrez, Source | DENN/MADD domain containing 4A | 14202 | -0.012 | -0.3505 | Yes |
| 59 | ILF2 | ILF2 Entrez, Source | interleukin enhancer binding factor 2, 45kDa | 14237 | -0.012 | -0.3480 | Yes |
| 60 | KDM3B | 14284 | -0.013 | -0.3461 | Yes | ||
| 61 | BRD8 | BRD8 Entrez, Source | bromodomain containing 8 | 14324 | -0.013 | -0.3437 | Yes |
| 62 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 14465 | -0.014 | -0.3457 | Yes |
| 63 | EIF4H | 14494 | -0.014 | -0.3423 | Yes | ||
| 64 | CSNK1D | CSNK1D Entrez, Source | casein kinase 1, delta | 14525 | -0.015 | -0.3390 | Yes |
| 65 | PRKCSH | PRKCSH Entrez, Source | protein kinase C substrate 80K-H | 14526 | -0.015 | -0.3342 | Yes |
| 66 | NAP1L4 | NAP1L4 Entrez, Source | nucleosome assembly protein 1-like 4 | 14716 | -0.016 | -0.3379 | Yes |
| 67 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 14837 | -0.017 | -0.3380 | Yes |
| 68 | GPAA1 | GPAA1 Entrez, Source | glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) | 14868 | -0.018 | -0.3337 | Yes |
| 69 | SFSWAP | 14963 | -0.018 | -0.3321 | Yes | ||
| 70 | WWOX | WWOX Entrez, Source | WW domain containing oxidoreductase | 15199 | -0.020 | -0.3367 | Yes |
| 71 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 15362 | -0.022 | -0.3373 | Yes |
| 72 | IK | IK Entrez, Source | IK cytokine, down-regulator of HLA II | 15434 | -0.022 | -0.3333 | Yes |
| 73 | CNOT2 | CNOT2 Entrez, Source | CCR4-NOT transcription complex, subunit 2 | 15592 | -0.024 | -0.3330 | Yes |
| 74 | HNRNPH2 | 15660 | -0.025 | -0.3282 | Yes | ||
| 75 | COPS6 | COPS6 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 15733 | -0.025 | -0.3235 | Yes |
| 76 | CPSF4 | CPSF4 Entrez, Source | cleavage and polyadenylation specific factor 4, 30kDa | 15843 | -0.026 | -0.3202 | Yes |
| 77 | NUDT3 | NUDT3 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 15880 | -0.027 | -0.3133 | Yes |
| 78 | CNOT4 | CNOT4 Entrez, Source | CCR4-NOT transcription complex, subunit 4 | 15909 | -0.027 | -0.3059 | Yes |
| 79 | FBXO7 | FBXO7 Entrez, Source | F-box protein 7 | 16004 | -0.028 | -0.3014 | Yes |
| 80 | HNRNPH3 | 16142 | -0.029 | -0.2985 | Yes | ||
| 81 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 16147 | -0.029 | -0.2893 | Yes |
| 82 | B4GALT3 | B4GALT3 Entrez, Source | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 | 16149 | -0.029 | -0.2800 | Yes |
| 83 | IST1 | 16223 | -0.030 | -0.2738 | Yes | ||
| 84 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 16347 | -0.031 | -0.2696 | Yes |
| 85 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 16508 | -0.032 | -0.2666 | Yes |
| 86 | TERF2IP | TERF2IP Entrez, Source | telomeric repeat binding factor 2, interacting protein | 16623 | -0.034 | -0.2611 | Yes |
| 87 | NACA | NACA Entrez, Source | nascent-polypeptide-associated complex alpha polypeptide | 16761 | -0.035 | -0.2563 | Yes |
| 88 | CYHR1 | CYHR1 Entrez, Source | cysteine/histidine-rich 1 | 16772 | -0.035 | -0.2453 | Yes |
| 89 | PRKAG1 | PRKAG1 Entrez, Source | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 16813 | -0.036 | -0.2356 | Yes |
| 90 | SLC25A36 | SLC25A36 Entrez, Source | solute carrier family 25, member 36 | 16831 | -0.036 | -0.2248 | Yes |
| 91 | ARFGAP2 | 16955 | -0.037 | -0.2186 | Yes | ||
| 92 | RABAC1 | RABAC1 Entrez, Source | Rab acceptor 1 (prenylated) | 17211 | -0.040 | -0.2177 | Yes |
| 93 | TOR1AIP1 | TOR1AIP1 Entrez, Source | torsin A interacting protein 1 | 17251 | -0.041 | -0.2064 | Yes |
| 94 | NFYB | NFYB Entrez, Source | nuclear transcription factor Y, beta | 17258 | -0.041 | -0.1934 | Yes |
| 95 | DNAJC8 | DNAJC8 Entrez, Source | DnaJ (Hsp40) homolog, subfamily C, member 8 | 17303 | -0.041 | -0.1822 | Yes |
| 96 | OTUB1 | OTUB1 Entrez, Source | OTU domain, ubiquitin aldehyde binding 1 | 17321 | -0.041 | -0.1695 | Yes |
| 97 | COX7A2L | COX7A2L Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 like | 17551 | -0.044 | -0.1660 | Yes |
| 98 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 17637 | -0.046 | -0.1552 | Yes |
| 99 | MKRN1 | MKRN1 Entrez, Source | makorin, ring finger protein, 1 | 17655 | -0.046 | -0.1411 | Yes |
| 100 | GNB5 | GNB5 Entrez, Source | guanine nucleotide binding protein (G protein), beta 5 | 17912 | -0.050 | -0.1372 | Yes |
| 101 | TAF9 | TAF9 Entrez, Source | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 17940 | -0.050 | -0.1223 | Yes |
| 102 | SUMO2 | SUMO2 Entrez, Source | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 17967 | -0.050 | -0.1071 | Yes |
| 103 | STK19 | STK19 Entrez, Source | serine/threonine kinase 19 | 17994 | -0.051 | -0.0919 | Yes |
| 104 | CNBP | CNBP Entrez, Source | CCHC-type zinc finger, nucleic acid binding protein | 18090 | -0.052 | -0.0794 | Yes |
| 105 | DRG2 | DRG2 Entrez, Source | developmentally regulated GTP binding protein 2 | 18092 | -0.052 | -0.0624 | Yes |
| 106 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 18208 | -0.054 | -0.0503 | Yes |
| 107 | PRKRA | PRKRA Entrez, Source | protein kinase, interferon-inducible double stranded RNA dependent activator | 18514 | -0.060 | -0.0453 | Yes |
| 108 | DRG1 | DRG1 Entrez, Source | developmentally regulated GTP binding protein 1 | 19132 | -0.075 | -0.0505 | Yes |
| 109 | TBCC | TBCC Entrez, Source | tubulin-specific chaperone c | 20514 | -0.141 | -0.0704 | Yes |
| 110 | ZNHIT3 | ZNHIT3 Entrez, Source | zinc finger, HIT type 3 | 20639 | -0.155 | -0.0262 | Yes |
| 111 | NUBP1 | NUBP1 Entrez, Source | nucleotide binding protein 1 (MinD homolog, E. coli) | 20642 | -0.155 | 0.0239 | Yes |
