Details for gene set REACTOME_INNATE_IMMUNE_SYSTEM[GSEA]

Table: GSEA Results Summary

Dataset	NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos
Phenotype	NOV0093.cls#obese_versus_normal_repos
Upregulated in class	1
GeneSet	REACTOME_INNATE_IMMUNE_SYSTEM
Enrichment Score (ES)	0.48059565
Normalized Enrichment Score (NES)	2.1976297
Nominal p-value	0.0
FDR q-value	0.22596528
FWER p-Value	0.149

Fig 1: Enrichment plot: REACTOME_INNATE_IMMUNE_SYSTEM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CR1	CR1 Entrez,  Source	complement component (3b/4b) receptor 1 (Knops blood group)	20	0.420	0.0251	Yes
2	C4BPB	C4BPB Entrez,  Source	complement component 4 binding protein, beta	23	0.417	0.0508	Yes
3	BTK	BTK Entrez,  Source	Bruton agammaglobulinemia tyrosine kinase	28	0.412	0.0761	Yes
4	NLRC4			78	0.376	0.0971	Yes
5	TLR6	TLR6 Entrez,  Source	toll-like receptor 6	104	0.365	0.1185	Yes
6	TLR8	TLR8 Entrez,  Source	toll-like receptor 8	144	0.346	0.1380	Yes
7	PSTPIP1	PSTPIP1 Entrez,  Source	proline-serine-threonine phosphatase interacting protein 1	154	0.344	0.1589	Yes
8	NLRP3			174	0.335	0.1787	Yes
9	C1QC	C1QC Entrez,  Source	complement component 1, q subcomponent, C chain	207	0.326	0.1974	Yes
10	C1QB	C1QB Entrez,  Source	complement component 1, q subcomponent, B chain	244	0.317	0.2153	Yes
11	C1QA	C1QA Entrez,  Source	complement component 1, q subcomponent, A chain	263	0.313	0.2338	Yes
12	TLR7	TLR7 Entrez,  Source	toll-like receptor 7	292	0.306	0.2514	Yes
13	C2	C2 Entrez,  Source	complement component 2	375	0.292	0.2656	Yes
14	LBP	LBP Entrez,  Source	lipopolysaccharide binding protein	391	0.290	0.2829	Yes
15	MASP1	MASP1 Entrez,  Source	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	562	0.267	0.2913	Yes
16	LY86	LY86 Entrez,  Source	lymphocyte antigen 86	609	0.261	0.3052	Yes
17	NOD2			948	0.232	0.3035	Yes
18	CCR2	CCR2 Entrez,  Source	chemokine (C-C motif) receptor 2	959	0.231	0.3173	Yes
19	CD180	CD180 Entrez,  Source	CD180 molecule	1012	0.228	0.3289	Yes
20	IKBKE	IKBKE Entrez,  Source	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	1083	0.223	0.3393	Yes
21	TLR10	TLR10 Entrez,  Source	toll-like receptor 10	1131	0.220	0.3507	Yes
22	LGMN	LGMN Entrez,  Source	legumain	1335	0.209	0.3539	Yes
23	DNM1	DNM1 Entrez,  Source	dynamin 1	1443	0.202	0.3614	Yes
24	DEFB124	DEFB124 Entrez,  Source	defensin, beta 124	1461	0.201	0.3730	Yes
25	CARD9	CARD9 Entrez,  Source	caspase recruitment domain family, member 9	1535	0.199	0.3818	Yes
26	P2RX7	P2RX7 Entrez,  Source	purinergic receptor P2X, ligand-gated ion channel, 7	1711	0.191	0.3853	Yes
27	CD4	CD4 Entrez,  Source	CD4 molecule	1736	0.190	0.3959	Yes
28	TLR2	TLR2 Entrez,  Source	toll-like receptor 2	1778	0.188	0.4056	Yes
29	BIRC3	BIRC3 Entrez,  Source	baculoviral IAP repeat-containing 3	1781	0.188	0.4172	Yes
30	C7	C7 Entrez,  Source	complement component 7	1814	0.187	0.4272	Yes
31	ZBP1	ZBP1 Entrez,  Source	Z-DNA binding protein 1	1934	0.182	0.4328	Yes
32	TLR1	TLR1 Entrez,  Source	toll-like receptor 1	1968	0.181	0.4425	Yes
33	RIPK2	RIPK2 Entrez,  Source	receptor-interacting serine-threonine kinase 2	2184	0.173	0.4429	Yes
34	TNFAIP3	TNFAIP3 Entrez,  Source	tumor necrosis factor, alpha-induced protein 3	2212	0.172	0.4522	Yes
35	CD14	CD14 Entrez,  Source	CD14 molecule	2213	0.172	0.4629	Yes
36	TIRAP	TIRAP Entrez,  Source	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	2521	0.163	0.4583	Yes
37	CFB	CFB Entrez,  Source	complement factor B	2554	0.162	0.4668	Yes
38	TLR5	TLR5 Entrez,  Source	toll-like receptor 5	2606	0.160	0.4743	Yes
39	LY96	LY96 Entrez,  Source	lymphocyte antigen 96	2680	0.158	0.4806	Yes
40	CTSS	CTSS Entrez,  Source	cathepsin S	3174	0.145	0.4660	No
41	C4BPA	C4BPA Entrez,  Source	complement component 4 binding protein, alpha	3548	0.136	0.4566	No
42	PANX1	PANX1 Entrez,  Source	pannexin 1	3751	0.131	0.4551	No
43	TRAF3	TRAF3 Entrez,  Source	TNF receptor-associated factor 3	4211	0.120	0.4406	No
44	CD55	CD55 Entrez,  Source	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	4214	0.119	0.4479	No
45	CFD	CFD Entrez,  Source	complement factor D (adipsin)	4697	0.109	0.4316	No
46	CDK1			4779	0.107	0.4344	No
47	MASP2	MASP2 Entrez,  Source	mannan-binding lectin serine peptidase 2	4829	0.107	0.4387	No
48	RPS6KA1	RPS6KA1 Entrez,  Source	ribosomal protein S6 kinase, 90kDa, polypeptide 1	5175	0.100	0.4284	No
49	CFH	CFH Entrez,  Source	complement factor H	5454	0.094	0.4209	No
50	C1S	C1S Entrez,  Source	complement component 1, s subcomponent	5557	0.092	0.4218	No
51	C3	C3 Entrez,  Source	complement component 3	5562	0.092	0.4273	No
52	C5	C5 Entrez,  Source	complement component 5	6059	0.083	0.4088	No
53	PELI1	PELI1 Entrez,  Source	pellino homolog 1 (Drosophila)	6181	0.081	0.4080	No
54	MEFV	MEFV Entrez,  Source	Mediterranean fever	6338	0.079	0.4055	No
55	TLR3	TLR3 Entrez,  Source	toll-like receptor 3	6628	0.074	0.3962	No
56	MAP2K1	MAP2K1 Entrez,  Source	mitogen-activated protein kinase kinase 1	6827	0.070	0.3911	No
57	AIM2	AIM2 Entrez,  Source	absent in melanoma 2	6999	0.068	0.3872	No
58	PPP2R1B	PPP2R1B Entrez,  Source	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform	7097	0.066	0.3866	No
59	IRAK2	IRAK2 Entrez,  Source	interleukin-1 receptor-associated kinase 2	7265	0.063	0.3826	No
60	C4A	C4A Entrez,  Source	complement component 4A (Rodgers blood group)	7862	0.054	0.3574	No
61	UBE2D1	UBE2D1 Entrez,  Source	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	7960	0.052	0.3561	No
62	CTSB	CTSB Entrez,  Source	cathepsin B	8199	0.049	0.3477	No
63	NOD1			8480	0.045	0.3371	No
64	AGER	AGER Entrez,  Source	advanced glycosylation end product-specific receptor	8536	0.044	0.3372	No
65	MYD88	MYD88 Entrez,  Source	myeloid differentiation primary response gene (88)	8547	0.044	0.3394	No
66	DEFB1	DEFB1 Entrez,  Source	defensin, beta 1	8881	0.039	0.3260	No
67	C6	C6 Entrez,  Source	complement component 6	9053	0.037	0.3201	No
68	NLRX1			9128	0.036	0.3188	No
69	CTSK	CTSK Entrez,  Source	cathepsin K (pycnodysostosis)	9272	0.034	0.3140	No
70	IRAK1	IRAK1 Entrez,  Source	interleukin-1 receptor-associated kinase 1	9314	0.034	0.3142	No
71	HSP90B1	HSP90B1 Entrez,  Source	heat shock protein 90kDa beta (Grp94), member 1	9474	0.032	0.3085	No
72	DUSP3	DUSP3 Entrez,  Source	dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)	9492	0.031	0.3097	No
73	CNPY3			9531	0.031	0.3098	No
74	TXN	TXN Entrez,  Source	thioredoxin	9604	0.030	0.3082	No
75	MAP2K3	MAP2K3 Entrez,  Source	mitogen-activated protein kinase kinase 3	9671	0.029	0.3069	No
76	SAA1	SAA1 Entrez,  Source	serum amyloid A1	9707	0.029	0.3070	No
77	BCL2L1	BCL2L1 Entrez,  Source	BCL2-like 1	10130	0.025	0.2884	No
78	ISG15	ISG15 Entrez,  Source	ISG15 ubiquitin-like modifier	10219	0.024	0.2857	No
79	PIK3R4	PIK3R4 Entrez,  Source	phosphoinositide-3-kinase, regulatory subunit 4, p150	10298	0.023	0.2834	No
80	PROS1	PROS1 Entrez,  Source	protein S (alpha)	10362	0.022	0.2817	No
81	MEF2A	MEF2A Entrez,  Source	MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)	10381	0.022	0.2822	No
82	NLRC5			10403	0.022	0.2826	No
83	TLR4	TLR4 Entrez,  Source	toll-like receptor 4	10488	0.021	0.2799	No
84	BIRC2	BIRC2 Entrez,  Source	baculoviral IAP repeat-containing 2	10505	0.021	0.2804	No
85	NFKB2	NFKB2 Entrez,  Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	10587	0.020	0.2778	No
86	RPS6KA3	RPS6KA3 Entrez,  Source	ribosomal protein S6 kinase, 90kDa, polypeptide 3	10604	0.020	0.2782	No
87	MAP3K1	MAP3K1 Entrez,  Source	mitogen-activated protein kinase kinase kinase 1	10662	0.019	0.2767	No
88	TAB2			10793	0.018	0.2716	No
89	MAPK1	MAPK1 Entrez,  Source	mitogen-activated protein kinase 1	10802	0.018	0.2724	No
90	UNC93B1	UNC93B1 Entrez,  Source	unc-93 homolog B1 (C. elegans)	10829	0.018	0.2722	No
91	CASP8	CASP8 Entrez,  Source	caspase 8, apoptosis-related cysteine peptidase	10927	0.017	0.2687	No
92	TAX1BP1	TAX1BP1 Entrez,  Source	Tax1 (human T-cell leukemia virus type I) binding protein 1	11114	0.015	0.2607	No
93	DDOST	DDOST Entrez,  Source	dolichyl-diphosphooligosaccharide-protein glycosyltransferase	11133	0.015	0.2608	No
94	MAPK12	MAPK12 Entrez,  Source	mitogen-activated protein kinase 12	11158	0.015	0.2606	No
95	PLCG2	PLCG2 Entrez,  Source	phospholipase C, gamma 2 (phosphatidylinositol-specific)	11182	0.015	0.2604	No
96	IRF1	IRF1 Entrez,  Source	interferon regulatory factor 1	11218	0.014	0.2596	No
97	APP	APP Entrez,  Source	amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)	11277	0.014	0.2577	No
98	PPP2R5D	PPP2R5D Entrez,  Source	protein phosphatase 2, regulatory subunit B (B56), delta isoform	11287	0.014	0.2581	No
99	MAPKAPK2	MAPKAPK2 Entrez,  Source	mitogen-activated protein kinase-activated protein kinase 2	11342	0.013	0.2563	No
100	SIKE1			11404	0.013	0.2542	No
101	EP300	EP300 Entrez,  Source	E1A binding protein p300	11472	0.012	0.2517	No
102	CAPZA1	CAPZA1 Entrez,  Source	capping protein (actin filament) muscle Z-line, alpha 1	11584	0.011	0.2471	No
103	UBE2K			11589	0.011	0.2476	No
104	DEFB132			11903	0.008	0.2331	No
105	CASP10	CASP10 Entrez,  Source	caspase 10, apoptosis-related cysteine peptidase	11941	0.007	0.2318	No
106	HSP90AB1	HSP90AB1 Entrez,  Source	heat shock protein 90kDa alpha (cytosolic), class B member 1	12158	0.005	0.2218	No
107	RNF125	RNF125 Entrez,  Source	ring finger protein 125	12347	0.004	0.2131	No
108	TICAM1	TICAM1 Entrez,  Source	toll-like receptor adaptor molecule 1	12381	0.003	0.2117	No
109	EEA1	EEA1 Entrez,  Source	early endosome antigen 1, 162kD	12389	0.003	0.2116	No
110	PELI3	PELI3 Entrez,  Source	pellino homolog 3 (Drosophila)	12421	0.003	0.2103	No
111	CYLD	CYLD Entrez,  Source	cylindromatosis (turban tumor syndrome)	12442	0.003	0.2095	No
112	MAVS			12529	0.002	0.2056	No
113	TBK1	TBK1 Entrez,  Source	TANK-binding kinase 1	12578	0.002	0.2034	No
114	CREBBP	CREBBP Entrez,  Source	CREB binding protein (Rubinstein-Taybi syndrome)	12588	0.002	0.2031	No
115	TANK	TANK Entrez,  Source	TRAF family member-associated NFKB activator	12591	0.002	0.2031	No
116	CASP1	CASP1 Entrez,  Source	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	12705	0.001	0.1977	No
117	PPP2CA	PPP2CA Entrez,  Source	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	12927	-0.001	0.1872	No
118	IFIH1	IFIH1 Entrez,  Source	interferon induced with helicase C domain 1	12971	-0.001	0.1853	No
119	DNM2	DNM2 Entrez,  Source	dynamin 2	13109	-0.003	0.1789	No
120	PYCARD	PYCARD Entrez,  Source	PYD and CARD domain containing	13204	-0.003	0.1746	No
121	PELI2	PELI2 Entrez,  Source	pellino homolog 2 (Drosophila)	13249	-0.004	0.1728	No
122	MAPK13	MAPK13 Entrez,  Source	mitogen-activated protein kinase 13	13340	-0.005	0.1687	No
123	TRAF6	TRAF6 Entrez,  Source	TNF receptor-associated factor 6	13413	-0.005	0.1656	No
124	MAP2K2	MAP2K2 Entrez,  Source	mitogen-activated protein kinase kinase 2	13418	-0.005	0.1658	No
125	CASP2	CASP2 Entrez,  Source	caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)	13482	-0.006	0.1631	No
126	CD46	CD46 Entrez,  Source	CD46 molecule, complement regulatory protein	13595	-0.007	0.1582	No
127	CHUK	CHUK Entrez,  Source	conserved helix-loop-helix ubiquitous kinase	13754	-0.008	0.1512	No
128	NFKBIA	NFKBIA Entrez,  Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	13819	-0.009	0.1487	No
129	PIK3C3	PIK3C3 Entrez,  Source	phosphoinositide-3-kinase, class 3	13944	-0.010	0.1434	No
130	MAPK9	MAPK9 Entrez,  Source	mitogen-activated protein kinase 9	14359	-0.013	0.1244	No
131	UBE2D3	UBE2D3 Entrez,  Source	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	14465	-0.014	0.1203	No
132	PRKCSH	PRKCSH Entrez,  Source	protein kinase C substrate 80K-H	14526	-0.015	0.1183	No
133	RNF135	RNF135 Entrez,  Source	ring finger protein 135	14612	-0.015	0.1152	No
134	UBA7			14637	-0.016	0.1151	No
135	UBE2D2	UBE2D2 Entrez,  Source	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	14677	-0.016	0.1142	No
136	IRF3	IRF3 Entrez,  Source	interferon regulatory factor 3	14709	-0.016	0.1137	No
137	CREB1	CREB1 Entrez,  Source	cAMP responsive element binding protein 1	14742	-0.017	0.1132	No
138	TRIM25	TRIM25 Entrez,  Source	tripartite motif-containing 25	14862	-0.018	0.1086	No
139	BCL2	BCL2 Entrez,  Source	B-cell CLL/lymphoma 2	14895	-0.018	0.1082	No
140	MAPK14	MAPK14 Entrez,  Source	mitogen-activated protein kinase 14	15039	-0.019	0.1026	No
141	UBA52	UBA52 Entrez,  Source	ubiquitin A-52 residue ribosomal protein fusion product 1	15098	-0.020	0.1010	No
142	DHX58			15184	-0.020	0.0982	No
143	RIPK1	RIPK1 Entrez,  Source	receptor (TNFRSF)-interacting serine-threonine kinase 1	15282	-0.021	0.0949	No
144	TAB1			15285	-0.021	0.0961	No
145	ATG5	ATG5 Entrez,  Source	ATG5 autophagy related 5 homolog (S. cerevisiae)	15288	-0.021	0.0973	No
146	IKBKB	IKBKB Entrez,  Source	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	15314	-0.022	0.0975	No
147	MAP3K7	MAP3K7 Entrez,  Source	mitogen-activated protein kinase kinase kinase 7	15371	-0.022	0.0962	No
148	IRF2	IRF2 Entrez,  Source	interferon regulatory factor 2	15518	-0.023	0.0906	No
149	OTUD5	OTUD5 Entrez,  Source	OTU domain containing 5	15529	-0.023	0.0916	No
150	ATF2	ATF2 Entrez,  Source	activating transcription factor 2	15645	-0.024	0.0876	No
151	TAB3			15818	-0.026	0.0810	No
152	DUSP6	DUSP6 Entrez,  Source	dual specificity phosphatase 6	15822	-0.026	0.0825	No
153	IRF7	IRF7 Entrez,  Source	interferon regulatory factor 7	15840	-0.026	0.0833	No
154	MAPK8	MAPK8 Entrez,  Source	mitogen-activated protein kinase 8	15844	-0.026	0.0848	No
155	MAP2K7	MAP2K7 Entrez,  Source	mitogen-activated protein kinase kinase 7	15866	-0.026	0.0854	No
156	PPP2R1A	PPP2R1A Entrez,  Source	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	15949	-0.027	0.0832	No
157	RPS6KA2	RPS6KA2 Entrez,  Source	ribosomal protein S6 kinase, 90kDa, polypeptide 2	16028	-0.028	0.0812	No
158	S100B	S100B Entrez,  Source	S100 calcium binding protein B	16029	-0.028	0.0829	No
159	CAPZA2	CAPZA2 Entrez,  Source	capping protein (actin filament) muscle Z-line, alpha 2	16112	-0.029	0.0808	No
160	UBE2N	UBE2N Entrez,  Source	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	16312	-0.031	0.0732	No
161	PCBP2	PCBP2 Entrez,  Source	poly(rC) binding protein 2	16444	-0.032	0.0689	No
162	CASP4	CASP4 Entrez,  Source	caspase 4, apoptosis-related cysteine peptidase	16448	-0.032	0.0708	No
163	TRAF2	TRAF2 Entrez,  Source	TNF receptor-associated factor 2	16465	-0.032	0.0720	No
164	RPS27A	RPS27A Entrez,  Source	ribosomal protein S27a	16508	-0.032	0.0720	No
165	JUN	JUN Entrez,  Source	jun oncogene	16551	-0.033	0.0720	No
166	PPP2CB	PPP2CB Entrez,  Source	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	16622	-0.034	0.0708	No
167	MAPK7	MAPK7 Entrez,  Source	mitogen-activated protein kinase 7	16652	-0.034	0.0715	No
168	RELA	RELA Entrez,  Source	v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)	16661	-0.034	0.0732	No
169	MEF2C	MEF2C Entrez,  Source	MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)	16718	-0.035	0.0727	No
170	UBE2L6	UBE2L6 Entrez,  Source	ubiquitin-conjugating enzyme E2L 6	16857	-0.036	0.0683	No
171	HMGB1	HMGB1 Entrez,  Source	high-mobility group box 1	17008	-0.038	0.0635	No
172	ATG12	ATG12 Entrez,  Source	ATG12 autophagy related 12 homolog (S. cerevisiae)	17057	-0.038	0.0636	No
173	DDX58	DDX58 Entrez,  Source	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	17183	-0.040	0.0601	No
174	FOS	FOS Entrez,  Source	v-fos FBJ murine osteosarcoma viral oncogene homolog	17345	-0.042	0.0550	No
175	NFKBIB	NFKBIB Entrez,  Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	17373	-0.042	0.0563	No
176	MAPKAPK3	MAPKAPK3 Entrez,  Source	mitogen-activated protein kinase-activated protein kinase 3	17392	-0.042	0.0581	No
177	NLRP1			17480	-0.044	0.0566	No
178	IRAK4	IRAK4 Entrez,  Source	interleukin-1 receptor-associated kinase 4	17589	-0.045	0.0542	No
179	ELK1	ELK1 Entrez,  Source	ELK1, member of ETS oncogene family	17714	-0.047	0.0512	No
180	ATF1	ATF1 Entrez,  Source	activating transcription factor 1	17871	-0.049	0.0468	No
181	RPS6KA5	RPS6KA5 Entrez,  Source	ribosomal protein S6 kinase, 90kDa, polypeptide 5	17876	-0.049	0.0497	No
182	MAP2K4	MAP2K4 Entrez,  Source	mitogen-activated protein kinase kinase 4	18117	-0.053	0.0415	No
183	MAPK3	MAPK3 Entrez,  Source	mitogen-activated protein kinase 3	18147	-0.053	0.0434	No
184	MAPK10	MAPK10 Entrez,  Source	mitogen-activated protein kinase 10	18210	-0.054	0.0438	No
185	ECSIT	ECSIT Entrez,  Source	ECSIT homolog (Drosophila)	18346	-0.057	0.0408	No
186	CASP9	CASP9 Entrez,  Source	caspase 9, apoptosis-related cysteine peptidase	18355	-0.057	0.0440	No
187	LGALS3	LGALS3 Entrez,  Source	lectin, galactoside-binding, soluble, 3 (galectin 3)	18384	-0.057	0.0462	No
188	MAPK11	MAPK11 Entrez,  Source	mitogen-activated protein kinase 11	18392	-0.058	0.0494	No
189	PIN1	PIN1 Entrez,  Source	protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1	18542	-0.060	0.0461	No
190	DUSP7	DUSP7 Entrez,  Source	dual specificity phosphatase 7	18973	-0.070	0.0299	No
191	CFI	CFI Entrez,  Source	complement factor I	19102	-0.074	0.0283	No
192	C8G	C8G Entrez,  Source	complement component 8, gamma polypeptide	19112	-0.074	0.0325	No
193	SIGIRR	SIGIRR Entrez,  Source	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	19248	-0.078	0.0309	No
194	HERC5	HERC5 Entrez,  Source	hect domain and RLD 5	19337	-0.081	0.0317	No
195	TXNIP	TXNIP Entrez,  Source	thioredoxin interacting protein	19385	-0.083	0.0346	No
196	DUSP4	DUSP4 Entrez,  Source	dual specificity phosphatase 4	19784	-0.097	0.0216	No
197	MAP2K6	MAP2K6 Entrez,  Source	mitogen-activated protein kinase kinase 6	20166	-0.116	0.0105	No
198	IKBKG	IKBKG Entrez,  Source	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	20251	-0.120	0.0140	No
199	IRAK3	IRAK3 Entrez,  Source	interleukin-1 receptor-associated kinase 3	20304	-0.124	0.0192	No
200	RIPK3	RIPK3 Entrez,  Source	receptor-interacting serine-threonine kinase 3	20489	-0.137	0.0189	No
201	FADD	FADD Entrez,  Source	Fas (TNFRSF6)-associated via death domain	20913	-0.199	0.0110	No

Fig 2: REACTOME_INNATE_IMMUNE_SYSTEM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_INNATE_IMMUNE_SYSTEM: Random ES distribution   
Gene set null distribution of ES for REACTOME_INNATE_IMMUNE_SYSTEM