Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 0 |
| GeneSet | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A5 |
| Enrichment Score (ES) | -0.43587616 |
| Normalized Enrichment Score (NES) | -1.9672991 |
| Nominal p-value | 0.003976143 |
| FDR q-value | 0.2551075 |
| FWER p-Value | 0.601 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DLX4 | DLX4 Entrez, Source | distal-less homeobox 4 | 926 | 0.233 | 0.0277 | No |
| 2 | ARHGEF18 | ARHGEF18 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 18 | 2218 | 0.172 | 0.0191 | No |
| 3 | ZNF443 | ZNF443 Entrez, Source | zinc finger protein 443 | 4419 | 0.115 | -0.0500 | No |
| 4 | AP1M2 | AP1M2 Entrez, Source | adaptor-related protein complex 1, mu 2 subunit | 6509 | 0.076 | -0.1259 | No |
| 5 | SEZ6L2 | SEZ6L2 Entrez, Source | seizure related 6 homolog (mouse)-like 2 | 8089 | 0.051 | -0.1852 | No |
| 6 | SMARCA4 | SMARCA4 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 8315 | 0.047 | -0.1815 | No |
| 7 | RUFY3 | RUFY3 Entrez, Source | RUN and FYVE domain containing 3 | 9457 | 0.032 | -0.2258 | No |
| 8 | DNAJB1 | DNAJB1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 1 | 9866 | 0.027 | -0.2368 | No |
| 9 | ZNF562 | ZNF562 Entrez, Source | zinc finger protein 562 | 10043 | 0.025 | -0.2373 | No |
| 10 | CHERP | CHERP Entrez, Source | calcium homeostasis endoplasmic reticulum protein | 10140 | 0.025 | -0.2343 | No |
| 11 | NR2F6 | NR2F6 Entrez, Source | nuclear receptor subfamily 2, group F, member 6 | 10208 | 0.024 | -0.2302 | No |
| 12 | OTUD3 | OTUD3 Entrez, Source | OTU domain containing 3 | 10642 | 0.020 | -0.2447 | No |
| 13 | RIPK4 | RIPK4 Entrez, Source | receptor-interacting serine-threonine kinase 4 | 10871 | 0.018 | -0.2501 | No |
| 14 | YIPF2 | YIPF2 Entrez, Source | Yip1 domain family, member 2 | 10960 | 0.017 | -0.2492 | No |
| 15 | ZNF518A | 12058 | 0.006 | -0.2993 | No | ||
| 16 | GGA2 | GGA2 Entrez, Source | golgi associated, gamma adaptin ear containing, ARF binding protein 2 | 12147 | 0.005 | -0.3018 | No |
| 17 | L3MBTL1 | 12553 | 0.002 | -0.3204 | No | ||
| 18 | TSN | TSN Entrez, Source | translin | 13186 | -0.003 | -0.3494 | No |
| 19 | TLE2 | TLE2 Entrez, Source | transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) | 13538 | -0.006 | -0.3641 | No |
| 20 | CDK16 | 13762 | -0.008 | -0.3721 | No | ||
| 21 | ARID4A | ARID4A Entrez, Source | AT rich interactive domain 4A (RBP1-like) | 14186 | -0.012 | -0.3885 | No |
| 22 | LCMT1 | LCMT1 Entrez, Source | leucine carboxyl methyltransferase 1 | 14200 | -0.012 | -0.3853 | No |
| 23 | FBRS | 14631 | -0.016 | -0.4010 | No | ||
| 24 | RANBP3 | RANBP3 Entrez, Source | RAN binding protein 3 | 14696 | -0.016 | -0.3991 | No |
| 25 | ZNF358 | ZNF358 Entrez, Source | zinc finger protein 358 | 14887 | -0.018 | -0.4026 | No |
| 26 | HAUS5 | 14899 | -0.018 | -0.3976 | No | ||
| 27 | CD2BP2 | CD2BP2 Entrez, Source | CD2 (cytoplasmic tail) binding protein 2 | 14987 | -0.019 | -0.3960 | No |
| 28 | SIN3B | SIN3B Entrez, Source | SIN3 homolog B, transcription regulator (yeast) | 15052 | -0.019 | -0.3932 | No |
| 29 | ARID3A | ARID3A Entrez, Source | AT rich interactive domain 3A (BRIGHT- like) | 15240 | -0.021 | -0.3956 | No |
| 30 | FZR1 | FZR1 Entrez, Source | fizzy/cell division cycle 20 related 1 (Drosophila) | 15296 | -0.021 | -0.3917 | No |
| 31 | WDR33 | WDR33 Entrez, Source | WD repeat domain 33 | 15345 | -0.022 | -0.3873 | No |
| 32 | VSIG10 | 15574 | -0.024 | -0.3908 | No | ||
| 33 | KDM4B | 16526 | -0.033 | -0.4259 | Yes | ||
| 34 | F11R | F11R Entrez, Source | F11 receptor | 16615 | -0.034 | -0.4198 | Yes |
| 35 | ZNF444 | ZNF444 Entrez, Source | zinc finger protein 444 | 16691 | -0.034 | -0.4128 | Yes |
| 36 | RALGAPA1 | 16802 | -0.036 | -0.4071 | Yes | ||
| 37 | EFS | EFS Entrez, Source | embryonal Fyn-associated substrate | 16810 | -0.036 | -0.3965 | Yes |
| 38 | SHC2 | SHC2 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 2 | 17013 | -0.038 | -0.3945 | Yes |
| 39 | XAB2 | XAB2 Entrez, Source | XPA binding protein 2 | 17169 | -0.040 | -0.3897 | Yes |
| 40 | ANKS1A | ANKS1A Entrez, Source | ankyrin repeat and sterile alpha motif domain containing 1A | 17341 | -0.042 | -0.3850 | Yes |
| 41 | ZSCAN18 | 17452 | -0.043 | -0.3770 | Yes | ||
| 42 | PKP4 | PKP4 Entrez, Source | plakophilin 4 | 17490 | -0.044 | -0.3654 | Yes |
| 43 | GNA11 | GNA11 Entrez, Source | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 17746 | -0.047 | -0.3630 | Yes |
| 44 | MKNK2 | MKNK2 Entrez, Source | MAP kinase interacting serine/threonine kinase 2 | 17948 | -0.050 | -0.3571 | Yes |
| 45 | CERS4 | 18030 | -0.051 | -0.3452 | Yes | ||
| 46 | HOOK2 | HOOK2 Entrez, Source | hook homolog 2 (Drosophila) | 18109 | -0.053 | -0.3328 | Yes |
| 47 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 18364 | -0.057 | -0.3273 | Yes |
| 48 | DNAJB2 | DNAJB2 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 2 | 18598 | -0.062 | -0.3195 | Yes |
| 49 | DCAF15 | 18820 | -0.067 | -0.3095 | Yes | ||
| 50 | SLC25A23 | SLC25A23 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 | 18826 | -0.067 | -0.2893 | Yes |
| 51 | ARMCX5 | ARMCX5 Entrez, Source | armadillo repeat containing, X-linked 5 | 18889 | -0.068 | -0.2714 | Yes |
| 52 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 18955 | -0.070 | -0.2531 | Yes |
| 53 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 18977 | -0.070 | -0.2326 | Yes |
| 54 | RTN2 | RTN2 Entrez, Source | reticulon 2 | 19341 | -0.081 | -0.2249 | Yes |
| 55 | EPOR | EPOR Entrez, Source | erythropoietin receptor | 19497 | -0.086 | -0.2058 | Yes |
| 56 | KLHL26 | KLHL26 Entrez, Source | kelch-like 26 (Drosophila) | 19546 | -0.088 | -0.1811 | Yes |
| 57 | ZNF34 | ZNF34 Entrez, Source | zinc finger protein 34 | 20382 | -0.129 | -0.1812 | Yes |
| 58 | PGAP1 | PGAP1 Entrez, Source | - | 20439 | -0.133 | -0.1431 | Yes |
| 59 | DHRS2 | DHRS2 Entrez, Source | dehydrogenase/reductase (SDR family) member 2 | 20742 | -0.170 | -0.1054 | Yes |
| 60 | ZFP37 | ZFP37 Entrez, Source | zinc finger protein 37 homolog (mouse) | 20796 | -0.179 | -0.0532 | Yes |
| 61 | SYT17 | SYT17 Entrez, Source | synaptotagmin XVII | 21000 | -0.227 | 0.0068 | Yes |
