Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_D0_fat_corrected_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 0 |
| GeneSet | CRGAARNNNNCGA_UNKNOWN |
| Enrichment Score (ES) | -0.5050756 |
| Normalized Enrichment Score (NES) | -1.6824206 |
| Nominal p-value | 0.0019762847 |
| FDR q-value | 0.4220658 |
| FWER p-Value | 0.81 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SPTAN1 | SPTAN1 Entrez, Source | spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) | 8118 | 0.039 | -0.0972 | No |
| 2 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 8617 | 0.037 | -0.0638 | No |
| 3 | TLN1 | TLN1 Entrez, Source | talin 1 | 8842 | 0.036 | -0.0267 | No |
| 4 | ZBTB33 | ZBTB33 Entrez, Source | zinc finger and BTB domain containing 33 | 12380 | 0.025 | -0.0602 | No |
| 5 | SPATS2 | SPATS2 Entrez, Source | spermatogenesis associated, serine-rich 2 | 13654 | 0.021 | -0.0578 | No |
| 6 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 17374 | 0.014 | -0.1071 | No |
| 7 | SLC30A7 | SLC30A7 Entrez, Source | solute carrier family 30 (zinc transporter), member 7 | 18848 | 0.011 | -0.1198 | No |
| 8 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 19959 | 0.010 | -0.1282 | No |
| 9 | BZW1 | BZW1 Entrez, Source | basic leucine zipper and W2 domains 1 | 22164 | 0.007 | -0.1591 | No |
| 10 | ACIN1 | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 22390 | 0.006 | -0.1557 | No |
| 11 | MED12 | MED12 Entrez, Source | mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae) | 22443 | 0.006 | -0.1493 | No |
| 12 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 22509 | 0.006 | -0.1433 | No |
| 13 | EXTL2 | EXTL2 Entrez, Source | exostoses (multiple)-like 2 | 24190 | 0.004 | -0.1675 | No |
| 14 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 26572 | 0.002 | -0.2070 | No |
| 15 | WAC | WAC Entrez, Source | WW domain containing adaptor with coiled-coil | 40034 | -0.002 | -0.4399 | No |
| 16 | MPP5 | MPP5 Entrez, Source | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | 40617 | -0.003 | -0.4471 | No |
| 17 | TMUB1 | TMUB1 Entrez, Source | transmembrane and ubiquitin-like domain containing 1 | 41496 | -0.004 | -0.4581 | No |
| 18 | MTA2 | MTA2 Entrez, Source | metastasis associated 1 family, member 2 | 42486 | -0.005 | -0.4698 | No |
| 19 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 42947 | -0.005 | -0.4719 | No |
| 20 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 43134 | -0.005 | -0.4689 | No |
| 21 | AIP | AIP Entrez, Source | aryl hydrocarbon receptor interacting protein | 43251 | -0.006 | -0.4645 | No |
| 22 | BCL11B | BCL11B Entrez, Source | B-cell CLL/lymphoma 11B (zinc finger protein) | 44680 | -0.008 | -0.4807 | No |
| 23 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 44795 | -0.008 | -0.4739 | No |
| 24 | RNF115 | 44949 | -0.008 | -0.4674 | No | ||
| 25 | FOXO4 | 45325 | -0.009 | -0.4642 | No | ||
| 26 | CREB3 | CREB3 Entrez, Source | cAMP responsive element binding protein 3 | 46098 | -0.010 | -0.4664 | No |
| 27 | UBE2M | UBE2M Entrez, Source | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 48315 | -0.014 | -0.4891 | Yes |
| 28 | PRPF19 | PRPF19 Entrez, Source | PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) | 48926 | -0.015 | -0.4823 | Yes |
| 29 | ARGLU1 | 49138 | -0.016 | -0.4680 | Yes | ||
| 30 | SERINC2 | SERINC2 Entrez, Source | serine incorporator 2 | 49337 | -0.016 | -0.4530 | Yes |
| 31 | DARS | DARS Entrez, Source | aspartyl-tRNA synthetase | 49361 | -0.016 | -0.4347 | Yes |
| 32 | TPT1 | TPT1 Entrez, Source | tumor protein, translationally-controlled 1 | 49589 | -0.017 | -0.4195 | Yes |
| 33 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 50360 | -0.019 | -0.4114 | Yes |
| 34 | EEF1B2 | EEF1B2 Entrez, Source | eukaryotic translation elongation factor 1 beta 2 | 50444 | -0.019 | -0.3910 | Yes |
| 35 | RABEP2 | RABEP2 Entrez, Source | rabaptin, RAB GTPase binding effector protein 2 | 51339 | -0.022 | -0.3815 | Yes |
| 36 | EIF1B | EIF1B Entrez, Source | eukaryotic translation initiation factor 1B | 52209 | -0.025 | -0.3681 | Yes |
| 37 | KIRREL2 | KIRREL2 Entrez, Source | kin of IRRE like 2 (Drosophila) | 52684 | -0.027 | -0.3455 | Yes |
| 38 | PTBP2 | PTBP2 Entrez, Source | polypyrimidine tract binding protein 2 | 53352 | -0.030 | -0.3227 | Yes |
| 39 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 53386 | -0.030 | -0.2886 | Yes |
| 40 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 55167 | -0.043 | -0.2700 | Yes |
| 41 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 55881 | -0.053 | -0.2218 | Yes |
| 42 | RBM24 | RBM24 Entrez, Source | RNA binding motif protein 24 | 56245 | -0.059 | -0.1600 | Yes |
| 43 | LEF1 | LEF1 Entrez, Source | lymphoid enhancer-binding factor 1 | 56477 | -0.065 | -0.0896 | Yes |
| 44 | PIK3R2 | PIK3R2 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta) | 57043 | -0.091 | 0.0054 | Yes |
