Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_D0_fat_corrected_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 1 |
| GeneSet | GO_AMINOPEPTIDASE_ACTIVITY |
| Enrichment Score (ES) | 0.66947883 |
| Normalized Enrichment Score (NES) | 1.7652608 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.46 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DPP6 | DPP6 Entrez, Source | dipeptidyl-peptidase 6 | 37 | 0.254 | 0.1676 | Yes |
| 2 | XPNPEP2 | XPNPEP2 Entrez, Source | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | 72 | 0.215 | 0.3096 | Yes |
| 3 | TRHDE | TRHDE Entrez, Source | thyrotropin-releasing hormone degrading enzyme | 1283 | 0.098 | 0.3533 | Yes |
| 4 | DPP3 | DPP3 Entrez, Source | dipeptidyl-peptidase 3 | 1518 | 0.093 | 0.4109 | Yes |
| 5 | DPEP2 | DPEP2 Entrez, Source | dipeptidase 2 | 1533 | 0.093 | 0.4721 | Yes |
| 6 | ERAP2 | 2687 | 0.075 | 0.5014 | Yes | ||
| 7 | PEPD | PEPD Entrez, Source | peptidase D | 2796 | 0.073 | 0.5480 | Yes |
| 8 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 2996 | 0.071 | 0.5914 | Yes |
| 9 | LNPEP | LNPEP Entrez, Source | leucyl/cystinyl aminopeptidase | 3523 | 0.066 | 0.6257 | Yes |
| 10 | ERAP1 | 3803 | 0.063 | 0.6626 | Yes | ||
| 11 | PHEX | PHEX Entrez, Source | phosphate regulating endopeptidase homolog, X-linked (hypophosphatemia, vitamin D resistant rickets) | 6158 | 0.048 | 0.6531 | Yes |
| 12 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 6888 | 0.044 | 0.6695 | Yes |
| 13 | PRCP | PRCP Entrez, Source | prolylcarboxypeptidase (angiotensinase C) | 13167 | 0.023 | 0.5750 | No |
| 14 | PRSS16 | PRSS16 Entrez, Source | protease, serine, 16 (thymus) | 13488 | 0.022 | 0.5839 | No |
| 15 | XPNPEP1 | XPNPEP1 Entrez, Source | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 14490 | 0.020 | 0.5793 | No |
| 16 | BLMH | BLMH Entrez, Source | bleomycin hydrolase | 16583 | 0.015 | 0.5529 | No |
| 17 | DPEP1 | DPEP1 Entrez, Source | dipeptidase 1 (renal) | 17195 | 0.014 | 0.5515 | No |
| 18 | F11 | F11 Entrez, Source | coagulation factor XI (plasma thromboplastin antecedent) | 20137 | 0.009 | 0.5064 | No |
| 19 | XPNPEP3 | XPNPEP3 Entrez, Source | X-prolyl aminopeptidase (aminopeptidase P) 3, putative | 20642 | 0.009 | 0.5033 | No |
| 20 | RNPEP | RNPEP Entrez, Source | arginyl aminopeptidase (aminopeptidase B) | 22672 | 0.006 | 0.4719 | No |
| 21 | METAP1D | 27251 | 0.001 | 0.3926 | No | ||
| 22 | TPP2 | TPP2 Entrez, Source | tripeptidyl peptidase II | 27544 | 0.000 | 0.3877 | No |
| 23 | METAP2 | METAP2 Entrez, Source | methionyl aminopeptidase 2 | 39016 | -0.000 | 0.1878 | No |
| 24 | DNPEP | DNPEP Entrez, Source | aspartyl aminopeptidase | 39098 | -0.000 | 0.1866 | No |
| 25 | DPP9 | DPP9 Entrez, Source | dipeptidyl-peptidase 9 | 39707 | -0.001 | 0.1768 | No |
| 26 | RNPEPL1 | RNPEPL1 Entrez, Source | arginyl aminopeptidase (aminopeptidase B)-like 1 | 39961 | -0.002 | 0.1735 | No |
| 27 | METAP1 | METAP1 Entrez, Source | methionyl aminopeptidase 1 | 40095 | -0.002 | 0.1723 | No |
| 28 | DPP8 | DPP8 Entrez, Source | dipeptidyl-peptidase 8 | 40614 | -0.003 | 0.1650 | No |
| 29 | NPEPL1 | NPEPL1 Entrez, Source | aminopeptidase-like 1 | 42311 | -0.005 | 0.1385 | No |
| 30 | ENPEP | ENPEP Entrez, Source | glutamyl aminopeptidase (aminopeptidase A) | 43111 | -0.005 | 0.1281 | No |
| 31 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 43583 | -0.006 | 0.1239 | No |
| 32 | ANPEP | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 45889 | -0.009 | 0.0900 | No |
| 33 | DPP7 | DPP7 Entrez, Source | dipeptidyl-peptidase 7 | 46076 | -0.010 | 0.0932 | No |
| 34 | CTSH | CTSH Entrez, Source | cathepsin H | 46734 | -0.011 | 0.0889 | No |
| 35 | LTA4H | LTA4H Entrez, Source | leukotriene A4 hydrolase | 47261 | -0.012 | 0.0876 | No |
| 36 | NPEPPS | NPEPPS Entrez, Source | aminopeptidase puromycin sensitive | 48239 | -0.014 | 0.0797 | No |
| 37 | DPEP3 | DPEP3 Entrez, Source | dipeptidase 3 | 51945 | -0.024 | 0.0309 | No |
| 38 | DPP10 | DPP10 Entrez, Source | dipeptidyl-peptidase 10 | 53445 | -0.030 | 0.0249 | No |
| 39 | NAALAD2 | NAALAD2 Entrez, Source | N-acetylated alpha-linked acidic dipeptidase 2 | 56492 | -0.065 | 0.0150 | No |
