Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NOV0093_D0_fat_corrected_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos |
| Phenotype | NOV0093.cls#obese_versus_normal_repos |
| Upregulated in class | 0 |
| GeneSet | GO_ENDORIBONUCLEASE_COMPLEX |
| Enrichment Score (ES) | -0.6414218 |
| Normalized Enrichment Score (NES) | -1.5314901 |
| Nominal p-value | 0.03909465 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.998 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DROSHA | 15159 | 0.018 | -0.2083 | No | ||
| 2 | POP1 | POP1 Entrez, Source | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) | 16236 | 0.016 | -0.1779 | No |
| 3 | RPP38 | RPP38 Entrez, Source | ribonuclease P/MRP 38kDa subunit | 18711 | 0.011 | -0.1854 | No |
| 4 | ERN1 | ERN1 Entrez, Source | endoplasmic reticulum to nucleus signalling 1 | 19405 | 0.010 | -0.1653 | No |
| 5 | DGCR8 | DGCR8 Entrez, Source | DiGeorge syndrome critical region gene 8 | 26443 | 0.002 | -0.2818 | No |
| 6 | POP5 | POP5 Entrez, Source | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) | 27730 | 0.000 | -0.3037 | No |
| 7 | POP4 | POP4 Entrez, Source | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 40393 | -0.002 | -0.5177 | No |
| 8 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 44686 | -0.008 | -0.5691 | No |
| 9 | TARBP2 | TARBP2 Entrez, Source | Tar (HIV-1) RNA binding protein 2 | 46911 | -0.011 | -0.5732 | No |
| 10 | RPP30 | RPP30 Entrez, Source | ribonuclease P/MRP 30kDa subunit | 50823 | -0.020 | -0.5789 | Yes |
| 11 | TSEN54 | TSEN54 Entrez, Source | tRNA splicing endonuclease 54 homolog (S. cerevisiae) | 51276 | -0.022 | -0.5196 | Yes |
| 12 | TSEN2 | TSEN2 Entrez, Source | tRNA splicing endonuclease 2 homolog (S. cerevisiae) | 51398 | -0.022 | -0.4532 | Yes |
| 13 | TSEN34 | TSEN34 Entrez, Source | tRNA splicing endonuclease 34 homolog (S. cerevisiae) | 51851 | -0.024 | -0.3880 | Yes |
| 14 | CLP1 | 53477 | -0.031 | -0.3212 | Yes | ||
| 15 | POP7 | POP7 Entrez, Source | processing of precursor 7, ribonuclease P subunit (S. cerevisiae) | 53562 | -0.031 | -0.2262 | Yes |
| 16 | RPP40 | RPP40 Entrez, Source | ribonuclease P 40kDa subunit | 54144 | -0.035 | -0.1283 | Yes |
| 17 | RPP21 | RPP21 Entrez, Source | ribonuclease P 21kDa subunit | 56243 | -0.059 | 0.0193 | Yes |
