Details for gene set MORF_TERF2IP[GSEA]

Table: GSEA Results Summary

Dataset	NOV0093_D0_fat_corrected_collapsed_to_symbols.NOV0093.cls #obese_versus_normal.NOV0093.cls #obese_versus_normal_repos
Phenotype	NOV0093.cls#obese_versus_normal_repos
Upregulated in class	0
GeneSet	MORF_TERF2IP
Enrichment Score (ES)	-0.3687365
Normalized Enrichment Score (NES)	-1.4801
Nominal p-value	0.044401545
FDR q-value	1.0
FWER p-Value	1.0

Fig 1: Enrichment plot: MORF_TERF2IP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ALDH4A1	ALDH4A1 Entrez,  Source	aldehyde dehydrogenase 4 family, member A1	8148	0.039	-0.1156	No
2	H3F3A	H3F3A Entrez,  Source	H3 histone, family 3A	9447	0.034	-0.1150	No
3	KRAS	KRAS Entrez,  Source	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	9595	0.033	-0.0947	No
4	BRD3	BRD3 Entrez,  Source	bromodomain containing 3	10543	0.030	-0.0907	No
5	TP53BP1	TP53BP1 Entrez,  Source	tumor protein p53 binding protein, 1	10577	0.030	-0.0708	No
6	STK38	STK38 Entrez,  Source	serine/threonine kinase 38	10646	0.029	-0.0516	No
7	ROCK1	ROCK1 Entrez,  Source	Rho-associated, coiled-coil containing protein kinase 1	15574	0.017	-0.1258	No
8	CNOT1	CNOT1 Entrez,  Source	CCR4-NOT transcription complex, subunit 1	16423	0.016	-0.1299	No
9	KBTBD2	KBTBD2 Entrez,  Source	kelch repeat and BTB (POZ) domain containing 2	16679	0.015	-0.1240	No
10	SMARCC2	SMARCC2 Entrez,  Source	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	16887	0.015	-0.1175	No
11	CHD8	CHD8 Entrez,  Source	chromodomain helicase DNA binding protein 8	16995	0.014	-0.1094	No
12	POLR2A	POLR2A Entrez,  Source	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	17089	0.014	-0.1012	No
13	TPR	TPR Entrez,  Source	translocated promoter region (to activated MET oncogene)	17096	0.014	-0.0915	No
14	BECN1	BECN1 Entrez,  Source	beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)	17107	0.014	-0.0819	No
15	SLC9A1	SLC9A1 Entrez,  Source	solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive)	17128	0.014	-0.0725	No
16	DYRK2	DYRK2 Entrez,  Source	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	17197	0.014	-0.0640	No
17	ZC3H15			17277	0.014	-0.0558	No
18	CNPPD1			17933	0.013	-0.0584	No
19	RAB1A	RAB1A Entrez,  Source	RAB1A, member RAS oncogene family	18293	0.012	-0.0563	No
20	MARCH7	MARCH7 Entrez,  Source	membrane-associated ring finger (C3HC4) 7	18643	0.012	-0.0544	No
21	PLIN3			18727	0.011	-0.0479	No
22	DDB1	DDB1 Entrez,  Source	damage-specific DNA binding protein 1, 127kDa	18746	0.011	-0.0403	No
23	XPO6	XPO6 Entrez,  Source	exportin 6	18869	0.011	-0.0346	No
24	NFATC2IP	NFATC2IP Entrez,  Source	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein	18956	0.011	-0.0284	No
25	CUX1			19808	0.010	-0.0365	No
26	HTATSF1	HTATSF1 Entrez,  Source	HIV-1 Tat specific factor 1	19868	0.010	-0.0308	No
27	CANX	CANX Entrez,  Source	calnexin	20964	0.008	-0.0443	No
28	UBN1	UBN1 Entrez,  Source	ubinuclein 1	21051	0.008	-0.0402	No
29	DHX38	DHX38 Entrez,  Source	DEAH (Asp-Glu-Ala-His) box polypeptide 38	21651	0.007	-0.0456	No
30	CNP	CNP Entrez,  Source	2',3'-cyclic nucleotide 3' phosphodiesterase	22056	0.007	-0.0480	No
31	CAPZB	CAPZB Entrez,  Source	capping protein (actin filament) muscle Z-line, beta	23823	0.005	-0.0756	No
32	TFAP4	TFAP4 Entrez,  Source	transcription factor AP-4 (activating enhancer binding protein 4)	24220	0.004	-0.0794	No
33	CLSTN1	CLSTN1 Entrez,  Source	calsyntenin 1	25609	0.003	-0.1015	No
34	PHB	PHB Entrez,  Source	prohibitin	25803	0.003	-0.1029	No
35	PPP2CA	PPP2CA Entrez,  Source	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	26013	0.003	-0.1047	No
36	PWP1	PWP1 Entrez,  Source	PWP1 homolog (S. cerevisiae)	26064	0.003	-0.1038	No
37	SMAD2	SMAD2 Entrez,  Source	SMAD, mothers against DPP homolog 2 (Drosophila)	26153	0.002	-0.1036	No
38	YWHAQ	YWHAQ Entrez,  Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	26167	0.002	-0.1022	No
39	RAB11A	RAB11A Entrez,  Source	RAB11A, member RAS oncogene family	26300	0.002	-0.1029	No
40	MFN2	MFN2 Entrez,  Source	mitofusin 2	26314	0.002	-0.1016	No
41	TIAL1	TIAL1 Entrez,  Source	TIA1 cytotoxic granule-associated RNA binding protein-like 1	26320	0.002	-0.1002	No
42	SEC61B	SEC61B Entrez,  Source	Sec61 beta subunit	26503	0.002	-0.1020	No
43	SEPT7	SEPT7 Entrez,  Source	septin 7	26702	0.002	-0.1044	No
44	ATXN2L	ATXN2L Entrez,  Source	ataxin 2-like	27071	0.001	-0.1101	No
45	FOXJ3	FOXJ3 Entrez,  Source	forkhead box J3	27516	0.000	-0.1175	No
46	DNPEP	DNPEP Entrez,  Source	aspartyl aminopeptidase	39098	-0.000	-0.3196	No
47	PARN	PARN Entrez,  Source	poly(A)-specific ribonuclease (deadenylation nuclease)	39175	-0.001	-0.3206	No
48	DENND4A	DENND4A Entrez,  Source	DENN/MADD domain containing 4A	39283	-0.001	-0.3220	No
49	WWOX	WWOX Entrez,  Source	WW domain containing oxidoreductase	39838	-0.001	-0.3307	No
50	HNRNPK			39967	-0.002	-0.3318	No
51	METAP1	METAP1 Entrez,  Source	methionyl aminopeptidase 1	40095	-0.002	-0.3328	No
52	RPRD2			40258	-0.002	-0.3342	No
53	DEK	DEK Entrez,  Source	DEK oncogene (DNA binding)	40377	-0.002	-0.3348	No
54	MORC3	MORC3 Entrez,  Source	MORC family CW-type zinc finger 3	41059	-0.003	-0.3444	No
55	SNRNP200			41061	-0.003	-0.3422	No
56	KHDRBS1	KHDRBS1 Entrez,  Source	KH domain containing, RNA binding, signal transduction associated 1	41097	-0.003	-0.3405	No
57	NUDT3	NUDT3 Entrez,  Source	nudix (nucleoside diphosphate linked moiety X)-type motif 3	41426	-0.004	-0.3437	No
58	SH2B1	SH2B1 Entrez,  Source	SH2B adaptor protein 1	41546	-0.004	-0.3431	No
59	EIF4H			42193	-0.005	-0.3512	No
60	UBE2D3	UBE2D3 Entrez,  Source	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	42925	-0.005	-0.3604	No
61	KDM3B			43157	-0.005	-0.3606	No
62	SMC5	SMC5 Entrez,  Source	structural maintenance of chromosomes 5	43457	-0.006	-0.3618	No
63	SRRT			43774	-0.006	-0.3629	No
64	GPAA1	GPAA1 Entrez,  Source	glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)	43781	-0.006	-0.3586	No
65	COPS6	COPS6 Entrez,  Source	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	43998	-0.007	-0.3577	No
66	CALM2	CALM2 Entrez,  Source	calmodulin 2 (phosphorylase kinase, delta)	44133	-0.007	-0.3553	No
67	CSNK1D	CSNK1D Entrez,  Source	casein kinase 1, delta	44902	-0.008	-0.3633	Yes
68	SMNDC1	SMNDC1 Entrez,  Source	survival motor neuron domain containing 1	44982	-0.008	-0.3591	Yes
69	CNOT4	CNOT4 Entrez,  Source	CCR4-NOT transcription complex, subunit 4	44993	-0.008	-0.3538	Yes
70	SFSWAP			45018	-0.008	-0.3486	Yes
71	NAP1L4	NAP1L4 Entrez,  Source	nucleosome assembly protein 1-like 4	45041	-0.008	-0.3434	Yes
72	IK	IK Entrez,  Source	IK cytokine, down-regulator of HLA II	45201	-0.008	-0.3404	Yes
73	CPSF4	CPSF4 Entrez,  Source	cleavage and polyadenylation specific factor 4, 30kDa	45216	-0.008	-0.3348	Yes
74	BRD8	BRD8 Entrez,  Source	bromodomain containing 8	45641	-0.009	-0.3360	Yes
75	RAF1	RAF1 Entrez,  Source	v-raf-1 murine leukemia viral oncogene homolog 1	45899	-0.009	-0.3340	Yes
76	ILF2	ILF2 Entrez,  Source	interleukin enhancer binding factor 2, 45kDa	46099	-0.010	-0.3306	Yes
77	PRKCSH	PRKCSH Entrez,  Source	protein kinase C substrate 80K-H	46394	-0.010	-0.3286	Yes
78	CNOT2	CNOT2 Entrez,  Source	CCR4-NOT transcription complex, subunit 2	46479	-0.010	-0.3229	Yes
79	HNRNPH2			46599	-0.011	-0.3176	Yes
80	FBXO7	FBXO7 Entrez,  Source	F-box protein 7	46611	-0.011	-0.3104	Yes
81	PRKAG1	PRKAG1 Entrez,  Source	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	47204	-0.012	-0.3126	Yes
82	TERF2IP	TERF2IP Entrez,  Source	telomeric repeat binding factor 2, interacting protein	47260	-0.012	-0.3054	Yes
83	RABAC1	RABAC1 Entrez,  Source	Rab acceptor 1 (prenylated)	47535	-0.012	-0.3016	Yes
84	TOR1AIP1	TOR1AIP1 Entrez,  Source	torsin A interacting protein 1	48048	-0.013	-0.3013	Yes
85	IST1			48181	-0.014	-0.2942	Yes
86	DNAJC8	DNAJC8 Entrez,  Source	DnaJ (Hsp40) homolog, subfamily C, member 8	48522	-0.014	-0.2902	Yes
87	HNRNPH3			48622	-0.015	-0.2819	Yes
88	CYHR1	CYHR1 Entrez,  Source	cysteine/histidine-rich 1	49004	-0.015	-0.2779	Yes
89	NFYB	NFYB Entrez,  Source	nuclear transcription factor Y, beta	49056	-0.016	-0.2681	Yes
90	B4GALT3	B4GALT3 Entrez,  Source	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	49395	-0.016	-0.2627	Yes
91	COX7A2L	COX7A2L Entrez,  Source	cytochrome c oxidase subunit VIIa polypeptide 2 like	49768	-0.017	-0.2572	Yes
92	EIF4A2	EIF4A2 Entrez,  Source	eukaryotic translation initiation factor 4A, isoform 2	49960	-0.018	-0.2483	Yes
93	AATF	AATF Entrez,  Source	apoptosis antagonizing transcription factor	50043	-0.018	-0.2373	Yes
94	ARFGAP2			50094	-0.018	-0.2256	Yes
95	SLC25A36	SLC25A36 Entrez,  Source	solute carrier family 25, member 36	50130	-0.018	-0.2136	Yes
96	TAF9	TAF9 Entrez,  Source	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	51137	-0.021	-0.2166	Yes
97	STK19	STK19 Entrez,  Source	serine/threonine kinase 19	51163	-0.021	-0.2023	Yes
98	OTUB1	OTUB1 Entrez,  Source	OTU domain, ubiquitin aldehyde binding 1	51275	-0.022	-0.1893	Yes
99	DRG2	DRG2 Entrez,  Source	developmentally regulated GTP binding protein 2	51404	-0.022	-0.1762	Yes
100	AGPAT1	AGPAT1 Entrez,  Source	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	51666	-0.023	-0.1649	Yes
101	MKRN1	MKRN1 Entrez,  Source	makorin, ring finger protein, 1	52050	-0.024	-0.1548	Yes
102	SUMO2	SUMO2 Entrez,  Source	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	52344	-0.025	-0.1423	Yes
103	PRKRA	PRKRA Entrez,  Source	protein kinase, interferon-inducible double stranded RNA dependent activator	52460	-0.026	-0.1264	Yes
104	RPS27A	RPS27A Entrez,  Source	ribosomal protein S27a	52471	-0.026	-0.1087	Yes
105	NACA	NACA Entrez,  Source	nascent-polypeptide-associated complex alpha polypeptide	52561	-0.026	-0.0920	Yes
106	GNB5	GNB5 Entrez,  Source	guanine nucleotide binding protein (G protein), beta 5	52939	-0.028	-0.0792	Yes
107	CNBP	CNBP Entrez,  Source	CCHC-type zinc finger, nucleic acid binding protein	53086	-0.029	-0.0619	Yes
108	DRG1	DRG1 Entrez,  Source	developmentally regulated GTP binding protein 1	53319	-0.030	-0.0453	Yes
109	NUBP1	NUBP1 Entrez,  Source	nucleotide binding protein 1 (MinD homolog, E. coli)	55330	-0.045	-0.0492	Yes
110	TBCC	TBCC Entrez,  Source	tubulin-specific chaperone c	56086	-0.056	-0.0234	Yes
111	ZNHIT3	ZNHIT3 Entrez,  Source	zinc finger, HIT type 3	56511	-0.066	0.0147	Yes

Fig 2: MORF_TERF2IP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: MORF_TERF2IP: Random ES distribution   
Gene set null distribution of ES for MORF_TERF2IP