Details for gene set KEGG_FOCAL_ADHESION[GSEA]

Table: GSEA Results Summary

Dataset	NOV0135_D11_log2foldchange_preranked
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	KEGG_FOCAL_ADHESION
Enrichment Score (ES)	0.46512848
Normalized Enrichment Score (NES)	2.0413134
Nominal p-value	0.0
FDR q-value	0.0039823786
FWER p-Value	0.044

Fig 1: Enrichment plot: KEGG_FOCAL_ADHESION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ITGA11			23	7.335	0.0314	Yes
2	PIK3CG			77	6.226	0.0572	Yes
3	RAC2			415	4.352	0.0671	Yes
4	COL3A1			444	4.306	0.0851	Yes
5	COL5A3			469	4.243	0.1030	Yes
6	IGF1			516	4.178	0.1200	Yes
7	CAV1			808	3.647	0.1280	Yes
8	FN1			1255	3.216	0.1300	Yes
9	PARVG			1269	3.190	0.1436	Yes
10	COL5A1			1472	3.013	0.1512	Yes
11	COMP			1555	2.891	0.1616	Yes
12	ITGA10			1582	2.841	0.1733	Yes
13	CAV2			1678	2.742	0.1827	Yes
14	ITGB3			2077	2.717	0.1838	Yes
15	COL1A2			2328	2.443	0.1877	Yes
16	COL6A3			2337	2.421	0.1980	Yes
17	SPP1			2343	2.416	0.2085	Yes
18	KDR			2360	2.393	0.2185	Yes
19	COL6A2			2413	2.363	0.2274	Yes
20	MYL9			2439	2.323	0.2369	Yes
21	FLNA			2491	2.297	0.2455	Yes
22	VTN			3008	2.239	0.2413	Yes
23	ITGA4			3094	2.181	0.2485	Yes
24	COL1A1			3148	2.121	0.2563	Yes
25	PDGFRB			3203	2.095	0.2640	Yes
26	CCND3			3214	2.085	0.2728	Yes
27	PDGFB			3261	2.051	0.2806	Yes
28	FLT1			3266	2.049	0.2894	Yes
29	ITGA3			3450	1.946	0.2929	Yes
30	VEGFC			4748	1.925	0.2660	Yes
31	PDGFRA			4926	1.860	0.2693	Yes
32	BIRC3			4951	1.836	0.2767	Yes
33	ZYX			5109	1.784	0.2802	Yes
34	ITGA1			5116	1.782	0.2879	Yes
35	COL4A1			5119	1.780	0.2956	Yes
36	BAD			5181	1.749	0.3016	Yes
37	ACTB			5182	1.748	0.3092	Yes
38	PRKCA			5198	1.740	0.3164	Yes
39	SHC1			5249	1.720	0.3226	Yes
40	ACTG1			5260	1.715	0.3298	Yes
41	PPP1CA			5284	1.708	0.3366	Yes
42	HGF			5322	1.689	0.3430	Yes
43	ITGA5			5362	1.671	0.3493	Yes
44	BCAR1			5403	1.655	0.3554	Yes
45	HRAS			5413	1.652	0.3624	Yes
46	COL4A2			5574	1.601	0.3650	Yes
47	LAMC2			5931	1.498	0.3619	Yes
48	MYLK3			5997	1.473	0.3665	Yes
49	MYL7			6013	1.469	0.3726	Yes
50	LAMC3			6145	1.432	0.3753	Yes
51	MYLPF			6154	1.430	0.3813	Yes
52	VASP			6169	1.426	0.3871	Yes
53	TLN1			6213	1.413	0.3922	Yes
54	COL6A1			6238	1.407	0.3976	Yes
55	LAMB3			6408	1.364	0.3990	Yes
56	ACTN1			6444	1.359	0.4040	Yes
57	THBS2			6744	1.310	0.4016	Yes
58	ELK1			6801	1.296	0.4057	Yes
59	VWF			6846	1.287	0.4102	Yes
60	MYLK2			6883	1.280	0.4148	Yes
61	CAV3			6905	1.275	0.4198	Yes
62	ITGA9			6962	1.264	0.4238	Yes
63	AKT1			6971	1.262	0.4291	Yes
64	MAPK3			7075	1.240	0.4317	Yes
65	RAC3			7089	1.236	0.4367	Yes
66	COL11A2			7169	1.218	0.4399	Yes
67	MYL10			7286	1.202	0.4420	Yes
68	ACTN4			7372	1.199	0.4449	Yes
69	PARVA			7810	1.120	0.4379	Yes
70	FLNB			7819	1.118	0.4426	Yes
71	JUN			7866	1.109	0.4462	Yes
72	RHOA			7894	1.106	0.4503	Yes
73	TNC			7915	1.104	0.4546	Yes
74	SHC3			8134	1.066	0.4533	Yes
75	PIK3CD			8342	1.031	0.4522	Yes
76	PAK4			8430	1.018	0.4543	Yes
77	PGF			8500	1.007	0.4568	Yes
78	GRB2			8587	0.992	0.4588	Yes
79	LAMA4			8753	0.966	0.4585	Yes
80	TLN2			8980	0.938	0.4564	Yes
81	LAMC1			9059	0.924	0.4584	Yes
82	CAPN2			9067	0.923	0.4622	Yes
83	THBS1			9361	0.885	0.4581	Yes
84	PIP5K1C			9401	0.880	0.4609	Yes
85	PXN			9579	0.858	0.4598	Yes
86	PARVB			9590	0.857	0.4633	Yes
87	RAPGEF1			9660	0.850	0.4651	Yes
88	MYL12A			10263	0.788	0.4522	No
89	TNN			10349	0.780	0.4533	No
90	VEGFB			10412	0.773	0.4550	No
91	PDGFA			10628	0.749	0.4524	No
92	ITGB4			10912	0.726	0.4479	No
93	ITGA2			11125	0.697	0.4451	No
94	PIK3R2			11165	0.694	0.4471	No
95	ERBB2			11236	0.688	0.4482	No
96	PIK3R3			11277	0.683	0.4501	No
97	FLT4			11287	0.682	0.4528	No
98	ILK			11325	0.678	0.4548	No
99	VCL			11326	0.678	0.4578	No
100	DIAPH1			11372	0.671	0.4595	No
101	LAMA3			11453	0.662	0.4602	No
102	EGFR			11542	0.651	0.4606	No
103	FLNC			11634	0.641	0.4610	No
104	AKT2			11660	0.638	0.4631	No
105	LAMB2			11830	0.614	0.4612	No
106	ITGB7			12042	0.594	0.4580	No
107	THBS3			12182	0.579	0.4567	No
108	ITGB1			12370	0.555	0.4541	No
109	VAV2			13229	0.489	0.4329	No
110	SRC			13273	0.485	0.4338	No
111	ITGB8			13335	0.476	0.4342	No
112	RAF1			13339	0.476	0.4362	No
113	RASGRF1			13347	0.475	0.4381	No
114	CDC42			13591	0.448	0.4335	No
115	PDGFC			14435	0.386	0.4122	No
116	RAC1			14658	0.363	0.4077	No
117	ITGA8			14808	0.345	0.4052	No
118	FYN			14842	0.340	0.4058	No
119	PRKCB			15061	0.317	0.4012	No
120	MYL5			15130	0.309	0.4007	No
121	ITGB5			15192	0.303	0.4004	No
122	PDPK1			15482	0.277	0.3937	No
123	CRKL			15584	0.266	0.3921	No
124	MAP2K1			16237	0.199	0.3753	No
125	SHC2			16286	0.193	0.3748	No
126	MYL12B			16368	0.189	0.3734	No
127	IGF1R			17207	0.095	0.3510	No
128	COL11A1			17329	0.081	0.3481	No
129	ITGA6			17332	0.081	0.3484	No
130	CTNNB1			18080	-0.004	0.3280	No
131	CCND2			18346	-0.028	0.3209	No
132	MAPK1			18358	-0.029	0.3208	No
133	LAMA1			18555	-0.051	0.3157	No
134	ITGAV			18713	-0.069	0.3117	No
135	PAK1			18748	-0.073	0.3111	No
136	LAMA5			18877	-0.085	0.3080	No
137	PIK3R5			18946	-0.090	0.3065	No
138	RELN			18953	-0.090	0.3067	No
139	RAP1A			19126	-0.107	0.3025	No
140	COL6A6			19212	-0.116	0.3007	No
141	COL4A6			19436	-0.138	0.2952	No
142	CCND1			19463	-0.141	0.2952	No
143	DOCK1			19647	-0.162	0.2909	No
144	CRK			19873	-0.186	0.2856	No
145	PAK2			19880	-0.186	0.2862	No
146	ARHGAP35			19964	-0.191	0.2848	No
147	MAPK9			20044	-0.199	0.2835	No
148	ACTN2			20441	-0.238	0.2738	No
149	MYLK			20442	-0.238	0.2748	No
150	VAV1			20472	-0.240	0.2751	No
151	CHAD			20501	-0.243	0.2754	No
152	COL4A4			20885	-0.282	0.2662	No
153	RAP1B			21154	-0.306	0.2602	No
154	COL2A1			21231	-0.315	0.2595	No
155	PTEN			21651	-0.360	0.2497	No
156	SHC4			21764	-0.373	0.2483	No
157	PPP1CC			22752	-0.460	0.2234	No
158	PAK3			22753	-0.460	0.2254	No
159	ITGA7			23074	-0.492	0.2188	No
160	TNR			23510	-0.530	0.2093	No
161	PTK2			23590	-0.540	0.2095	No
162	VAV3			24073	-0.592	0.1990	No
163	GSK3B			24264	-0.615	0.1965	No
164	PIK3CB			24695	-0.651	0.1877	No
165	COL5A2			24734	-0.655	0.1895	No
166	BIRC2			24892	-0.671	0.1881	No
167	PPP1CB			25785	-0.771	0.1672	No
168	SOS2			26045	-0.800	0.1637	No
169	PDGFD			26089	-0.806	0.1660	No
170	LAMB1			26097	-0.806	0.1694	No
171	PIK3R1			26229	-0.821	0.1694	No
172	LAMB4			26273	-0.826	0.1718	No
173	MYL2			27108	-0.838	0.1528	No
174	PIK3CA			27643	-0.860	0.1420	No
175	XIAP			27722	-0.868	0.1437	No
176	ROCK2			27828	-0.882	0.1447	No
177	LAMA2			28079	-0.914	0.1419	No
178	ITGB6			28305	-0.947	0.1399	No
179	TNXB			29385	-0.973	0.1147	No
180	AKT3			29865	-1.035	0.1062	No
181	PPP1R12A			29888	-1.038	0.1102	No
182	MET			30219	-1.073	0.1059	No
183	BCL2			30238	-1.076	0.1101	No
184	THBS4			30275	-1.084	0.1138	No
185	MAPK10			30362	-1.099	0.1163	No
186	MAPK8			30659	-1.138	0.1132	No
187	PAK6			30817	-1.168	0.1141	No
188	ROCK1			30820	-1.169	0.1191	No
189	PRKCG			30838	-1.173	0.1238	No
190	BRAF			30894	-1.182	0.1274	No
191	SOS1			31146	-1.221	0.1260	No
192	ITGA2B			31462	-1.275	0.1229	No
193	EGF			31967	-1.388	0.1153	No
194	ACTN3			32138	-1.426	0.1169	No
195	VEGFA			32146	-1.428	0.1230	No
196	ARHGAP5			32953	-1.615	0.1081	No

Fig 2: KEGG_FOCAL_ADHESION: Random ES distribution   
Gene set null distribution of ES for KEGG_FOCAL_ADHESION