Details for gene set KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS[GSEA]

Table: GSEA Results Summary

Dataset	NOV0135_D11_log2foldchange_preranked
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS
Enrichment Score (ES)	0.4939029
Normalized Enrichment Score (NES)	2.0089338
Nominal p-value	0.0
FDR q-value	0.0055750553
FWER p-Value	0.065

Fig 1: Enrichment plot: KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	C7			35	6.734	0.0435	Yes
2	HIST1H2BI			592	4.015	0.0549	Yes
3	HIST1H4D			610	3.912	0.0803	Yes
4	HIST1H3C			738	3.710	0.1013	Yes
5	HIST1H4A			793	3.702	0.1243	Yes
6	HIST1H2AH			825	3.585	0.1471	Yes
7	HIST1H2AJ			952	3.372	0.1659	Yes
8	HIST1H2BO			1329	3.062	0.1759	Yes
9	HIST1H2AB			1503	2.983	0.1909	Yes
10	HIST1H2BJ			1568	2.877	0.2082	Yes
11	HIST1H4C			1588	2.831	0.2263	Yes
12	HIST1H3F			1642	2.771	0.2432	Yes
13	HIST1H2AL			1674	2.751	0.2605	Yes
14	CD28			1690	2.725	0.2781	Yes
15	HIST1H4K			2099	2.682	0.2847	Yes
16	HIST1H3B			2213	2.555	0.2985	Yes
17	HIST2H2AC			2395	2.383	0.3093	Yes
18	TNF			2425	2.355	0.3241	Yes
19	HIST1H2BM			2434	2.331	0.3393	Yes
20	C8A			2555	2.260	0.3509	Yes
21	H2AFB1			2980	2.260	0.3543	Yes
22	HIST1H2AE			3033	2.214	0.3675	Yes
23	C3			3093	2.181	0.3803	Yes
24	HIST1H4B			3142	2.125	0.3930	Yes
25	HIST1H3I			3147	2.121	0.4069	Yes
26	HIST1H3J			3306	2.022	0.4160	Yes
27	HIST1H2AI			3335	2.022	0.4286	Yes
28	IFNG			4312	1.927	0.4148	Yes
29	HIST1H2BB			4810	1.897	0.4138	Yes
30	HIST2H2AB			4818	1.894	0.4261	Yes
31	HIST1H3A			4945	1.840	0.4348	Yes
32	HIST1H4J			5027	1.800	0.4445	Yes
33	HIST1H4L			5036	1.793	0.4561	Yes
34	HIST1H2BE			5444	1.643	0.4559	Yes
35	TRIM21			5961	1.487	0.4517	Yes
36	HIST1H3H			6115	1.439	0.4571	Yes
37	HIST1H2BK			6229	1.410	0.4633	Yes
38	ACTN1			6444	1.359	0.4665	Yes
39	H2AFX			6525	1.335	0.4731	Yes
40	HLA-DPA1			6791	1.300	0.4745	Yes
41	HIST1H2BC			6831	1.290	0.4819	Yes
42	HIST1H2AG			7069	1.242	0.4837	Yes
43	ACTN4			7372	1.199	0.4834	Yes
44	SNRPB			7542	1.173	0.4865	Yes
45	HIST1H4H			7641	1.150	0.4915	Yes
46	HIST1H2BL			7824	1.117	0.4939	Yes
47	GRIN2A			8172	1.059	0.4915	No
48	HIST1H2BG			8722	0.972	0.4830	No
49	HIST1H3G			8857	0.958	0.4857	No
50	HIST3H2A			9254	0.897	0.4808	No
51	HLA-DPB1			9610	0.855	0.4768	No
52	H2AFY			11286	0.682	0.4358	No
53	HIST1H4I			11540	0.651	0.4332	No
54	HIST2H2BF			11606	0.643	0.4357	No
55	H2AFY2			11741	0.626	0.4362	No
56	HIST1H2AC			11826	0.614	0.4380	No
57	H2AFJ			11912	0.605	0.4397	No
58	HIST2H2BE			12210	0.575	0.4354	No
59	CD40			12306	0.562	0.4365	No
60	HIST1H4E			13353	0.474	0.4112	No
61	HIST1H2BH			13403	0.469	0.4130	No
62	CD86			14050	0.402	0.3981	No
63	H2BFWT			15005	0.323	0.3743	No
64	HLA-DRB5			15871	0.240	0.3524	No
65	HLA-DRB1			16263	0.195	0.3431	No
66	C8G			16364	0.189	0.3416	No
67	HIST1H2BD			16497	0.174	0.3392	No
68	HLA-DOA			16718	0.149	0.3342	No
69	C2			16726	0.148	0.3350	No
70	H2AFZ			16796	0.140	0.3340	No
71	H3F3A			17048	0.112	0.3280	No
72	HIST4H4			17266	0.088	0.3226	No
73	HLA-DMA			17886	0.020	0.3060	No
74	H2AFV			18483	-0.043	0.2900	No
75	C9			18965	-0.091	0.2776	No
76	SNRPD3			18995	-0.091	0.2774	No
77	HIST3H2BB			19200	-0.114	0.2726	No
78	CD80			19343	-0.129	0.2696	No
79	C4A			19657	-0.164	0.2622	No
80	HIST1H3D			20128	-0.207	0.2508	No
81	HIST1H3E			20258	-0.217	0.2487	No
82	ACTN2			20441	-0.238	0.2453	No
83	C1R			20793	-0.271	0.2376	No
84	SNRPD1			21765	-0.373	0.2137	No
85	C1S			21841	-0.380	0.2141	No
86	HIST1H2BF			22301	-0.415	0.2044	No
87	HIST1H2BN			22768	-0.461	0.1948	No
88	HLA-DQB1			23006	-0.485	0.1916	No
89	HIST2H3D			23627	-0.544	0.1783	No
90	H3F3B			23775	-0.561	0.1780	No
91	H2BFM			24909	-0.672	0.1517	No
92	HIST2H4A			25021	-0.687	0.1532	No
93	H3F3C			25242	-0.709	0.1519	No
94	FCGR3B			26431	-0.838	0.1252	No
95	CD40LG			27469	-0.838	0.1025	No
96	SSB			27903	-0.891	0.0967	No
97	GRIN2B			28250	-0.940	0.0935	No
98	C6			28607	-0.952	0.0901	No
99	ELANE			29137	-0.952	0.0820	No
100	HIST3H3			30068	-1.064	0.0637	No
101	C4B			30511	-1.121	0.0591	No
102	FCGR2A			30981	-1.197	0.0543	No
103	TROVE2			31352	-1.256	0.0525	No
104	ACTN3			32138	-1.426	0.0406	No
105	HLA-DQA1			32252	-1.455	0.0472	No
106	C5			32561	-1.515	0.0488	No
107	FCGR2B			32743	-1.563	0.0542	No
108	FCGR1A			33266	-1.727	0.0514	No
109	HLA-DRA			33974	-1.871	0.0446	No
110	HLA-DOB			35842	-2.682	0.0115	No
111	HLA-DMB			35852	-2.691	0.0291	No

Fig 2: KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS: Random ES distribution   
Gene set null distribution of ES for KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS