Details for gene set KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS[GSEA]

Table: GSEA Results Summary

Dataset	NOV0135_D3.1_log2foldchange_preranked
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS
Enrichment Score (ES)	0.47169337
Normalized Enrichment Score (NES)	1.4300252
Nominal p-value	0.0040899795
FDR q-value	1.0
FWER p-Value	1.0

Fig 1: Enrichment plot: KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	C9			902	4.823	0.0092	Yes
2	CD28			1304	4.241	0.0276	Yes
3	C3			1471	4.109	0.0513	Yes
4	HIST1H2AL			1537	3.995	0.0769	Yes
5	HIST1H2BJ			2214	3.527	0.0832	Yes
6	HIST2H3D			2565	3.240	0.0961	Yes
7	HIST1H2BO			2865	3.141	0.1097	Yes
8	C8A			3034	3.088	0.1264	Yes
9	HIST1H2BG			3055	3.054	0.1467	Yes
10	ELANE			3784	2.652	0.1457	Yes
11	C6			4252	2.559	0.1508	Yes
12	ACTN2			4432	2.535	0.1635	Yes
13	HIST1H2BH			4437	2.532	0.1807	Yes
14	HIST1H2AM			4692	2.460	0.1908	Yes
15	HIST2H2BE			4815	2.448	0.2043	Yes
16	HIST1H2BB			5026	2.275	0.2143	Yes
17	HIST1H4H			5032	2.273	0.2297	Yes
18	HIST1H4L			5077	2.234	0.2438	Yes
19	TNF			5182	2.183	0.2560	Yes
20	HIST1H3H			5208	2.159	0.2701	Yes
21	HIST1H4B			5425	2.072	0.2786	Yes
22	HIST1H3F			5467	2.050	0.2915	Yes
23	HIST1H4K			5607	1.962	0.3013	Yes
24	HIST1H3B			5674	1.923	0.3127	Yes
25	HIST1H2BK			5754	1.875	0.3234	Yes
26	HIST1H2AJ			5930	1.794	0.3311	Yes
27	HIST1H4E			5945	1.787	0.3429	Yes
28	HIST1H3C			5975	1.764	0.3542	Yes
29	CD40LG			6016	1.754	0.3651	Yes
30	HIST1H2AI			6114	1.730	0.3744	Yes
31	GRIN2B			6150	1.715	0.3852	Yes
32	HIST2H4A			6170	1.706	0.3964	Yes
33	HIST1H3I			6313	1.667	0.4040	Yes
34	HIST1H2BL			6378	1.636	0.4135	Yes
35	HIST1H2AA			7231	1.632	0.4022	Yes
36	HIST1H2AE			7989	1.594	0.3931	Yes
37	H3F3C			8087	1.551	0.4012	Yes
38	HIST1H2BC			8145	1.536	0.4102	Yes
39	HIST1H2APS6			8763	1.525	0.4043	Yes
40	HIST1H3A			9308	1.486	0.4002	Yes
41	HIST1H2BF			9362	1.467	0.4088	Yes
42	HIST1H2BN			9386	1.455	0.4181	Yes
43	HIST2H2BF			9589	1.393	0.4223	Yes
44	HIST1H2BD			9801	1.321	0.4258	Yes
45	HIST1H4I			9809	1.319	0.4346	Yes
46	HIST1H3J			9997	1.254	0.4383	Yes
47	C2			10417	1.161	0.4351	Yes
48	HIST1H3G			10451	1.154	0.4422	Yes
49	H2AFB1			10515	1.145	0.4483	Yes
50	HIST3H3			10516	1.145	0.4562	Yes
51	HIST1H2BI			11077	1.061	0.4486	Yes
52	HIST4H4			11252	1.042	0.4512	Yes
53	HIST1H2AC			11324	1.021	0.4563	Yes
54	HIST1H2BE			11402	1.005	0.4611	Yes
55	HIST1H4D			11463	0.994	0.4663	Yes
56	H2AFZ			11824	0.925	0.4632	Yes
57	HIST1H4C			11837	0.923	0.4691	Yes
58	HIST2H2AB			11980	0.892	0.4715	Yes
59	HIST1H4J			12355	0.819	0.4672	Yes
60	HIST1H2AH			12652	0.771	0.4647	Yes
61	HIST1H2AG			12664	0.768	0.4697	Yes
62	HIST1H3E			12795	0.747	0.4713	Yes
63	C5			12971	0.727	0.4717	Yes
64	SSB			13218	0.685	0.4699	No
65	H2AFX			13632	0.628	0.4633	No
66	HIST3H2A			14076	0.572	0.4555	No
67	ACTN1			14336	0.544	0.4524	No
68	HIST3H2BB			14652	0.507	0.4476	No
69	SNRPB			14653	0.507	0.4510	No
70	TROVE2			15386	0.435	0.4347	No
71	SNRPD3			15527	0.422	0.4339	No
72	H2AFJ			15936	0.380	0.4257	No
73	FCGR1A			16907	0.286	0.4021	No
74	HIST2H2AC			16919	0.286	0.4038	No
75	C8G			17022	0.276	0.4030	No
76	ACTN4			17679	0.220	0.3872	No
77	HLA-DQA2			17839	0.217	0.3845	No
78	H3F3A			18071	0.204	0.3798	No
79	CD80			18155	0.198	0.3789	No
80	FCGR2A			18401	0.179	0.3737	No
81	HIST1H2AB			18760	0.155	0.3653	No
82	HIST1H4A			19810	0.110	0.3384	No
83	H3F3B			19965	0.105	0.3350	No
84	TRIM21			20036	0.101	0.3339	No
85	HLA-DQB1			20393	0.076	0.3250	No
86	HLA-DPB1			21328	0.016	0.3005	No
87	C1S			22058	-0.023	0.2814	No
88	HLA-DRB1			22710	-0.070	0.2647	No
89	HLA-DOB			23839	-0.152	0.2360	No
90	HIST1H2BM			24664	-0.214	0.2158	No
91	SNRPD1			24923	-0.233	0.2105	No
92	H2AFV			24971	-0.237	0.2109	No
93	H2AFY			25351	-0.266	0.2028	No
94	CD86			25697	-0.292	0.1957	No
95	HLA-DOA			26068	-0.320	0.1881	No
96	H2BFM			26943	-0.388	0.1677	No
97	HIST1H3D			27756	-0.459	0.1494	No
98	HLA-DPA1			28101	-0.490	0.1437	No
99	GRIN2A			28735	-0.552	0.1308	No
100	HLA-DMA			28889	-0.566	0.1306	No
101	H2BFWT			29052	-0.583	0.1303	No
102	CD40			30337	-0.741	0.1015	No
103	HLA-DRA			30481	-0.762	0.1030	No
104	C1R			30634	-0.784	0.1043	No
105	HLA-DRB5			30718	-0.798	0.1076	No
106	C4A			31282	-0.871	0.0987	No
107	ACTN3			33133	-1.276	0.0586	No
108	HLA-DQA1			34163	-1.348	0.0407	No
109	FCGR3B			34784	-1.398	0.0339	No
110	H2AFY2			35868	-1.717	0.0171	No
111	C4B			35869	-1.717	0.0288	No
112	HLA-DMB			36088	-1.865	0.0358	No
113	HIST1H4F			36591	-2.244	0.0379	No

Fig 2: KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS: Random ES distribution   
Gene set null distribution of ES for KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS