Details for gene set REACTOME_AMYLOIDS[GSEA]

Table: GSEA Results Summary

Dataset	NOV0135_D3.1_log2foldchange_preranked
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	REACTOME_AMYLOIDS
Enrichment Score (ES)	0.55471206
Normalized Enrichment Score (NES)	1.6272129
Nominal p-value	0.0
FDR q-value	0.9073654
FWER p-Value	0.929

Fig 1: Enrichment plot: REACTOME_AMYLOIDS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CALCA			1855	3.732	-0.0084	Yes
2	HIST1H2BJ			2214	3.527	0.0205	Yes
3	HIST2H3D			2565	3.240	0.0465	Yes
4	HIST1H2BO			2865	3.141	0.0727	Yes
5	HIST1H2BG			3055	3.054	0.1009	Yes
6	LTF			3166	3.018	0.1307	Yes
7	HIST1H2BH			4437	2.532	0.1248	Yes
8	HIST2H2BE			4815	2.448	0.1414	Yes
9	HIST1H2BB			5026	2.275	0.1606	Yes
10	HIST1H4H			5032	2.273	0.1851	Yes
11	HIST1H4L			5077	2.234	0.2082	Yes
12	HIST1H3H			5208	2.159	0.2283	Yes
13	HIST1H4B			5425	2.072	0.2451	Yes
14	HIST1H3F			5467	2.050	0.2662	Yes
15	HIST1H4K			5607	1.962	0.2839	Yes
16	HIST1H3B			5674	1.923	0.3030	Yes
17	HIST1H2BK			5754	1.875	0.3213	Yes
18	HIST1H2AJ			5930	1.794	0.3362	Yes
19	HIST1H4E			5945	1.787	0.3552	Yes
20	HIST1H3C			5975	1.764	0.3736	Yes
21	HIST2H4A			6170	1.706	0.3870	Yes
22	HIST1H3I			6313	1.667	0.4013	Yes
23	HIST1H2BL			6378	1.636	0.4174	Yes
24	ODAM			7873	1.628	0.3957	Yes
25	SEMG1			7958	1.606	0.4110	Yes
26	HIST1H2AE			7989	1.594	0.4275	Yes
27	HIST1H2BC			8145	1.536	0.4401	Yes
28	H3F3AP5			8762	1.525	0.4404	Yes
29	PRL			8968	1.525	0.4516	Yes
30	HIST1H3A			9308	1.486	0.4588	Yes
31	HIST1H2BF			9362	1.467	0.4733	Yes
32	HIST1H2BN			9386	1.455	0.4885	Yes
33	HIST1H2BD			9801	1.321	0.4919	Yes
34	HIST1H4I			9809	1.319	0.5061	Yes
35	HIST1H3J			9997	1.254	0.5148	Yes
36	HIST1H3G			10451	1.154	0.5154	Yes
37	HIST1H2BI			11077	1.061	0.5104	Yes
38	HIST4H4			11252	1.042	0.5172	Yes
39	HIST1H2AC			11324	1.021	0.5264	Yes
40	HIST1H2BE			11402	1.005	0.5352	Yes
41	HIST1H4D			11463	0.994	0.5444	Yes
42	H2AFZ			11824	0.925	0.5450	Yes
43	HIST1H4C			11837	0.923	0.5547	Yes
44	HIST1H4J			12355	0.819	0.5500	No
45	HIST1H3E			12795	0.747	0.5465	No
46	H2AFX			13632	0.628	0.5313	No
47	LYZ			13708	0.618	0.5361	No
48	HIST3H2BB			14652	0.507	0.5167	No
49	SNCA			14706	0.502	0.5208	No
50	FGA			14902	0.483	0.5209	No
51	GSN			15361	0.437	0.5136	No
52	HIST2H2AC			16919	0.286	0.4756	No
53	SAA1			17471	0.237	0.4637	No
54	CST3			17546	0.230	0.4643	No
55	H3F3A			18071	0.204	0.4527	No
56	H3F3AP6			18211	0.194	0.4511	No
57	IAPP			18454	0.177	0.4466	No
58	HIST1H2AB			18760	0.155	0.4403	No
59	HIST1H4A			19810	0.110	0.4138	No
60	B2M			19951	0.106	0.4113	No
61	H3F3B			19965	0.105	0.4121	No
62	APOA1			20251	0.085	0.4055	No
63	ITM2B			22030	-0.022	0.3589	No
64	TTR			22949	-0.087	0.3357	No
65	HIST1H2BM			24664	-0.214	0.2928	No
66	HSPG2			25773	-0.298	0.2669	No
67	TGFBI			27056	-0.396	0.2374	No
68	APP			27369	-0.425	0.2338	No
69	HIST1H3D			27756	-0.459	0.2286	No
70	NPPA			29613	-0.649	0.1868	No
71	MFGE8			31977	-0.971	0.1351	No
72	HIST1H4F			36591	-2.244	0.0379	No

Fig 2: REACTOME_AMYLOIDS: Random ES distribution   
Gene set null distribution of ES for REACTOME_AMYLOIDS