Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | NS50719_832_collapsed_to_symbols.NS50719_832.cls #arhinia_versus_control.NS50719_832.cls #arhinia_versus_control_repos |
| Phenotype | NS50719_832.cls#arhinia_versus_control_repos |
| Upregulated in class | 1 |
| GeneSet | GO_PRESYNAPTIC_ACTIVE_ZONE |
| Enrichment Score (ES) | 0.66602266 |
| Normalized Enrichment Score (NES) | 1.7791868 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.6651597 |
| FWER p-Value | 0.992 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RIMS1 | RIMS1 Entrez, Source | regulating synaptic membrane exocytosis 1 | 119 | 0.857 | 0.1771 | Yes |
| 2 | PPFIA4 | PPFIA4 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 750 | 0.466 | 0.2420 | Yes |
| 3 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 1003 | 0.399 | 0.3135 | Yes |
| 4 | PPFIA2 | PPFIA2 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 | 1074 | 0.383 | 0.3917 | Yes |
| 5 | ADORA1 | ADORA1 Entrez, Source | adenosine A1 receptor | 1126 | 0.372 | 0.4685 | Yes |
| 6 | SLC17A7 | SLC17A7 Entrez, Source | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | 1130 | 0.371 | 0.5478 | Yes |
| 7 | PCLO | PCLO Entrez, Source | piccolo (presynaptic cytomatrix protein) | 1926 | 0.252 | 0.5577 | Yes |
| 8 | DGKI | DGKI Entrez, Source | diacylglycerol kinase, iota | 2190 | 0.225 | 0.5914 | Yes |
| 9 | SYP | SYP Entrez, Source | synaptophysin | 2241 | 0.219 | 0.6356 | Yes |
| 10 | SYN1 | SYN1 Entrez, Source | synapsin I | 2461 | 0.198 | 0.6660 | Yes |
| 11 | FZD3 | FZD3 Entrez, Source | frizzled homolog 3 (Drosophila) | 4442 | 0.095 | 0.5767 | No |
| 12 | BSN | BSN Entrez, Source | bassoon (presynaptic cytomatrix protein) | 4721 | 0.086 | 0.5798 | No |
| 13 | ERC1 | ERC1 Entrez, Source | ELKS/RAB6-interacting/CAST family member 1 | 5124 | 0.075 | 0.5736 | No |
| 14 | PPFIA1 | PPFIA1 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 5311 | 0.071 | 0.5784 | No |
| 15 | SV2A | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 5730 | 0.061 | 0.5684 | No |
| 16 | UNC13A | UNC13A Entrez, Source | unc-13 homolog A (C. elegans) | 5754 | 0.061 | 0.5801 | No |
| 17 | NCOA2 | NCOA2 Entrez, Source | nuclear receptor coactivator 2 | 5864 | 0.058 | 0.5865 | No |
| 18 | RIMS4 | RIMS4 Entrez, Source | regulating synaptic membrane exocytosis 4 | 5978 | 0.056 | 0.5923 | No |
| 19 | PPFIA3 | PPFIA3 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 | 6722 | 0.042 | 0.5601 | No |
| 20 | UNC13B | UNC13B Entrez, Source | unc-13 homolog B (C. elegans) | 6724 | 0.042 | 0.5691 | No |
| 21 | ERC2 | ERC2 Entrez, Source | ELKS/RAB6-interacting/CAST family member 2 | 7619 | 0.027 | 0.5254 | No |
| 22 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 10447 | -0.015 | 0.3722 | No |
| 23 | RIMS3 | RIMS3 Entrez, Source | regulating synaptic membrane exocytosis 3 | 11831 | -0.040 | 0.3043 | No |
| 24 | SLC32A1 | SLC32A1 Entrez, Source | solute carrier family 32 (GABA vesicular transporter), member 1 | 13664 | -0.098 | 0.2239 | No |
| 25 | RIMS2 | RIMS2 Entrez, Source | regulating synaptic membrane exocytosis 2 | 13715 | -0.100 | 0.2425 | No |
